BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15646067|ref|NP_208249.1| thioredoxin [Helicobacter
pylori 26695]
         (104 letters)

Database: /var/www/html/HP/blast_new/blast/db/pdbaa
           13,198 sequences; 2,899,336 total letters

Searching...........................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pdb|1FB0|A  Chain A, Crystal Structure Of Thioredoxin M From...    63  4e-12
pdb|1GL8|A  Chain A, Solution Structure Of Thioredoxin M Fro...    63  4e-12
pdb|1XOB|A  Chain A, Thioredoxin (Reduced Dithio Form), Nmr,...    60  4e-11
pdb|1EP7|A  Chain A, Crystal Structure Of Wt Thioredoxin H F...    60  4e-11
pdb|1XOB|    Thioredoxin (Reduced Dithio Form), Nmr, 20 Stru...    60  4e-11
pdb|2TIR|    Thioredoxin Mutant With Lys 36 Replaced By Glu ...    59  6e-11
pdb|1TXX|A  Chain A, Active-Site Variant Of E.Coli Thioredoxin     59  8e-11
pdb|1EP8|A  Chain A, Crystal Structure Of A Mutated Thioredo...    59  8e-11
pdb|1M7T|A  Chain A, Solution Structure And Dynamics Of The ...    59  1e-10
pdb|1DBY|A  Chain A, Nmr Structures Of Chloroplast Thioredox...    58  2e-10
pdb|1F6M|C  Chain C, Crystal Structure Of A Complex Between ...    56  5e-10
pdb|1QUW|A  Chain A, Solution Structure Of The Thioredoxin F...    56  5e-10
pdb|1THO|    Thioredoxin Mutant With Arg Inserted Between Gl...    55  9e-10
pdb|1ERV|    Human Thioredoxin Mutant With Cys 73 Replaced B...    54  2e-09
pdb|1TRS|    Thioredoxin Mutant With Cys 62 Replaced By Ala,...    54  3e-09
pdb|1SRX|    Three-Dimensional Structure Of Escherichia Coli...    54  3e-09
pdb|1ERT|    Human Thioredoxin (Reduced Form) >gi|2982059|pd...    53  4e-09
pdb|3TRX|    Thioredoxin (Reduced Form) >gi|231098|pdb|4TRX|...    52  8e-09
pdb|1AIU|    Human Thioredoxin (D60n Mutant, Reduced Form)         51  2e-08
pdb|1CQG|A  Chain A, High Resolution Solution Nmr Structure ...    50  3e-08
pdb|1ERW|    Human Thioredoxin Double Mutant With Cys 32 Rep...    45  9e-07
pdb|1MEK|    Human Protein Disulfide Isomerase, Nmr, 40 Stru...    45  9e-07
pdb|1F9M|A  Chain A, Crystal Structure Of Thioredoxin F From...    42  1e-05
pdb|1FAA|A  Chain A, Crystal Structure Of Thioredoxin F From...    42  1e-05
pdb|1THX|    Thioredoxin-2                                         41  2e-05
pdb|1FG4|A  Chain A, Structure Of Tryparedoxin Ii >gi|142783...    34  0.003
pdb|1QGV|A  Chain A, Human Spliceosomal Protein U5-15kd            33  0.005
pdb|1EZK|A  Chain A, Crystal Structure Of Recombinant Trypar...    30  0.031
pdb|1EWX|A  Chain A, Crystal Structure Of Native Tryparedoxi...    30  0.031
pdb|1QK8|A  Chain A, Tryparedoxin-I From Crithidia Fasciculata     30  0.031
pdb|1I5G|A  Chain A, Tryparedoxin Ii Complexed With Glutathi...    30  0.040
pdb|1JFU|B  Chain B, Crystal Structure Of The Soluble Domain...    30  0.053
pdb|1KNG|A  Chain A, Crystal Structure Of Ccmg Reducing Oxid...    28  0.15
pdb|1EI3|A  Chain A, Crystal Structure Of Native Chicken Fib...    25  0.99
pdb|1JDI|A  Chain A, Crystal Structure Of L-Ribulose-5-Phosp...    24  2.9
pdb|2ALR|    Aldehyde Reductase                                    23  3.8
pdb|1BED|    Structure Of Disulfide Oxidoreductase                 23  3.8
pdb|1BG1|A  Chain A, Three-Dimensional Structure Of The Stat...    23  4.9
pdb|1QFX|B  Chain B, Ph 2.5 Acid Phosphatase From Aspergillu...    23  4.9
pdb|1HUS|    Ribosomal Protein S7                                  23  4.9
pdb|1MTZ|A  Chain A, Crystal Structure Of The Tricorn Intera...    23  6.4
pdb|1GZS|B  Chain B, Crystal Structure Of The Complex Betwee...    23  6.4
pdb|1CWN|    Crystal Structure Of Porcine Aldehyde Reductase...    23  6.4
pdb|1MT3|A  Chain A, Crystal Structure Of The Tricorn Intera...    23  6.4
pdb|1AE4|    Aldehyde Reductase Complexed With Cofactor And ...    23  6.4
pdb|1C9W|A  Chain A, Cho Reductase With Nadp+                      22  8.4
>pdb|1FB0|A Chain A, Crystal Structure Of Thioredoxin M From Spinach
           Chloroplast (Reduced Form)
 pdb|1FB6|A Chain A, Crystal Structure Of Thioredoxin M From Spinach
           Chloroplast (Oxidized Form)
 pdb|1FB6|B Chain B, Crystal Structure Of Thioredoxin M From Spinach
           Chloroplast (Oxidized Form)
 pdb|1FB0|B Chain B, Crystal Structure Of Thioredoxin M From Spinach
           Chloroplast (Reduced Form)
          Length = 105

 Score = 63.2 bits (152), Expect = 4e-12
 Identities = 29/86 (33%), Positives = 51/86 (58%), Gaps = 1/86 (1%)

Query: 19  VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
           V+V+  A WC  C+ I P+++ LAK Y GK+  +K++ DE+  +     IR IPT++F+K
Sbjct: 21  VMVDFWAPWCGPCKLIAPVIDELAKEYSGKIAVYKLNTDEAPGIATQYNIRSIPTVLFFK 80

Query: 79  NAKEVGERLVEPSSQKPIEDALKALL 104
           N  E  E ++    +  + D+++  L
Sbjct: 81  NG-ERKESIIGAVPKSTLTDSIEKYL 105
>pdb|1GL8|A Chain A, Solution Structure Of Thioredoxin M From Spinach, Oxidized
           Form
          Length = 104

 Score = 63.2 bits (152), Expect = 4e-12
 Identities = 29/86 (33%), Positives = 51/86 (58%), Gaps = 1/86 (1%)

Query: 19  VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
           V+V+  A WC  C+ I P+++ LAK Y GK+  +K++ DE+  +     IR IPT++F+K
Sbjct: 20  VMVDFWAPWCGPCKLIAPVIDELAKEYSGKIAVYKLNTDEAPGIATQYNIRSIPTVLFFK 79

Query: 79  NAKEVGERLVEPSSQKPIEDALKALL 104
           N  E  E ++    +  + D+++  L
Sbjct: 80  NG-ERKESIIGAVPKSTLTDSIEKYL 104
>pdb|1XOB|A Chain A, Thioredoxin (Reduced Dithio Form), Nmr, 20 Structures
 pdb|1XOA|   Thioredoxin (Oxidized Disulfide Form), Nmr, 20 Structures
          Length = 108

 Score = 60.1 bits (144), Expect = 4e-11
 Identities = 32/90 (35%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC  C+ I PI++ +A  Y+GK+   K++ D++       GIR IPTL
Sbjct: 19  ADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|1EP7|A Chain A, Crystal Structure Of Wt Thioredoxin H From Chlamydomonas
           Reinhardtii
 pdb|1EP7|B Chain B, Crystal Structure Of Wt Thioredoxin H From Chlamydomonas
           Reinhardtii
 pdb|1TOF|   Thioredoxin H (Oxidized Form), Nmr, 23 Structures
          Length = 112

 Score = 60.1 bits (144), Expect = 4e-11
 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 6/92 (6%)

Query: 13  KIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIP 72
           K  H+ +VV+  A+WC  C+ I P+ E L+  Y GKV F KV  D    + E+ GI  +P
Sbjct: 21  KEEHKPIVVDFTATWCGPCKMIAPLFETLSNDYAGKVIFLKVDVDAVAAVAEAAGITAMP 80

Query: 73  TLIFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           T   YK+  +  + LV  S     +D LKAL+
Sbjct: 81  TFHVYKDGVKADD-LVGAS-----QDKLKALV 106
>pdb|1XOB|   Thioredoxin (Reduced Dithio Form), Nmr, 20 Structures
 pdb|2TRX|A Chain A, Thioredoxin
 pdb|2TRX|B Chain B, Thioredoxin
 pdb|1T7P|B Chain B, T7 Dna Polymerase Complexed To Dna PrimerTEMPLATE,A
           Nucleoside Triphosphate, And Its Processivity Factor
           Thioredoxin
          Length = 108

 Score = 60.1 bits (144), Expect = 4e-11
 Identities = 32/90 (35%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC  C+ I PI++ +A  Y+GK+   K++ D++       GIR IPTL
Sbjct: 19  ADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|2TIR|   Thioredoxin Mutant With Lys 36 Replaced By Glu (K36e)
          Length = 108

 Score = 59.3 bits (142), Expect = 6e-11
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC  C  I PI++ +A  Y+GK+   K++ D++       GIR IPTL
Sbjct: 19  ADGAILVDFWAEWCGPCEMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|1TXX|A Chain A, Active-Site Variant Of E.Coli Thioredoxin
          Length = 108

 Score = 58.9 bits (141), Expect = 8e-11
 Identities = 32/90 (35%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC  C+ I PI++ +A  Y+GK+   K++ D++       GIR IPTL
Sbjct: 19  ADGAILVDFWAEWCVWCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|1EP8|A Chain A, Crystal Structure Of A Mutated Thioredoxin, D30a, From
           Chlamydomonas Reinhardtii
 pdb|1EP8|B Chain B, Crystal Structure Of A Mutated Thioredoxin, D30a, From
           Chlamydomonas Reinhardtii
          Length = 112

 Score = 58.9 bits (141), Expect = 8e-11
 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 6/92 (6%)

Query: 13  KIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIP 72
           K  H+ +VV   A+WC  C+ I P+ E L+  Y GKV F KV  D    + E+ GI  +P
Sbjct: 21  KEEHKPIVVAFTATWCGPCKMIAPLFETLSNDYAGKVIFLKVDVDAVAAVAEAAGITAMP 80

Query: 73  TLIFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           T   YK+  +  + LV  S     +D LKAL+
Sbjct: 81  TFHVYKDGVKADD-LVGAS-----QDKLKALV 106
>pdb|1M7T|A Chain A, Solution Structure And Dynamics Of The Human-Escherichia
           Coli Thioredoxin Chimera: Insights Into Thermodynamic
           Stability
          Length = 107

 Score = 58.5 bits (140), Expect = 1e-10
 Identities = 32/86 (37%), Positives = 50/86 (57%), Gaps = 2/86 (2%)

Query: 19  VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
           VVV+  A+WC  C+ I+P   +L++ Y   + F +V  D++QD+    GIR IPTL+ +K
Sbjct: 23  VVVDFSATWCGPCKMIKPFFHSLSEKYSNVI-FLEVDVDDAQDVAPKYGIRGIPTLLLFK 81

Query: 79  NAKEVGERLVEPSSQKPIEDALKALL 104
           N  EV    V   S+  +++ L A L
Sbjct: 82  NG-EVAATKVGALSKGQLKEFLDANL 106
>pdb|1DBY|A Chain A, Nmr Structures Of Chloroplast Thioredoxin M Ch2 From The
          Green Alga Chlamydomonas Reinhardtii
          Length = 107

 Score = 57.8 bits (138), Expect = 2e-10
 Identities = 25/64 (39%), Positives = 41/64 (64%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          V+V+  A WC  CR I P+++ +A  YK K++  K++ DES ++    GIR IPT++ +K
Sbjct: 22 VLVDFWAPWCGPCRIIAPVVDEIAGEYKDKLKCVKLNTDESPNVASEYGIRSIPTIMVFK 81

Query: 79 NAKE 82
            K+
Sbjct: 82 GGKK 85
>pdb|1F6M|C Chain C, Crystal Structure Of A Complex Between Thioredoxin
           Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
 pdb|1F6M|D Chain D, Crystal Structure Of A Complex Between Thioredoxin
           Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
 pdb|1F6M|G Chain G, Crystal Structure Of A Complex Between Thioredoxin
           Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
 pdb|1F6M|H Chain H, Crystal Structure Of A Complex Between Thioredoxin
           Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
          Length = 108

 Score = 56.2 bits (134), Expect = 5e-10
 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC   + I PI++ +A  Y+GK+   K++ D++       GIR IPTL
Sbjct: 19  ADGAILVDFWAEWCGPSKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|1QUW|A Chain A, Solution Structure Of The Thioredoxin From Bacillus
           Acidocaldarius
          Length = 105

 Score = 56.2 bits (134), Expect = 5e-10
 Identities = 28/86 (32%), Positives = 49/86 (56%), Gaps = 1/86 (1%)

Query: 19  VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
           V+V+  A+WC  CR + P++E  A+ +  KV   K++ DE+ +     GI  IPTLI +K
Sbjct: 20  VLVDFWAAWCGPCRMMAPVLEEFAEAHADKVTVAKLNVDENPETTSQFGIMSIPTLILFK 79

Query: 79  NAKEVGERLVEPSSQKPIEDALKALL 104
             + V ++L+    ++ +E  L  +L
Sbjct: 80  GGRPV-KQLIGYQPKEQLEAQLADVL 104
>pdb|1THO|   Thioredoxin Mutant With Arg Inserted Between Gly 33 And Pro 34
           (33r34)
          Length = 109

 Score = 55.5 bits (132), Expect = 9e-10
 Identities = 32/91 (35%), Positives = 51/91 (55%), Gaps = 2/91 (2%)

Query: 15  AHQAVVVNVGASWCP-DCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPT 73
           A  A++V+  A WC   C+ I PI++ +A  Y+GK+   K++ D++       GIR IPT
Sbjct: 19  ADGAILVDFWAEWCGRPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPT 78

Query: 74  LIFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           L+ +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLLFKNG-EVAATKVGALSKGQLKEFLDANL 108
>pdb|1ERV|   Human Thioredoxin Mutant With Cys 73 Replaced By Ser (Reduced
          Form)
          Length = 105

 Score = 54.3 bits (129), Expect = 2e-09
 Identities = 23/67 (34%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC  C+ I+P   +L++ Y   + F +V  D+ QD+     ++ +PT  F+K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSLSEKYSNVI-FLEVDVDDCQDVASECEVKSMPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1TRS|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced
          By Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a)
          (Oxidized) (Nmr, Minimized Average Structure)
 pdb|1TRU|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced
          By Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a)
          (Oxidized) (Nmr, 40 Structures)
 pdb|1TRV|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced
          By Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a)
          (Reduced) (Nmr, 40 Structures)
 pdb|1TRW|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced
          By Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a)
          (Reduced) (Nmr, Minimized Average Structure)
          Length = 105

 Score = 53.9 bits (128), Expect = 3e-09
 Identities = 23/67 (34%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC  C+ I+P   +L++ Y   + F +V  D++QD+     ++  PT  F+K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSLSEKYSNVI-FLEVDVDDAQDVASEAEVKATPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1SRX|   Three-Dimensional Structure Of Escherichia Coli Thioredoxin- S2 To
           2.8 Angstroms Resolution
          Length = 108

 Score = 53.5 bits (127), Expect = 3e-09
 Identities = 30/90 (33%), Positives = 49/90 (54%), Gaps = 1/90 (1%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A  A++V+  A WC  C+ I PI++ +A  Y+GK+   K++ D++         R IPTL
Sbjct: 19  ADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYIERGIPTL 78

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
           + +KN  EV    V   S+  +++ L A L
Sbjct: 79  LLFKNG-EVAATKVGALSKGQLKEFLDANL 107
>pdb|1ERT|   Human Thioredoxin (Reduced Form)
 pdb|1AUC|   Human Thioredoxin (Oxidized With Diamide)
 pdb|1ERU|   Human Thioredoxin (Oxidized Form)
          Length = 105

 Score = 53.1 bits (126), Expect = 4e-09
 Identities = 24/67 (35%), Positives = 40/67 (58%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC  C+ I+P   +L++ Y   V F +V  D+ QD+     ++ +PT  F+K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKCMPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|3TRX|   Thioredoxin (Reduced Form)
 pdb|4TRX|   Thioredoxin (Reduced Form)
          Length = 105

 Score = 52.4 bits (124), Expect = 8e-09
 Identities = 24/67 (35%), Positives = 39/67 (57%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC  C+ I+P   +L++ Y   V F +V  D+ QD+     ++  PT  F+K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKCTPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1AIU|   Human Thioredoxin (D60n Mutant, Reduced Form)
          Length = 105

 Score = 51.2 bits (121), Expect = 2e-08
 Identities = 23/67 (34%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC  C+ I+P   +L++ Y   V F +V  ++ QD+     ++ +PT  F+K
Sbjct: 23 VVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVNDCQDVASECEVKCMPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1CQG|A Chain A, High Resolution Solution Nmr Structure Of Mixed
          Disulfide Intermediate Between Human Thioredoxin (C35a,
          C62a, C69a, C73a) Mutant And A 13 Residue Peptide
          Comprising Its Target Site In Human Ref-1 (Residues 59
          - 71 Of The P50 Subunit Of Nfkb), Nmr, 31 Structures
 pdb|1CQH|A Chain A, High Resolution Solution Nmr Structure Of Mixed
          Disulfide Intermediate Between Human Thioredoxin (C35a,
          C62a, C69a, C73a) Mutant And A 13 Residue Peptide
          Comprising Its Target Site In Human Ref-1 (Residues 59
          - 71 Of The P50 Subunit Of Nfkb), Nmr, Minimized
          Average Structure
 pdb|1MDI|A Chain A, High Resolution Solution Nmr Structure Of Mixed
          Disulfide Intermediate Between Mutant Human Thioredoxin
          And A 13 Residue Peptide Comprising Its Target Site In
          Human Nfkb
 pdb|1MDJ|A Chain A, High Resolution Solution Nmr Structure Of Mixed
          Disulfide Intermediate Between Human Thioredoxin (C35a,
          C62a, C69a, C73a) Mutant And A 13 Residue Peptide
          Comprising Its Target Site In Human Nfkb (Residues
          56-68 Of The P50 Subunit Of Nfkb)
 pdb|1MDK|A Chain A, High Resolution Solution Nmr Structure Of Mixed
          Disulfide Intermediate Between Human Thioredoxin (C35a,
          C62a, C69a, C73a) Mutant And A 13 Residue Peptide
          Comprising Its Target Site In Human Nfkb (Residues
          56-68 Of The P50 Subunit Of Nfkb)
          Length = 105

 Score = 50.4 bits (119), Expect = 3e-08
 Identities = 22/67 (32%), Positives = 39/67 (57%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+WC   + I+P   +L++ Y   + F +V  D++QD+     ++  PT  F+K
Sbjct: 23 VVVDFSATWCGPAKMIKPFFHSLSEKYSNVI-FLEVDVDDAQDVASEAEVKATPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1ERW|   Human Thioredoxin Double Mutant With Cys 32 Replaced By Ser And
          Cys 35 Replaced By Ser
          Length = 105

 Score = 45.4 bits (106), Expect = 9e-07
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 1/67 (1%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYK 78
          VVV+  A+W    + I+P   +L++ Y   + F +V  D+ QD+     ++ +PT  F+K
Sbjct: 23 VVVDFSATWSGPSKMIKPFFHSLSEKYSNVI-FLEVDVDDCQDVASECEVKCMPTFQFFK 81

Query: 79 NAKEVGE 85
            ++VGE
Sbjct: 82 KGQKVGE 88
>pdb|1MEK|   Human Protein Disulfide Isomerase, Nmr, 40 Structures
          Length = 120

 Score = 45.4 bits (106), Expect = 9e-07
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 4  MINGKNYAEKIA-HQAVVVNVGASWCPDCRKIEPIMENLAKTYKGK---VEFFKVSFDES 59
          ++   N+AE +A H+ ++V   A WC  C+ + P     A   K +   +   KV   E 
Sbjct: 11 VLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEE 70

Query: 60 QDLKESLGIRKIPTLIFYKN 79
           DL +  G+R  PT+ F++N
Sbjct: 71 SDLAQQYGVRGYPTIKFFRN 90
>pdb|1F9M|A Chain A, Crystal Structure Of Thioredoxin F From Spinach
          Chloroplast (Short Form)
 pdb|1F9M|B Chain B, Crystal Structure Of Thioredoxin F From Spinach
          Chloroplast (Short Form)
          Length = 112

 Score = 42.0 bits (97), Expect = 1e-05
 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 2/68 (2%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFD-ESQDLKESLGIRKIPTLIFY 77
          VV+++   WC  C+ + P  E LA+ Y   + F K+  + E++ L + LGIR +PT    
Sbjct: 28 VVLDMFTQWCGPCKAMAPKYEKLAEEYLDVI-FLKLDCNQENKTLAKELGIRVVPTFKIL 86

Query: 78 KNAKEVGE 85
          K    VGE
Sbjct: 87 KENSVVGE 94
>pdb|1FAA|A Chain A, Crystal Structure Of Thioredoxin F From Spinach
           Chloroplast (Long Form)
          Length = 124

 Score = 42.0 bits (97), Expect = 1e-05
 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 2/68 (2%)

Query: 19  VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFD-ESQDLKESLGIRKIPTLIFY 77
           VV+++   WC  C+ + P  E LA+ Y   + F K+  + E++ L + LGIR +PT    
Sbjct: 40  VVLDMFTQWCGPCKAMAPKYEKLAEEYLDVI-FLKLDCNQENKTLAKELGIRVVPTFKIL 98

Query: 78  KNAKEVGE 85
           K    VGE
Sbjct: 99  KENSVVGE 106
>pdb|1THX|   Thioredoxin-2
          Length = 115

 Score = 41.2 bits (95), Expect = 2e-05
 Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 5/90 (5%)

Query: 15  AHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTL 74
           A Q V+V   ASWC  C+ + P++   A TY  +++  K+  D +    +   +  +P L
Sbjct: 24  AEQPVLVYFWASWCGPCQLMSPLINLAANTYSDRLKVVKLEIDPNPTTVKKYKVEGVPAL 83

Query: 75  IFYKNAKEVGERLVEPSSQKPIEDALKALL 104
              K     GE++++ +     +D L + L
Sbjct: 84  RLVK-----GEQILDSTEGVISKDKLLSFL 108
>pdb|1FG4|A Chain A, Structure Of Tryparedoxin Ii
 pdb|1FG4|B Chain B, Structure Of Tryparedoxin Ii
          Length = 149

 Score = 33.9 bits (76), Expect = 0.003
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 3/54 (5%)

Query: 14 IAHQAVVVNVGASWCPDCRKIEPIMENLAKTY--KGKVEFFKVSFDES-QDLKE 64
          +A + V     ASWCP CR   P + +  K +  K   E   +S+DES +D K+
Sbjct: 26 LAGKTVFFYFSASWCPPCRAFTPQLIDFYKAHAEKKNFEVMLISWDESAEDFKD 79
>pdb|1QGV|A Chain A, Human Spliceosomal Protein U5-15kd
          Length = 142

 Score = 33.1 bits (74), Expect = 0.005
 Identities = 15/67 (22%), Positives = 31/67 (45%)

Query: 17 QAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIF 76
          + VV+  G  W P C K++ ++ ++A+  K     + V   E  D  +   +    T++F
Sbjct: 24 RVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMF 83

Query: 77 YKNAKEV 83
          +   K +
Sbjct: 84 FFRNKHI 90
>pdb|1EZK|A Chain A, Crystal Structure Of Recombinant Tryparedoxin I
          Length = 153

 Score = 30.4 bits (67), Expect = 0.031
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 6  NGKNYAEKIAHQAVVVNVGASWCPDCRKIEP-IMENLAKTYKGK-VEFFKVSFDESQD 61
          +G+   + +A + V     ASWCP CR   P ++E   K ++ K  E    ++DE +D
Sbjct: 17 DGEVEVKSLAGKLVFFYFSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEED 74
>pdb|1EWX|A Chain A, Crystal Structure Of Native Tryparedoxin I From
          Crithidia Fasciculata
          Length = 146

 Score = 30.4 bits (67), Expect = 0.031
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 6  NGKNYAEKIAHQAVVVNVGASWCPDCRKIEP-IMENLAKTYKGK-VEFFKVSFDESQD 61
          +G+   + +A + V     ASWCP CR   P ++E   K ++ K  E    ++DE +D
Sbjct: 18 DGEVEVKSLAGKLVFFYFSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEED 75
>pdb|1QK8|A Chain A, Tryparedoxin-I From Crithidia Fasciculata
          Length = 146

 Score = 30.4 bits (67), Expect = 0.031
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 6  NGKNYAEKIAHQAVVVNVGASWCPDCRKIEP-IMENLAKTYKGK-VEFFKVSFDESQD 61
          +G+   + +A + V     ASWCP CR   P ++E   K ++ K  E    ++DE +D
Sbjct: 18 DGEVEVKSLAGKLVFFYFSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEED 75
>pdb|1I5G|A Chain A, Tryparedoxin Ii Complexed With Glutathionylspermidine
          Length = 144

 Score = 30.0 bits (66), Expect = 0.040
 Identities = 18/54 (33%), Positives = 27/54 (49%), Gaps = 3/54 (5%)

Query: 14 IAHQAVVVNVGASWCPDCRKIEPIMENLAKTY--KGKVEFFKVSFDES-QDLKE 64
          +A + V     ASWCP  R   P + +  K +  K   E   +S+DES +D K+
Sbjct: 26 LAGKTVFFYFSASWCPPSRAFTPQLIDFYKAHAEKKNFEVMLISWDESAEDFKD 79
>pdb|1JFU|B Chain B, Crystal Structure Of The Soluble Domain Of Tlpa From
           Bradyrhizobium Japonicum
 pdb|1JFU|A Chain A, Crystal Structure Of The Soluble Domain Of Tlpa From
           Bradyrhizobium Japonicum
          Length = 186

 Score = 29.6 bits (65), Expect = 0.053
 Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 17  QAVVVNVGASWCPDCRKIEPIMENLAKTYKG-KVEFFKVSFDESQD------LKES---- 65
           + ++VN+ A+WC  CRK  P ++ L     G   E   ++ D          LKE+    
Sbjct: 61  KTLLVNLWATWCVPCRKEMPALDELQGKLSGPNFEVVAINIDTRDPEKPKTFLKEANLTR 120

Query: 66  LGIRKIPTLIFYKNAKEVGERLVEPSS 92
           LG         +++ K +G  L  P+S
Sbjct: 121 LGYFNDQKAKVFQDLKAIGRALGMPTS 147
>pdb|1KNG|A Chain A, Crystal Structure Of Ccmg Reducing Oxidoreductase At
          1.14 A
          Length = 156

 Score = 28.1 bits (61), Expect = 0.15
 Identities = 11/24 (45%), Positives = 14/24 (57%)

Query: 20 VVNVGASWCPDCRKIEPIMENLAK 43
          +VNV ASWC  C    P++  L K
Sbjct: 46 LVNVWASWCVPCHDEAPLLTELGK 69
>pdb|1EI3|A Chain A, Crystal Structure Of Native Chicken Fibrinogen
 pdb|1EI3|D Chain D, Crystal Structure Of Native Chicken Fibrinogen
          Length = 491

 Score = 25.4 bits (54), Expect = 0.99
 Identities = 12/62 (19%), Positives = 31/62 (49%)

Query: 28  CPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAKEVGERL 87
           CP C +++ I+++  + Y  +++  +    +SQ+  ++     + T+   K   E  ++L
Sbjct: 46  CPSCCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQL 105

Query: 88  VE 89
            E
Sbjct: 106 DE 107
>pdb|1JDI|A Chain A, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
 pdb|1JDI|B Chain B, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
 pdb|1JDI|C Chain C, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
 pdb|1JDI|D Chain D, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
 pdb|1JDI|E Chain E, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
 pdb|1JDI|F Chain F, Crystal Structure Of L-Ribulose-5-Phosphate 4-Epimerase
          Length = 231

 Score = 23.9 bits (50), Expect = 2.9
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 7   GKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGK 48
           GKN AE   H A+V+   A     CR++ P + ++ +T   K
Sbjct: 177 GKN-AEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLNK 217
>pdb|2ALR|   Aldehyde Reductase
          Length = 324

 Score = 23.5 bits (49), Expect = 3.8
 Identities = 14/37 (37%), Positives = 17/37 (45%), Gaps = 3/37 (8%)

Query: 65 SLGIRKIPTLIFYKNAKEVGERLVE---PSSQKPIED 98
          S+G R I     Y N  E+GE L E   P    P E+
Sbjct: 37 SVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREE 73
>pdb|1BED|   Structure Of Disulfide Oxidoreductase
          Length = 181

 Score = 23.5 bits (49), Expect = 3.8
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 2/40 (5%)

Query: 19 VVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFK--VSF 56
          VV    + +CP C   EPI+  L +      +F K  VSF
Sbjct: 21 VVSEFFSFYCPHCNTFEPIIAQLKQQLPEGAKFQKNHVSF 60
>pdb|1BG1|A Chain A, Three-Dimensional Structure Of The Stat3b Homodimer
          Bound To Dna
          Length = 722

 Score = 23.1 bits (48), Expect = 4.9
 Identities = 13/57 (22%), Positives = 27/57 (46%)

Query: 30 DCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAKEVGER 86
          D R +E + +  + T+  ++  F   + ESQD   +       TL+F+    E+ ++
Sbjct: 11 DTRYLEQLHQLYSDTFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQ 67
>pdb|1QFX|B Chain B, Ph 2.5 Acid Phosphatase From Aspergillus Niger
 pdb|1QFX|A Chain A, Ph 2.5 Acid Phosphatase From Aspergillus Niger
          Length = 460

 Score = 23.1 bits (48), Expect = 4.9
 Identities = 11/20 (55%), Positives = 13/20 (65%)

Query: 81  KEVGERLVEPSSQKPIEDAL 100
           K  GER   PS+ K IE+AL
Sbjct: 61  KRHGERYPSPSAGKDIEEAL 80
>pdb|1HUS|   Ribosomal Protein S7
          Length = 155

 Score = 23.1 bits (48), Expect = 4.9
 Identities = 15/56 (26%), Positives = 27/56 (47%), Gaps = 2/56 (3%)

Query: 32  RKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAKEVGERL 87
           + + P++E  A+   G    ++V  +   D + SLG+R +      +N K   ERL
Sbjct: 66  KNVXPVLEVRARRVGGAN--YQVPVEVRPDRRVSLGLRWLVQYARLRNEKTXEERL 119
>pdb|1MTZ|A Chain A, Crystal Structure Of The Tricorn Interacting Factor F1
 pdb|1MU0|A Chain A, Crystal Structure Of The Tricorn Interacting Factor F1
           Complex With Pck
          Length = 293

 Score = 22.7 bits (47), Expect = 6.4
 Identities = 17/59 (28%), Positives = 24/59 (39%), Gaps = 2/59 (3%)

Query: 27  WCPDCRKIEPIME--NLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAKEV 83
           W P+  K     E  N+ +   G  EF      +  D+ + +   KIPTLI      EV
Sbjct: 188 WPPEVLKSLEYAERRNVYRIMNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEYDEV 246
>pdb|1GZS|B Chain B, Crystal Structure Of The Complex Between The Gef Domain Of
           The Salmonella Typhimurium Sope Toxin And Human Cdc42
 pdb|1GZS|D Chain D, Crystal Structure Of The Complex Between The Gef Domain Of
           The Salmonella Typhimurium Sope Toxin And Human Cdc42
          Length = 165

 Score = 22.7 bits (47), Expect = 6.4
 Identities = 13/38 (34%), Positives = 18/38 (47%)

Query: 8   KNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTY 45
           K YAEKI    V         P  ++ + I+EN+A  Y
Sbjct: 123 KIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKY 160
>pdb|1CWN|   Crystal Structure Of Porcine Aldehyde Reductase Holoenzyme
          Length = 324

 Score = 22.7 bits (47), Expect = 6.4
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 3/37 (8%)

Query: 65 SLGIRKIPTLIFYKNAKEVGERLVE---PSSQKPIED 98
          ++G R I     Y N  E+GE L E   P    P E+
Sbjct: 37 TVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREE 73
>pdb|1MT3|A Chain A, Crystal Structure Of The Tricorn Interacting Factor
           Selenomethionine-F1
          Length = 293

 Score = 22.7 bits (47), Expect = 6.4
 Identities = 17/59 (28%), Positives = 24/59 (39%), Gaps = 2/59 (3%)

Query: 27  WCPDCRKIEPIME--NLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAKEV 83
           W P+  K     E  N+ +   G  EF      +  D+ + +   KIPTLI      EV
Sbjct: 188 WPPEVLKSLEYAERRNVYRIXNGPNEFTITGTIKDWDITDKISAIKIPTLITVGEYDEV 246
>pdb|1AE4|   Aldehyde Reductase Complexed With Cofactor And Inhibitor, Alpha
          Carbon Atoms Only
          Length = 325

 Score = 22.7 bits (47), Expect = 6.4
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 3/37 (8%)

Query: 65 SLGIRKIPTLIFYKNAKEVGERLVE---PSSQKPIED 98
          ++G R I     Y N  E+GE L E   P    P E+
Sbjct: 38 TVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREE 74
>pdb|1C9W|A Chain A, Cho Reductase With Nadp+
          Length = 315

 Score = 22.3 bits (46), Expect = 8.4
 Identities = 11/30 (36%), Positives = 14/30 (46%)

Query: 67 GIRKIPTLIFYKNAKEVGERLVEPSSQKPI 96
          G R I     Y N  EVGE + E   +K +
Sbjct: 38 GYRHIDCAYAYYNEHEVGEAIQEKIKEKAV 67
  Database: /var/www/html/HP/blast_new/blast/db/pdbaa
    Posted date:  Dec 20, 2002 11:08 AM
  Number of letters in database: 2,899,336
  Number of sequences in database:  13,198
  
Lambda     K      H
   0.315    0.133    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 585,881
Number of Sequences: 13198
Number of extensions: 21450
Number of successful extensions: 87
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 36
Number of HSP's gapped (non-prelim): 46
length of query: 104
length of database: 2,899,336
effective HSP length: 80
effective length of query: 24
effective length of database: 1,843,496
effective search space: 44243904
effective search space used: 44243904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 46 (22.3 bits)