BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15644721|ref|NP_206891.1| type II restriction enzyme
R protein (hsdR) [Helicobacter pylori 26695]
         (277 letters)

Database: /var/www/html/HP/blast_new/blast/db/pdbaa
           13,198 sequences; 2,899,336 total letters

Searching...........................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pdb|1CQG|A  Chain A, High Resolution Solution Nmr Structure ...    32  0.080
pdb|1TRS|    Thioredoxin Mutant With Cys 62 Replaced By Ala,...    32  0.080
pdb|1AIU|    Human Thioredoxin (D60n Mutant, Reduced Form)         31  0.18
pdb|1ERW|    Human Thioredoxin Double Mutant With Cys 32 Rep...    30  0.23
pdb|1ERT|    Human Thioredoxin (Reduced Form) >gi|2982059|pd...    30  0.30
pdb|1ERV|    Human Thioredoxin Mutant With Cys 73 Replaced B...    30  0.30
pdb|3TRX|    Thioredoxin (Reduced Form) >gi|231098|pdb|4TRX|...    30  0.40
pdb|1KCW|    X-Ray Crystal Structure Of Human Ceruloplasmin ...    28  1.2
pdb|1EZT|A  Chain A, High-Resolution Solution Structure Of F...    27  3.4
pdb|1AGR|E  Chain E, Complex Of Alf4-Activated Gi-Alpha-1 Wi...    27  3.4
pdb|1DQ3|A  Chain A, Crystal Structure Of An Archaeal Intein...    26  5.7
pdb|1G8X|A  Chain A, Structure Of A Genetically Engineered M...    25  9.8
pdb|1MMG|    X-Ray Structures Of The Mgadp, Mgatpgammas, And...    25  9.8
pdb|1LVK|    X-Ray Crystal Structure Of The Mg (Dot) 2'(3')-...    25  9.8
pdb|1DMT|A  Chain A, Structure Of Human Neutral Endopeptidas...    25  9.8
pdb|1MMN|    X-Ray Structures Of The Mgadp, Mgatpgammas, And...    25  9.8
>pdb|1CQG|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
           Intermediate Between Human Thioredoxin (C35a, C62a,
           C69a, C73a) Mutant And A 13 Residue Peptide Comprising
           Its Target Site In Human Ref-1 (Residues 59 - 71 Of The
           P50 Subunit Of Nfkb), Nmr, 31 Structures
 pdb|1CQH|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
           Intermediate Between Human Thioredoxin (C35a, C62a,
           C69a, C73a) Mutant And A 13 Residue Peptide Comprising
           Its Target Site In Human Ref-1 (Residues 59 - 71 Of The
           P50 Subunit Of Nfkb), Nmr, Minimized Average Structure
 pdb|1MDI|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
           Intermediate Between Mutant Human Thioredoxin And A 13
           Residue Peptide Comprising Its Target Site In Human Nfkb
 pdb|1MDJ|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
           Intermediate Between Human Thioredoxin (C35a, C62a,
           C69a, C73a) Mutant And A 13 Residue Peptide Comprising
           Its Target Site In Human Nfkb (Residues 56-68 Of The P50
           Subunit Of Nfkb)
 pdb|1MDK|A Chain A, High Resolution Solution Nmr Structure Of Mixed Disulfide
           Intermediate Between Human Thioredoxin (C35a, C62a,
           C69a, C73a) Mutant And A 13 Residue Peptide Comprising
           Its Target Site In Human Nfkb (Residues 56-68 Of The P50
           Subunit Of Nfkb)
          Length = 105

 Score = 32.0 bits (71), Expect = 0.080
 Identities = 18/57 (31%), Positives = 31/57 (53%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +A     P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVDDAQDVASEAEVKATPTFQFFKKGQKVGEF 89
>pdb|1TRS|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
           Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Oxidized)
           (Nmr, Minimized Average Structure)
 pdb|1TRU|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
           Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Oxidized)
           (Nmr, 40 Structures)
 pdb|1TRV|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
           Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Reduced)
           (Nmr, 40 Structures)
 pdb|1TRW|   Thioredoxin Mutant With Cys 62 Replaced By Ala, Cys 69 Replaced By
           Ala, Cys 73 Replaced By Ala (C62a,C69a,C73a) (Reduced)
           (Nmr, Minimized Average Structure)
          Length = 105

 Score = 32.0 bits (71), Expect = 0.080
 Identities = 18/57 (31%), Positives = 31/57 (53%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +A     P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVDDAQDVASEAEVKATPTFQFFKKGQKVGEF 89
>pdb|1AIU|   Human Thioredoxin (D60n Mutant, Reduced Form)
          Length = 105

 Score = 30.8 bits (68), Expect = 0.18
 Identities = 17/57 (29%), Positives = 30/57 (51%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +      P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVNDCQDVASECEVKCMPTFQFFKKGQKVGEF 89
>pdb|1ERW|   Human Thioredoxin Double Mutant With Cys 32 Replaced By Ser And
           Cys 35 Replaced By Ser
          Length = 105

 Score = 30.4 bits (67), Expect = 0.23
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 52  TKELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           +K +K    SL ++Y    NV+ + + V D +D+  +      P + +F+ G+KV EF
Sbjct: 35  SKMIKPFFHSLSEKYS---NVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEF 89
>pdb|1ERT|   Human Thioredoxin (Reduced Form)
 pdb|1AUC|   Human Thioredoxin (Oxidized With Diamide)
 pdb|1ERU|   Human Thioredoxin (Oxidized Form)
          Length = 105

 Score = 30.0 bits (66), Expect = 0.30
 Identities = 17/57 (29%), Positives = 30/57 (51%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +      P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEF 89
>pdb|1ERV|   Human Thioredoxin Mutant With Cys 73 Replaced By Ser (Reduced
           Form)
          Length = 105

 Score = 30.0 bits (66), Expect = 0.30
 Identities = 17/57 (29%), Positives = 30/57 (51%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +      P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVDDCQDVASECEVKSMPTFQFFKKGQKVGEF 89
>pdb|3TRX|   Thioredoxin (Reduced Form)
 pdb|4TRX|   Thioredoxin (Reduced Form)
          Length = 105

 Score = 29.6 bits (65), Expect = 0.40
 Identities = 17/57 (29%), Positives = 30/57 (51%), Gaps = 3/57 (5%)

Query: 53  KELKNCIKSLFKEYPKAFNVLNILIAVRDKKDIVLDANGNFYPLYSYFEDGEKVYEF 109
           K +K    SL ++Y    NV+ + + V D +D+  +      P + +F+ G+KV EF
Sbjct: 36  KMIKPFFHSLSEKYS---NVIFLEVDVDDCQDVASECEVKCTPTFQFFKKGQKVGEF 89
>pdb|1KCW|   X-Ray Crystal Structure Of Human Ceruloplasmin At 3.0 Angstroms
          Length = 1046

 Score = 28.1 bits (61), Expect = 1.2
 Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 2/84 (2%)

Query: 184 DDIKKFDFVVCGKDKTYFIEANFYTISGSKLNEVARSYQDLAL--KFEAFPNYEFIWITD 241
           D   K +    G D   F E     I GS    V R Y D +   + E  P  E + I  
Sbjct: 372 DIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILG 431

Query: 242 GIGWLDAKNKLQEAYKSVEIYNLS 265
            + W +  + ++  + +   Y LS
Sbjct: 432 PVIWAEVGDTIRVTFHNKGAYPLS 455
>pdb|1EZT|A Chain A, High-Resolution Solution Structure Of Free Rgs4 By Nmr
 pdb|1EZY|A Chain A, High-Resolution Solution Structure Of Free Rgs4 By Nmr
          Length = 166

 Score = 26.6 bits (57), Expect = 3.4
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 8/79 (10%)

Query: 59  IKSLFKEYPKAFNVLNILIAVRDKKDIVLD-------ANGNFYPLYSYFEDGE-KVYEFI 110
           IKS  K  PKA  + N  I+V+  K++ LD       +     P  + F++ + K++  +
Sbjct: 55  IKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLM 114

Query: 111 RQTGLERIFCNRNIKDLND 129
            +    R   +R   DL +
Sbjct: 115 EKDSYRRFLKSRFYLDLTN 133
>pdb|1AGR|E Chain E, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
 pdb|1AGR|H Chain H, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
          Length = 205

 Score = 26.6 bits (57), Expect = 3.4
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 8/79 (10%)

Query: 59  IKSLFKEYPKAFNVLNILIAVRDKKDIVLD-------ANGNFYPLYSYFEDGE-KVYEFI 110
           IKS  K  PKA  + N  I+V+  K++ LD       +     P  + F++ + K++  +
Sbjct: 101 IKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLM 160

Query: 111 RQTGLERIFCNRNIKDLND 129
            +    R   +R   DL +
Sbjct: 161 EKDSYRRFLKSRFYLDLTN 179
>pdb|1DQ3|A Chain A, Crystal Structure Of An Archaeal Intein-Encoded Homing
           Endonuclease Pi-Pfui
          Length = 454

 Score = 25.8 bits (55), Expect = 5.7
 Identities = 17/83 (20%), Positives = 34/83 (40%), Gaps = 7/83 (8%)

Query: 105 KVYEFIRQTGLERIFCNRNIKDLNDFVFGIEVGLDSNARKNRSGKVMENHLSGLFTNAQL 164
           ++ E +R+ G++ +        L  F   I   L +  ++ +  KV+ NH  G       
Sbjct: 284 RIREKLRKDGIDYVLHVEEYSSLLRFYELIGKNLQNEEKREKLEKVLSNHKGG------- 336

Query: 165 NFKEQVEIREFEDLCQAFGDDIK 187
           NF   +    F++    +G + K
Sbjct: 337 NFGLPLNFNAFKEWASEYGVEFK 359
>pdb|1G8X|A Chain A, Structure Of A Genetically Engineered Molecular Motor
 pdb|1G8X|B Chain B, Structure Of A Genetically Engineered Molecular Motor
          Length = 1010

 Score = 25.0 bits (53), Expect = 9.8
 Identities = 14/43 (32%), Positives = 25/43 (57%), Gaps = 3/43 (6%)

Query: 186 IKKFDFVVCGKDKTYFIEANFYTISGSKLNEVARSYQDLALKF 228
           +KK + V+C + K YFI      ISG ++ +V  S++ L + +
Sbjct: 434 VKKINNVLCSERKAYFI--GVLDISGFEIFKV-NSFEQLCINY 473
>pdb|1MMG|   X-Ray Structures Of The Mgadp, Mgatpgammas, And Mgamppnp Complexes
           Of The Dictyostelium Discoideum Myosin Motor Domain
          Length = 762

 Score = 25.0 bits (53), Expect = 9.8
 Identities = 14/43 (32%), Positives = 25/43 (57%), Gaps = 3/43 (6%)

Query: 186 IKKFDFVVCGKDKTYFIEANFYTISGSKLNEVARSYQDLALKF 228
           +KK + V+C + K YFI      ISG ++ +V  S++ L + +
Sbjct: 434 VKKINNVLCSERKAYFI--GVLDISGFEIFKV-NSFEQLCINY 473
>pdb|1LVK|   X-Ray Crystal Structure Of The Mg (Dot)
           2'(3')-O-(N-Methylanthraniloyl) Nucleotide Bound To
           Dictyostelium Discoideum Myosin Motor Domain
          Length = 762

 Score = 25.0 bits (53), Expect = 9.8
 Identities = 14/43 (32%), Positives = 25/43 (57%), Gaps = 3/43 (6%)

Query: 186 IKKFDFVVCGKDKTYFIEANFYTISGSKLNEVARSYQDLALKF 228
           +KK + V+C + K YFI      ISG ++ +V  S++ L + +
Sbjct: 434 VKKINNVLCSERKAYFI--GVLDISGFEIFKV-NSFEQLCINY 473
>pdb|1DMT|A Chain A, Structure Of Human Neutral Endopeptidase Complexed With
           Phosphoramidon
          Length = 696

 Score = 25.0 bits (53), Expect = 9.8
 Identities = 20/78 (25%), Positives = 34/78 (42%), Gaps = 10/78 (12%)

Query: 209 ISGSKLNEVARSYQDLALKFEAFPNYE---------FIWITDGIGWLDAKNKLQEAYKSV 259
           ++G+  N V R Y + A   E+    E         FI   D + W+DA+ K +   K++
Sbjct: 361 VNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKAL 420

Query: 260 EI-YNLSNVNDFISKAQK 276
            I   +   +D +S   K
Sbjct: 421 AIKERIGYPDDIVSNDNK 438
>pdb|1MMN|   X-Ray Structures Of The Mgadp, Mgatpgammas, And Mgamppnp Complexes
           Of The Dictyostelium Discoideum Myosin Motor Domain
          Length = 762

 Score = 25.0 bits (53), Expect = 9.8
 Identities = 14/43 (32%), Positives = 25/43 (57%), Gaps = 3/43 (6%)

Query: 186 IKKFDFVVCGKDKTYFIEANFYTISGSKLNEVARSYQDLALKF 228
           +KK + V+C + K YFI      ISG ++ +V  S++ L + +
Sbjct: 434 VKKINNVLCSERKAYFI--GVLDISGFEIFKV-NSFEQLCINY 473
  Database: /var/www/html/HP/blast_new/blast/db/pdbaa
    Posted date:  Dec 20, 2002 11:08 AM
  Number of letters in database: 2,899,336
  Number of sequences in database:  13,198
  
Lambda     K      H
   0.322    0.140    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,642,484
Number of Sequences: 13198
Number of extensions: 70507
Number of successful extensions: 214
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 207
Number of HSP's gapped (non-prelim): 16
length of query: 277
length of database: 2,899,336
effective HSP length: 87
effective length of query: 190
effective length of database: 1,751,110
effective search space: 332710900
effective search space used: 332710900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 53 (25.0 bits)