BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15646043|ref|NP_208225.1| formyltetrahydrofolate
hydrolase (purU) [Helicobacter pylori 26695]
(293 letters)
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
13,198 sequences; 2,899,336 total letters
Searching...........................done
Score E
Sequences producing significant alignments: (bits) Value
pdb|1C3E|A Chain A, New Insights Into Inhibitor Design From... 80 3e-16
pdb|1CDD|A Chain A, Phosphoribosylglycinamide Formyltransfe... 80 3e-16
pdb|1JKX|A Chain A, Unexpected Formation Of An Epoxide-Deri... 80 3e-16
pdb|3GAR| A Ph-Dependent Stablization Of An Active Site L... 79 8e-16
pdb|2FMT|A Chain A, Methionyl-Trnafmet Formyltransferase Co... 42 1e-04
pdb|1BMO|A Chain A, Bm-40, FsEC DOMAIN PAIR >gi|2624794|pdb... 28 1.6
pdb|1SRA| Extracellular Matrix Protein Mol_id: 1; Molecul... 28 1.6
pdb|1CQX|A Chain A, Crystal Structure Of The Flavohemoglobi... 26 4.7
pdb|1XGS|A Chain A, Methionine Aminopeptidase From Hyperthe... 26 6.2
pdb|1DJ0|A Chain A, The Crystal Structure Of E. Coli Pseudo... 25 8.1
>pdb|1C3E|A Chain A, New Insights Into Inhibitor Design From The Crystal
Structure And Nmr Studies Of E. Coli Gar Transformylate
In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid.
pdb|1C3E|B Chain B, New Insights Into Inhibitor Design From The Crystal
Structure And Nmr Studies Of E. Coli Gar Transformylate
In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid
Length = 209
Score = 80.1 bits (196), Expect = 3e-16
Identities = 43/125 (34%), Positives = 70/125 (55%), Gaps = 3/125 (2%)
Query: 167 ELKHKV---SADLLVLAKYMRILSHDFTKRYENQILNIHHSFLPAFIGANPYQQAFERGV 223
EL H++ + D++VLA +MRILS F Y ++LNIH S LP + G + ++QA E G
Sbjct: 70 ELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGD 129
Query: 224 KVIGATAHFVNESLDAGPIIIQDTLPINHNYSVEKMRLAGKDIEKLVLARALKLVLEDRV 283
+ G + HFV + LD GP+I+Q +P+ S + + + E + + + R+
Sbjct: 130 EEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRL 189
Query: 284 FVHEN 288
+HEN
Sbjct: 190 KMHEN 194
>pdb|1CDD|A Chain A, Phosphoribosylglycinamide Formyltransferase (E.C.2.1.2.2)
(5'-Phosphoribosylglycinamide Transformylase)
pdb|1CDD|B Chain B, Phosphoribosylglycinamide Formyltransferase (E.C.2.1.2.2)
(5'-Phosphoribosylglycinamide Transformylase)
Length = 212
Score = 80.1 bits (196), Expect = 3e-16
Identities = 43/125 (34%), Positives = 70/125 (55%), Gaps = 3/125 (2%)
Query: 167 ELKHKV---SADLLVLAKYMRILSHDFTKRYENQILNIHHSFLPAFIGANPYQQAFERGV 223
EL H++ + D++VLA +MRILS F Y ++LNIH S LP + G + ++QA E G
Sbjct: 70 ELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGD 129
Query: 224 KVIGATAHFVNESLDAGPIIIQDTLPINHNYSVEKMRLAGKDIEKLVLARALKLVLEDRV 283
+ G + HFV + LD GP+I+Q +P+ S + + + E + + + R+
Sbjct: 130 EEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRL 189
Query: 284 FVHEN 288
+HEN
Sbjct: 190 KMHEN 194
>pdb|1JKX|A Chain A, Unexpected Formation Of An Epoxide-Derived Multisubstrate
Adduct Inhibitor On The Active Site Of Gar
Transformylase
pdb|1JKX|B Chain B, Unexpected Formation Of An Epoxide-Derived Multisubstrate
Adduct Inhibitor On The Active Site Of Gar
Transformylase
pdb|1JKX|C Chain C, Unexpected Formation Of An Epoxide-Derived Multisubstrate
Adduct Inhibitor On The Active Site Of Gar
Transformylase
pdb|1JKX|D Chain D, Unexpected Formation Of An Epoxide-Derived Multisubstrate
Adduct Inhibitor On The Active Site Of Gar
Transformylase
pdb|1C2T|A Chain A, New Insights Into Inhibitor Design From The Crystal
Structure And Nmr Studies Of E. Coli Gar Transformylase
In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid.
pdb|1C2T|B Chain B, New Insights Into Inhibitor Design From The Crystal
Structure And Nmr Studies Of E. Coli Gar Transformylase
In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid.
pdb|1CDE| Phosphoribosylglycinamide Formyltransferase (E.C.2.1.2.2)
(5'-Phosphoribosylglycinamide Transformylase) Complex
With Glycinamide Ribonucleotide And The Inhibitor
5-Deaza-5,6,7,8-Tetrahydrofolate
pdb|1GAR|A Chain A, Glycinamide Ribonucleotide Transformylase
(10-Formyltetrahydrofolate-5'-Phosphoribosylglycinamide
Formyltransferase) (E.C.2.1.2.2) Complexed With
Burroughs-Wellcome Inhibitor 1476u89
pdb|1GAR|B Chain B, Glycinamide Ribonucleotide Transformylase
(10-Formyltetrahydrofolate-5'-Phosphoribosylglycinamide
Formyltransferase) (E.C.2.1.2.2) Complexed With
Burroughs-Wellcome Inhibitor 1476u89
pdb|1GRC|A Chain A, Glycinamide Ribonucleotide Transformylase (E.C.2.1.2.2)
pdb|1GRC|B Chain B, Glycinamide Ribonucleotide Transformylase (E.C.2.1.2.2)
Length = 212
Score = 80.1 bits (196), Expect = 3e-16
Identities = 43/125 (34%), Positives = 70/125 (55%), Gaps = 3/125 (2%)
Query: 167 ELKHKV---SADLLVLAKYMRILSHDFTKRYENQILNIHHSFLPAFIGANPYQQAFERGV 223
EL H++ + D++VLA +MRILS F Y ++LNIH S LP + G + ++QA E G
Sbjct: 70 ELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGD 129
Query: 224 KVIGATAHFVNESLDAGPIIIQDTLPINHNYSVEKMRLAGKDIEKLVLARALKLVLEDRV 283
+ G + HFV + LD GP+I+Q +P+ S + + + E + + + R+
Sbjct: 130 EEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRL 189
Query: 284 FVHEN 288
+HEN
Sbjct: 190 KMHEN 194
>pdb|3GAR| A Ph-Dependent Stablization Of An Active Site Loop Observed From
Low And High Ph Crystal Structures Of Mutant Monomeric
Glycinamide Ribonucleotide Transformylase
pdb|2GAR| A Ph-Dependent Stablization Of An Active Site Loop Observed From
Low And High Ph Crystal Structures Of Mutant Monomeric
Glycinamide Ribonucleotide Transformylase
Length = 212
Score = 78.6 bits (192), Expect = 8e-16
Identities = 40/114 (35%), Positives = 64/114 (56%)
Query: 175 DLLVLAKYMRILSHDFTKRYENQILNIHHSFLPAFIGANPYQQAFERGVKVIGATAHFVN 234
D++VLA +MRILS F Y ++LNIH S LP + G + ++QA E G + G + HFV
Sbjct: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140
Query: 235 ESLDAGPIIIQDTLPINHNYSVEKMRLAGKDIEKLVLARALKLVLEDRVFVHEN 288
+ LD GP+I+Q +P+ S + + + E + + + R+ +HEN
Sbjct: 141 DELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHEN 194
>pdb|2FMT|A Chain A, Methionyl-Trnafmet Formyltransferase Complexed With
Formyl-Methionyl-Trnafmet
pdb|2FMT|B Chain B, Methionyl-Trnafmet Formyltransferase Complexed With
Formyl-Methionyl-Trnafmet
pdb|1FMT|A Chain A, Methionyl-Trnafmet Formyltransferase From Escherichia Coli
pdb|1FMT|B Chain B, Methionyl-Trnafmet Formyltransferase From Escherichia Coli
Length = 314
Score = 41.6 bits (96), Expect = 1e-04
Identities = 25/87 (28%), Positives = 44/87 (49%)
Query: 164 KNLELKHKVSADLLVLAKYMRILSHDFTKRYENQILNIHHSFLPAFIGANPYQQAFERGV 223
+N +L ++ AD++V+ Y IL + +N+H S LP + GA P Q++ G
Sbjct: 72 ENQQLVAELQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGD 131
Query: 224 KVIGATAHFVNESLDAGPIIIQDTLPI 250
G T ++ LD G ++ + + PI
Sbjct: 132 AETGVTIMQMDVGLDTGDMLYKLSCPI 158
>pdb|1BMO|A Chain A, Bm-40, FsEC DOMAIN PAIR
pdb|1BMO|B Chain B, Bm-40, FsEC DOMAIN PAIR
Length = 233
Score = 27.7 bits (60), Expect = 1.6
Identities = 17/56 (30%), Positives = 27/56 (47%), Gaps = 4/56 (7%)
Query: 150 DNQVLHEKEVLEIIKNLELKHKVSADLLVLAKYMRILSHDFTKRYENQILNIHHSF 205
DN +L EK+ L + K E + ++ A + +L+ DF K Y I +H F
Sbjct: 114 DNNLLTEKQKLRVKKIHENEKRLEAG----DHPVELLARDFEKNYNMYIFPVHWQF 165
>pdb|1SRA| Extracellular Matrix Protein Mol_id: 1; Molecule: Sparc; Chain:
Null; Fragment: Carboxy-Terminal Domain (Residues 136 -
286); Synonym: Bm-40, Osteonectin; Engineered: Yes;
Heterogen: 2 Ca 2+ Ions, One Unidentified Metal Ion
Modeled As Ca 2+; Other_details: Crystallized From 0.7 M
K, Na-Tartrate, Ph 7.5 + 2 Mm Cacl2
Length = 151
Score = 27.7 bits (60), Expect = 1.6
Identities = 17/56 (30%), Positives = 27/56 (47%), Gaps = 4/56 (7%)
Query: 150 DNQVLHEKEVLEIIKNLELKHKVSADLLVLAKYMRILSHDFTKRYENQILNIHHSF 205
DN +L EK+ L + K E + ++ A + +L+ DF K Y I +H F
Sbjct: 32 DNNLLTEKQKLRVKKIHENEKRLEAG----DHPVELLARDFEKNYNMYIFPVHWQF 83
>pdb|1CQX|A Chain A, Crystal Structure Of The Flavohemoglobin From
Alcaligenes Eutrophus At 1.75 A Resolution
pdb|1CQX|B Chain B, Crystal Structure Of The Flavohemoglobin From
Alcaligenes Eutrophus At 1.75 A Resolution
Length = 403
Score = 26.2 bits (56), Expect = 4.7
Identities = 17/71 (23%), Positives = 33/71 (45%), Gaps = 6/71 (8%)
Query: 13 SKGLVSTISTTIANKGYNIVKNDEFVDPLKQRFFMRLKIQKEIKPLNTEIKEQEEQSLKT 72
+K +V + +A GY+I+K QR F K + + + + Q++Q+L
Sbjct: 6 TKDIVKATAPVLAEHGYDIIK------CFYQRMFEAHPELKNVFNMAHQEQGQQQQALAR 59
Query: 73 ALFKALENFNE 83
A++ EN +
Sbjct: 60 AVYAYAENIED 70
>pdb|1XGS|A Chain A, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGS|B Chain B, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGM|A Chain A, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGM|B Chain B, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGN|A Chain A, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGN|B Chain B, Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
pdb|1XGO| Methionine Aminopeptidase From Hyperthermophile Pyrococcus
Furiosus
Length = 295
Score = 25.8 bits (55), Expect = 6.2
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 127 ISNHEILR-PLVEKFDIPYFYAPCDNQVLHEKEVLEI 162
+S H+I R L IP Y P DN VL E +V I
Sbjct: 150 LSGHKIERYKLHAGISIPNIYRPHDNYVLKEGDVFAI 186
>pdb|1DJ0|A Chain A, The Crystal Structure Of E. Coli Pseudouridine Synthase I
At 1.5 Angstrom Resolution
pdb|1DJ0|B Chain B, The Crystal Structure Of E. Coli Pseudouridine Synthase I
At 1.5 Angstrom Resolution
Length = 264
Score = 25.4 bits (54), Expect = 8.1
Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 126 VISNHEILRPLVEKFDIPYFYAPCDNQVLH 155
+I NH LRP V + +FY P D + +H
Sbjct: 115 IIYNHR-LRPAVLSKGVTHFYEPLDAERMH 143
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
Posted date: Dec 20, 2002 11:08 AM
Number of letters in database: 2,899,336
Number of sequences in database: 13,198
Lambda K H
0.322 0.140 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,514,225
Number of Sequences: 13198
Number of extensions: 59819
Number of successful extensions: 161
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 156
Number of HSP's gapped (non-prelim): 10
length of query: 293
length of database: 2,899,336
effective HSP length: 87
effective length of query: 206
effective length of database: 1,751,110
effective search space: 360728660
effective search space used: 360728660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 54 (25.4 bits)