BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15645705|ref|NP_207882.1| alpha-ketoglutarate
permease (kgtP) [Helicobacter pylori 26695]
(426 letters)
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
13,198 sequences; 2,899,336 total letters
Searching...........................done
Score E
Sequences producing significant alignments: (bits) Value
pdb|1GKT|A Chain A, Neutron Laue Diffraction Structure Of E... 26 9.8
pdb|1EPN|E Chain E, Endothia Aspartic Proteinase (Endothiap... 26 9.8
pdb|2PAH|A Chain A, Tetrameric Human Phenylalanine Hydroxyl... 26 9.8
pdb|1DMW|A Chain A, Crystal Structure Of Double Truncated H... 26 9.8
pdb|1J8T|A Chain A, Catalytic Domain Of Human Phenylalanine... 26 9.8
pdb|3PAH| Human Phenylalanine Hydroxylase Catalytic Domai... 26 9.8
pdb|1GVT|A Chain A, Endothiapepsin Complex With Cp-80,794 >... 26 9.8
>pdb|1GKT|A Chain A, Neutron Laue Diffraction Structure Of Endothiapepsin
Complexed With Transition State Analogue Inhibitor H261
Length = 329
Score = 25.8 bits (55), Expect = 9.8
Identities = 12/33 (36%), Positives = 17/33 (51%)
Query: 376 IANALFGGSASYVALEFKQHGFEWGFVGYVMFS 408
I + GS +Y A+ KQ +EW GY + S
Sbjct: 173 IDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGS 205
>pdb|1EPN|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Cp-80,794 (Mor Phe
Cys+ch3 Nor)
pdb|1EPM|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Ps2 (Thr Phe Gln Ala Psa
Leu Arg Glu)
pdb|2ER7|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With H-261
pdb|3ER5|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) H-189 Complex
pdb|5ER2|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With Cp-69,799
pdb|1EPP|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22)complexed With Pd-130,693 (Mas Phe
Lys+mtf Sta Mba)
pdb|1EPQ|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Pd-133,450 (Sot Phe
Gly+scc Gcl)
pdb|1ENT|E Chain E, Endothiapepsin (E.C.3.4.23.22) Complex With The Inhibitor
Pd130328
pdb|4ER2|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With Pepstatin
pdb|1EED|P Chain P, Endothiapepsin (E.C.3.4.23.22) Complex With The Cyclohexyl
Renin Inhibitor Pd125754
pdb|1EPL|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Ps1 (Pro Leu Glu Psa Arg
Leu)
pdb|1EPO|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Cp-81,282 (Mor Phe Nle
Chf Nme)
pdb|1ER8|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With H-77
pdb|2ER6|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With H-256
pdb|3ER3|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With Cp-71,362
pdb|4ER1|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With PD125967
pdb|5ER1|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Bw624 Complex
pdb|1E80|E Chain E, Endothiapepsin Complex With Renin Inhibitor
Merck-Kgaa-Emd56133
pdb|1E5O|E Chain E, Endothiapepsin Complex With Inhibitor Db2
pdb|1E81|E Chain E, Endothiapepsin Complex With Renin Inhibitor
Merck-Kgaa-Emd61395
pdb|1E82|E Chain E, Endothiapepsin Complex With Renin Inhibitor
Merck-Kgaa-Emd59601
pdb|4ER4|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) H-142 Complex
pdb|4APE| Acid Proteinase (E.C.3.4.23.10), Endothiapepsin
pdb|2ER9|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With L363,564
pdb|1EPR|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.22) Complexed With Pd-135,040 (Tsm Dph His
Chf Emr)
pdb|2ER0|E Chain E, Endothia Aspartic Proteinase (Endothiapepsin)
(E.C.3.4.23.6) Complex With L364,099
Length = 330
Score = 25.8 bits (55), Expect = 9.8
Identities = 12/33 (36%), Positives = 17/33 (51%)
Query: 376 IANALFGGSASYVALEFKQHGFEWGFVGYVMFS 408
I + GS +Y A+ KQ +EW GY + S
Sbjct: 174 IDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGS 206
>pdb|2PAH|A Chain A, Tetrameric Human Phenylalanine Hydroxylase
pdb|2PAH|B Chain B, Tetrameric Human Phenylalanine Hydroxylase
Length = 335
Score = 25.8 bits (55), Expect = 9.8
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 21 NLVEWYDFYAYAFLAPYFAKE--FTHTNDPTLALISAFLVFMLGFFMRPLGSL 71
+L + + Y Y + P K F N P L +S FL GF +RP+ L
Sbjct: 79 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGL 131
>pdb|1DMW|A Chain A, Crystal Structure Of Double Truncated Human Phenylalanine
Hydroxylase With Bound 7,8-Dihydro-L-Biopterin
Length = 307
Score = 25.8 bits (55), Expect = 9.8
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 21 NLVEWYDFYAYAFLAPYFAKE--FTHTNDPTLALISAFLVFMLGFFMRPLGSL 71
+L + + Y Y + P K F N P L +S FL GF +RP+ L
Sbjct: 79 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGL 131
>pdb|1J8T|A Chain A, Catalytic Domain Of Human Phenylalanine Hydroxylase Fe(Ii)
pdb|1J8U|A Chain A, Catalytic Domain Of Human Phenylalanine Hydroxylase Fe(Ii)
In Complex With Tetrahydrobiopterin
pdb|1LRM|A Chain A, Crystal Structure Of Binary Complex Of The Catalytic
Domain Of Human Phenylalanine Hydroxylase With
Dihydrobiopterin (Bh2)
Length = 325
Score = 25.8 bits (55), Expect = 9.8
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 21 NLVEWYDFYAYAFLAPYFAKE--FTHTNDPTLALISAFLVFMLGFFMRPLGSL 71
+L + + Y Y + P K F N P L +S FL GF +RP+ L
Sbjct: 94 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGL 146
>pdb|3PAH| Human Phenylalanine Hydroxylase Catalytic Domain Dimer With Bound
Adrenaline Inhibitor
pdb|4PAH| Human Phenylalanine Hydroxylase Catalytic Domain Dimer With Bound
Nor-Adrenaline Inhibitor
pdb|1PAH| Human Phenylalanine Hydroxylase Dimer, Residues 117 - 424
pdb|5PAH| Human Phenylalanine Hydroxylase Catalytic Domain Dimer With Bound
Dopamine Inhibitor
pdb|6PAH| Human Phenylalanine Hydroxylase Catalytic Domain Dimer With Bound
L-Dopa (3,4-Dihydroxyphenylalanine) Inhibitor
Length = 308
Score = 25.8 bits (55), Expect = 9.8
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 21 NLVEWYDFYAYAFLAPYFAKE--FTHTNDPTLALISAFLVFMLGFFMRPLGSL 71
+L + + Y Y + P K F N P L +S FL GF +RP+ L
Sbjct: 80 SLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGL 132
>pdb|1GVT|A Chain A, Endothiapepsin Complex With Cp-80,794
pdb|1GVU|A Chain A, Endothiapepsin Complex With H189
pdb|1GVV|A Chain A, Five Atomic Resolution Structures Of Endothiapepsin
Inhibitor Complexes; Implications For The Aspartic
Proteinase Mechanism
pdb|1GVW|A Chain A, Endothiapepsin Complex With Pd-130,328
pdb|1GVX|A Chain A, Endothiapepsin Complexed With H256
Length = 329
Score = 25.8 bits (55), Expect = 9.8
Identities = 12/33 (36%), Positives = 17/33 (51%)
Query: 376 IANALFGGSASYVALEFKQHGFEWGFVGYVMFS 408
I + GS +Y A+ KQ +EW GY + S
Sbjct: 173 IDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGS 205
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
Posted date: Dec 20, 2002 11:08 AM
Number of letters in database: 2,899,336
Number of sequences in database: 13,198
Lambda K H
0.328 0.143 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,172,278
Number of Sequences: 13198
Number of extensions: 82003
Number of successful extensions: 202
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 199
Number of HSP's gapped (non-prelim): 7
length of query: 426
length of database: 2,899,336
effective HSP length: 91
effective length of query: 335
effective length of database: 1,698,318
effective search space: 568936530
effective search space used: 568936530
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)