BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15645443|ref|NP_207617.1| thioredoxin (trxA)
[Helicobacter pylori 26695]
(106 letters)
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
13,198 sequences; 2,899,336 total letters
Searching...........................done
Score E
Sequences producing significant alignments: (bits) Value
pdb|1XOB|A Chain A, Thioredoxin (Reduced Dithio Form), Nmr,... 108 9e-26
pdb|1XOB| Thioredoxin (Reduced Dithio Form), Nmr, 20 Stru... 108 9e-26
pdb|2TIR| Thioredoxin Mutant With Lys 36 Replaced By Glu ... 107 3e-25
pdb|1F6M|C Chain C, Crystal Structure Of A Complex Between ... 104 1e-24
pdb|1THO| Thioredoxin Mutant With Arg Inserted Between Gl... 103 2e-24
pdb|1FB0|A Chain A, Crystal Structure Of Thioredoxin M From... 102 5e-24
pdb|1GL8|A Chain A, Solution Structure Of Thioredoxin M Fro... 102 5e-24
pdb|1SRX| Three-Dimensional Structure Of Escherichia Coli... 101 1e-23
pdb|1TXX|A Chain A, Active-Site Variant Of E.Coli Thioredoxin 100 2e-23
pdb|1QUW|A Chain A, Solution Structure Of The Thioredoxin F... 99 7e-23
pdb|1DBY|A Chain A, Nmr Structures Of Chloroplast Thioredox... 97 3e-22
pdb|1M7T|A Chain A, Solution Structure And Dynamics Of The ... 74 3e-15
pdb|1THX| Thioredoxin-2 67 4e-13
pdb|1EP7|A Chain A, Crystal Structure Of Wt Thioredoxin H F... 64 2e-12
pdb|1EP8|A Chain A, Crystal Structure Of A Mutated Thioredo... 61 2e-11
pdb|1MEK| Human Protein Disulfide Isomerase, Nmr, 40 Stru... 60 4e-11
pdb|1ERV| Human Thioredoxin Mutant With Cys 73 Replaced B... 58 2e-10
pdb|1TRS| Thioredoxin Mutant With Cys 62 Replaced By Ala,... 57 4e-10
pdb|1ERT| Human Thioredoxin (Reduced Form) >gi|2982059|pd... 56 7e-10
pdb|3TRX| Thioredoxin (Reduced Form) >gi|231098|pdb|4TRX|... 55 1e-09
pdb|1AIU| Human Thioredoxin (D60n Mutant, Reduced Form) 54 3e-09
pdb|1CQG|A Chain A, High Resolution Solution Nmr Structure ... 53 4e-09
pdb|1F9M|A Chain A, Crystal Structure Of Thioredoxin F From... 52 7e-09
pdb|1FAA|A Chain A, Crystal Structure Of Thioredoxin F From... 52 7e-09
pdb|1ERW| Human Thioredoxin Double Mutant With Cys 32 Rep... 48 1e-07
pdb|1FO5|A Chain A, Solution Structure Of Reduced Mj0307 46 7e-07
pdb|1KNG|A Chain A, Crystal Structure Of Ccmg Reducing Oxid... 41 2e-05
pdb|1JFU|B Chain B, Crystal Structure Of The Soluble Domain... 38 2e-04
pdb|1GH2|A Chain A, Crystal Structure Of The Catalytic Doma... 36 7e-04
pdb|2TRC|P Chain P, PhosducinTRANSDUCIN BETA-Gamma Complex 33 0.004
pdb|1B9Y|C Chain C, Structural Analysis Of Phosducin And It... 33 0.004
pdb|1B9X|C Chain C, Structural Analysis Of Phosducin And It... 33 0.004
pdb|1AXE|A Chain A, Crystal Structure Of The Active-Site Mu... 31 0.023
pdb|1A71|A Chain A, Ternary Complex Of An Active Site Doubl... 31 0.023
pdb|1A0R|P Chain P, Heterotrimeric Complex Of PhosducinTRAN... 30 0.052
pdb|1E3L|A Chain A, P47h Mutant Of Mouse Class Ii Alcohol D... 29 0.068
pdb|1E3I|A Chain A, Mouse Class Ii Alcohol Dehydrogenase Co... 29 0.068
pdb|1HT0|A Chain A, Human Gamma-2 Alcohol Dehydrogense >gi|... 29 0.068
pdb|1EZK|A Chain A, Crystal Structure Of Recombinant Trypar... 27 0.34
pdb|1QLH|A Chain A, Horse Liver Alcohol Dehydrogenase Compl... 27 0.34
pdb|1HET|A Chain A, Atomic X-Ray Structure Of Liver Alcohol... 27 0.34
pdb|1EWX|A Chain A, Crystal Structure Of Native Tryparedoxi... 27 0.34
pdb|1AXG|A Chain A, Crystal Structure Of The Val203->ala Mu... 27 0.34
pdb|1QK8|A Chain A, Tryparedoxin-I From Crithidia Fasciculata 27 0.34
pdb|1JU9|A Chain A, Horse Liver Alcohol Dehydrogenase Val29... 27 0.34
pdb|1FG4|A Chain A, Structure Of Tryparedoxin Ii >gi|142783... 27 0.44
pdb|7ADH| Isonicotinimidylated Liver Alcohol Dehydrogenas... 27 0.44
pdb|1HTB|A Chain A, Crystallization Of Human Beta3 Alcohol ... 26 0.75
pdb|1DEH|A Chain A, Crystallization Of Human Beta1 Alcohol ... 26 0.75
pdb|1HDY|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Be... 26 0.75
pdb|1HDZ|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Be... 26 0.75
pdb|1EE2|B Chain B, The Structure Of Steroid-Active Alcohol... 25 0.98
pdb|1EE2|A Chain A, The Structure Of Steroid-Active Alcohol... 25 0.98
pdb|1LQT|A Chain A, A Covalent Modification Of Nadp+ Reveal... 25 1.7
pdb|1KCW| X-Ray Crystal Structure Of Human Ceruloplasmin ... 24 2.2
pdb|1M44|A Chain A, Aminoglycoside 2'-N-Acetyltransferase F... 24 2.8
pdb|1HYB|A Chain A, Crystal Structure Of An Active Site Mut... 23 3.7
pdb|1M6H|A Chain A, Human Glutathione-Dependent Formaldehyd... 23 3.7
pdb|1EJ2|A Chain A, Crystal Structure Of Methanobacterium T... 23 3.7
pdb|1AO8| Dihydrofolate Reductase Complexed With Methotre... 23 4.9
pdb|3DFR| Dihydrofolate Reductase (E.C.1.5.1.3) Complex W... 23 4.9
pdb|1BMO|A Chain A, Bm-40, FsEC DOMAIN PAIR >gi|2624794|pdb... 23 6.3
pdb|1IE5|A Chain A, Nmr Structure Of The Third Immunoglobul... 23 6.3
pdb|1NUB|A Chain A, Helix C Deletion Mutant Of Bm-40 Fs-Ec ... 23 6.3
pdb|1URO|A Chain A, Uroporphyrinogen Decarboxylase 22 8.3
pdb|1G0D|A Chain A, Crystal Structure Of Red Sea Bream Tran... 22 8.3
pdb|1HSO|A Chain A, Human Alpha Alcohol Dehydrogenase (Adh1... 22 8.3
pdb|1JPK|A Chain A, Gly156asp Mutant Of Human Urod, Human U... 22 8.3
pdb|1JPI|A Chain A, Phe232leu Mutant Of Human Urod, Human U... 22 8.3
>pdb|1XOB|A Chain A, Thioredoxin (Reduced Dithio Form), Nmr, 20 Structures
pdb|1XOA| Thioredoxin (Oxidized Disulfide Form), Nmr, 20 Structures
Length = 108
Score = 108 bits (270), Expect = 9e-26
Identities = 50/100 (50%), Positives = 70/100 (70%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WCGPCKM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|1XOB| Thioredoxin (Reduced Dithio Form), Nmr, 20 Structures
pdb|2TRX|A Chain A, Thioredoxin
pdb|2TRX|B Chain B, Thioredoxin
pdb|1T7P|B Chain B, T7 Dna Polymerase Complexed To Dna PrimerTEMPLATE,A
Nucleoside Triphosphate, And Its Processivity Factor
Thioredoxin
Length = 108
Score = 108 bits (270), Expect = 9e-26
Identities = 50/100 (50%), Positives = 70/100 (70%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WCGPCKM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|2TIR| Thioredoxin Mutant With Lys 36 Replaced By Glu (K36e)
Length = 108
Score = 107 bits (266), Expect = 3e-25
Identities = 49/100 (49%), Positives = 70/100 (70%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WCGPC+M++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCGPCEMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|1F6M|C Chain C, Crystal Structure Of A Complex Between Thioredoxin
Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
pdb|1F6M|D Chain D, Crystal Structure Of A Complex Between Thioredoxin
Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
pdb|1F6M|G Chain G, Crystal Structure Of A Complex Between Thioredoxin
Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
pdb|1F6M|H Chain H, Crystal Structure Of A Complex Between Thioredoxin
Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
Length = 108
Score = 104 bits (260), Expect = 1e-24
Identities = 49/100 (49%), Positives = 69/100 (69%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WCGP KM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCGPSKMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|1THO| Thioredoxin Mutant With Arg Inserted Between Gly 33 And Pro 34
(33r34)
Length = 109
Score = 103 bits (258), Expect = 2e-24
Identities = 50/101 (49%), Positives = 70/101 (68%), Gaps = 3/101 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCG-PCKMLSPVIDELASEYEGKAKICKVNTDEQ 61
I LT+++F++ + K G LVDFWA WCG PCKM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCGRPCKMIAPILDEIADEYQGKLTVAKLNIDQN 64
Query: 62 EELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 PGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 105
>pdb|1FB0|A Chain A, Crystal Structure Of Thioredoxin M From Spinach
Chloroplast (Reduced Form)
pdb|1FB6|A Chain A, Crystal Structure Of Thioredoxin M From Spinach
Chloroplast (Oxidized Form)
pdb|1FB6|B Chain B, Crystal Structure Of Thioredoxin M From Spinach
Chloroplast (Oxidized Form)
pdb|1FB0|B Chain B, Crystal Structure Of Thioredoxin M From Spinach
Chloroplast (Reduced Form)
Length = 105
Score = 102 bits (255), Expect = 5e-24
Identities = 44/84 (52%), Positives = 60/84 (71%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKD 81
+VDFWAPWCGPCK+++PVIDELA EY GK + K+NTDE ++ ++ IRSIPT+LF K+
Sbjct: 22 MVDFWAPWCGPCKLIAPVIDELAKEYSGKIAVYKLNTDEAPGIATQYNIRSIPTVLFFKN 81
Query: 82 GEVVHQLVGVQTKVALKEQLNKLL 105
GE ++G K L + + K L
Sbjct: 82 GERKESIIGAVPKSTLTDSIEKYL 105
>pdb|1GL8|A Chain A, Solution Structure Of Thioredoxin M From Spinach, Oxidized
Form
Length = 104
Score = 102 bits (255), Expect = 5e-24
Identities = 44/84 (52%), Positives = 60/84 (71%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKD 81
+VDFWAPWCGPCK+++PVIDELA EY GK + K+NTDE ++ ++ IRSIPT+LF K+
Sbjct: 21 MVDFWAPWCGPCKLIAPVIDELAKEYSGKIAVYKLNTDEAPGIATQYNIRSIPTVLFFKN 80
Query: 82 GEVVHQLVGVQTKVALKEQLNKLL 105
GE ++G K L + + K L
Sbjct: 81 GERKESIIGAVPKSTLTDSIEKYL 104
>pdb|1SRX| Three-Dimensional Structure Of Escherichia Coli Thioredoxin- S2 To
2.8 Angstroms Resolution
Length = 108
Score = 101 bits (252), Expect = 1e-23
Identities = 48/100 (48%), Positives = 68/100 (68%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WCGPCKM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDLVKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+ R IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYIERGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|1TXX|A Chain A, Active-Site Variant Of E.Coli Thioredoxin
Length = 108
Score = 100 bits (250), Expect = 2e-23
Identities = 48/100 (48%), Positives = 68/100 (68%), Gaps = 2/100 (2%)
Query: 5 IELTEENFESTIKK--GVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I LT+++F++ + K G LVDFWA WC CKM++P++DE+A EY+GK + K+N D+
Sbjct: 5 IHLTDDSFDTDVLKADGAILVDFWAEWCVWCKMIAPILDEIADEYQGKLTVAKLNIDQNP 64
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLN 102
+ K+GIR IPTLL K+GEV VG +K LKE L+
Sbjct: 65 GTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLD 104
>pdb|1QUW|A Chain A, Solution Structure Of The Thioredoxin From Bacillus
Acidocaldarius
Length = 105
Score = 99.0 bits (245), Expect = 7e-23
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 1/100 (1%)
Query: 7 LTEENFESTIKKGV-ALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELS 65
LT+ NF+ I+ LVDFWA WCGPC+M++PV++E A + K + K+N DE E +
Sbjct: 5 LTDANFQQAIQGDKPVLVDFWAAWCGPCRMMAPVLEEFAEAHADKVTVAKLNVDENPETT 64
Query: 66 AKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLNKLL 105
++FGI SIPTL+ K G V QL+G Q K L+ QL +L
Sbjct: 65 SQFGIMSIPTLILFKGGRPVKQLIGYQPKEQLEAQLADVL 104
>pdb|1DBY|A Chain A, Nmr Structures Of Chloroplast Thioredoxin M Ch2 From The
Green Alga Chlamydomonas Reinhardtii
Length = 107
Score = 97.1 bits (240), Expect = 3e-22
Identities = 39/84 (46%), Positives = 60/84 (71%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKD 81
LVDFWAPWCGPC++++PV+DE+A EY+ K K K+NTDE +++++GIRSIPT++ K
Sbjct: 23 LVDFWAPWCGPCRIIAPVVDEIAGEYKDKLKCVKLNTDESPNVASEYGIRSIPTIMVFKG 82
Query: 82 GEVVHQLVGVQTKVALKEQLNKLL 105
G+ ++G K + + + K L
Sbjct: 83 GKKCETIIGAVPKATIVQTVEKYL 106
>pdb|1M7T|A Chain A, Solution Structure And Dynamics Of The Human-Escherichia
Coli Thioredoxin Chimera: Insights Into Thermodynamic
Stability
Length = 107
Score = 73.6 bits (179), Expect = 3e-15
Identities = 36/83 (43%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y + +V+ D+ ++++ K+GIR IPTLL
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFL-EVDVDDAQDVAPKYGIRGIPTLLLF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLN 102
K+GEV VG +K LKE L+
Sbjct: 81 KNGEVAATKVGALSKGQLKEFLD 103
>pdb|1THX| Thioredoxin-2
Length = 115
Score = 66.6 bits (161), Expect = 4e-13
Identities = 31/92 (33%), Positives = 50/92 (53%), Gaps = 2/92 (2%)
Query: 5 IELTEENFESTIKKGV--ALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
I +T+ FES + K LV FWA WCGPC+++SP+I+ A+ Y + K+ K+ D
Sbjct: 10 ITITDAEFESEVLKAEQPVLVYFWASWCGPCQLMSPLINLAANTYSDRLKVVKLEIDPNP 69
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTK 94
K+ + +P L K +++ GV +K
Sbjct: 70 TTVKKYKVEGVPALRLVKGEQILDSTEGVISK 101
>pdb|1EP7|A Chain A, Crystal Structure Of Wt Thioredoxin H From Chlamydomonas
Reinhardtii
pdb|1EP7|B Chain B, Crystal Structure Of Wt Thioredoxin H From Chlamydomonas
Reinhardtii
pdb|1TOF| Thioredoxin H (Oxidized Form), Nmr, 23 Structures
Length = 112
Score = 64.3 bits (155), Expect = 2e-12
Identities = 29/69 (42%), Positives = 42/69 (60%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKD 81
+VDF A WCGPCKM++P+ + L+++Y GK KV+ D ++ GI ++PT KD
Sbjct: 28 VVDFTATWCGPCKMIAPLFETLSNDYAGKVIFLKVDVDAVAAVAEAAGITAMPTFHVYKD 87
Query: 82 GEVVHQLVG 90
G LVG
Sbjct: 88 GVKADDLVG 96
>pdb|1EP8|A Chain A, Crystal Structure Of A Mutated Thioredoxin, D30a, From
Chlamydomonas Reinhardtii
pdb|1EP8|B Chain B, Crystal Structure Of A Mutated Thioredoxin, D30a, From
Chlamydomonas Reinhardtii
Length = 112
Score = 61.2 bits (147), Expect = 2e-11
Identities = 28/69 (40%), Positives = 41/69 (58%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKD 81
+V F A WCGPCKM++P+ + L+++Y GK KV+ D ++ GI ++PT KD
Sbjct: 28 VVAFTATWCGPCKMIAPLFETLSNDYAGKVIFLKVDVDAVAAVAEAAGITAMPTFHVYKD 87
Query: 82 GEVVHQLVG 90
G LVG
Sbjct: 88 GVKADDLVG 96
>pdb|1MEK| Human Protein Disulfide Isomerase, Nmr, 40 Structures
Length = 120
Score = 60.1 bits (144), Expect = 4e-11
Identities = 28/85 (32%), Positives = 51/85 (59%), Gaps = 4/85 (4%)
Query: 3 HYIELTEENF-ESTIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKA---KICKVNT 58
H + L + NF E+ LV+F+APWCG CK L+P + A + + + ++ KV+
Sbjct: 8 HVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA 67
Query: 59 DEQEELSAKFGIRSIPTLLFTKDGE 83
E+ +L+ ++G+R PT+ F ++G+
Sbjct: 68 TEESDLAQQYGVRGYPTIKFFRNGD 92
>pdb|1ERV| Human Thioredoxin Mutant With Cys 73 Replaced By Ser (Reduced
Form)
Length = 105
Score = 57.8 bits (138), Expect = 2e-10
Identities = 28/86 (32%), Positives = 51/86 (58%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y +V+ D+ ++++++ ++S+PT F
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKSMPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1TRS| Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Oxidized)
(Nmr, Minimized Average Structure)
pdb|1TRU| Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Oxidized)
(Nmr, 40 Structures)
pdb|1TRV| Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Reduced)
(Nmr, 40 Structures)
pdb|1TRW| Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Reduced)
(Nmr, Minimized Average Structure)
Length = 105
Score = 56.6 bits (135), Expect = 4e-10
Identities = 27/86 (31%), Positives = 50/86 (57%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y +V+ D+ ++++++ +++ PT F
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDAQDVASEAEVKATPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1ERT| Human Thioredoxin (Reduced Form)
pdb|1AUC| Human Thioredoxin (Oxidized With Diamide)
pdb|1ERU| Human Thioredoxin (Oxidized Form)
Length = 105
Score = 55.8 bits (133), Expect = 7e-10
Identities = 27/86 (31%), Positives = 50/86 (57%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y +V+ D+ ++++++ ++ +PT F
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKCMPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|3TRX| Thioredoxin (Reduced Form)
pdb|4TRX| Thioredoxin (Reduced Form)
Length = 105
Score = 55.1 bits (131), Expect = 1e-09
Identities = 27/86 (31%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y +V+ D+ ++++++ ++ PT F
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKCTPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1AIU| Human Thioredoxin (D60n Mutant, Reduced Form)
Length = 105
Score = 53.9 bits (128), Expect = 3e-09
Identities = 26/86 (30%), Positives = 50/86 (57%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGPCKM+ P L+ +Y +V+ ++ ++++++ ++ +PT F
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLSEKY-SNVIFLEVDVNDCQDVASECEVKCMPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1CQG|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
Intermediate Between Human Thioredoxin (C35a, C62a,
C69a, C73a) Mutant And A 13 Residue Peptide Comprising
Its Target Site In Human Ref-1 (Residues 59 - 71 Of The
P50 Subunit Of Nfkb), Nmr, 31 Structures
pdb|1CQH|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
Intermediate Between Human Thioredoxin (C35a, C62a,
C69a, C73a) Mutant And A 13 Residue Peptide Comprising
Its Target Site In Human Ref-1 (Residues 59 - 71 Of The
P50 Subunit Of Nfkb), Nmr, Minimized Average Structure
pdb|1MDI|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
Intermediate Between Mutant Human Thioredoxin And A 13
Residue Peptide Comprising Its Target Site In Human Nfkb
pdb|1MDJ|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
Intermediate Between Human Thioredoxin (C35a, C62a,
C69a, C73a) Mutant And A 13 Residue Peptide Comprising
Its Target Site In Human Nfkb (Residues 56-68 Of The P50
Subunit Of Nfkb)
pdb|1MDK|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
Intermediate Between Human Thioredoxin (C35a, C62a,
C69a, C73a) Mutant And A 13 Residue Peptide Comprising
Its Target Site In Human Nfkb (Residues 56-68 Of The P50
Subunit Of Nfkb)
Length = 105
Score = 53.1 bits (126), Expect = 4e-09
Identities = 26/86 (30%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A WCGP KM+ P L+ +Y +V+ D+ ++++++ +++ PT F
Sbjct: 22 LVVVDFSATWCGPAKMIKPFFHSLSEKY-SNVIFLEVDVDDAQDVASEAEVKATPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1F9M|A Chain A, Crystal Structure Of Thioredoxin F From Spinach
Chloroplast (Short Form)
pdb|1F9M|B Chain B, Crystal Structure Of Thioredoxin F From Spinach
Chloroplast (Short Form)
Length = 112
Score = 52.4 bits (124), Expect = 7e-09
Identities = 26/90 (28%), Positives = 46/90 (50%), Gaps = 3/90 (3%)
Query: 6 ELTEENFESTIKKG---VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
E+ ++ F +K ++D + WCGPCK ++P ++LA EY + E +
Sbjct: 10 EVNKDTFWPIVKAAGDKPVVLDMFTQWCGPCKAMAPKYEKLAEEYLDVIFLKLDCNQENK 69
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQ 92
L+ + GIR +PT K+ VV ++ G +
Sbjct: 70 TLAKELGIRVVPTFKILKENSVVGEVTGAK 99
>pdb|1FAA|A Chain A, Crystal Structure Of Thioredoxin F From Spinach
Chloroplast (Long Form)
Length = 124
Score = 52.4 bits (124), Expect = 7e-09
Identities = 26/90 (28%), Positives = 46/90 (50%), Gaps = 3/90 (3%)
Query: 6 ELTEENFESTIKKG---VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQE 62
E+ ++ F +K ++D + WCGPCK ++P ++LA EY + E +
Sbjct: 22 EVNKDTFWPIVKAAGDKPVVLDMFTQWCGPCKAMAPKYEKLAEEYLDVIFLKLDCNQENK 81
Query: 63 ELSAKFGIRSIPTLLFTKDGEVVHQLVGVQ 92
L+ + GIR +PT K+ VV ++ G +
Sbjct: 82 TLAKELGIRVVPTFKILKENSVVGEVTGAK 111
>pdb|1ERW| Human Thioredoxin Double Mutant With Cys 32 Replaced By Ser And
Cys 35 Replaced By Ser
Length = 105
Score = 48.1 bits (113), Expect = 1e-07
Identities = 25/86 (29%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+ +VDF A W GP KM+ P L+ +Y +V+ D+ ++++++ ++ +PT F
Sbjct: 22 LVVVDFSATWSGPSKMIKPFFHSLSEKY-SNVIFLEVDVDDCQDVASECEVKCMPTFQFF 80
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
K G+ V + G K L+ +N+L+
Sbjct: 81 KKGQKVGEFSGA-NKEKLEATINELV 105
>pdb|1FO5|A Chain A, Solution Structure Of Reduced Mj0307
Length = 85
Score = 45.8 bits (107), Expect = 7e-07
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 25 FWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKDGEV 84
F +P C C V++E+A+E ++ +N E + + ++GI ++PT++ D E
Sbjct: 9 FTSPMCPHCPAAKRVVEEVANEMPDAVEVEYINVMENPQKAMEYGIMAVPTIVINGDVE- 67
Query: 85 VHQLVGVQTKVALKEQLNKLL 105
+G TK AL E + K L
Sbjct: 68 ---FIGAPTKEALVEAIKKRL 85
>pdb|1KNG|A Chain A, Crystal Structure Of Ccmg Reducing Oxidoreductase At 1.14
A
Length = 156
Score = 41.2 bits (95), Expect = 2e-05
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 22/110 (20%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASE---------YEGKA------------K 52
+ K V+LV+ WA WC PC +P++ EL + Y+ A
Sbjct: 38 AAFKGKVSLVNVWASWCVPCHDEAPLLTELGKDKRFQLVGINYKDAADNARRFLGRYGNP 97
Query: 53 ICKVNTDEQEELSAKFGIRSIP-TLLFTKDGEVVHQLVGVQTKVALKEQL 101
+V D S ++G+ +P T + ++G +V++LVG T L+ L
Sbjct: 98 FGRVGVDANGRASIEWGVYGVPETFVVGREGTIVYKLVGPITPDNLRSVL 147
>pdb|1JFU|B Chain B, Crystal Structure Of The Soluble Domain Of Tlpa From
Bradyrhizobium Japonicum
pdb|1JFU|A Chain A, Crystal Structure Of The Soluble Domain Of Tlpa From
Bradyrhizobium Japonicum
Length = 186
Score = 37.7 bits (86), Expect = 2e-04
Identities = 15/42 (35%), Positives = 24/42 (56%), Gaps = 1/42 (2%)
Query: 22 LVDFWAPWCGPCKMLSPVIDELASEYEG-KAKICKVNTDEQE 62
LV+ WA WC PC+ P +DEL + G ++ +N D ++
Sbjct: 64 LVNLWATWCVPCRKEMPALDELQGKLSGPNFEVVAINIDTRD 105
>pdb|1GH2|A Chain A, Crystal Structure Of The Catalytic Domain Of A New Human
Thioredoxin-Like Protein
Length = 107
Score = 35.8 bits (81), Expect = 7e-04
Identities = 22/86 (25%), Positives = 44/86 (50%), Gaps = 2/86 (2%)
Query: 20 VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
+A+V F CGPC ++P ++++Y +A +V+ + + +A I + PT F
Sbjct: 23 LAVVKFTMRGCGPCLRIAPAFSSMSNKYP-QAVFLEVDVHQCQGTAATNNISATPTFQFF 81
Query: 80 KDGEVVHQLVGVQTKVALKEQLNKLL 105
++ + Q G V L+E++ + L
Sbjct: 82 RNKVRIDQYQGADA-VGLEEKIKQHL 106
>pdb|2TRC|P Chain P, PhosducinTRANSDUCIN BETA-Gamma Complex
Length = 217
Score = 33.5 bits (75), Expect = 0.004
Identities = 26/93 (27%), Positives = 41/93 (43%), Gaps = 6/93 (6%)
Query: 8 TEENFESTIKKG----VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEE 63
T E F TI+K +V+ + C L+ ++ LA+EY K CK+
Sbjct: 106 TGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLECLAAEYPX-VKFCKIRASNTGA 164
Query: 64 LSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVA 96
+F +PTLL K GE++ + V + A
Sbjct: 165 -GDRFSSDVLPTLLVYKGGELISNFISVAEQFA 196
>pdb|1B9Y|C Chain C, Structural Analysis Of Phosducin And Its Phosphorylation-
Regulated Interaction With Transducin Beta-Gamma
Length = 246
Score = 33.5 bits (75), Expect = 0.004
Identities = 26/93 (27%), Positives = 41/93 (43%), Gaps = 6/93 (6%)
Query: 8 TEENFESTIKKG----VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEE 63
T E F TI+K +V+ + C L+ ++ LA+EY K CK+
Sbjct: 119 TGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLECLAAEYP-MVKFCKIRASNTGA 177
Query: 64 LSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVA 96
+F +PTLL K GE++ + V + A
Sbjct: 178 -GDRFSSDVLPTLLVYKGGELISNFISVAEQFA 209
>pdb|1B9X|C Chain C, Structural Analysis Of Phosducin And Its Phosphorylation-
Regulated Interaction With Transducin
Length = 246
Score = 33.5 bits (75), Expect = 0.004
Identities = 26/93 (27%), Positives = 41/93 (43%), Gaps = 6/93 (6%)
Query: 8 TEENFESTIKKG----VALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEE 63
T E F TI+K +V+ + C L+ ++ LA+EY K CK+
Sbjct: 119 TGEQFLETIEKEQKVTTIVVNIYEDGVRGCDALNSSLECLAAEYP-MVKFCKIRASNTGA 177
Query: 64 LSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVA 96
+F +PTLL K GE++ + V + A
Sbjct: 178 -GDRFSSDVLPTLLVYKGGELISNFISVAEQFA 209
>pdb|1AXE|A Chain A, Crystal Structure Of The Active-Site Mutant Phe93->trp Of
Horse Liver Alcohol Dehydrogenase In Complex With Nad
And Inhibitor Trifluoroethanol
pdb|1AXE|B Chain B, Crystal Structure Of The Active-Site Mutant Phe93->trp Of
Horse Liver Alcohol Dehydrogenase In Complex With Nad
And Inhibitor Trifluoroethanol
Length = 374
Score = 30.8 bits (68), Expect = 0.023
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ W P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLWTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1A71|A Chain A, Ternary Complex Of An Active Site Double Mutant Of Horse
Liver Alcohol Dehydrogenase, Phe93>trp, Val203>ala With
Nad And Trifluoroethanol
pdb|1A71|B Chain B, Ternary Complex Of An Active Site Double Mutant Of Horse
Liver Alcohol Dehydrogenase, Phe93>trp, Val203>ala With
Nad And Trifluoroethanol
pdb|1A72| An Active-Site Double Mutant (Phe93->trp, Val203->ala) Of Horse
Liver Alcohol Dehydrogenase In Complex With The
Isosteric Nad Analog Cpad
Length = 374
Score = 30.8 bits (68), Expect = 0.023
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ W P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLWTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1A0R|P Chain P, Heterotrimeric Complex Of PhosducinTRANSDUCIN BETA-Gamma
Length = 245
Score = 29.6 bits (65), Expect = 0.052
Identities = 23/87 (26%), Positives = 36/87 (40%), Gaps = 2/87 (2%)
Query: 10 ENFESTIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFG 69
E E K +V + C L+ + LA+EY K CK+ +F
Sbjct: 125 ETIEKEQKITTIVVHIYEDGIKGCDALNSSLICLAAEYP-MVKFCKIKASNTGA-GDRFS 182
Query: 70 IRSIPTLLFTKDGEVVHQLVGVQTKVA 96
+PTLL K GE++ + V ++A
Sbjct: 183 SDVLPTLLVYKGGELLSNFISVTEQLA 209
>pdb|1E3L|A Chain A, P47h Mutant Of Mouse Class Ii Alcohol Dehydrogenase
Complex With Nadh
pdb|1E3L|B Chain B, P47h Mutant Of Mouse Class Ii Alcohol Dehydrogenase
Complex With Nadh
Length = 376
Score = 29.3 bits (64), Expect = 0.068
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 14 STIKKGVALVDFWAPWCGPCKM-LSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRS 72
+ K G ++ F+AP C CK+ LSP+ + GK + K T +QE + +
Sbjct: 81 TNFKPGDKVIPFFAPQCKRCKLCLSPL-----TNLCGKLRNFKYPTIDQELMEDR----- 130
Query: 73 IPTLLFTKDGEVVHQLVGVQT 93
T FT G ++ +GV +
Sbjct: 131 --TSRFTCKGRSIYHFMGVSS 149
>pdb|1E3I|A Chain A, Mouse Class Ii Alcohol Dehydrogenase Complex With Nadh And
Inhibitor
pdb|1E3E|A Chain A, Mouse Class Ii Alcohol Dehydrogenase Complex With Nadh
pdb|1E3I|B Chain B, Mouse Class Ii Alcohol Dehydrogenase Complex With Nadh And
Inhibitor
pdb|1E3E|B Chain B, Mouse Class Ii Alcohol Dehydrogenase Complex With Nadh
Length = 376
Score = 29.3 bits (64), Expect = 0.068
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 14 STIKKGVALVDFWAPWCGPCKM-LSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRS 72
+ K G ++ F+AP C CK+ LSP+ + GK + K T +QE + +
Sbjct: 81 TNFKPGDKVIPFFAPQCKRCKLCLSPL-----TNLCGKLRNFKYPTIDQELMEDR----- 130
Query: 73 IPTLLFTKDGEVVHQLVGVQT 93
T FT G ++ +GV +
Sbjct: 131 --TSRFTCKGRSIYHFMGVSS 149
>pdb|1HT0|A Chain A, Human Gamma-2 Alcohol Dehydrogense
pdb|1HT0|B Chain B, Human Gamma-2 Alcohol Dehydrogense
Length = 374
Score = 29.3 bits (64), Expect = 0.068
Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ + P CG C++ ++ C N +L G
Sbjct: 81 TTVKPGDKVIPLFTPQCGKCRICK----------NPESNYCLKN-----DLGNPRGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H VGV T
Sbjct: 126 GTRRFTCSGKPIHHFVGVST 145
>pdb|1EZK|A Chain A, Crystal Structure Of Recombinant Tryparedoxin I
Length = 153
Score = 26.9 bits (58), Expect = 0.34
Identities = 21/79 (26%), Positives = 32/79 (39%), Gaps = 26/79 (32%)
Query: 25 FWAPWCGPCKMLSPVIDELASEY-EGK-AKICKVNTDEQEE------------------- 63
F A WC PC+ +P + E ++ E K ++ DE+E+
Sbjct: 34 FSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEEDGFAGYFAKMPWLAVPFAQS 93
Query: 64 -----LSAKFGIRSIPTLL 77
LS F + SIPTL+
Sbjct: 94 EAVQKLSKHFNVESIPTLI 112
>pdb|1QLH|A Chain A, Horse Liver Alcohol Dehydrogenase Complexed To Nad Double
Mutant Of Gly 293 Ala And Pro 295 Thr
pdb|1QLJ|A Chain A, Horse Liver Alcohol Dehydrogenase Apo Enzyme Double Mutant
Of Gly 293 Ala And Pro 295 Thr
Length = 374
Score = 26.9 bits (58), Expect = 0.34
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLFTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1HET|A Chain A, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing A Hydroxide Adduct To Nadh
pdb|1HET|B Chain B, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing A Hydroxide Adduct To Nadh
pdb|1HEU|A Chain A, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing Cadmium And A Hydroxide Adduct To Nadh
pdb|1HEU|B Chain B, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing Cadmium And A Hydroxide Adduct To Nadh
pdb|3BTO|A Chain A, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3s)3-Butylthiolane 1-Oxide
pdb|3BTO|B Chain B, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3s)3-Butylthiolane 1-Oxide
pdb|3BTO|C Chain C, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3s)3-Butylthiolane 1-Oxide
pdb|3BTO|D Chain D, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3s)3-Butylthiolane 1-Oxide
pdb|2OHX|A Chain A, Alcohol Dehydrogenase (Holo Form) (E.C.1.1.1.1) Complex
With Nadh And Dmso
pdb|2OHX|B Chain B, Alcohol Dehydrogenase (Holo Form) (E.C.1.1.1.1) Complex
With Nadh And Dmso
pdb|1HF3|A Chain A, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing Cadmium And A Hydroxide Adduct To Nadh
pdb|1HF3|B Chain B, Atomic X-Ray Structure Of Liver Alcohol Dehydrogenase
Containing Cadmium And A Hydroxide Adduct To Nadh
pdb|1BTO|A Chain A, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3r)3-Butylthiolane 1-Oxide
pdb|1BTO|B Chain B, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3r)3-Butylthiolane 1-Oxide
pdb|1BTO|C Chain C, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3r)3-Butylthiolane 1-Oxide
pdb|1BTO|D Chain D, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
(1s,3r)3-Butylthiolane 1-Oxide
pdb|1HLD|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Ee Isozyme) Complexed
With Nicotinamide Adenine Dinucleotide (Nad),
2,3,4,5,6-Penta-Fluorobenzyl Alcohol, P-Bromobenzyl
Alcohol And Zinc
pdb|1HLD|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Ee Isozyme) Complexed
With Nicotinamide Adenine Dinucleotide (Nad),
2,3,4,5,6-Penta-Fluorobenzyl Alcohol, P-Bromobenzyl
Alcohol And Zinc
pdb|2OXI|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Holo, Liver)
Complexed With Nadh And Dmso
pdb|2OXI|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Holo, Liver)
Complexed With Nadh And Dmso
pdb|1ADB|A Chain A, Alcohol Dehydrogenase (Adh) (E.C.1.1.1.1) Complexed With
5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide
(Cnad)
pdb|1ADB|B Chain B, Alcohol Dehydrogenase (Adh) (E.C.1.1.1.1) Complexed With
5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide
(Cnad)
pdb|8ADH| Apo-Liver Alcohol Dehydrogenase (E.C.1.1.99.8)
pdb|1LDE|A Chain A, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
N-Formyl Piperdine
pdb|1LDE|B Chain B, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
N-Formyl Piperdine
pdb|1LDE|C Chain C, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
N-Formyl Piperdine
pdb|1LDE|D Chain D, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
N-Formyl Piperdine
pdb|1LDY|A Chain A, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
Cyclohexyl Formamide (Cxf)
pdb|1LDY|B Chain B, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
Cyclohexyl Formamide (Cxf)
pdb|1LDY|C Chain C, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
Cyclohexyl Formamide (Cxf)
pdb|1LDY|D Chain D, Horse Liver Alcohol Dehydrogenase Complexed To Nadh And
Cyclohexyl Formamide (Cxf)
pdb|1ADC|A Chain A, Alcohol Dehydrogenase (Adh) (E.C.1.1.1.1) Complexed With
5-Beta-D-Ribofuranosylpicolinamide Adenine Dinucleotide
(Cpad)
pdb|1ADC|B Chain B, Alcohol Dehydrogenase (Adh) (E.C.1.1.1.1) Complexed With
5-Beta-D-Ribofuranosylpicolinamide Adenine Dinucleotide
(Cpad)
pdb|1ADG| Alcohol Dehydrogenase (E.C.1.1.1.1) Complexed With Inhibitor:
Beta-Methylene Selenazole-4-Carboxamide Adenine
Dinucleotide (Beta-Sad)
pdb|6ADH|A Chain A, Holo-Liver Alcohol Dehydrogenase (E.C.1.1.1.1) Complex
With Nad And Dmso
pdb|6ADH|B Chain B, Holo-Liver Alcohol Dehydrogenase (E.C.1.1.1.1) Complex
With Nad And Dmso
pdb|5ADH| Apo-Liver Alcohol Dehydrogenase (E.C.1.1.1.1) Complex With
Adp-Ribose
pdb|1ADF| Alcohol Dehydrogenase (E.C.1.1.1.1) Complexed With Inhibitor:
Beta-Methylene Thiazole-4-Carboxamide Adenine
Dinucleotide (Beta-Tad)
Length = 374
Score = 26.9 bits (58), Expect = 0.34
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLFTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1EWX|A Chain A, Crystal Structure Of Native Tryparedoxin I From Crithidia
Fasciculata
Length = 146
Score = 26.9 bits (58), Expect = 0.34
Identities = 21/79 (26%), Positives = 32/79 (39%), Gaps = 26/79 (32%)
Query: 25 FWAPWCGPCKMLSPVIDELASEY-EGK-AKICKVNTDEQEE------------------- 63
F A WC PC+ +P + E ++ E K ++ DE+E+
Sbjct: 35 FSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEEDGFAGYFAKMPWLAVPFAQS 94
Query: 64 -----LSAKFGIRSIPTLL 77
LS F + SIPTL+
Sbjct: 95 EAVQKLSKHFNVESIPTLI 113
>pdb|1AXG|A Chain A, Crystal Structure Of The Val203->ala Mutant Of Liver
Alcohol Dehydrogenase Complexed With Cofactor Nad And
Inhibitor Trifluoroethanol Solved To 2.5 Angstrom
Resolution
pdb|1AXG|B Chain B, Crystal Structure Of The Val203->ala Mutant Of Liver
Alcohol Dehydrogenase Complexed With Cofactor Nad And
Inhibitor Trifluoroethanol Solved To 2.5 Angstrom
Resolution
pdb|1AXG|C Chain C, Crystal Structure Of The Val203->ala Mutant Of Liver
Alcohol Dehydrogenase Complexed With Cofactor Nad And
Inhibitor Trifluoroethanol Solved To 2.5 Angstrom
Resolution
pdb|1AXG|D Chain D, Crystal Structure Of The Val203->ala Mutant Of Liver
Alcohol Dehydrogenase Complexed With Cofactor Nad And
Inhibitor Trifluoroethanol Solved To 2.5 Angstrom
Resolution
Length = 374
Score = 26.9 bits (58), Expect = 0.34
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLFTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1QK8|A Chain A, Tryparedoxin-I From Crithidia Fasciculata
Length = 146
Score = 26.9 bits (58), Expect = 0.34
Identities = 21/79 (26%), Positives = 32/79 (39%), Gaps = 26/79 (32%)
Query: 25 FWAPWCGPCKMLSPVIDELASEY-EGK-AKICKVNTDEQEE------------------- 63
F A WC PC+ +P + E ++ E K ++ DE+E+
Sbjct: 35 FSASWCPPCRGFTPQLIEFYDKFHESKNFEVVFCTWDEEEDGFAGYFAKMPWLAVPFAQS 94
Query: 64 -----LSAKFGIRSIPTLL 77
LS F + SIPTL+
Sbjct: 95 EAVQKLSKHFNVESIPTLI 113
>pdb|1JU9|A Chain A, Horse Liver Alcohol Dehydrogenase Val292ser Mutant
pdb|1JU9|B Chain B, Horse Liver Alcohol Dehydrogenase Val292ser Mutant
Length = 374
Score = 26.9 bits (58), Expect = 0.34
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDKVIPLFTPQCGKCRVCK----------HPEGNFCLKN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTSRFTCRGKPIHHFLGTST 145
>pdb|1FG4|A Chain A, Structure Of Tryparedoxin Ii
pdb|1FG4|B Chain B, Structure Of Tryparedoxin Ii
Length = 149
Score = 26.6 bits (57), Expect = 0.44
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 26/79 (32%)
Query: 25 FWAPWCGPCKMLSP-VIDELASEYEGK-AKICKVNTDEQEE------------------- 63
F A WC PC+ +P +ID + E K ++ ++ DE E
Sbjct: 35 FSASWCPPCRAFTPQLIDFYKAHAEKKNFEVMLISWDESAEDFKDYYAKMPWLALPFEDR 94
Query: 64 -----LSAKFGIRSIPTLL 77
L+ F ++SIPTL+
Sbjct: 95 KGMEFLTTGFDVKSIPTLV 113
>pdb|7ADH| Isonicotinimidylated Liver Alcohol Dehydrogenase (E.C.1.1.1.1)
Length = 374
Score = 26.6 bits (57), Expect = 0.44
Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C++ + C N +LS G
Sbjct: 81 TTVRPGDXVIPLFTPQCGXCRVCK----------HPEGNFCLXN-----DLSMPRGTMQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G +H +G T
Sbjct: 126 GTSRFTCRGXPIHHFLGTST 145
>pdb|1HTB|A Chain A, Crystallization Of Human Beta3 Alcohol Dehydrogenase (10
MgML) IN 100 MM SODIUM PHOSPHATE (PH 7.5), 7.5 MM Nad+
And 1 Mm 4-Iodopyrazole At 25 C
pdb|1HTB|B Chain B, Crystallization Of Human Beta3 Alcohol Dehydrogenase (10
MgML) IN 100 MM SODIUM PHOSPHATE (PH 7.5), 7.5 MM Nad+
And 1 Mm 4-Iodopyrazole At 25 C
Length = 374
Score = 25.8 bits (55), Expect = 0.75
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ + P CG C++ ++ C N +L G
Sbjct: 81 TTVKPGDKVIPLFTPQCGKCRVCK----------NPESNYCLKN-----DLGNPRGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTRRFTCRGKPIHHFLGTST 145
>pdb|1DEH|A Chain A, Crystallization Of Human Beta1 Alcohol Dehydrogenase (15
MgML) IN 50 MM SODIUM PHOSPHATE (PH 7.5), 2.0 MM NAD+
And 1 Mm 4-Iodopyrazole At 25 Oc, 13% (WV) PEG 8000
pdb|1DEH|B Chain B, Crystallization Of Human Beta1 Alcohol Dehydrogenase (15
MgML) IN 50 MM SODIUM PHOSPHATE (PH 7.5), 2.0 MM NAD+
And 1 Mm 4-Iodopyrazole At 25 Oc, 13% (WV) PEG 8000
pdb|1HSZ|A Chain A, Human Beta-1 Alcohol Dehydrogenase (Adh1b1)
pdb|1HSZ|B Chain B, Human Beta-1 Alcohol Dehydrogenase (Adh1b1)
pdb|1HDX|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme,
Human) Complexed With Nad(H) And Cyclohexanol
pdb|1HDX|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme,
Human) Complexed With Nad(H) And Cyclohexanol
pdb|3HUD|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme)
pdb|3HUD|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme)
Length = 374
Score = 25.8 bits (55), Expect = 0.75
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ + P CG C++ ++ C N +L G
Sbjct: 81 TTVKPGDKVIPLFTPQCGKCRVCK----------NPESNYCLKN-----DLGNPRGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTRRFTCRGKPIHHFLGTST 145
>pdb|1HDY|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-2 Isoenzyme,
Human) Complexed With Nad+ And 4-Iodopyrazole
pdb|1HDY|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-2 Isoenzyme,
Human) Complexed With Nad+ And 4-Iodopyrazole
Length = 374
Score = 25.8 bits (55), Expect = 0.75
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ + P CG C++ ++ C N +L G
Sbjct: 81 TTVKPGDKVIPLFTPQCGKCRVCK----------NPESNYCLKN-----DLGNPRGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTRRFTCRGKPIHHFLGTST 145
>pdb|1HDZ|A Chain A, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme,
Human) Mutant With Arg 47 Replaced By Gly (R47g)
Complexed With Nad+
pdb|1HDZ|B Chain B, Alcohol Dehydrogenase (E.C.1.1.1.1) (Beta-1 Isoenzyme,
Human) Mutant With Arg 47 Replaced By Gly (R47g)
Complexed With Nad+
Length = 374
Score = 25.8 bits (55), Expect = 0.75
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ + P CG C++ ++ C N +L G
Sbjct: 81 TTVKPGDKVIPLFTPQCGKCRVCK----------NPESNYCLKN-----DLGNPRGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 126 GTRRFTCRGKPIHHFLGTST 145
>pdb|1EE2|B Chain B, The Structure Of Steroid-Active Alcohol Dehydrogenase At
1.54 A Resolution
Length = 373
Score = 25.4 bits (54), Expect = 0.98
Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 16/80 (20%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C + + +C N LS G
Sbjct: 81 TTVRPGDKVIPLFIPQCGKCSVCK----------HPEGNLCLKN------LSMPRGTMQD 124
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 125 GTSRFTCRGKPIHHFLGTST 144
>pdb|1EE2|A Chain A, The Structure Of Steroid-Active Alcohol Dehydrogenase At
1.54 A Resolution
Length = 373
Score = 25.4 bits (54), Expect = 0.98
Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 16/80 (20%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T++ G ++ + P CG C + + +C N LS G
Sbjct: 81 TTVRPGDKVIPLFIPQCGKCSVCK----------HPEGNLCLKN------LSMPRGTMQD 124
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT G+ +H +G T
Sbjct: 125 GTSRFTCRGKPIHHFLGTST 144
>pdb|1LQT|A Chain A, A Covalent Modification Of Nadp+ Revealed By The Atomic
Resolution Structure Of Fpra, A Mycobacterium
Tuberculosis Oxidoreductase
pdb|1LQT|B Chain B, A Covalent Modification Of Nadp+ Revealed By The Atomic
Resolution Structure Of Fpra, A Mycobacterium
Tuberculosis Oxidoreductase
pdb|1LQU|A Chain A, Mycobacterium Tuberculosis Fpra In Complex With Nadph
pdb|1LQU|B Chain B, Mycobacterium Tuberculosis Fpra In Complex With Nadph
Length = 456
Score = 24.6 bits (52), Expect = 1.7
Identities = 12/33 (36%), Positives = 21/33 (63%), Gaps = 2/33 (6%)
Query: 41 DELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+EL S+ G ++ +T E+EEL A+ +RS+
Sbjct: 292 NELVSD--GSGRVAAKDTGEREELPAQLVVRSV 322
>pdb|1KCW| X-Ray Crystal Structure Of Human Ceruloplasmin At 3.0 Angstroms
Length = 1046
Score = 24.3 bits (51), Expect = 2.2
Identities = 11/29 (37%), Positives = 17/29 (57%), Gaps = 5/29 (17%)
Query: 4 YIELTEENFESTIKKGVALVDFWAPWCGP 32
Y++ T+E F +TI+K V W + GP
Sbjct: 53 YLQYTDETFRTTIEKPV-----WLGFLGP 76
>pdb|1M44|A Chain A, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Apo Structure
pdb|1M44|B Chain B, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Apo Structure
pdb|1M4D|A Chain A, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Tobramycin
pdb|1M4D|B Chain B, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Tobramycin
pdb|1M4G|A Chain A, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Ribostamycin
pdb|1M4G|B Chain B, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Ribostamycin
pdb|1M4I|A Chain A, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Kanamycin A
pdb|1M4I|B Chain B, Aminoglycoside 2'-N-Acetyltransferase From Mycobacterium
Tuberculosis-Complex With Coenzyme A And Kanamycin A
Length = 181
Score = 23.9 bits (50), Expect = 2.8
Identities = 7/13 (53%), Positives = 9/13 (68%)
Query: 26 WAPWCGPCKMLSP 38
W PW GP +L+P
Sbjct: 131 WLPWHGPTSVLAP 143
>pdb|1HYB|A Chain A, Crystal Structure Of An Active Site Mutant Of
Methanobacterium Thermoautotrophicum Nicotinamide
Mononucleotide Adenylyltransferase
Length = 181
Score = 23.5 bits (49), Expect = 3.7
Identities = 12/40 (30%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 27 APWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSA 66
A W G KML+P D + Y G + ++ +++ E++A
Sbjct: 85 ALWVGHIKMLTPPFDRV---YSGNPLVQRLFSEDGYEVTA 121
>pdb|1M6H|A Chain A, Human Glutathione-Dependent Formaldehyde Dehydrogenase
pdb|1M6H|B Chain B, Human Glutathione-Dependent Formaldehyde Dehydrogenase
pdb|1M6W|A Chain A, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase And 12-Hydroxydodecanoic Acid
pdb|1M6W|B Chain B, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase And 12-Hydroxydodecanoic Acid
pdb|1MA0|A Chain A, Ternary Complex Of Human Glutathione-Dependent
Formaldehyde Dehydrogenase With Nad+ And Dodecanoic Acid
pdb|1MA0|B Chain B, Ternary Complex Of Human Glutathione-Dependent
Formaldehyde Dehydrogenase With Nad+ And Dodecanoic Acid
pdb|1MP0|A Chain A, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase With Nad(H)
pdb|1MP0|B Chain B, Binary Complex Of Human Glutathione-Dependent Formaldehyde
Dehydrogenase With Nad(H)
pdb|1TEH|A Chain A, Structure Of Human Liver Chichi Alcohol Dehydrogenase (A
Glutathione-Dependent Formaldehyde Dehydrogenase)
pdb|1TEH|B Chain B, Structure Of Human Liver Chichi Alcohol Dehydrogenase (A
Glutathione-Dependent Formaldehyde Dehydrogenase)
Length = 373
Score = 23.5 bits (49), Expect = 3.7
Identities = 18/79 (22%), Positives = 31/79 (38%), Gaps = 17/79 (21%)
Query: 16 IKKGVALVDFWAPWCGPCKM-LSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIP 74
+K G ++ + P CG CK L+P K N ++ ++ G+
Sbjct: 82 LKAGDTVIPLYIPQCGECKFCLNP----------------KTNLCQKIRVTQGKGLMPDG 125
Query: 75 TLLFTKDGEVVHQLVGVQT 93
T FT G+ + +G T
Sbjct: 126 TSRFTCKGKTILHYMGTST 144
>pdb|1EJ2|A Chain A, Crystal Structure Of Methanobacterium Thermoautotrophicum
Nicotinamide Mononucleotide Adenylyltransferase With
Bound Nad+
Length = 181
Score = 23.5 bits (49), Expect = 3.7
Identities = 12/40 (30%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 27 APWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSA 66
A W G KML+P D + Y G + ++ +++ E++A
Sbjct: 85 ALWVGHIKMLTPPFDRV---YSGNPLVQRLFSEDGYEVTA 121
>pdb|1AO8| Dihydrofolate Reductase Complexed With Methotrexate, Nmr, 21
Structures
pdb|1BZF| Nmr Solution Structure And Dynamics Of The Complex Of
Lactobacillus Casei Dihydrofolate Reductase With The New
Lipophilic Antifolate Drug Trimetrexate, 22 Structures
pdb|1DIS| Dihydrofolate Reductase (E.C.1.5.1.3) Complex With
Brodimoprim-4,6-Dicarboxylate
pdb|1DIU| Dihydrofolate Reductase (E.C.1.5.1.3) Complex With
Brodimoprim-4,6-Dicarboxylate
Length = 162
Score = 23.1 bits (48), Expect = 4.9
Identities = 11/41 (26%), Positives = 22/41 (52%)
Query: 39 VIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
++ LA +EG K+ +N D+ ++S++ + P L T
Sbjct: 114 LVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHT 154
>pdb|3DFR| Dihydrofolate Reductase (E.C.1.5.1.3) Complex With Nadph And
Methotrexate
Length = 162
Score = 23.1 bits (48), Expect = 4.9
Identities = 11/41 (26%), Positives = 22/41 (52%)
Query: 39 VIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFT 79
++ LA +EG K+ +N D+ ++S++ + P L T
Sbjct: 114 LVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHT 154
>pdb|1BMO|A Chain A, Bm-40, FsEC DOMAIN PAIR
pdb|1BMO|B Chain B, Bm-40, FsEC DOMAIN PAIR
Length = 233
Score = 22.7 bits (47), Expect = 6.3
Identities = 7/19 (36%), Positives = 12/19 (62%)
Query: 29 WCGPCKMLSPVIDELASEY 47
+ GPCK + P +D +E+
Sbjct: 75 YIGPCKYIPPCLDSELTEF 93
>pdb|1IE5|A Chain A, Nmr Structure Of The Third Immunoglobulin Domain From
The Neural Cell Adhesion Molecule
Length = 107
Score = 22.7 bits (47), Expect = 6.3
Identities = 8/14 (57%), Positives = 11/14 (78%)
Query: 74 PTLLFTKDGEVVHQ 87
PT+ +TKDGE + Q
Sbjct: 43 PTMTWTKDGEPIEQ 56
>pdb|1NUB|A Chain A, Helix C Deletion Mutant Of Bm-40 Fs-Ec Domain Pair
pdb|1NUB|B Chain B, Helix C Deletion Mutant Of Bm-40 Fs-Ec Domain Pair
Length = 229
Score = 22.7 bits (47), Expect = 6.3
Identities = 7/19 (36%), Positives = 12/19 (62%)
Query: 29 WCGPCKMLSPVIDELASEY 47
+ GPCK + P +D +E+
Sbjct: 79 YIGPCKYIPPCLDSELTEF 97
>pdb|1URO|A Chain A, Uroporphyrinogen Decarboxylase
Length = 367
Score = 22.3 bits (46), Expect = 8.3
Identities = 11/39 (28%), Positives = 21/39 (53%), Gaps = 8/39 (20%)
Query: 69 GIRSIPTLLFTKDG--------EVVHQLVGVQTKVALKE 99
G+ +P ++F KDG + +++VG+ VA K+
Sbjct: 252 GLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKK 290
>pdb|1G0D|A Chain A, Crystal Structure Of Red Sea Bream Transglutaminase
Length = 695
Score = 22.3 bits (46), Expect = 8.3
Identities = 9/30 (30%), Positives = 14/30 (46%)
Query: 30 CGPCKMLSPVIDELASEYEGKAKICKVNTD 59
CGPC + + L +Y+ +VN D
Sbjct: 368 CGPCPVAAIKEGNLGVKYDAPFVFAEVNAD 397
>pdb|1HSO|A Chain A, Human Alpha Alcohol Dehydrogenase (Adh1a)
pdb|1HSO|B Chain B, Human Alpha Alcohol Dehydrogenase (Adh1a)
Length = 374
Score = 22.3 bits (46), Expect = 8.3
Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 15/80 (18%)
Query: 14 STIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSI 73
+T+K G ++ P CG C++ ++ C N ++S G
Sbjct: 81 TTVKPGDKVIPLAIPQCGKCRICK----------NPESNYCLKN-----DVSNPQGTLQD 125
Query: 74 PTLLFTKDGEVVHQLVGVQT 93
T FT + +H +G+ T
Sbjct: 126 GTSRFTCRRKPIHHFLGIST 145
>pdb|1JPK|A Chain A, Gly156asp Mutant Of Human Urod, Human Uroporphyrinogen Iii
Decarboxylase
Length = 388
Score = 22.3 bits (46), Expect = 8.3
Identities = 11/39 (28%), Positives = 21/39 (53%), Gaps = 8/39 (20%)
Query: 69 GIRSIPTLLFTKDG--------EVVHQLVGVQTKVALKE 99
G+ +P ++F KDG + +++VG+ VA K+
Sbjct: 273 GLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKK 311
>pdb|1JPI|A Chain A, Phe232leu Mutant Of Human Urod, Human Uroporphyrinogen Iii
Decarboxylase
Length = 388
Score = 22.3 bits (46), Expect = 8.3
Identities = 11/39 (28%), Positives = 21/39 (53%), Gaps = 8/39 (20%)
Query: 69 GIRSIPTLLFTKDG--------EVVHQLVGVQTKVALKE 99
G+ +P ++F KDG + +++VG+ VA K+
Sbjct: 273 GLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKK 311
Database: /var/www/html/HP/blast_new/blast/db/pdbaa
Posted date: Dec 20, 2002 11:08 AM
Number of letters in database: 2,899,336
Number of sequences in database: 13,198
Lambda K H
0.316 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 574,895
Number of Sequences: 13198
Number of extensions: 19962
Number of successful extensions: 120
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 50
Number of HSP's gapped (non-prelim): 69
length of query: 106
length of database: 2,899,336
effective HSP length: 82
effective length of query: 24
effective length of database: 1,817,100
effective search space: 43610400
effective search space used: 43610400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 46 (22.3 bits)