BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15644954|ref|NP_207124.1| CMP-N-acetylneuraminic acid
synthetase (neuA) [Helicobacter pylori 26695]
         (517 letters)

Database: NC_000921.faa
           1491 sequences; 494,079 total letters

Searching...done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_222936.1|  3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSF...    35  0.005
ref|NP_223363.1|  Outer membrane protein/porin [Helicobacter...    29  0.33
ref|NP_223450.1|  putative Outer membrane protein [Helicobac...    28  0.43
ref|NP_223348.1|  putative TYPE II RESTRICTION ENZYME [Helic...    28  0.56
ref|NP_223725.1|  putative outer membrane protein [Helicobac...    28  0.73
ref|NP_224011.1|  ATP-DEPENDENT PROTEASE LA [Helicobacter py...    27  1.6
ref|NP_223272.1|  putative efflux transporter [Helicobacter ...    27  1.6
ref|NP_223574.1|  putative vacuolating cytotoxin (VacA) para...    26  2.1
ref|NP_223056.1|  transketolase [Helicobacter pylori J99]          26  2.1
ref|NP_223294.1|  Hydrogenase, cytochrome subunit [Helicobac...    25  4.7
ref|NP_222935.1|  Outer membrane protein/porin [Helicobacter...    25  4.7
ref|NP_224141.1|  TYPE I RESTRICTION ENZYME (MODIFICATION SU...    25  6.2
ref|NP_224129.1|  TYPE III DNA MODIFICATION ENZYME (METHYLTR...    25  6.2
ref|NP_223231.1|  DIAMINOPIMELATE EPIMERASE [Helicobacter py...    25  6.2
ref|NP_222992.1|  ATP-DEPENDENT ZINC METALLOPEPTIDASE [Helic...    25  6.2
ref|NP_223663.1|  putative [Helicobacter pylori J99]               24  8.1
ref|NP_223081.1|  GLUCOSE INHIBITED DIVISION PROTEIN B [Heli...    24  8.1
ref|NP_222746.1|  putative [Helicobacter pylori J99]               24  8.1
>ref|NP_222936.1| 3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE [Helicobacter
           pylori J99]
          Length = 243

 Score = 35.0 bits (79), Expect = 0.005
 Identities = 28/130 (21%), Positives = 57/130 (43%), Gaps = 11/130 (8%)

Query: 6   IVLARSSSKRIKNKNIIDFFNKPMLAYPIEVALNSKLFEKVFISSDSMEYVNLAKNYGAS 65
           I+ AR  S R +NK + D F  PM+   +  A N+ L ++  ++ D    +   + +   
Sbjct: 3   IIPARLKSSRFENKMLEDIFGLPMV---VRCAKNANLVDECVVACDDESIMKACQKF--- 56

Query: 66  FLNLRPKILADDRATTLEVMAYHMEELELKDEDIACCLYGASALLQEKHLKNAFETLNKN 125
             +++  + +    +  E      + L LK+++    L G    L++K +      L   
Sbjct: 57  --HIKAVLTSKHHNSGTERCLEAAQILGLKNDERVLNLQGDEPFLEKKVI---LALLEAT 111

Query: 126 QNTDYVFTCS 135
           QN  ++ TC+
Sbjct: 112 QNAPFMATCA 121
>ref|NP_223363.1| Outer membrane protein/porin [Helicobacter pylori J99]
          Length = 270

 Score = 28.9 bits (63), Expect = 0.33
 Identities = 12/28 (42%), Positives = 16/28 (56%)

Query: 325 KILNFTLNALKHYHHLSKDYQYYLGVGF 352
           K L+   NA   Y+HL +DY  YLG  +
Sbjct: 241 KFLSAGPNATNLYYHLKRDYSLYLGYNY 268
>ref|NP_223450.1| putative Outer membrane protein [Helicobacter pylori J99]
          Length = 278

 Score = 28.5 bits (62), Expect = 0.43
 Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 314 EHAKGFYPKNTKILNFTLNAL----KHYHHLSKDYQYYLGVGFYPVDARFIYDRPINT 367
           ++A GF+ KN   L  +L A     K Y    +  + ++   FY V A F+Y R   T
Sbjct: 129 DYAYGFFLKNKGALGDSLRASSQIPKSYREKLQRKETFINAIFYGVGADFLYKRAFGT 186
>ref|NP_223348.1| putative TYPE II RESTRICTION ENZYME [Helicobacter pylori J99]
          Length = 290

 Score = 28.1 bits (61), Expect = 0.56
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 15/89 (16%)

Query: 323 NTKILNFTLNALKHY-----HHLSKD---YQYYLGVGFYPVDARFIYDRPINT------- 367
           NT+ L+F ++  K       H  S D   YQ Y+     P D   +    I T       
Sbjct: 30  NTEFLDFAISFFKDIVYAKMHDKSIDFSWYQQYVMDNKDPKDIAILCGTNIKTIFNTYGT 89

Query: 368 ENKEVLITLGGSEQKTLKEIVKILENKNV 396
             KEV++ +  +  K L EI++ LEN N+
Sbjct: 90  STKEVVLDIAQNNLKYLYEILQNLENDNM 118
>ref|NP_223725.1| putative outer membrane protein [Helicobacter pylori J99]
          Length = 751

 Score = 27.7 bits (60), Expect = 0.73
 Identities = 28/112 (25%), Positives = 42/112 (37%), Gaps = 9/112 (8%)

Query: 340 LSKDYQYYLGVGFYPVDARFIYDRPINTENKEVLITL-----GGSEQKTLKEIVKILENK 394
           + KD Q  L    +     F  D P N++  + L T        + Q   +++ +I  N 
Sbjct: 181 IPKDSQIILPASLFN---NFSNDSPFNSDGLQQLQTTTTPFSDANTQSLFEKLSQITTNL 237

Query: 395 NVNLHIISPYTPKNPPKNTHYYSPLNPLEFSSLMKSCACA-ISAAGQTLYEL 445
            +      P++  N   N    SP    E     KSC  A +S   QT  EL
Sbjct: 238 QMTYENTDPFSSGNNDPNGPLASPKPHYECPGYKKSCQVASVSFTPQTAEEL 289
>ref|NP_224011.1| ATP-DEPENDENT PROTEASE LA [Helicobacter pylori J99]
          Length = 831

 Score = 26.6 bits (57), Expect = 1.6
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 13/81 (16%)

Query: 379 SEQKTLKEIVKILENKNVNLHIISPYTPKNPPKNTHYYSPLNPLEFSSLMKSCAC--AIS 436
           +E K  K+++K+    +++LH+    TPK+         P   +  +S+M S  C  AI 
Sbjct: 705 AENKKKKKVLKVYNAYDLHLHVPEGATPKD--------GPSAGIAMASVMASILCDRAIR 756

Query: 437 AAGQTLYELALSQTPSLILPI 457
           +      EL LS     +LPI
Sbjct: 757 SEVAMTGELTLS---GEVLPI 774
>ref|NP_223272.1| putative efflux transporter [Helicobacter pylori J99]
          Length = 1028

 Score = 26.6 bits (57), Expect = 1.6
 Identities = 24/123 (19%), Positives = 45/123 (36%), Gaps = 11/123 (8%)

Query: 40  SKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKILADDRATTLEVMAYHMEELELKDEDI 99
           SK+F+K     D +E+  L   YG +    + KI    +        + + + EL     
Sbjct: 567 SKIFQKAIEKHDEVEFTTLQVGYGTTQNPFKAKIFVQLKPLKERKKEHELGQFEL----- 621

Query: 100 ACCLYGASALLQEKHLKNAFETLNKNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHS 159
                  SAL +E       + L+    ++         +SP+++F   +  +   K   
Sbjct: 622 ------MSALKKELKSMPEAKDLDSINLSEVALIGGGGDSSPFQTFVFSHSQEAVDKSVE 675

Query: 160 NTR 162
           N R
Sbjct: 676 NLR 678
>ref|NP_223574.1| putative vacuolating cytotoxin (VacA) paralog [Helicobacter pylori
            J99]
          Length = 2399

 Score = 26.2 bits (56), Expect = 2.1
 Identities = 11/43 (25%), Positives = 26/43 (59%)

Query: 354  PVDARFIYDRPINTENKEVLITLGGSEQKTLKEIVKILENKNV 396
            P+++  IY++  ++EN + L+ +      TLKE+++  +  N+
Sbjct: 1214 PLNSLNIYNKGFSSENLKTLLGILSQNSATLKEMIESNQLDNI 1256
>ref|NP_223056.1| transketolase [Helicobacter pylori J99]
          Length = 641

 Score = 26.2 bits (56), Expect = 2.1
 Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 2/40 (5%)

Query: 365 INTENKEVLITL--GGSEQKTLKEIVKILENKNVNLHIIS 402
           +   +K+ +ITL   GSE     E  KILE +N+   ++S
Sbjct: 525 VKHHSKDPIITLVASGSEVSLALESAKILERENIPTQVVS 564
>ref|NP_223294.1| Hydrogenase, cytochrome subunit [Helicobacter pylori J99]
          Length = 224

 Score = 25.0 bits (53), Expect = 4.7
 Identities = 15/46 (32%), Positives = 20/46 (42%)

Query: 302 EKAKSLMVIEDTEHAKGFYPKNTKILNFTLNALKHYHHLSKDYQYY 347
           ++ K+  +I D  H KG Y     +  FTL  L     LS    YY
Sbjct: 105 DQMKAYFLISDKPHTKGLYNPIQLVAYFTLVVLIVLMSLSGIVLYY 150
>ref|NP_222935.1| Outer membrane protein/porin [Helicobacter pylori J99]
          Length = 483

 Score = 25.0 bits (53), Expect = 4.7
 Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 11/48 (22%)

Query: 121 TLNKNQNTDYVFTCSPFSASPYRSFSLEN-----------GVQMAFKE 157
           +LN+ Q + +  T   F  +P+RS  L N           GVQ+ +K+
Sbjct: 285 SLNETQYSQFQTTTKEFGHNPFRSVGLINSQSNNGAMNGVGVQLGYKQ 332
>ref|NP_224141.1| TYPE I RESTRICTION ENZYME (MODIFICATION SUBUNIT) [Helicobacter
           pylori J99]
          Length = 815

 Score = 24.6 bits (52), Expect = 6.2
 Identities = 14/52 (26%), Positives = 26/52 (49%), Gaps = 2/52 (3%)

Query: 441 TLYELALSQTPSLILPIASNQIIQSKEFESLGIFKQTSLKTLAKDFENLQIQ 492
           T  +L     P  ++    ++++  KEFE +GI  +  +  L KD+ N  +Q
Sbjct: 537 TFNDLEPGFNPKTLIESVCSKVL--KEFEKVGILDKYGVYQLFKDYYNEVLQ 586
>ref|NP_224129.1| TYPE III DNA MODIFICATION ENZYME (METHYLTRANSFERASE) [Helicobacter
           pylori J99]
          Length = 641

 Score = 24.6 bits (52), Expect = 6.2
 Identities = 27/103 (26%), Positives = 40/103 (38%), Gaps = 16/103 (15%)

Query: 296 DFYLLKEKAKSLMVIEDTEHAKGFYPKNTKILN--------------FTLNALK--HYHH 339
           DF  +KE+   L  +         + KN KIL                 L+ALK     +
Sbjct: 49  DFSEIKEEGYGLDFVGKKIALNQAFKKNHKILKPLNESTSKHILIKGDNLDALKILKQSY 108

Query: 340 LSKDYQYYLGVGFYPVDARFIYDRPINTENKEVLITLGGSEQK 382
             K    Y+   +   +  FIY    +  N+EVL TL  S++K
Sbjct: 109 SEKIKMIYIDPPYNTKNDNFIYGDDFSQSNEEVLKTLDYSKEK 151
>ref|NP_223231.1| DIAMINOPIMELATE EPIMERASE [Helicobacter pylori J99]
          Length = 273

 Score = 24.6 bits (52), Expect = 6.2
 Identities = 42/168 (25%), Positives = 65/168 (38%), Gaps = 24/168 (14%)

Query: 281 GNDFLITDSYCLNSKDFYLLKEK---------AKSLMVI---EDTEHAKGFYPKNTKILN 328
           GNDFLIT S+    KDF  L ++         A  L+V+   +D ++   FY  +     
Sbjct: 10  GNDFLITQSF--KKKDFSNLAQQVCHRHEGFGADGLVVVLPSKDYDYEWDFYNSDGSKAG 67

Query: 329 FTLNA-----LKHYHHLSKDYQYYLGVGFYPVDARFIYDRPI--NTENKEVLITLGGSEQ 381
              NA     L  Y H     ++    G   +  R      +  N  N ++L T+     
Sbjct: 68  MCGNASRCVGLFAYQHAIAPKEHVFLAGKREISIRIEEPNIVESNLGNYQILDTIPNLRC 127

Query: 382 KTLKEIVKILENKNVNLHIISPYTPK--NPPKNTHYYSPLNPLEFSSL 427
           K       +LEN  +  ++I+   P      KN    + LN LE  +L
Sbjct: 128 KKFFTNNSVLENIPM-FYLINTGVPHLVGFVKNKGLLNSLNTLELRAL 174
>ref|NP_222992.1| ATP-DEPENDENT ZINC METALLOPEPTIDASE [Helicobacter pylori J99]
          Length = 550

 Score = 24.6 bits (52), Expect = 6.2
 Identities = 27/114 (23%), Positives = 52/114 (44%), Gaps = 12/114 (10%)

Query: 12  SSKRIKNKNIIDFFNKPMLAYPIEVALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRP 71
           +  +I +++ I  + K  L+  I + L  K  E+  +S   ++       + AS L L P
Sbjct: 446 NENKIHSESEIKNYIKVYLSGTIILELLYK--ERYSLSKQDLQKAKFLNEFMASELLLAP 503

Query: 72  KILADDRATTLEVMAYHMEELELKDEDIACCLYGASALLQEKHLKNA--FETLN 123
                   T   +   + E+LE     IA C   ++ LL+++ L++A  ++ LN
Sbjct: 504 --------TKESLSVLYEEQLEFLKPQIAACKRLSALLLEQECLEHANFYDLLN 549
>ref|NP_223663.1| putative [Helicobacter pylori J99]
          Length = 145

 Score = 24.3 bits (51), Expect = 8.1
 Identities = 12/29 (41%), Positives = 18/29 (61%), Gaps = 2/29 (6%)

Query: 327 LNFTLNALKHYHHLSKDYQYYLGV--GFY 353
           +N T + LK+  HLS DY  Y+ +  G+Y
Sbjct: 62  INRTQSVLKNELHLSNDYLKYVEIHQGYY 90
>ref|NP_223081.1| GLUCOSE INHIBITED DIVISION PROTEIN B [Helicobacter pylori J99]
          Length = 178

 Score = 24.3 bits (51), Expect = 8.1
 Identities = 23/101 (22%), Positives = 41/101 (39%), Gaps = 19/101 (18%)

Query: 419 LNPLEFSSLMKSCACAISAAGQTLYELALSQTPS-------------------LILPIAS 459
           L PLEF    KSC    S AG     LAL +  +                    +LP+ +
Sbjct: 38  LKPLEFVKDFKSCLDIGSGAGLPAIPLALEKPEAQFILLEPRVKRAAFLNYLKSVLPLNN 97

Query: 460 NQIIQSKEFESLGIFKQTSLKTLAKDFENLQIQKNQAWAKN 500
            +II+ +  +   + +   + + A    +  I+K+Q + K+
Sbjct: 98  IEIIKKRLEDYQNLLQVDLITSRAVASSSFLIEKSQRFLKD 138
>ref|NP_222746.1| putative [Helicobacter pylori J99]
          Length = 175

 Score = 24.3 bits (51), Expect = 8.1
 Identities = 19/72 (26%), Positives = 29/72 (39%), Gaps = 5/72 (6%)

Query: 376 LGGSEQKTLKEIVKILENKNV-----NLHIISPYTPKNPPKNTHYYSPLNPLEFSSLMKS 430
           + G E K + E      NK V     +++ +  Y PK+    T Y +      F    K 
Sbjct: 36  ISGVEVKRMNENENTPNNKEVKTLARDVYFVQTYDPKDQKSVTVYRNEDTRFGFPFYFKF 95

Query: 431 CACAISAAGQTL 442
            +  ISA  Q+L
Sbjct: 96  NSADISALAQSL 107
  Database: NC_000921.faa
    Posted date:  Dec 10, 2001  4:36 PM
  Number of letters in database: 494,079
  Number of sequences in database:  1491
  
Lambda     K      H
   0.320    0.135    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 572,608
Number of Sequences: 1491
Number of extensions: 28412
Number of successful extensions: 114
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 104
Number of HSP's gapped (non-prelim): 21
length of query: 517
length of database: 494,079
effective HSP length: 82
effective length of query: 435
effective length of database: 371,817
effective search space: 161740395
effective search space used: 161740395
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 51 (24.3 bits)