BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15645873|ref|NP_208051.1| conserved hypothetical
protein [Helicobacter pylori 26695]
         (205 letters)

Database: /var/www/html/HP/blast_new/blast/db/pdbaa
           13,198 sequences; 2,899,336 total letters

Searching...........................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pdb|1ICI|A  Chain A, Crystal Structure Of A Sir2 Homolog-Nad...   115  5e-27
pdb|1MA3|A  Chain A, Structure Of A Sir2 Enzyme Bound To An ...    99  3e-22
pdb|1J8F|C  Chain C, Human Sirt2 Histone Deacetylase               45  8e-06
pdb|1J8F|A  Chain A, Human Sirt2 Histone Deacetylase >gi|158...    45  8e-06
pdb|1EHY|A  Chain A, X-Ray Structure Of The Epoxide Hydrolas...    29  0.44
pdb|1C0N|A  Chain A, Csdb Protein, Nifs Homologue                  27  1.7
pdb|1JF9|A  Chain A, Crystal Structure Of Selenocysteine Lyase     27  2.2
pdb|1KMJ|A  Chain A, E. Coli NifsCSDB PROTEIN AT 2.0A WITH T...    27  2.2
pdb|1GRI|A  Chain A, Grb2 >gi|1421090|pdb|1GRI|B Chain B, Grb2     26  3.7
pdb|1J77|A  Chain A, Crystal Structure Of Gram-Negative Bact...    26  3.7
pdb|1AOZ|A  Chain A, Ascorbate Oxidase (E.C.1.10.3.3) >gi|44...    25  4.9
pdb|1II6|A  Chain A, Crystal Structure Of The Mitotic Kinesi...    25  4.9
pdb|1F3M|A  Chain A, Crystal Structure Of Human SerineTHREON...    25  8.3
>pdb|1ICI|A Chain A, Crystal Structure Of A Sir2 Homolog-Nad Complex
 pdb|1ICI|B Chain B, Crystal Structure Of A Sir2 Homolog-Nad Complex
          Length = 256

 Score =  115 bits (287), Expect = 5e-27
 Identities = 71/152 (46%), Positives = 96/152 (62%), Gaps = 7/152 (4%)

Query: 11  EVASPYGWKKNPQKVLDFYNQRRRQLFEVYPNKAHKALAELEKHYQVN-IITQNVDDLHE 69
           E+A+P  + K+P+KV  +Y  R  ++F   PNKAH+A AELE+   +  +ITQNVDDLHE
Sbjct: 57  ELANPQAFAKDPEKVWKWYAWRMEKVFNAQPNKAHQAFAELERLGVLKCLITQNVDDLHE 116

Query: 70  RAGSSRILHLHGELLSVRSEKDPNLVYRWEKDLNLGDLAK-DK--SQLRPDIVWFGEAVP 126
           RAGS  ++HLHG L  VR     N  +  E    +  L K DK  S LRP +VWFGE +P
Sbjct: 117 RAGSRNVIHLHGSLRVVRCTSCNN-SFEVESAPKIPPLPKCDKCGSLLRPGVVWFGEMLP 175

Query: 127 --LLKEAISLVKQAHLLIIIGTSLQVYPAASL 156
             +L  A+  V++A ++I+ GTS  V PAASL
Sbjct: 176 PDVLDRAMREVERADVIIVAGTSAVVQPAASL 207
>pdb|1MA3|A Chain A, Structure Of A Sir2 Enzyme Bound To An Acetylated P53
           Peptide
          Length = 253

 Score = 99.4 bits (246), Expect = 3e-22
 Identities = 72/207 (34%), Positives = 115/207 (54%), Gaps = 18/207 (8%)

Query: 7   HDIMEVASPYGWKKNPQKVLDFYNQRRRQLFEVYPNKAHKALAELEKHYQVN-IITQNVD 65
           +D  EVAS  G+K+NP+   +F  + + +LF   PN AH A+AELE+   V  +ITQN+D
Sbjct: 45  YDPEEVASISGFKRNPRAFWEFSMEMKDKLF-AEPNPAHYAIAELERMGIVKAVITQNID 103

Query: 66  DLHERAGSSRILHLHGELLSVRSEKDPNLVYRWE---KDLNLGDLAKDKS----QLRPDI 118
            LH+RAGS R+L LHG +  +    D +  Y W    +D N G++ + +      ++P +
Sbjct: 104 MLHQRAGSRRVLELHGSMDKLDC-LDCHETYDWSEFVEDFNKGEIPRCRKCGSYYVKPRV 162

Query: 119 VWFGEAVP--LLKEAISLVKQAHLLIIIGTSLQVYPAASL-YTHAHKDALIYYIDPKAKN 175
           V FGE +P   L EAI   K     +++G+SL VYPAA L Y      A +  ++ +   
Sbjct: 163 VLFGEPLPQRTLFEAIEEAKHCDAFMVVGSSLVVYPAAELPYIAKKAGAKMIIVNAEPTM 222

Query: 176 AHLPQNVQCINESAVHAMQDLMPKLIE 202
           A    +V+ I ++      +++PK++E
Sbjct: 223 ADPIFDVKIIGKAG-----EVLPKIVE 244
>pdb|1J8F|C Chain C, Human Sirt2 Histone Deacetylase
          Length = 323

 Score = 44.7 bits (104), Expect = 8e-06
 Identities = 39/140 (27%), Positives = 64/140 (44%), Gaps = 17/140 (12%)

Query: 38  EVYPNKAHKALAEL------EKHYQVNIITQNVDDLHERAGSSR--ILHLHGELLS---V 86
           E+YP +    +         +K   +   TQN+D L   AG  +  ++  HG   +   V
Sbjct: 104 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 163

Query: 87  RSEKDPNLVYRWEKDLNLGDLAKD----KSQLRPDIVWFGEAVP--LLKEAISLVKQAHL 140
            +         W K+    ++       +S ++PDIV+FGE++P        S   +  L
Sbjct: 164 SASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDL 223

Query: 141 LIIIGTSLQVYPAASLYTHA 160
           L+++GTSLQV P ASL + A
Sbjct: 224 LLVMGTSLQVQPFASLISKA 243
>pdb|1J8F|A Chain A, Human Sirt2 Histone Deacetylase
 pdb|1J8F|B Chain B, Human Sirt2 Histone Deacetylase
          Length = 323

 Score = 44.7 bits (104), Expect = 8e-06
 Identities = 39/140 (27%), Positives = 64/140 (44%), Gaps = 17/140 (12%)

Query: 38  EVYPNKAHKALAEL------EKHYQVNIITQNVDDLHERAGSSR--ILHLHGELLS---V 86
           E+YP +    +         +K   +   TQN+D L   AG  +  ++  HG   +   V
Sbjct: 104 ELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 163

Query: 87  RSEKDPNLVYRWEKDLNLGDLAKD----KSQLRPDIVWFGEAVP--LLKEAISLVKQAHL 140
            +         W K+    ++       +S ++PDIV+FGE++P        S   +  L
Sbjct: 164 SASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDL 223

Query: 141 LIIIGTSLQVYPAASLYTHA 160
           L+++GTSLQV P ASL + A
Sbjct: 224 LLVMGTSLQVQPFASLISKA 243
>pdb|1EHY|A Chain A, X-Ray Structure Of The Epoxide Hydrolase From
           Agrobacterium Radiobacter Ad1
 pdb|1EHY|B Chain B, X-Ray Structure Of The Epoxide Hydrolase From
           Agrobacterium Radiobacter Ad1
 pdb|1EHY|D Chain D, X-Ray Structure Of The Epoxide Hydrolase From
           Agrobacterium Radiobacter Ad1
 pdb|1EHY|C Chain C, X-Ray Structure Of The Epoxide Hydrolase From
           Agrobacterium Radiobacter Ad1
          Length = 294

 Score = 28.9 bits (63), Expect = 0.44
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 12/72 (16%)

Query: 53  KHYQVNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNLVYRWEKDLNLGDLAKDKS 112
           KHY+V +    +  + E AG + +L LHG          P   + W K +  G LA+   
Sbjct: 10  KHYEVQLPDVKIHYVREGAGPTLLL-LHGW---------PGFWWEWSKVI--GPLAEHYD 57

Query: 113 QLRPDIVWFGEA 124
            + PD+  FG++
Sbjct: 58  VIVPDLRGFGDS 69
>pdb|1C0N|A Chain A, Csdb Protein, Nifs Homologue
          Length = 406

 Score = 26.9 bits (58), Expect = 1.7
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 114 LRPDIVWFGEAVPLLKEAIS-LVKQAHLLIIIGTSLQVYPAASLYTHAHKDALIYYIDPK 172
           L PD     E +P L +A + L+   H+  ++GT     P A + T AH+      +D  
Sbjct: 146 LNPDGTLQLETLPTLFDAATRLLAITHVSNVLGTE---NPLAEMITLAHQHGAKVLVDGA 202

Query: 173 AKNAHLPQNVQCIN 186
               H P +VQ ++
Sbjct: 203 QAVMHHPVDVQALD 216
>pdb|1JF9|A Chain A, Crystal Structure Of Selenocysteine Lyase
          Length = 408

 Score = 26.6 bits (57), Expect = 2.2
 Identities = 21/74 (28%), Positives = 32/74 (42%), Gaps = 4/74 (5%)

Query: 114 LRPDIVWFGEAVP-LLKEAISLVKQAHLLIIIGTSLQVYPAASLYTHAHKDALIYYIDPK 172
           L PD     E +P L  E   L+   H+  ++GT     P A + T AH+      +D  
Sbjct: 148 LNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTE---NPLAEMITLAHQHGAKVLVDGA 204

Query: 173 AKNAHLPQNVQCIN 186
               H P +VQ ++
Sbjct: 205 QAVMHHPVDVQALD 218
>pdb|1KMJ|A Chain A, E. Coli NifsCSDB PROTEIN AT 2.0A WITH THE CYSTEINE
           Persulfide Intermediate (Residue Css).
 pdb|1KMK|A Chain A, E. Coli NifsCSDB PROTEIN AT 2.20A WITH THE CYSTEINE
           Perselenide Intermediate (Residue Csz)
          Length = 406

 Score = 26.6 bits (57), Expect = 2.2
 Identities = 21/74 (28%), Positives = 32/74 (42%), Gaps = 4/74 (5%)

Query: 114 LRPDIVWFGEAVP-LLKEAISLVKQAHLLIIIGTSLQVYPAASLYTHAHKDALIYYIDPK 172
           L PD     E +P L  E   L+   H+  ++GT     P A + T AH+      +D  
Sbjct: 146 LNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTE---NPLAEMITLAHQHGAKVLVDGA 202

Query: 173 AKNAHLPQNVQCIN 186
               H P +VQ ++
Sbjct: 203 QAVMHHPVDVQALD 216
>pdb|1GRI|A Chain A, Grb2
 pdb|1GRI|B Chain B, Grb2
          Length = 217

 Score = 25.8 bits (55), Expect = 3.7
 Identities = 17/59 (28%), Positives = 29/59 (48%), Gaps = 1/59 (1%)

Query: 81  GELLSVRSEKDPNLVYRWEKDLNLGDLAKDKSQLRPDIVWFGEAVPLLKEAISLVKQAH 139
           G++L V +E+     Y+ E +   G + K+  +++P   WF   +P  K    L KQ H
Sbjct: 22  GDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPH-PWFFGKIPRAKAEEMLSKQRH 79
>pdb|1J77|A Chain A, Crystal Structure Of Gram-Negative Bacterial Heme
          Oxygenase Complexed With Heme
          Length = 209

 Score = 25.8 bits (55), Expect = 3.7
 Identities = 16/56 (28%), Positives = 31/56 (54%), Gaps = 1/56 (1%)

Query: 15 PYGWKKNPQKVLDFYNQRRRQLFEVYPN-KAHKALAELEKHYQVNIITQNVDDLHE 69
          P+  K+N  K L   +   + +  +Y + + +KA+ ELE   + + +TQ++ DL E
Sbjct: 35 PFVSKENYIKFLKLQSVFHKAVDHIYKDAELNKAIPELEYMARYDAVTQDLKDLGE 90
>pdb|1AOZ|A Chain A, Ascorbate Oxidase (E.C.1.10.3.3)
 pdb|1AOZ|B Chain B, Ascorbate Oxidase (E.C.1.10.3.3)
 pdb|1ASO|A Chain A, Ascorbate Oxidase (Reduced Form) (E.C.1.10.3.3)
 pdb|1ASO|B Chain B, Ascorbate Oxidase (Reduced Form) (E.C.1.10.3.3)
 pdb|1ASQ|A Chain A, Ascorbate Oxidase (Azide Form) (E.C.1.10.3.3)
 pdb|1ASQ|B Chain B, Ascorbate Oxidase (Azide Form) (E.C.1.10.3.3)
 pdb|1ASP|A Chain A, Ascorbate Oxidase (Peroxide Form) (E.C.1.10.3.3)
 pdb|1ASP|B Chain B, Ascorbate Oxidase (Peroxide Form) (E.C.1.10.3.3)
          Length = 552

 Score = 25.4 bits (54), Expect = 4.9
 Identities = 15/48 (31%), Positives = 20/48 (41%)

Query: 57  VNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNLVYRWEKDLNL 104
           V++I QN + + E    +   HLHG    V    D       E  LNL
Sbjct: 427 VDVILQNANMMKENLSETHPWHLHGHDFWVLGYGDGKFSAEEESSLNL 474
>pdb|1II6|A Chain A, Crystal Structure Of The Mitotic Kinesin Eg5 In Complex
           With Mg-Adp.
 pdb|1II6|B Chain B, Crystal Structure Of The Mitotic Kinesin Eg5 In Complex
           With Mg-Adp
          Length = 368

 Score = 25.4 bits (54), Expect = 4.9
 Identities = 10/34 (29%), Positives = 18/34 (52%)

Query: 81  GELLSVRSEKDPNLVYRWEKDLNLGDLAKDKSQL 114
           G+  ++  E+ PN  Y WE+D   G + +   Q+
Sbjct: 110 GKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQI 143
>pdb|1F3M|A Chain A, Crystal Structure Of Human SerineTHREONINE KINASE PAK1
 pdb|1F3M|B Chain B, Crystal Structure Of Human SerineTHREONINE KINASE PAK1
          Length = 80

 Score = 24.6 bits (52), Expect = 8.3
 Identities = 13/32 (40%), Positives = 18/32 (55%), Gaps = 3/32 (9%)

Query: 19 KKNPQKVLD---FYNQRRRQLFEVYPNKAHKA 47
          KKNPQ VLD   FYN ++    + Y +   K+
Sbjct: 49 KKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKS 80
  Database: /var/www/html/HP/blast_new/blast/db/pdbaa
    Posted date:  Dec 20, 2002 11:08 AM
  Number of letters in database: 2,899,336
  Number of sequences in database:  13,198
  
Lambda     K      H
   0.319    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,187,076
Number of Sequences: 13198
Number of extensions: 45693
Number of successful extensions: 100
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 86
Number of HSP's gapped (non-prelim): 13
length of query: 205
length of database: 2,899,336
effective HSP length: 84
effective length of query: 121
effective length of database: 1,790,704
effective search space: 216675184
effective search space used: 216675184
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 52 (24.6 bits)