BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15644967|ref|NP_207137.1| hypothetical protein
[Helicobacter pylori 26695]
(116 letters)
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
13,198 sequences; 2,899,336 total letters
Searching...........................done
Score E
Sequences producing significant alignments: (bits) Value
pdb|1L72| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Re... 43 8e-06
pdb|1L28| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 43 8e-06
pdb|192L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec:... 43 8e-06
pdb|201L|B Chain B, Lysozyme (E.C.3.2.1.17) Insertion Mutan... 43 8e-06
pdb|1TLA| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 43 8e-06
pdb|1L73| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Re... 43 8e-06
pdb|1DYG| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2... 43 1e-05
pdb|176L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Leu... 42 1e-05
pdb|1L59| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 42 1e-05
pdb|1L10| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 42 2e-05
pdb|1G0P|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 42 2e-05
pdb|1L01| Lysozyme (E.C.3.2.1.17) (Double Mutant With Thr... 42 2e-05
pdb|1LLH|A Chain A, Are Carboxy Terminii Of Helices Coded B... 42 2e-05
pdb|160L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 42 2e-05
pdb|1L51| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Rep... 42 2e-05
pdb|127L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 42 2e-05
pdb|1L15| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 42 2e-05
pdb|1L49| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Rep... 42 2e-05
pdb|1QUG|A Chain A, E108v Mutant Of T4 Lysozyme 42 2e-05
pdb|1L48| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Rep... 42 2e-05
pdb|1DYA| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2... 42 2e-05
pdb|1L50| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Rep... 42 2e-05
pdb|1QS9|A Chain A, The Introduction Of Strain And Its Effe... 42 2e-05
pdb|137L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ser... 41 3e-05
pdb|107L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 41 3e-05
pdb|1L71| Lysozyme (E.C.3.2.1.17) (Mutant With Glu 128 Re... 41 3e-05
pdb|247L| The Response Of T4 Lysozyme To Large-To-Small S... 41 3e-05
pdb|1L75| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Re... 41 3e-05
pdb|1L61| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 38 Rep... 41 3e-05
pdb|238L| The Response Of T4 Lysozyme To Large-To-Small S... 41 3e-05
pdb|1L11| Sgamma97-Beta-Mercaptoethanol-Lysozyme (E.C.3.2... 41 3e-05
pdb|1L25| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 41 4e-05
pdb|216L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ser... 41 4e-05
pdb|1L38| Lysozyme (E.C.3.2.1.17) (Mutant With Gln 123 Re... 41 4e-05
pdb|1L21| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 55 Rep... 41 4e-05
pdb|191L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec:... 41 4e-05
pdb|1DYE| Lysozyme (E.C.3.2.1.17) Mutant With Val 131 Rep... 41 4e-05
pdb|1L77| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 41 4e-05
pdb|1L32| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 41 4e-05
pdb|1L37| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 115 Re... 41 4e-05
pdb|1L36| Lysozyme (E.C.3.2.1.17) Mutant With Glu 128 Rep... 41 4e-05
pdb|177L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 41 4e-05
pdb|1L67| Lysozyme (E.C.3.2.1.17) (Mutant With Leu 46 Rep... 41 4e-05
pdb|1L92| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 41 4e-05
pdb|234L| T4 Lysozyme Mutant M106l 41 4e-05
pdb|1CU3|A Chain A, T4 Lysozyme Mutant V87m 41 4e-05
pdb|1L27| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 40 5e-05
pdb|1L39| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 5e-05
pdb|128L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 5e-05
pdb|1L33| Lysozyme (E.C.3.2.1.17) (Mutant With Val 131 Re... 40 5e-05
pdb|1L80| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 5e-05
pdb|119L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 5e-05
pdb|246L| The Response Of T4 Lysozyme To Large-To-Small S... 40 5e-05
pdb|1CV1|A Chain A, T4 Lysozyme Mutant V111m 40 5e-05
pdb|1CUQ|A Chain A, T4 Lysozyme Mutant V103m 40 5e-05
pdb|1L82| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 5e-05
pdb|1QTB|A Chain A, The Introduction Of Strain And Its Effe... 40 5e-05
pdb|1LYE| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 5e-05
pdb|210L| Protein Structure Plasticity Exemplified By Ins... 40 5e-05
pdb|1L94| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 5e-05
pdb|2L78| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 5e-05
pdb|103L| Phage T4 Lysozyme Insertion Mutant With Ser, Le... 40 5e-05
pdb|1L46| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 147 Re... 40 5e-05
pdb|122L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 5e-05
pdb|1QS5|A Chain A, The Introduction Of Strain And Its Effe... 40 5e-05
pdb|1L62| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 5e-05
pdb|189L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Repla... 40 5e-05
pdb|1QTH|A Chain A, The Introduction Of Strain And Its Effe... 40 5e-05
pdb|1QUO|A Chain A, L99aE108V MUTANT OF T4 LYSOZYME 40 5e-05
pdb|1G0Q|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 5e-05
pdb|1L60| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 113 Re... 40 5e-05
pdb|1C61|A Chain A, T4 Lysozyme Mutant C54tC97AF153A IN THE... 40 5e-05
pdb|221L| Lysozyme (E.C.3.2.1.17) Mutant With Ala 49 Repl... 40 5e-05
pdb|1L07| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 5e-05
pdb|1CU2|A Chain A, T4 Lysozyme Mutant L84m 40 5e-05
pdb|1L68| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 44 Rep... 40 7e-05
pdb|1L86| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|217L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|108L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|1DYF| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2... 40 7e-05
pdb|109L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|110L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|111L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|112L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|1L17| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Repl... 40 7e-05
pdb|113L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|219L| Protein Structure Plasticity Exemplified By Ins... 40 7e-05
pdb|114L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|115L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Repl... 40 7e-05
pdb|1L16| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 156 Re... 40 7e-05
pdb|1G0M|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|258L|A Chain A, An Adaptable Metal-Binding Site Enginee... 40 7e-05
pdb|256L| Bacteriophage T4 Lysozyme >gi|515066|pdb|150L|A... 40 7e-05
pdb|237L| The Response Of T4 Lysozyme To Large-To-Small S... 40 7e-05
pdb|1L04| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|1CU0|A Chain A, T4 Lysozyme Mutant I78m 40 7e-05
pdb|233L| T4 Lysozyme Mutant M120l 40 7e-05
pdb|1L20| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 144 Re... 40 7e-05
pdb|126L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L14| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|1CV6|A Chain A, T4 Lysozyme Mutant V149m 40 7e-05
pdb|1G0L|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1L87| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L08| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|242L| The Response Of T4 Lysozyme To Large-To-Small S... 40 7e-05
pdb|232L| T4 Lysozyme Mutant M120k 40 7e-05
pdb|1L53| Lysozyme (E.C.3.2.1.17) (Mutant With Val 149 Re... 40 7e-05
pdb|1G0G|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1L65| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 47 Rep... 40 7e-05
pdb|1L98| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Rep... 40 7e-05
pdb|190L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec:... 40 7e-05
pdb|170L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L66| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 43 Rep... 40 7e-05
pdb|1G06|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1L52| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 152 Re... 40 7e-05
pdb|155L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L99| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Rep... 40 7e-05
pdb|1LYJ| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 7e-05
pdb|1L95| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|245L| The Response Of T4 Lysozyme To Large-To-Small S... 40 7e-05
pdb|1JQU|A Chain A, Are Carboxy Terminii Of Helices Coded B... 40 7e-05
pdb|1L06| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|166L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|120L| Lysozyme (E.C.3.2.1.17) Mutant With Ala 41 Repl... 40 7e-05
pdb|230L| T4 Lysozyme Mutant M6l 40 7e-05
pdb|151L| Lysozyme (E.C.3.2.1.17) Mutant With Thr 34, Lys... 40 7e-05
pdb|1D2Y|A Chain A, N-Terminal Domain Core Methionine Mutation 40 7e-05
pdb|1DYB| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2... 40 7e-05
pdb|1L70| Lysozyme (E.C.3.2.1.17) (Mutant With Val 131 Re... 40 7e-05
pdb|1L19| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 38 Rep... 40 7e-05
pdb|130L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|102L| Lysozyme Insertion Mutant With Ala Inserted Aft... 40 7e-05
pdb|206L| Phage T4 Lysozyme 40 7e-05
pdb|1L35| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Repl... 40 7e-05
pdb|2LZM| Lysozyme (E.C.3.2.1.17) >gi|230897|pdb|3LZM| L... 40 7e-05
pdb|1L29| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 40 7e-05
pdb|1L12| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|236L| The Response Of T4 Lysozyme To Large-To-Small S... 40 7e-05
pdb|1CUP|A Chain A, Methionine Core Mutant Of T4 Lysozyme 40 7e-05
pdb|1L42| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 16 Rep... 40 7e-05
pdb|1L09| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|1JTN|A Chain A, Alternative Structures Of A Sequence Ex... 40 7e-05
pdb|1LYG| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 7e-05
pdb|1L03| Sgamma157-Beta-Mercaptoethanol-Lysozyme (E.C.3.... 40 7e-05
pdb|171L| Lysozyme (E.C.3.2.1.17) Mutant With Glu 45 Repl... 40 7e-05
pdb|1L57| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 116 Re... 40 7e-05
pdb|167L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ile... 40 7e-05
pdb|1G07|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1L76| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 7e-05
pdb|172L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Repla... 40 7e-05
pdb|1LYF| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 7e-05
pdb|1G0K|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1G0J|A Chain A, Crystal Structure Of T4 Lysozyme Mutant... 40 7e-05
pdb|1L97|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ile... 40 7e-05
pdb|1L13| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|174L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Thr... 40 7e-05
pdb|1L81| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 7e-05
pdb|1L47| Lysozyme (E.C.3.2.1.17) (Mutant With Arg 154 Re... 40 7e-05
pdb|1L58| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 143 Re... 40 7e-05
pdb|149L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Repla... 40 7e-05
pdb|1L88| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L02| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Re... 40 7e-05
pdb|212L| Protein Structure Plasticity Exemplified By Ins... 40 7e-05
pdb|1L64| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 40 Rep... 40 7e-05
pdb|165L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 7e-05
pdb|1L31| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 40 7e-05
pdb|1L18| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Repl... 40 7e-05
pdb|1D3J|A Chain A, N-Terminal Domain Core Methionine Mutation 40 9e-05
pdb|1LYH| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 9e-05
pdb|123L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 9e-05
pdb|1L44| Lysozyme (E.C.3.2.1.17) (Mutant With Arg 119 Re... 40 9e-05
pdb|1L93| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 9e-05
pdb|1LYI| Lysozyme Mutant With Cys 54 Replaced By Thr, Th... 40 9e-05
pdb|1QSB|A Chain A, The Introduction Of Strain And Its Effe... 40 9e-05
pdb|1L26| Sgamma86-Beta-Mercaptoethanol-Lysozyme (E.C.3.2... 40 9e-05
pdb|1CV4|A Chain A, T4 Lysozyme Mutant L118m 40 9e-05
pdb|1L56| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 60 Rep... 40 9e-05
pdb|241L| The Response Of T4 Lysozyme To Large-To-Small S... 40 9e-05
pdb|1CV3|A Chain A, T4 Lysozyme Mutant L121m 40 9e-05
pdb|1L79| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 40 9e-05
pdb|1DYC| Lysozyme (E.C.3.2.1.17) Mutant With Val 131 Rep... 40 9e-05
pdb|161L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 40 9e-05
pdb|1DYD| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2... 40 9e-05
pdb|1CV5|A Chain A, T4 Lysozyme Mutant L133m 39 1e-04
pdb|1KNI|A Chain A, Stabilizing Disulfide Bridge Mutant Of ... 39 1e-04
pdb|1L84| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1L91| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1QUH|A Chain A, L99gE108V MUTANT OF T4 LYSOZYME 39 1e-04
pdb|1L00| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Rep... 39 1e-04
pdb|125L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|235L| The Response Of T4 Lysozyme To Large-To-Small S... 39 1e-04
pdb|1CU5|A Chain A, T4 Lysozyme Mutant L91m 39 1e-04
pdb|1D3F|A Chain A, N-Terminal Domain Core Methionine Mutation 39 1e-04
pdb|118L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1G1W|A Chain A, T4 Lysozyme Mutant C54tC97AQ105M 39 1e-04
pdb|1L30| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Rep... 39 1e-04
pdb|104L|A Chain A, Lysozyme Insertion Mutant With Ala, Ala... 39 1e-04
pdb|152L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Repla... 39 1e-04
pdb|1L24| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 82 Rep... 39 1e-04
pdb|163L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1D2W|A Chain A, N-Terminal Domain Core Methionine Mutation 39 1e-04
pdb|200L| Cavities, Core-Packing, Protein Stability Mol_i... 39 1e-04
pdb|158L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|162L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1G1V|A Chain A, T4 Lysozyme Mutant C54tC97AI58T 39 1e-04
pdb|1L74| Lysozyme (E.C.3.2.1.17) (Mutant With Glu 128 Re... 39 1e-04
pdb|164L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|1CVK|A Chain A, T4 Lysozyme Mutant L118a 39 1e-04
pdb|243L| The Response Of T4 Lysozyme To Large-To-Small S... 39 1e-04
pdb|1L83| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|205L| Lysozyme (E.C.3.2.1.17) Insertion Mutant With A... 39 1e-04
pdb|209L| Protein Structure Plasticity Exemplified By Ins... 39 1e-04
pdb|1CTW|A Chain A, T4 Lysozyme Mutant I78a 39 1e-04
pdb|224L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|156L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 1e-04
pdb|220L| Generating Ligand Binding Sites In T4 Lysozyme ... 39 1e-04
pdb|1QSQ|A Chain A, Cavity Creating Mutation 39 1e-04
pdb|244L| The Response Of T4 Lysozyme To Large-To-Small S... 39 1e-04
pdb|1I6S|A Chain A, T4 Lysozyme Mutant C54tC97AN101A 39 1e-04
pdb|157L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 2e-04
pdb|1L41| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 39 2e-04
pdb|147L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 2e-04
pdb|255L| Hydrolase 39 2e-04
pdb|1L23| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 77 Rep... 39 2e-04
pdb|1QT3|A Chain A, T26d Mutant Of T4 Lysozyme 39 2e-04
pdb|218L| Protein Structure Plasticity Exemplified By Ins... 39 2e-04
pdb|249L| The Response Of T4 Lysozyme To Large-To-Small S... 39 2e-04
pdb|1L45| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 135 Re... 39 2e-04
pdb|1CV0|A Chain A, T4 Lysozyme Mutant F104m 39 2e-04
pdb|1D3M|A Chain A, Methionine Core Mutation 39 2e-04
pdb|180L|B Chain B, Mol_id: 1; Molecule: Lysozyme; Chain: A... 39 2e-04
pdb|253L| Lysozyme 39 2e-04
pdb|254L| Lysozyme 39 2e-04
pdb|248L| The Response Of T4 Lysozyme To Large-To-Small S... 39 2e-04
pdb|1QT4|A Chain A, T26q Mutant Of T4 Lysozyme 39 2e-04
pdb|231L| T4 Lysozyme Mutant M106k 39 2e-04
pdb|138L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 2e-04
pdb|1QTZ|A Chain A, D20c Mutant Of T4 Lysozyme 39 2e-04
pdb|262L|A Chain A, Structural Characterisation Of An Engin... 39 2e-04
pdb|197L| Cavities, Core-Packing, Protein Stability Mol_i... 39 2e-04
pdb|139L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 2e-04
pdb|1QT7|A Chain A, E11n Mutant Of T4 Lysozyme 39 2e-04
pdb|1QT5|A Chain A, D20e Mutant Structure Of T4 Lysozyme 39 2e-04
pdb|239L| The Response Of T4 Lysozyme To Large-To-Small S... 39 2e-04
pdb|129L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 39 2e-04
pdb|173L| Lysozyme (E.C.3.2.1.17) Mutant With Lys 16 Repl... 39 2e-04
pdb|131L| Lysozyme (E.C.3.2.1.17) Mutant With Thr 26 Repl... 39 2e-04
pdb|250L| The Response Of T4 Lysozyme To Large-To-Small S... 39 2e-04
pdb|1QT6|A Chain A, E11h Mutant Of T4 Lysozyme 39 2e-04
pdb|1L54| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 39 2e-04
pdb|240L| The Response Of T4 Lysozyme To Large-To-Small S... 39 2e-04
pdb|1QT8|A Chain A, T26h Mutant Of T4 Lysozyme 39 2e-04
pdb|1L34| Lysozyme (E.C.3.2.1.17) (Mutant With Arg 96 Rep... 38 3e-04
pdb|159L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 38 3e-04
pdb|1C69|A Chain A, T4 Lysozyme Mutant C54tC97AL133A IN THE... 38 3e-04
pdb|1CU6|A Chain A, T4 Lysozyme Mutant L91a 38 3e-04
pdb|228L| Generating Ligand Binding Sites In T4 Lysozyme ... 38 3e-04
pdb|213L| Protein Structure Plasticity Exemplified By Ins... 38 3e-04
pdb|195L| Cavities, Core-Packing, Protein Stability Mol_i... 38 3e-04
pdb|144L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 38 3e-04
pdb|196L| Cavities, Core-Packing, Protein Stability Mol_i... 38 3e-04
pdb|1L55| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Rep... 38 3e-04
pdb|1EPY|A Chain A, T4 Lysozyme Mutant, T21hC54TC97AQ141HT142H 38 3e-04
pdb|1D9W|A Chain A, Bacteriophage T4 Lysozyme Mutant 38 3e-04
pdb|1QUD|A Chain A, L99g Mutant Of T4 Lysozyme 38 3e-04
pdb|1CX7|A Chain A, T4 Lysozyme Methionine Core Mutant 38 3e-04
pdb|252L| Generating Ligand Binding Sites In T4 Lysozyme ... 38 3e-04
pdb|175L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Cys... 38 3e-04
pdb|168L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Glu... 38 3e-04
pdb|1QTC|A Chain A, The Introduction Of Strain And Its Effe... 38 3e-04
pdb|229L| Generating Ligand Binding Sites In T4 Lysozyme ... 38 3e-04
pdb|214L| Protein Structure Plasticity Exemplified By Ins... 37 4e-04
pdb|141L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 37 4e-04
pdb|1LGU|A Chain A, T4 Lysozyme Mutant L99aM102Q >gi|214660... 37 4e-04
pdb|145L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 37 4e-04
pdb|146L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 37 4e-04
pdb|1QTD|A Chain A, The Introduction Of Strain And Its Effe... 37 4e-04
pdb|1L22| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 124 Re... 37 4e-04
pdb|140L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 37 6e-04
pdb|226L| Generating Ligand Binding Sites In T4 Lysozyme ... 37 6e-04
pdb|198L| Cavities, Core-Packing, Protein Stability Mol_i... 37 6e-04
pdb|1C66|A Chain A, T4 Lysozyme Mutant C54tC97AL121AL133A I... 37 6e-04
pdb|199L| Cavities, Core-Packing, Protein Stability Mol_i... 37 6e-04
pdb|143L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 37 7e-04
pdb|1B6I|A Chain A, T4 Lysozyme Mutant With Cys 54 Replaced... 36 0.001
pdb|211L| Protein Structure Plasticity Exemplified By Ins... 36 0.001
pdb|142L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Repl... 35 0.002
pdb|215L| Protein Structure Plasticity Exemplified By Ins... 35 0.002
pdb|1K28|A Chain A, The Structure Of The Bacteriophage T4 C... 35 0.003
pdb|1D3N|A Chain A, Methionine Core Mutation 33 0.006
pdb|169L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Glu... 32 0.014
pdb|1CX6|A Chain A, T4 Lysozyme Substituted With Selenometh... 32 0.018
pdb|1LPY|A Chain A, Multiple Methionine Substitutions In T4... 28 0.34
pdb|1H78|A Chain A, Structural Basis For Allosteric Substra... 26 1.3
pdb|1GKF|A Chain A, Crystal Structures Of Penicillin Acylas... 24 3.8
pdb|1GM9|A Chain A, Crystal Structures Of Penicillin Acylas... 24 3.8
pdb|1E3A|A Chain A, A Slow Processing Precursor Penicillin ... 24 3.8
pdb|1GM7|A Chain A, Crystal Structures Of Penicillin Acylas... 24 3.8
pdb|1A5I|A Chain A, Catalytic Domain Of Vampire Bat (Desmod... 24 3.8
pdb|1GM8|A Chain A, Crystal Structures Of Penicillin Acylas... 24 3.8
pdb|1LLW|A Chain A, Structural Studies On The Synchronizati... 24 3.8
pdb|1EI5|A Chain A, Crystal Structure Of A D-Aminopeptidase... 24 5.0
pdb|1KXE| Sindbis Virus Capsid (Y180s, E183g Double Muta... 23 6.5
>pdb|1L72| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Replaced By Ala, Glu
128 Replaced By Ala) (D127A,E128A)
Length = 164
Score = 43.1 bits (100), Expect = 8e-06
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +A A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWAAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L28| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Gly)
(P86G)
Length = 164
Score = 43.1 bits (100), Expect = 8e-06
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + G Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKGVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|192L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17;
Engineered: Yes; Mutation: N40a, S44a, E45a, D47a, K48a,
C54t, C97a, D127a, E128a, V131a, N132a
Length = 164
Score = 43.1 bits (100), Expect = 8e-06
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLAAAKAALAAAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +A A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWAAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AALAKSRWYNQ 141
>pdb|201L|B Chain B, Lysozyme (E.C.3.2.1.17) Insertion Mutant With His And Pro
Inserted After Lys 48, Cys 54 Replaced By Thr, Cys 97
Replaced By Ala (Ins(K48-Hp),C54t,C97a)
pdb|201L|A Chain A, Lysozyme (E.C.3.2.1.17) Insertion Mutant With His And Pro
Inserted After Lys 48, Cys 54 Replaced By Thr, Cys 97
Replaced By Ala (Ins(K48-Hp),C54t,C97a)
Length = 166
Score = 43.1 bits (100), Expect = 8e-06
Identities = 28/108 (25%), Positives = 52/108 (47%), Gaps = 9/108 (8%)
Query: 7 SPSIYTDKTG---HPTIGYGYNLSVYSYEGKRI------TKTYGLLTDILSYGWYKNLDA 57
SPS+ K+ HP IG N + E +++ G+L + Y +LDA
Sbjct: 36 SPSLNAAKSELDKHPAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDA 95
Query: 58 MRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 96 VRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 143
>pdb|1TLA| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Ser 117 Replaced By Phe)
(C54t,C97a,S117f)
Length = 164
Score = 43.1 bits (100), Expect = 8e-06
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F F++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNFLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L73| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Replaced By Ala, Glu
128 Replaced By Ala, Val 131 Replaced By Ala, Asn 132
Replaced By Ala) (D127A,E128A,V131A,N132A)
Length = 164
Score = 43.1 bits (100), Expect = 8e-06
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +A A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWAAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AALAKSRWYNQ 141
>pdb|1DYG| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2.1.17) Mutant With
Val 131 Replaced By Glu (V131e)
Length = 164
Score = 42.7 bits (99), Expect = 1e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
E L KS ++NQ
Sbjct: 131 ENLAKSRWYNQ 141
>pdb|176L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Leu 32 Replaced By
Thr, Thr 34 Replaced By Lys, Lys 35 Replaced By Val, Ser
36 Replaced By Asp, Pro 37 Replaced By Gly, Ser 38
Replaced By Asn, Leu 39 Replaced By Ser, Cys 54 Replaced
By Thr, And Cys 97 Replaced By Ala
(L32t,T34k,K35v,S36d,P37g,S38n, L39s,C54t,C97a)
pdb|176L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Leu 32 Replaced By
Thr, Thr 34 Replaced By Lys, Lys 35 Replaced By Val, Ser
36 Replaced By Asp, Pro 37 Replaced By Gly, Ser 38
Replaced By Asn, Leu 39 Replaced By Ser, Cys 54 Replaced
By Thr, And Cys 97 Replaced By Ala
(L32t,T34k,K35v,S36d,P37g,S38n, L39s,C54t,C97a)
Length = 164
Score = 42.4 bits (98), Expect = 1e-05
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLSVYSYEGKR---------------ITK---------- 38
EG IY D G+ TIG G+ L V ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHTLKVDGNSNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L59| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Thr 109 Replaced By Asn)
(C54T,C97A,T109N)
Length = 164
Score = 42.4 bits (98), Expect = 1e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G NG+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGENGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L10| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Ile)
(T157i)
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 34/148 (22%), Positives = 59/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R GIW
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRTGIW 158
>pdb|1G0P|A Chain A, Crystal Structure Of T4 Lysozyme Mutant V149g
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 30/143 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQV-KKERQGIWKF 116
L KS ++NQ + ++GI F
Sbjct: 131 VNLAKSRWYNQTPNRAKRGITTF 153
>pdb|1L01| Lysozyme (E.C.3.2.1.17) (Double Mutant With Thr 155 Replaced By
Ala And Thr 157 Replaced By Ile) (T155a,T157i)
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 34/148 (22%), Positives = 59/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R GIW
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRAGIW 158
>pdb|1LLH|A Chain A, Are Carboxy Terminii Of Helices Coded By The Local
Sequence Or By Tertiary Structure Contacts
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 34/148 (22%), Positives = 59/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R GIW
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRTGIW 158
>pdb|160L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Met 120 Replaced By Ala
(C54t,C97a,M120a)
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++A++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRALQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L51| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Replaced By Val, Val
149 Replaced By Ile, Thr 152 Replaced By Ser)
(A98V,V149I,T152S)
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 29/139 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR V++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCVLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKERQGI 113
L KS ++NQ + I
Sbjct: 131 VNLAKSRWYNQTPNRAKRI 149
>pdb|127L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Val 75
Replaced By Thr, Cys 97 Replaced By Ala (C54t,V75t,
C97a)
Length = 164
Score = 42.0 bits (97), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
T G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAATRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L15| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Val)
(T157v)
Length = 164
Score = 41.6 bits (96), Expect = 2e-05
Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R G+W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRTGVW 158
>pdb|1L49| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Replaced By Val, Thr
152 Replaced By Ser) (A98V,T152S)
Length = 164
Score = 41.6 bits (96), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR V++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCVLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QUG|A Chain A, E108v Mutant Of T4 Lysozyme
Length = 162
Score = 41.6 bits (96), Expect = 2e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G+ G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGVTGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L48| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Replaced By Val)
(A98V)
Length = 164
Score = 41.6 bits (96), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR V++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCVLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1DYA| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2.1.17) Mutant With
Val 131 Replaced By Asp (V131d)
Length = 164
Score = 41.6 bits (96), Expect = 2e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
+ L KS ++NQ
Sbjct: 131 DNLAKSRWYNQ 141
>pdb|1L50| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 98 Replaced By Val, Val
149 Replaced By Cys, Thr 152 Replaced By Ser)
(A98V,V149C,T152S)
Length = 164
Score = 41.6 bits (96), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR V++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCVLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QS9|A Chain A, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
Length = 162
Score = 41.6 bits (96), Expect = 2e-05
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR V++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAVLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|137L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By
Phe, Cys 54 Replaced By Thr And Cys 97 Replaced By Ala
(S44f, C54t, C97a)
pdb|137L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By
Phe, Cys 54 Replaced By Thr And Cys 97 Replaced By Ala
(S44f, C54t, C97a)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYEGKR---------ITK---------- 38
EG IY D G+ TIG G+ +L+ +E + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKFELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|107L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Gly, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44g,C54t,
C97a)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNL----SVYSYEGKR-----------ITK---------- 38
EG IY D G+ TIG G+ L S+ + +G+ ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKGELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L71| Lysozyme (E.C.3.2.1.17) (Mutant With Glu 128 Replaced By Ala, Val
131 Replaced By Ala) (E128A,V131A)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 ANLAKSRWYNQ 141
>pdb|247L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKAKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L75| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 127 Replaced By Ala, Glu
128 Replaced By Ala, Val 131 Replaced By Ala, Asn 132
Replaced By Ala, Leu 133 Replaced By Ala)
(D127A,E128A,V131A,N132A,L133A)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +A A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWAAAA 130
Query: 95 ERLQKSPYFNQ 105
KS ++NQ
Sbjct: 131 AAAAKSRWYNQ 141
>pdb|1L61| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 38 Replaced By Asn, Cys
54 Replaced By Thr, Cys 97 Replaced By Ala)
(S38N,C54T,C97A)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 34/131 (25%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYEGKR---------ITK---------- 38
EG IY D G+ TIG G+ NL+ E + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPNLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|238L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++++ +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMAFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L11| Sgamma97-Beta-Mercaptoethanol-Lysozyme (E.C.3.2.1.17) (Mutant With
Thr 157 Replaced By Leu) (T157l)
Length = 164
Score = 41.2 bits (95), Expect = 3e-05
Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R G+W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRTGLW 158
>pdb|1L25| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Ala)
(P86A)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKAVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|216L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By
Trp, Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(S44w, C54t, C97a)
pdb|216L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By
Trp, Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(S44w, C54t, C97a)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYEGKR---------ITK---------- 38
EG IY D G+ TIG G+ +L+ +E + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKWELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L38| Lysozyme (E.C.3.2.1.17) (Mutant With Gln 123 Replaced By Glu)
(Q123E)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ +++K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQEKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L21| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 55 Replaced By Gly)
(N55G)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 34/131 (25%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYE---------GKRITK---------- 38
EG IY D G+ TIG G+ +L+ E G ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCGGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|191L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17;
Engineered: Yes; Mutation: N53a, N55a, V57a, E128a,
V131a, N132a
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRACAGAITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AALAKSRWYNQ 141
>pdb|1DYE| Lysozyme (E.C.3.2.1.17) Mutant With Val 131 Replaced By Ser
(V131s)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 SNLAKSRWYNQ 141
>pdb|1L77| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Met 102 Replaced By Leu)
(C54t,C97a,M102l)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++L + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINLVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L32| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Ser)
(P86S)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKSVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L37| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 115 Replaced By Glu)
(T115E)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F+ ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFENSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L36| Lysozyme (E.C.3.2.1.17) Mutant With Glu 128 Replaced By Ala, Val
131 Replaced By Ala, Asn 132 Replaced By Ala (E128a,
V131a, N132a) (Three Alanine Substitutions)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDAAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AALAKSRWYNQ 141
>pdb|177L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Asp 127 Replaced By Cys, Arg 154
Replaced By Cys (C54t,C97a,D127c,R154c)
pdb|178L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Asp 127 Replaced By Cys, Arg 154
Replaced By Cys (C54t,C97a,D127c,R154c)
pdb|179L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Ala, Cys 97
Replaced By Ala, Asp 127 Replaced By Cys, Arg 154
Replaced By Cys (C54a,C97a,D127c,R154c)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWCEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L67| Lysozyme (E.C.3.2.1.17) (Mutant With Leu 46 Replaced By Ala, Cys
54 Replaced By Thr, Cys 97 Replaced By Ala)
(L46A,C54T,C97A)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYEGKR---------ITK---------- 38
EG IY D G+ TIG G+ +L+ E + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSEADKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L92| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ile (C54t,C97a,
L99i)
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR I+++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAIINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|234L| T4 Lysozyme Mutant M106l
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + LG G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQLGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CU3|A Chain A, T4 Lysozyme Mutant V87m
Length = 164
Score = 40.8 bits (94), Expect = 4e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPMYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L27| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Asp)
(P86D)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKDVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L39| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Asn 144 Replaced By Glu)
(C54T,C97A,N144E)
pdb|1L40| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Asn 144 Replaced By Glu)
(C54T,C97A,N144E)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/139 (21%), Positives = 58/139 (41%), Gaps = 29/139 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKERQGI 113
L KS ++NQ + + +
Sbjct: 131 VNLAKSRWYNQTPERAKRV 149
>pdb|128L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Val 87
Replaced By Thr, Cys 97 Replaced By Ala (C54t,V87t,
C97a)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPTYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L33| Lysozyme (E.C.3.2.1.17) (Mutant With Val 131 Replaced By Ala)
(V131A)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 ANLAKSRWYNQ 141
>pdb|1L80| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Leu 99 Replaced By Phe, Met 102
Replaced By Leu And Val 111 Replaced By Ile)
(C54t,C97a,L99f,M102l,V111i)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 31/131 (23%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++L + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAFINLVFQMGETGIAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|119L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Ala 134 Replaced By Ser (C54t,C97a,
A134s)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLSKSRWYNQ 141
>pdb|246L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRITK-- 38
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLANQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CV1|A Chain A, T4 Lysozyme Mutant V111m
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGMAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CUQ|A Chain A, T4 Lysozyme Mutant V103m
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMMFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L82| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Leu 99 Replaced By Phe, Met 102
Replaced By Leu, Val 111 Replaced By Ile, And Phe 153
Replaced By Leu) (C54t,C97a,L99f,M102l,V111i,F153l)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 31/131 (23%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++L + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAFINLVFQMGETGIAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QTB|A Chain A, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
Length = 162
Score = 40.4 bits (93), Expect = 5e-05
Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNL-------SVYSYEGKRITK------------------ 38
EG IY D G+ TIG G+ L +V S K I +
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAVKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYE| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Val, Cys 97 Replaced By Ala (C54t,T59v,C97a)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVIVKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|210L| Protein Structure Plasticity Exemplified By Insertion And Deletion
Mutants In T4 Lysozyme
Length = 163
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 28/130 (21%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKR----- 35
EG IY D G+ TIG G+ L+ + E ++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 36 ITKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVE 95
+ G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAV 130
Query: 96 RLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 NLAKSRWYNQ 140
>pdb|1L94| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Val (C54t,C97a,
L99v)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAVINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|2L78| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Val 111 Replaced By Ile)
(C54t,C97a,V111i)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGIAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|103L| Phage T4 Lysozyme Insertion Mutant With Ser, Leu, And Asp Inserted
After Asn 40, Cys 54 Replaced By Thr, Cys 97 Replaced By
Ala, (Ins(N40-Sld),C54t,C97a)
Length = 167
Score = 40.4 bits (93), Expect = 5e-05
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 32/134 (23%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNL----SVYSYEGKR--------------ITK------- 38
EG IY D G+ TIG G+ L S+ S + + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNSLDAAKSELDKAIGRNTNGVITKDEAEKLF 70
Query: 39 -------TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYA 91
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +
Sbjct: 71 NQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWD 130
Query: 92 LAVERLQKSPYFNQ 105
A L KS ++NQ
Sbjct: 131 EAAVNLAKSRWYNQ 144
>pdb|1L46| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 147 Replaced By Glu)
(K147E)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/139 (21%), Positives = 57/139 (40%), Gaps = 29/139 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKERQGI 113
L KS ++NQ + +
Sbjct: 131 VNLAKSRWYNQTPNRAERV 149
>pdb|122L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Ala 73
Replaced By Ser, Cys 97 Replaced By Ala (C54t,A73s,
C97a)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
+ G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDSAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QS5|A Chain A, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
Length = 162
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRALLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L62| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Thr 109 Replaced By Asp)
(C54T,C97A,T109D)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G +G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGEDGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|189L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Leu, Ser 38
Replaced By Asp, Ala 41 Replaced By Val, Ala 82 Pro, Asn
116 Replaced By Asp, Val 131 Replaced By Ala, And Asn
144 Replaced By Asp Substitutions (I3l,S38d,A41v,
A82p,N116d,V131a,N144d)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 34/131 (25%), Positives = 57/131 (42%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY------NLSVYSYEGKR---------ITK---------- 38
EG IY D G+ TIG G+ +L+V E + ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPDLNVAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNPKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTDSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 ANLAKSRWYNQ 141
>pdb|1QTH|A Chain A, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
pdb|1QTH|B Chain B, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 56/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAMLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QUO|A Chain A, L99aE108V MUTANT OF T4 LYSOZYME
Length = 162
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G+ G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAAINMVFQMGVTGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0Q|A Chain A, Crystal Structure Of T4 Lysozyme Mutant V149i
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 31/139 (22%), Positives = 57/139 (40%), Gaps = 29/139 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKERQGI 113
L KS ++NQ + I
Sbjct: 131 VNLAKSRWYNQTPNRAKRI 149
>pdb|1L60| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 113 Replaced By Ala)
(G113A)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAAFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1C61|A Chain A, T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM
Krypton
pdb|1C60|A Chain A, T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM
Argon
pdb|1L85| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Phe 153 Replaced By Ala (C54t,C97a,
F153a)
pdb|1C62|A Chain A, T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM
Xenon
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ--------VKKERQGIW 114
L KS ++NQ + R G W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTARTGTW 158
>pdb|221L| Lysozyme (E.C.3.2.1.17) Mutant With Ala 49 Replaced By Ser, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (A49s,C54t,
C97a)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNL---------------SVYSYEGKRITK---------- 38
EG IY D G+ TIG G+ L S+ ITK
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKSIGRNTNGVITKDEAEKLFNQD 70
Query: 39 ----TYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L07| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Phe)
(T157f)
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 33/148 (22%), Positives = 58/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKE--------RQGIW 114
L KS ++NQ R G W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTFRTGFW 158
>pdb|1CU2|A Chain A, T4 Lysozyme Mutant L84m
Length = 164
Score = 40.4 bits (93), Expect = 5e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKMKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L68| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 44 Replaced By Ala, Cys
54 Replaced By Thr, Cys 97 Replaced By Ala)
(S44A,C54T,C97A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKAELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L86| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Phe 153 Replaced By Ile (C54t,C97a,
F153i)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|217L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Glu, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44e,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKEELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|108L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Ile, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44i,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKIELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1DYF| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2.1.17) Mutant With
Val 131 Replaced By Met (V131m)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 MNLAKSRWYNQ 141
>pdb|109L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Lys, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44k,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKKELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|110L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Leu, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44l,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKLELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|111L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Asn, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44n,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKNELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|112L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Pro, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44p,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKPELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L17| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Replaced By Val) (I3V)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|113L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Arg, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44r,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKRELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|219L| Protein Structure Plasticity Exemplified By Insertion And Deletion
Mutants In T4 Lysozyme
pdb|1L63| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala) (C54T,C97A)
pdb|1C6Q|A Chain A, T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM
Krypton
pdb|1C6P|A Chain A, T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM ARGON
pdb|1C6T|A Chain A, T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM XENON
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|114L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Thr, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44t,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKTELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|115L| Lysozyme (E.C.3.2.1.17) Mutant With Ser 44 Replaced By Val, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (S44v,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKVELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L16| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 156 Replaced By Asp)
(G156d)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0M|A Chain A, Crystal Structure Of T4 Lysozyme Mutant T152i
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|258L|A Chain A, An Adaptable Metal-Binding Site Engineered Into T4
Lysozyme
pdb|260L|A Chain A, An Adaptable Metal-Binding Site Engineered Into T4
Lysozyme
pdb|257L|A Chain A, An Adaptable Metal-Binding Site Engineered Into T4
Lysozyme
pdb|259L|A Chain A, An Adaptable Metal-Binding Site Engineered Into T4
Lysozyme
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDHEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|256L| Bacteriophage T4 Lysozyme
pdb|150L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Met 6 Replaced By Ile
(M6i)
pdb|150L|C Chain C, Lysozyme (E.C.3.2.1.17) Mutant With Met 6 Replaced By Ile
(M6i)
pdb|150L|D Chain D, Lysozyme (E.C.3.2.1.17) Mutant With Met 6 Replaced By Ile
(M6i)
pdb|150L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Met 6 Replaced By Ile
(M6i)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|237L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L04| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Asp)
(T157d)
pdb|1L05| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Asp)
(T157d)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CU0|A Chain A, T4 Lysozyme Mutant I78m
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGMLRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|233L| T4 Lysozyme Mutant M120l
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRLLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L20| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 144 Replaced By Asp)
(N144D)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|126L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Val 149 Replaced By Thr (C54t,C97a,
V149t)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L14| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Ser)
(T157s)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CV6|A Chain A, T4 Lysozyme Mutant V149m
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0L|A Chain A, Crystal Structure Of T4 Lysozyme Mutant T152v
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L87| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Phe 153 Replaced By Leu (C54t,C97a,
F153l)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L08| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Gly)
(T157g)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|242L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAAGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|232L| T4 Lysozyme Mutant M120k
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRKLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L53| Lysozyme (E.C.3.2.1.17) (Mutant With Val 149 Replaced By Cys)
(V149C)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0G|A Chain A, Crystal Structure Of T4 Lysozyme Mutant T152a
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L65| Lysozyme (E.C.3.2.1.17) (Mutant With Asp 47 Replaced By Ala, Cys
54 Replaced By Thr, Cys 97 Replaced By Ala)
(D47A,C54T,C97A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELAKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L98| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Replaced By Glu
(Q105e)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFEMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|190L| Mol_id: 1; Molecule: Lysozyme; Chain: Null; Ec: 3.2.1.17;
Engineered: Yes; Mutation: N53a, N55a, V57a
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRACAGAITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|170L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Ser, Cys 97
Replaced By Ser, Ala 146 Replaced By Cys (C54s,C97s,
A146c)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNSNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRSALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L66| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 43 Replaced By Ala, Cys
54 Replaced By Thr, Cys 97 Replaced By Ala)
(K43A,C54T,C97A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAASELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G06|A Chain A, Crystal Structure Of T4 Lysozyme Mutant V149s
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L52| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 152 Replaced By Ser)
(T152S)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|155L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Thr 115 Replaced By Ala, Ser 117
Replaced By Ala (C54t,C97a,T115a,S117a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFANALRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L99| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Replaced By Gly
(Q105g)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFGMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYJ| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Ala, Cys 97 Replaced By Ala (C54t,T59a,C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVIAKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L95| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Phe 153 Replaced By Val (C54t,C97a,
F153v)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|245L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1JQU|A Chain A, Are Carboxy Terminii Of Helices Coded By The Local
Sequence Or By Tertiary Structure Contacts
pdb|1JQU|B Chain B, Are Carboxy Terminii Of Helices Coded By The Local
Sequence Or By Tertiary Structure Contacts
pdb|1JQU|C Chain C, Are Carboxy Terminii Of Helices Coded By The Local
Sequence Or By Tertiary Structure Contacts
pdb|1JQU|D Chain D, Are Carboxy Terminii Of Helices Coded By The Local
Sequence Or By Tertiary Structure Contacts
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L06| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Glu)
(T157e)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|166L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Thr 115 Replaced By Ala
(C54t,C97a,T115a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFANSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|120L| Lysozyme (E.C.3.2.1.17) Mutant With Ala 41 Replaced By Ser, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (A41s,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNSAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|230L| T4 Lysozyme Mutant M6l
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|151L| Lysozyme (E.C.3.2.1.17) Mutant With Thr 34, Lys 35, Ser 36 And Pro
37 Replaced By Alanine (T34a,K35a,S36a,P37a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLAAAASLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1D2Y|A Chain A, N-Terminal Domain Core Methionine Mutation
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAMGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1DYB| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2.1.17) Mutant With
Val 131 Replaced By Gly (V131g)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 GNLAKSRWYNQ 141
>pdb|1L70| Lysozyme (E.C.3.2.1.17) (Mutant With Val 131 Replaced By Ala, Asn
132 Replaced By Ala) (V131A,N132A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AALAKSRWYNQ 141
>pdb|1L19| Lysozyme (E.C.3.2.1.17) (Mutant With Ser 38 Replaced By Asp)
(S38D)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPDLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|130L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Thr 151 Replaced By Ser (C54t,C97a,
T151s)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|102L| Lysozyme Insertion Mutant With Ala Inserted After Asn 40, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (Ins(N40-A),
C54t,C97a)
Length = 165
Score = 40.0 bits (92), Expect = 7e-05
Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 30/132 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGY--------NLSVYSYEGKRITKTY--------------- 40
EG IY D G+ TIG G+ N + S K I +
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAAKSELDKAIGRNTNGVITKDEAEKLFNQ 70
Query: 41 -------GLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALA 93
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 DVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEA 130
Query: 94 VERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 AVNLAKSRWYNQ 142
>pdb|206L| Phage T4 Lysozyme
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNASKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L35| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Replaced By Tyr, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala, Ile 9 Replaced
By Cys, And Leu 164 Replaced By Cys) (C54T, C97a, I9c,
And L164c)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|2LZM| Lysozyme (E.C.3.2.1.17)
pdb|3LZM| Lysozyme (E.C.3.2.1.17)
pdb|1LYD| T4-Lysozyme
pdb|4LZM| Lysozyme (E.C.3.2.1.17) (High Salt)
pdb|5LZM| Lysozyme (E.C.3.2.1.17) (Medium Salt)
pdb|6LZM| Lysozyme (E.C.3.2.1.17) (Low Salt)
pdb|7LZM| Lysozyme (E.C.3.2.1.17) (Dithiothreitol)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L29| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By His)
(P86H)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKHVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L12| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Asn)
(T157n)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|236L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPAYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CUP|A Chain A, Methionine Core Mutant Of T4 Lysozyme
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALMNMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L42| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 16 Replaced By Glu)
(K16E)
pdb|1L43| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 16 Replaced By Glu)
(K16E)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLEIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L09| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By His)
(T157h)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1JTN|A Chain A, Alternative Structures Of A Sequence Extended T4 Lysozyme
Show That The Highly Conserved Beta-Sheet Region Has
Weak Intrinsic Folding Propensity
pdb|1JTN|B Chain B, Alternative Structures Of A Sequence Extended T4 Lysozyme
Show That The Highly Conserved Beta-Sheet Region Has
Weak Intrinsic Folding Propensity
pdb|1JTM|A Chain A, Alternative Structures Of A Sequence Extended T4 Lysozyme
Show That The Highly Conserved Beta-Sheet Has Weak
Intrinsic Folding Propensity
Length = 178
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYG| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Asn, Cys 97 Replaced By Ala (C54t,T59n,C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVINKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L03| Sgamma157-Beta-Mercaptoethanol-Lysozyme (E.C.3.2.1.17) (Mutant
With Thr 157 Replaced By Cys) (T157c)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|171L| Lysozyme (E.C.3.2.1.17) Mutant With Glu 45 Replaced By Ala, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (E45a,C54t,
C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSALDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L57| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 116 Replaced By Asp)
(N116D)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTDSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|167L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Cys,
Ile 9 Replaced By Cys, Cys 54 Replaced By Thr, Leu 164
Replaced By Cys (I3c,I9c,C54t,L164c)
pdb|167L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Cys,
Ile 9 Replaced By Cys, Cys 54 Replaced By Thr, Leu 164
Replaced By Cys (I3c,I9c,C54t,L164c)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G07|A Chain A, Crystal Structure Of T4 Lysozyme Mutant V149c
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L76| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Asp
72 Replaced By Pro, Cys 97 Replaced By Ala)
(C54T,D72P,C97A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VPAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|172L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Cys (I3c)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYF| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Ser, Cys 97 Replaced By Ala (C54t,T59s,C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVISKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0K|A Chain A, Crystal Structure Of T4 Lysozyme Mutant T152c
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G0J|A Chain A, Crystal Structure Of T4 Lysozyme Mutant T152s
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L97|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Pro
(I3p) (Space Group P 21 21 2)
pdb|1L97|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Pro
(I3p) (Space Group P 21 21 2)
pdb|1L96| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Pro (I3p)
(Space Group P 32 2 1)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L13| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Arg)
(T157r)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|174L|A Chain A, Lysozyme (E.C.3.2.1.17) Mutant With Thr 34 Replaced By
Ala, Lys 35 Replaced By Ala, Ser 36 Replaced By Ala, Pro
37 Replaced By Ala, Ser 38 Replaced By Asp, Asn 40
Replaced By Ala, Ser 44 Replaced By Ala, Glu 45 Replaced
By Ala, Asp 47 Replaced By Ala, Lys 48 Replaced By Ala,
Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(T34a,K35a,S36a,P37a,S38d,N40a,
S44a,E45a,D47a,K48a,C54t,C97a)
pdb|174L|B Chain B, Lysozyme (E.C.3.2.1.17) Mutant With Thr 34 Replaced By
Ala, Lys 35 Replaced By Ala, Ser 36 Replaced By Ala, Pro
37 Replaced By Ala, Ser 38 Replaced By Asp, Asn 40
Replaced By Ala, Ser 44 Replaced By Ala, Glu 45 Replaced
By Ala, Asp 47 Replaced By Ala, Lys 48 Replaced By Ala,
Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(T34a,K35a,S36a,P37a,S38d,N40a,
S44a,E45a,D47a,K48a,C54t,C97a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLAAAADLAAAKAALAAAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L81| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Leu 99 Replaced By Phe, Met 102
Replaced By Leu, And Phe 153 Replaced By Leu)
(C54t,C97a,L99f,M102l,F153l)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 31/131 (23%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++L + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAFINLVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L47| Lysozyme (E.C.3.2.1.17) (Mutant With Arg 154 Replaced By Glu)
(R154E)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L58| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 143 Replaced By Ala)
(P143A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|149L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Leu (I3l)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L88| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Phe 153 Replaced By Met (C54t,C97a,
F153m)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L02| Lysozyme (E.C.3.2.1.17) (Mutant With Thr 157 Replaced By Ala)
(T157a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|212L| Protein Structure Plasticity Exemplified By Insertion And Deletion
Mutants In T4 Lysozyme
Length = 168
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L64| Lysozyme (E.C.3.2.1.17) (Mutant With Asn 40 Replaced By Ala, Lys
43 Replaced By Ala, Ser 44 Replaced By Ala, Glu 45
Replaced By Ala, Leu 46 Replaced By Ala, Asp 47 Replaced
By Ala, Lys 48 Replaced By Ala, Cys 54 Replaced By Thr,
Cys 97 Replaced By Ala) (N40A,K43A,S44A,E45A,
L46A,D47A,K48A,C54T,C97A)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLAAAAAAAAAAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|165L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Ser 117 Replaced By Ala
(C54t,C97a,S117a)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNALRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L31| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Arg)
(P86R)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKRVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L18| Lysozyme (E.C.3.2.1.17) (Mutant With Ile 3 Replaced By Tyr) (I3Y)
Length = 164
Score = 40.0 bits (92), Expect = 7e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1D3J|A Chain A, N-Terminal Domain Core Methionine Mutation
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKMFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYH| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Gly, Cys 97 Replaced By Ala (C54t,T59g,C97a)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVIGKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|123L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Ala 82
Replaced By Ser, Cys 97 Replaced By Ala (C54t,A82s,
C97a)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNSKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L44| Lysozyme (E.C.3.2.1.17) (Mutant With Arg 119 Replaced By Glu)
(R119E)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLEMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L93| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Met (C54t,C97a,
L99m)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAMINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1LYI| Lysozyme Mutant With Cys 54 Replaced By Thr, Thr 59 Replaced By
Asp, Cys 97 Replaced By Ala (C54t,T59d,C97a)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVIDKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QSB|A Chain A, The Introduction Of Strain And Its Effects On The
Structure And Stability Of T4 Lysozyme
Length = 162
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRACLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L26| Sgamma86-Beta-Mercaptoethanol-Lysozyme (E.C.3.2.1.17) (Mutant With
Pro 86 Replaced By Cys) (P86C)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKCVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CV4|A Chain A, T4 Lysozyme Mutant L118m
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSMRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L56| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 60 Replaced By Pro)
(K60P)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITPDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|241L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGAGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CV3|A Chain A, T4 Lysozyme Mutant L121m
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMMQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L79| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Leu 99 Replaced By Phe, Val 111
Replaced By Ile) (C54t,C97a,L99f,V111i)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAFINMVFQMGETGIAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1DYC| Lysozyme (E.C.3.2.1.17) Mutant With Val 131 Replaced By Ile
(V131i)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 INLAKSRWYNQ 141
>pdb|161L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Asn 116 Replaced By Ala
(C54t,C97a,N116a)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTASLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1DYD| Sgamma97-Beta-Mercaptoethanol Lysozyme (E.C.3.2.1.17) Mutant With
Val 131 Replaced By Leu (V131l)
Length = 164
Score = 39.7 bits (91), Expect = 9e-05
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 LNLAKSRWYNQ 141
>pdb|1CV5|A Chain A, T4 Lysozyme Mutant L133m
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
+ KS ++NQ
Sbjct: 131 VNMAKSRWYNQ 141
>pdb|1KNI|A Chain A, Stabilizing Disulfide Bridge Mutant Of T4 Lysozyme
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDCEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L84| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala, Phe 153
Replaced By Ala (C54t,C97a,L99a,F153a) Complex With
Benzene
pdb|1C6L|A Chain A, T4 Lysozyme Mutant C54tC97AL99AF153A IN THE PRESENCE OF 8
Atm Argon
pdb|1L89| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala, Phe 153
Replaced By Ala (C54t,C97a,L99a,F153a)
pdb|1C6M|A Chain A, T4 Lysozyme Mutant C54tC97AL99AF153A IN THE PRESENCE OF 8
Atm Krypton
pdb|1C6N|A Chain A, T4 Lysozyme Mutant C54tC97AL99AF153A IN THE PRESENCE OF 8
Atm Xenon
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 33/148 (22%), Positives = 58/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAAINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ--------VKKERQGIW 114
L KS ++NQ + R G W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTARTGTW 158
>pdb|1L91| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Phe (C54t,C97a,
L99f)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAFINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QUH|A Chain A, L99gE108V MUTANT OF T4 LYSOZYME
Length = 162
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G+ G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAGINMVFQMGVTGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L00| Lysozyme (E.C.3.2.1.17) Mutant With Gln 105 Replaced By Ala
(Q105a)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFAMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|125L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Ala 98 Replaced By Ser (C54t,C97a,
A98s)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRASLINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|235L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGAAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CU5|A Chain A, T4 Lysozyme Mutant L91m
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y ++DA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSMDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1D3F|A Chain A, N-Terminal Domain Core Methionine Mutation
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVMTKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|118L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Ala 130 Replaced By Ser (C54t,C97a,
A130s)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAS 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G1W|A Chain A, T4 Lysozyme Mutant C54tC97AQ105M
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFMMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L30| Lysozyme (E.C.3.2.1.17) (Mutant With Pro 86 Replaced By Leu)
(P86L)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKLVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|104L|A Chain A, Lysozyme Insertion Mutant With Ala, Ala Inserted After Ser
44, Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(Ins(S44-Aa),C54t,C97a)
pdb|104L|B Chain B, Lysozyme Insertion Mutant With Ala, Ala Inserted After Ser
44, Cys 54 Replaced By Thr, Cys 97 Replaced By Ala
(Ins(S44-Aa),C54t,C97a)
Length = 166
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/133 (22%), Positives = 55/133 (40%), Gaps = 31/133 (23%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-------------------------VYSYEGKRI-- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSAAELDKAIGRNTNGVITKDEAEKLFN 70
Query: 37 ----TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYAL 92
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +
Sbjct: 71 QDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDE 130
Query: 93 AVERLQKSPYFNQ 105
A L KS ++NQ
Sbjct: 131 AAVNLAKSRWYNQ 143
>pdb|152L| Lysozyme (E.C.3.2.1.17) Mutant With Ile 3 Replaced By Cys, Ile 9
Replaced By Cys, Thr 21 Replaced By Cys, Cys 54 Replaced
By Thr, Thr 142 Replaced By Cys, And Leu 164 Replaced By
Cys (I3c,I9c,T21c,C54t,T142c,L164c)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDCEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L24| Lysozyme (E.C.3.2.1.17) (Mutant With Ala 82 Replaced By Pro)
(A82P)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNPKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|163L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Gln 123 Replaced By Ala
(C54t,C97a,Q123a)
Length = 164
Score = 39.3 bits (90), Expect = 1e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQAKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1D2W|A Chain A, N-Terminal Domain Core Methionine Mutation
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ T+G G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTMGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|200L| Cavities, Core-Packing, Protein Stability Mol_id: 1; Molecule:
Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes;
Mutation: C54t, C97a, L121a
pdb|1C64|A Chain A, T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM
Krypton
pdb|1C65|A Chain A, T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM
Xenon
pdb|1C63|A Chain A, T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM
Argon
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ + K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMAQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|158L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Ser 117 Replaced By Ala, Arg 119
Replaced By Ala (C54t,C97a,S117a,R119a)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F + ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNALAMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|162L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Gln 122 Replaced By Ala
(C54t,C97a,Q122a)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ + K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLAQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1G1V|A Chain A, T4 Lysozyme Mutant C54tC97AI58T
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVTTKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L74| Lysozyme (E.C.3.2.1.17) (Mutant With Glu 128 Replaced By Ala, Val
131 Replaced By Ala, Asn 132 Replaced By Ala, Leu 133
Replaced By Ala) (E128A,V131A,N132A,L133A)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDAAA 130
Query: 95 ERLQKSPYFNQ 105
KS ++NQ
Sbjct: 131 AAAAKSRWYNQ 141
>pdb|164L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Arg 119 Replaced By Ala
(C54t,C97a,R119a)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F + ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLAMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1CVK|A Chain A, T4 Lysozyme Mutant L118a
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F + ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSARMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|243L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVATKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L83| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,
L99a) Complex With Benzene
pdb|1L90| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,
L99a)
pdb|181L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With Benzene
pdb|182L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With Benzofuran
pdb|183L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With Indene
pdb|184L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With Isobutylbenzene
pdb|185L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With Indole
pdb|186L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With N-Butylbenzene
pdb|187L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With P-Xylene
pdb|188L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 99 Replaced By Ala (C54t,C97a,L99a)
Complexed With O-Xylene
pdb|1NHB| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, And Leu 99 Replaced By Ala
(C54t,C97a,L99a) (L99a Binding Site Is Occupied By
Ethylbenzene)
pdb|1C6H|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 4 ATM
Xenon
pdb|1C6J|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 8 ATM
Krypton
pdb|1C6K|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 8 ATM
Xenon
pdb|1C6E|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 2 ATM
Xenon
pdb|1C6G|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 4 ATM
Krypton
pdb|1C6I|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 8 ATM
Argon
pdb|1C6D|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 16 ATM
Krypton
pdb|1C6F|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 32 ATM
Argon
pdb|1C6C|A Chain A, T4 Lysozyme Mutant C54tC97AL99A IN THE PRESENCE OF 16 ATM
Argon
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAAAINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|205L| Lysozyme (E.C.3.2.1.17) Insertion Mutant With Ala Ala Ala Inserted
After Ser 44, Cys 54 Replaced By Thr, Cys 97 Replaced By
Ala (Ins(S44-Aaa),C54t,C97a)
Length = 167
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/134 (22%), Positives = 55/134 (40%), Gaps = 32/134 (23%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS--------------------------VYSYEGKRI- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSAAAELDKAIGRNTNGVITKDEAEKLF 70
Query: 37 -----TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYA 91
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +
Sbjct: 71 NQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWD 130
Query: 92 LAVERLQKSPYFNQ 105
A L KS ++NQ
Sbjct: 131 EAAVNLAKSRWYNQ 144
>pdb|209L| Protein Structure Plasticity Exemplified By Insertion And Deletion
Mutants In T4 Lysozyme
Length = 167
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/134 (22%), Positives = 55/134 (40%), Gaps = 32/134 (23%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 -----TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYA 91
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +
Sbjct: 71 VDAAAAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWD 130
Query: 92 LAVERLQKSPYFNQ 105
A L KS ++NQ
Sbjct: 131 EAAVNLAKSRWYNQ 144
>pdb|1CTW|A Chain A, T4 Lysozyme Mutant I78a
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGALRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|224L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Ala 93
Replaced By Ser, Cys 97 Replaced By Ala (C54t,A93s,
C97a)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LD++RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDSVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|156L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Thr 115 Replaced By Ala, Arg 119
Replaced By Ala (C54t,C97a,T115a,R119a)
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F + ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFANSLAMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|220L| Generating Ligand Binding Sites In T4 Lysozyme Using
Deficiency-Creating Substitutions
pdb|222L| Generating Ligand Binding Sites In T4 Lysozyme Using
Deficiency-Creating Substitutions
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINAVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QSQ|A Chain A, Cavity Creating Mutation
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQAGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|244L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR + ++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALANMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1I6S|A Chain A, T4 Lysozyme Mutant C54tC97AN101A
Length = 164
Score = 38.9 bits (89), Expect = 1e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++ + + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALIAMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|157L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Thr 115 Replaced By Ala, Asn 116
Replaced By Ala, Ser 117 Replaced By Ala, Arg 119
Replaced By Ala, Met 120 Replaced By Ala, Gln 122
Replaced By Ala, Gln 123 Replaced By Ala
(C54t,C97a,T115a,N116a,S117a,R119a, M120a,Q122a,Q123a)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 31/131 (23%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F + A+ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFAAALAALAAKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1L41| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Lys
83 Replaced By His, Cys 97 Replaced By Ala, Ala 112
Replaced By Asp) (C54T,K83H,C97A,A112D)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAHLKPVYDSLDAVRRAALINMVFQMGETGVDGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|147L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Cys 97
Replaced By Ala, Leu 121 Replaced By Met, Leu 133
Replaced By Val, Phe 153 Replaced By Leu (C54t,C97a,
L121m,L133v,F153l)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMMQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
+ KS ++NQ
Sbjct: 131 VNVAKSRWYNQ 141
>pdb|255L| Hydrolase
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1L23| Lysozyme (E.C.3.2.1.17) (Mutant With Gly 77 Replaced By Ala)
(G77A)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1QT3|A Chain A, T26d Mutant Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|218L| Protein Structure Plasticity Exemplified By Insertion And Deletion
Mutants In T4 Lysozyme
Length = 165
Score = 38.5 bits (88), Expect = 2e-04
Identities = 31/132 (23%), Positives = 56/132 (41%), Gaps = 30/132 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNY-ALA 93
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 94 VERLQKSPYFNQ 105
V L KS ++NQ
Sbjct: 131 VANLAKSRWYNQ 142
>pdb|249L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1L45| Lysozyme (E.C.3.2.1.17) (Mutant With Lys 135 Replaced By Glu)
(K135E)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L +S ++NQ
Sbjct: 131 VNLAESRWYNQ 141
>pdb|1CV0|A Chain A, T4 Lysozyme Mutant F104m
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVMQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1D3M|A Chain A, Methionine Core Mutation
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y ++DA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKMKPVYDSMDAVRRAAMINMVFQMGETGVAGFTNSMRMMQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|180L|B Chain B, Mol_id: 1; Molecule: Lysozyme; Chain: A, B; Ec: 3.2.1.17;
Engineered: Yes; Mutation: T26e, C54t, C97a; Mol_id: 2;
Molecule: Substrate Cleaved From Cell Wall Of
Escherichia Coli; Chain: C, D; Other_details: No
Coordinates Are Present For The Cell Wall Substrate
pdb|1QTV|A Chain A, T26e Apo Structure Of T4 Lysozyme
pdb|148L|E Chain E, Lysozyme (E.C.3.2.1.17) Mutant With Thr 26 Replaced By
Glu, Cys 54 Replaced By Thr, And Cys 97 Replaced By Ala
(T26e,C54t,C97a) Complexed With Substrate Cleaved From
Cell Wall Of Escherichia Coli
pdb|180L|A Chain A, Mol_id: 1; Molecule: Lysozyme; Chain: A, B; Ec: 3.2.1.17;
Engineered: Yes; Mutation: T26e, C54t, C97a; Mol_id: 2;
Molecule: Substrate Cleaved From Cell Wall Of
Escherichia Coli; Chain: C, D; Other_details: No
Coordinates Are Present For The Cell Wall Substrate
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|253L| Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|254L| Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|248L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1QT4|A Chain A, T26q Mutant Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|231L| T4 Lysozyme Mutant M106k
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQKGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|138L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Ala 93
Replaced By Cys, Cys 97 Replaced By Ala (C54t,A93c,C97a)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LD +RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDCVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QTZ|A Chain A, D20c Mutant Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|262L|A Chain A, Structural Characterisation Of An Engineered Tandem Repeat
Contrasts The Importance Of Context And Sequence In
Protein Folding
pdb|262L|B Chain B, Structural Characterisation Of An Engineered Tandem Repeat
Contrasts The Importance Of Context And Sequence In
Protein Folding
pdb|261L|A Chain A, Structural Characterisation Of An Engineered Tandem Repeat
Contrasts The Importance Of Context And Sequence In
Protein Folding
Length = 173
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 99 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 152
>pdb|197L| Cavities, Core-Packing, Protein Stability Mol_id: 1; Molecule:
Lysozyme; Chain: Null; Ec: 3.2.1.17; Engineered: Yes;
Mutation: C54t, C97a, A129m, F153a
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 32/148 (21%), Positives = 58/148 (38%), Gaps = 37/148 (25%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K +
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEMA 130
Query: 95 ERLQKSPYFNQ--------VKKERQGIW 114
L KS ++NQ + R G W
Sbjct: 131 VNLAKSRWYNQTPNRAKRVITTARTGTW 158
>pdb|139L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Asn 68
Replaced By Cys, Ala 93 Replaced By Cys, Cys 97 Replaced
By Ala (C54t,N68c,A93c,C97a)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFCQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LD +RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDCVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QT7|A Chain A, E11n Mutant Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1QT5|A Chain A, D20e Mutant Structure Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|239L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|129L| Lysozyme (E.C.3.2.1.17) Mutant With Cys 54 Replaced By Thr, Ala 93
Replaced By Thr, Cys 97 Replaced By Ala (C54t,A93t,
C97a)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/131 (22%), Positives = 54/131 (41%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LD +RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDTVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|173L| Lysozyme (E.C.3.2.1.17) Mutant With Lys 16 Replaced By Glu, Arg
119 Replaced By Glu, Lys 135 Replaced By Glu, Lys 147
Replaced By Glu (K16e,R119e,K135e,K147e)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 29/139 (20%), Positives = 57/139 (40%), Gaps = 29/139 (20%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLEIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLEMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQVKKERQGI 113
L +S ++NQ + +
Sbjct: 131 VNLAESRWYNQTPNRAERV 149
>pdb|131L| Lysozyme (E.C.3.2.1.17) Mutant With Thr 26 Replaced By Ser, Cys 54
Replaced By Thr, Cys 97 Replaced By Ala (T26s,C54t,
C97a)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|250L| The Response Of T4 Lysozyme To Large-To-Small Substitutions Within
The Core And Its Relation To The Hydrophobic Effect
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGAGHLLTKSPSLNAAKSELDKAIGRNTNGVATKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR ++++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
>pdb|1QT6|A Chain A, E11h Mutant Of T4 Lysozyme
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 16/54 (29%), Positives = 32/54 (58%)
Query: 52 YKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAVERLQKSPYFNQ 105
Y +LDA+RR ++++ + +G G+ F ++ ++ K + A L KS ++NQ
Sbjct: 88 YDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQ 141
>pdb|1L54| Lysozyme (E.C.3.2.1.17) (Mutant With Cys 54 Replaced By Thr, Cys
97 Replaced By Ala, Met 102 Replaced By Lys)
(C54T,C97A,M102K)
Length = 164
Score = 38.5 bits (88), Expect = 2e-04
Identities = 30/131 (22%), Positives = 54/131 (40%), Gaps = 29/131 (22%)
Query: 4 EGFSPSIYTDKTGHPTIGYGYNLS-----------------------VYSYEGKRI---- 36
EG IY D G+ TIG G+ L+ + E +++
Sbjct: 11 EGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQD 70
Query: 37 --TKTYGLLTDILSYGWYKNLDAMRRMVILDLSYNLGLNGLLKFKQFIKAIEDKNYALAV 94
G+L + Y +LDA+RR +++ + +G G+ F ++ ++ K + A
Sbjct: 71 VDAAVRGILRNAKLKPVYDSLDAVRRAALINKVFQMGETGVAGFTNSLRMLQQKRWDEAA 130
Query: 95 ERLQKSPYFNQ 105
L KS ++NQ
Sbjct: 131 VNLAKSRWYNQ 141
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
Posted date: Dec 20, 2002 11:08 AM
Number of letters in database: 2,899,336
Number of sequences in database: 13,198
Lambda K H
0.319 0.140 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 741,362
Number of Sequences: 13198
Number of extensions: 31200
Number of successful extensions: 623
Number of sequences better than 10.0: 303
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 33
Number of HSP's gapped (non-prelim): 590
length of query: 116
length of database: 2,899,336
effective HSP length: 76
effective length of query: 40
effective length of database: 1,896,288
effective search space: 75851520
effective search space used: 75851520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 48 (23.1 bits)