>pdb|1FDW|   Human 17-Beta-Hydroxysteroid-Dehydrogenase Type 1 Mutant H221q
           Complexed With Estradiol
          Length = 327

 Score = 75.5 bits (184), Expect = 6e-15
 Identities = 66/233 (28%), Positives = 105/233 (44%), Gaps = 24/233 (10%)

Query: 5   QGYKVYALSR---------HATLCVALNHALCESVDIDVSDSNALKEVFSNISAKEKYCD 55
           Q +KVYA  R          A   +A      E++ +DV DS ++      ++  E   D
Sbjct: 28  QSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVT--EGRVD 85

Query: 56  VLINSAGYGVFGSVEDTPIEEVKKQFSVNFFALCEVVQFCLPLLKNKPHSKIFNLSSIAG 115
           VL+ +AG G+ G +E    + V     VN      ++Q  LP +K +   ++    S+ G
Sbjct: 86  VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGG 145

Query: 116 RVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIEPGPVKSNWEKTAFSVENFES- 174
            + + F   Y ASK ALE   ++L + L PF V + LIE GPV      TAF  +   S 
Sbjct: 146 LMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPV-----HTAFMEKVLGSP 200

Query: 175 EDSLYALEVNAAKSFYSGVYQN-------ALSPKAVAQKIVFLSMSQKIKARY 220
           E+ L   +++    FY  + Q+       A +P+ VA+  +    + K   RY
Sbjct: 201 EEVLDRTDIHTFHRFYQYLAQSKQVFREAAQNPEEVAEVFLTALRAPKPTLRY 253