>pdb|1LPQ|A Chain A, Human Dna Topoisomerase I (70 Kda) In Non-Covalent Complex
           With A 22 Base Pair Dna Duplex Containing An 8-Oxog
           Lesion
          Length = 564

 Score = 29.3 bits (64), Expect = 0.78
 Identities = 36/187 (19%), Positives = 70/187 (37%), Gaps = 40/187 (21%)

Query: 170 QKTEQERQKTEQERQKTEQEKQKTIKTQKDFIKYVEQNCQENHNQ----FFIEKGGIKAG 225
           Q ++  + +TE  +Q +++EK K  +  +  +K       +NH +    F IE  G+  G
Sbjct: 103 QMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRG 162

Query: 226 IG------------------IEVEAECKTPKPAKTNQTPIQPKHLPNSKQPRSQRGSKAQ 267
            G                  I    + K P P             P  K    +  +K  
Sbjct: 163 RGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPP------------PGHKWKEVRHDNKVT 210

Query: 268 ELIAYLQKELESLPY----SQKAIAKQVDFYRPSSIAYLE--LDPRDFNVTEEWQKENLK 321
            L+++ +    S+ Y        I  + D+ +  +   L+  +D       E+W+ + +K
Sbjct: 211 WLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMK 270

Query: 322 IRSKAQA 328
           +R +A A
Sbjct: 271 VRQRAVA 277