BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15646180|ref|NP_208364.1| conserved hypothetical
protein [Helicobacter pylori 26695]
(254 letters)
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
13,198 sequences; 2,899,336 total letters
Searching...........................done
Score E
Sequences producing significant alignments: (bits) Value
pdb|1J6O|A Chain A, Crystal Structure Of Conserved Hypothet... 153 2e-38
pdb|1E1A|A Chain A, Crystal Structure Of Dfpase From Loligo... 27 3.0
pdb|1GP6|A Chain A, Anthocyanidin Synthase From Arabidopsis... 26 3.9
pdb|1GYJ|A Chain A, The Crystal Structure Of Ydce, A 4-Oxal... 26 3.9
pdb|1CEN| Cellulase (Celc) Mutant With Glu 140 Replaced B... 26 5.1
pdb|1CEC| Glycosyl Hydrolase, Cellulase, Family A5 OF Cel... 26 5.1
pdb|1A4X|A Chain A, Pyrr, The Bacillus Subtilis Pyrimidine ... 26 5.1
pdb|1M6H|A Chain A, Human Glutathione-Dependent Formaldehyd... 25 6.7
pdb|1QOQ|B Chain B, Crystal Structure Of Wild-Type Tryptoph... 25 6.7
pdb|1GP4|A Chain A, Anthocyanidin Synthase From Arabidopsis... 25 6.7
pdb|1K3U|B Chain B, Crystal Structure Of Wild-Type Tryptoph... 25 8.7
pdb|1UBS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) With... 25 8.7
pdb|1BKS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) From... 25 8.7
pdb|1A50|B Chain B, Crystal Structure Of Wild-Type Tryptoph... 25 8.7
pdb|1BEU|B Chain B, Trp Synthase (D60n-Ipp-Ser) With K+ >gi... 25 8.7
pdb|2TYS|B Chain B, Crystal Structures Of Mutant (Betak87t)... 25 8.7
>pdb|1J6O|A Chain A, Crystal Structure Of Conserved Hypothetical Protein
(Tm0667) From Thermotoga Maritima At 1.8 A Resolution
Length = 268
Score = 153 bits (386), Expect = 2e-38
Identities = 81/258 (31%), Positives = 147/258 (56%), Gaps = 17/258 (6%)
Query: 3 IDTHCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIGA 62
+DTH HL +++D V+ E + V G +++D +++++S+ + +F ++G
Sbjct: 14 VDTHAHLHFHQFDDDRNAVISSFEENNIEFVVNVGVNLEDSKKSLDLSKTSDRIFCSVGV 73
Query: 63 HPYDVESFDESLFE---KFVGHQKCVAIGECGLDYYRLPELNERENYKSKQKEIFTKQIE 119
HP+D + E E KF +K VAIGE GLD++R ++ E QK +F +QIE
Sbjct: 74 HPHDAKEVPEDFIEHLEKFAKDEKVVAIGETGLDFFR--NISPAE----VQKRVFVEQIE 127
Query: 120 FSIQHNKPLIIHIREASFDSLNLLK--NYPKAFGVLHCFNAD----GMLLELSDRFYYGI 173
+ + N PL++HIR+A ++ +L+ + P+ GV+H F++D ++L F GI
Sbjct: 128 LAGKLNLPLVVHIRDAYSEAYEILRTESLPEKRGVIHAFSSDYEWAKKFIDLG--FLLGI 185
Query: 174 GGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPTYIPLIAQKIAEIIN 233
GG T+ + L E++ ++ ++LETD P+L P PFRG RN P Y+ + + I++++
Sbjct: 186 GGPVTYPKNEALREVVKRVGLEYIVLETDCPFLPPQPFRGKRNEPKYLKYVVETISQVLG 245
Query: 234 IETEELASLSTHNAQMLF 251
+ ++ +T NA+ +F
Sbjct: 246 VPEAKVDEATTENARRIF 263
>pdb|1E1A|A Chain A, Crystal Structure Of Dfpase From Loligo Vulgaris
Length = 314
Score = 26.6 bits (57), Expect = 3.0
Identities = 15/70 (21%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 144 KNYPKAFGVLHCFNADGMLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDS 203
++ + FG ++CF DG ++++ F + G N R P ++ ET +
Sbjct: 146 RSMQEKFGSIYCFTTDGQMIQVDTAFQFPNGIAVRHMNDGR--------PYQLIVAETPT 197
Query: 204 PYLTPHPFRG 213
L + +G
Sbjct: 198 KKLWSYDIKG 207
>pdb|1GP6|A Chain A, Anthocyanidin Synthase From Arabidopsis Thaliana Complexed
With Trans-Dihydroquercetin (With 30 Min Exposure To O2)
pdb|1GP5|A Chain A, Anthocyanidin Synthase From Arabidopsis Thaliana Complexed
With Trans-Dihydroquercetin
Length = 356
Score = 26.2 bits (56), Expect = 3.9
Identities = 15/44 (34%), Positives = 22/44 (49%)
Query: 10 DHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKF 53
D K EN +EE+ K SL+ GV + G + R + E+F
Sbjct: 59 DEKIRENCIEELKKASLDWGVMHLINHGIPADLMERVKKAGEEF 102
>pdb|1GYJ|A Chain A, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
pdb|1GYJ|B Chain B, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
pdb|1GYX|A Chain A, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
pdb|1GYX|B Chain B, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
pdb|1GYY|A Chain A, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
pdb|1GYY|B Chain B, The Crystal Structure Of Ydce, A 4-Oxalocrotonate
Tautomerase Homologue From Escherichia Coli, Confirms
The Structural Basis For Oligomer Diversity
Length = 76
Score = 26.2 bits (56), Expect = 3.9
Identities = 12/44 (27%), Positives = 24/44 (54%)
Query: 8 HLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISE 51
H+D K + +L+E K +L +T +I + KD + +I + +
Sbjct: 2 HIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQ 45
>pdb|1CEN| Cellulase (Celc) Mutant With Glu 140 Replaced By Gln Complexed
With Cellohexaose
pdb|1CEO| Cellulase (Celc) Mutant With Glu 140 Replaced By Gln
Length = 343
Score = 25.8 bits (55), Expect = 5.1
Identities = 17/73 (23%), Positives = 33/73 (44%), Gaps = 7/73 (9%)
Query: 70 FDESLFEKFVGHQKCVAIGECGLDYYRLP---ELNEREN----YKSKQKEIFTKQIEFSI 122
F + F+ F+ + I E G D+ RLP + E ++ YK + +E+
Sbjct: 20 FSKEHFDTFITEKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCK 79
Query: 123 QHNKPLIIHIREA 135
++N L++ + A
Sbjct: 80 KYNLGLVLDMHHA 92
>pdb|1CEC| Glycosyl Hydrolase, Cellulase, Family A5 OF CellulasesGLYCOSYL
HYDROLASES, CLOSTRIDIUM THERMOCELLUM, Endoglucanase C
Mol_id: 1; Molecule: Endoglucanase Celc; Chain: Null;
Synonym: Egc, Cellulase Celc, Endo-1,4-Beta-Glucanase
Celc; Ec: 3.2.1.4; Engineered: Yes; Other_details:
Cellulase Family A5
Length = 343
Score = 25.8 bits (55), Expect = 5.1
Identities = 17/73 (23%), Positives = 33/73 (44%), Gaps = 7/73 (9%)
Query: 70 FDESLFEKFVGHQKCVAIGECGLDYYRLP---ELNEREN----YKSKQKEIFTKQIEFSI 122
F + F+ F+ + I E G D+ RLP + E ++ YK + +E+
Sbjct: 20 FSKEHFDTFITEKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCK 79
Query: 123 QHNKPLIIHIREA 135
++N L++ + A
Sbjct: 80 KYNLGLVLDMHHA 92
>pdb|1A4X|A Chain A, Pyrr, The Bacillus Subtilis Pyrimidine Biosynthetic
Operon Repressor, Hexameric Form
pdb|1A4X|B Chain B, Pyrr, The Bacillus Subtilis Pyrimidine Biosynthetic
Operon Repressor, Hexameric Form
pdb|1A3C| Pyrr, The Bacillus Subtilis Pyrimidine Biosynthetic Operon
Repressor, Dimeric Form
Length = 181
Score = 25.8 bits (55), Expect = 5.1
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 9 LDHKDYENDLEEVLKESLE--KGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIGAHPYD 66
LD + L + E +E KG+ C++ G + + A ++E+ E I +P
Sbjct: 8 LDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGIYLAKRLAERIE----QIEGNPVT 63
Query: 67 VESFDESLF 75
V D +L+
Sbjct: 64 VGEIDITLY 72
>pdb|1M6H|A Chain A, Human Glutathione-Dependent Formaldehyde Dehydrogenase
pdb|1M6H|B Chain B, Human Glutathione-Dependent Formaldehyde Dehydrogenase
pdb|1M6W|A Chain A, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase And 12-Hydroxydodecanoic Acid
pdb|1M6W|B Chain B, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase And 12-Hydroxydodecanoic Acid
pdb|1MA0|A Chain A, Ternary Complex Of Human Glutathione-Dependent
Formaldehyde Dehydrogenase With Nad+ And Dodecanoic Acid
pdb|1MA0|B Chain B, Ternary Complex Of Human Glutathione-Dependent
Formaldehyde Dehydrogenase With Nad+ And Dodecanoic Acid
pdb|1MP0|A Chain A, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase With Nad(H)
pdb|1MP0|B Chain B, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase With Nad(H)
pdb|1TEH|A Chain A, Structure Of Human Liver Chichi Alcohol Dehydrogenase (A
Glutathione-Dependent Formaldehyde Dehydrogenase)
pdb|1TEH|B Chain B, Structure Of Human Liver Chichi Alcohol Dehydrogenase (A
Glutathione-Dependent Formaldehyde Dehydrogenase)
Length = 373
Score = 25.4 bits (54), Expect = 6.7
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 5 THCHLDHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKFEGVFFAIG 61
T C ++ +D+ ++EVL E + GV ++K + A+E K GV +G
Sbjct: 237 TEC-INPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVG 292
>pdb|1QOQ|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With Indole Glycerol Phosphate
Length = 396
Score = 25.4 bits (54), Expect = 6.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 124 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALADWSGSYETA 183
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 184 HYMLGTAAGPHPYPTIVREFQRMIGEETK 212
>pdb|1GP4|A Chain A, Anthocyanidin Synthase From Arabidopsis Thaliana
(Selenomethionine Substituted)
Length = 356
Score = 25.4 bits (54), Expect = 6.7
Identities = 15/44 (34%), Positives = 21/44 (47%)
Query: 10 DHKDYENDLEEVLKESLEKGVTQCVIPGADMKDLNRAIEISEKF 53
D K EN +EE+ K SL+ GV + G R + E+F
Sbjct: 59 DEKIRENCIEELKKASLDWGVXHLINHGIPADLXERVKKAGEEF 102
>pdb|1K3U|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With N-[1h-Indol-3-Yl-Acetyl]aspartic Acid
pdb|1K7E|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With N-[1h-Indol-3-Yl-Acetyl]glycine Acid
pdb|1K7F|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With N-[1h-Indol-3-Yl-Acetyl]valine Acid
pdb|1QOP|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With Indole Propanol Phosphate
Length = 396
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 124 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 183
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 184 HYMLGTAAGPHPYPTIVREFQRMIGEETK 212
>pdb|1UBS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) With A Mutation Of Lys
87 ->thr In The B Subunit And In The Presence Of Ligand
L-Serine
pdb|2TRS|B Chain B, Crystal Structures Of Mutant (Betak87t) Tryptophan
Synthase Alpha2 Beta2 Complex With Ligands Bound To The
Active Sites Of The Alpha And Beta Subunits Reveal
Ligand-Induced Conformational Changes
pdb|2TSY|B Chain B, Crystal Structures Of Mutant (Betak87t) Tryptophan
Synthase Alpha2 Beta2 Complex With Ligands Bound To The
Active Sites Of The Alpha And Beta Subunits Reveal
Ligand-Induced Conformational Changes
Length = 397
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETK 213
>pdb|1BKS|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) From Salmonella
Typhimurium
pdb|1TTQ|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) In The Presence Of
Potassium At Room Temperature
pdb|1TTP|B Chain B, Tryptophan Synthase (E.C.4.2.1.20) In The Presence Of
Cesium, Room Temperature
pdb|1CW2|B Chain B, Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Hydroxyphenylsulfinyl)-Butylphosphonic Acid
pdb|1C8V|B Chain B, Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Hydroxyphenylthio)-Butylphosphonic Acid
pdb|1A5S|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With 5-Fluoroindole Propanol Phosphate And
L-Ser Bound As Amino Acrylate To The Beta Site
pdb|1C29|B Chain B, Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Hydroxyphenylthio)-1-Butenylphosphonic Acid
pdb|1C9D|B Chain B, Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Hydroxy-4-Fluorophenylthio)-Butylphosphonic Acid
pdb|1CX9|B Chain B, Crystal Structure Of The Complex Of Bacterial Tryptophan
Synthase With The Transition State Analogue Inhibitor
4-(2- Aminophenylthio)-Butylphosphonic Acid
Length = 397
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETK 213
>pdb|1A50|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Complexed With 5-Fluoroindole Propanol Phosphate
pdb|2WSY|B Chain B, Crystal Structure Of Wild-Type Tryptophan Synthase
Length = 396
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 124 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 183
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 184 HYMLGTAAGPHPYPTIVREFQRMIGEETK 212
>pdb|1BEU|B Chain B, Trp Synthase (D60n-Ipp-Ser) With K+
pdb|1A5A|B Chain B, Cryo-Crystallography Of A True Substrate,
Indole-3-Glycerol Phosphate, Bound To A Mutant
(Alphad60n) Tryptophan Synthase Alpha2beta2 Complex
Reveals The Correct Orientation Of Active Site Alpha Glu
49
pdb|1A5B|B Chain B, Cryo-Crystallography Of A True Substrate,
Indole-3-Glycerol Phosphate, Bound To A Mutant (Alpha
D60n) Tryptophan Synthase Alpha2beta2 Complex Reveals
The Correct Orientation Of Active Site Alpha Glu 49
Length = 397
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETK 213
>pdb|2TYS|B Chain B, Crystal Structures Of Mutant (Betak87t) Tryptophan
Synthase Alpha2 Beta2 Complex With Ligands Bound To The
Active Sites Of The Alpha And Beta Subunits Reveal
Ligand-Induced Conformational Changes
Length = 397
Score = 25.0 bits (53), Expect = 8.7
Identities = 24/89 (26%), Positives = 33/89 (36%), Gaps = 13/89 (14%)
Query: 162 LLELSDRFYYGIGGV-----STFKNAKRLVEILP--------KIPKNRLLLETDSPYLTP 208
LL L R Y G V + F+ E++P K N L + Y T
Sbjct: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
Query: 209 HPFRGTRNSPTYIPLIAQKIAEIINIETE 237
H GT P P I ++ +I ET+
Sbjct: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETK 213
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
Posted date: Dec 20, 2002 11:08 AM
Number of letters in database: 2,899,336
Number of sequences in database: 13,198
Lambda K H
0.320 0.140 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,465,699
Number of Sequences: 13198
Number of extensions: 61228
Number of successful extensions: 146
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 136
Number of HSP's gapped (non-prelim): 16
length of query: 254
length of database: 2,899,336
effective HSP length: 86
effective length of query: 168
effective length of database: 1,764,308
effective search space: 296403744
effective search space used: 296403744
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 53 (25.0 bits)