BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15645544|ref|NP_207720.1| GTP cyclohydrolase I (folE)
[Helicobacter pylori 26695]
         (180 letters)

Database: /var/www/html/HP/blast_new/blast/db/pdbaa
           13,198 sequences; 2,899,336 total letters

Searching...........................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pdb|1IS7|A  Chain A, Crystal Structure Of Rat GtpchiGFRP STI...   178  4e-46
pdb|1FB1|A  Chain A, Crystal Structure Of Human Gtp Cyclohyd...   176  2e-45
pdb|1FBX|A  Chain A, Crystal Structure Of Zinc-Containing E....   103  9e-24
pdb|1A8R|A  Chain A, Gtp Cyclohydrolase I (H112s Mutant) In ...   100  1e-22
pdb|1A9C|A  Chain A, Gtp Cyclohydrolase I (C110s Mutant) In ...   100  1e-22
pdb|1K9X|A  Chain A, Structure Of Pyrococcus Furiosus Carbox...    25  4.0

>pdb|1IS7|A Chain A, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|B Chain B, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|C Chain C, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|D Chain D, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|E Chain E, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|F Chain F, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|G Chain G, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|H Chain H, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|I Chain I, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS7|J Chain J, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
 pdb|1IS8|A Chain A, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|B Chain B, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|C Chain C, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|D Chain D, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|E Chain E, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|F Chain F, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|G Chain G, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|H Chain H, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|I Chain I, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
 pdb|1IS8|J Chain J, Crystal Structure Of Rat GtpchiGFRP STIMULATORY COMPLEX
           Plus Zn
          Length = 230

 Score =  178 bits (451), Expect = 4e-46
 Identities = 82/176 (46%), Positives = 122/176 (68%)

Query: 5   FNQFFESIGEDKNREGLKETPKRVQELWKFLYKGYKEDPRVALKSAYFQGVCDEMIVAQN 64
           ++    S+GED  R+GL +TP R     +F  KGY+E     L  A F    DEM++ ++
Sbjct: 55  YSSILRSLGEDPQRQGLLKTPWRAATAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKD 114

Query: 65  IEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTIQIAETFD 124
           I+ +S CEHHL+PF+G + +GY+P ++++G+S +A+++EIYSRRLQ+QERLT QIA    
Sbjct: 115 IDMFSMCEHHLVPFVGRVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAIT 174

Query: 125 EIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDSKTRAEFMQLLKS 180
           E ++P GV VV EA H+CM M+GVQK N+   TS + G+F++D KTR EF+ L++S
Sbjct: 175 EALQPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS 230



>pdb|1FB1|A Chain A, Crystal Structure Of Human Gtp Cyclohydrolase I
 pdb|1FB1|B Chain B, Crystal Structure Of Human Gtp Cyclohydrolase I
 pdb|1FB1|C Chain C, Crystal Structure Of Human Gtp Cyclohydrolase I
 pdb|1FB1|D Chain D, Crystal Structure Of Human Gtp Cyclohydrolase I
 pdb|1FB1|E Chain E, Crystal Structure Of Human Gtp Cyclohydrolase I
          Length = 196

 Score =  176 bits (445), Expect = 2e-45
 Identities = 81/176 (46%), Positives = 121/176 (68%)

Query: 5   FNQFFESIGEDKNREGLKETPKRVQELWKFLYKGYKEDPRVALKSAYFQGVCDEMIVAQN 64
           ++    S+GE+  R+GL +TP R     +F  KGY+E     L  A F    DEM++ ++
Sbjct: 21  YSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKD 80

Query: 65  IEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTIQIAETFD 124
           I+ +S CEHHL+PF+G + +GY+P ++++G+S +A+++EIYSRRLQ+QERLT QIA    
Sbjct: 81  IDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAIT 140

Query: 125 EIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDSKTRAEFMQLLKS 180
           E + P GV VV EA H+CM M+GVQK N+   TS + G+F++D KTR EF+ L++S
Sbjct: 141 EALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS 196



>pdb|1FBX|A Chain A, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|B Chain B, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|C Chain C, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|D Chain D, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|E Chain E, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|F Chain F, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|G Chain G, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|H Chain H, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|I Chain I, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|J Chain J, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|K Chain K, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|L Chain L, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|M Chain M, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|N Chain N, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1FBX|O Chain O, Crystal Structure Of Zinc-Containing E.Coli Gtp
           Cyclohydrolase I
 pdb|1GTP|A Chain A, Gtp Cyclohydrolase I
 pdb|1GTP|B Chain B, Gtp Cyclohydrolase I
 pdb|1GTP|C Chain C, Gtp Cyclohydrolase I
 pdb|1GTP|D Chain D, Gtp Cyclohydrolase I
 pdb|1GTP|E Chain E, Gpp Cyclohydrolase I
 pdb|1GTP|F Chain F, Gtp Cyclohydrolase I
 pdb|1GTP|G Chain G, Gtp Cyclohydrolase I
 pdb|1GTP|H Chain H, Gtp Cyclohydrolase I
 pdb|1GTP|I Chain I, Gtp Cyclohydrolase I
 pdb|1GTP|J Chain J, Gtp Cyclohydrolase I
 pdb|1GTP|K Chain K, Gtp Cyclohydrolase I
 pdb|1GTP|L Chain L, Gtp Cyclohydrolase I
 pdb|1GTP|M Chain M, Gtp Cyclohydrolase I
 pdb|1GTP|N Chain N, Gtp Cyclohydrolase I
 pdb|1GTP|O Chain O, Gtp Cyclohydrolase I
 pdb|1GTP|P Chain P, Gtp Cyclohydrolase I
 pdb|1GTP|Q Chain Q, Gtp Cyclohydrolase I
 pdb|1GTP|R Chain R, Gtp Cyclohydrolase I
 pdb|1GTP|S Chain S, Gtp Cyclohydrolase I
 pdb|1GTP|T Chain T, Gtp Cyclohydrolase I
          Length = 221

 Score =  103 bits (258), Expect = 9e-24
 Identities = 54/176 (30%), Positives = 95/176 (53%), Gaps = 5/176 (2%)

Query: 7   QFFESIGEDKNREGLKETPKRVQELWK---FLYKGYKEDPRVALKSAYFQGVCDEMIVAQ 63
           +  + +  D   + L ETP R+ +++    F    Y   P++ L     +   DEM+  +
Sbjct: 45  EIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMK--VDEMVTVR 102

Query: 64  NIEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTIQIAETF 123
           +I   STCEHH +   G  +V YIPK+ ++G+S I ++++ +++R Q+QERLT QI    
Sbjct: 103 DITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIAL 162

Query: 124 DEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDSKTRAEFMQLLK 179
             ++    V V  +A H C+  +G++   +   T+ L GLFK    TR EF++ ++
Sbjct: 163 QTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVR 218



>pdb|1A8R|A Chain A, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|B Chain B, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|C Chain C, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|D Chain D, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|E Chain E, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|F Chain F, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|G Chain G, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|H Chain H, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|I Chain I, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|J Chain J, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|K Chain K, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|L Chain L, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|M Chain M, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|N Chain N, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
 pdb|1A8R|O Chain O, Gtp Cyclohydrolase I (H112s Mutant) In Complex With Gtp
          Length = 221

 Score =  100 bits (249), Expect = 1e-22
 Identities = 53/176 (30%), Positives = 94/176 (53%), Gaps = 5/176 (2%)

Query: 7   QFFESIGEDKNREGLKETPKRVQELWK---FLYKGYKEDPRVALKSAYFQGVCDEMIVAQ 63
           +  + +  D   + L ETP R+ +++    F    Y   P++ L     +   DEM+  +
Sbjct: 45  EIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMK--VDEMVTVR 102

Query: 64  NIEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTIQIAETF 123
           +I   STCE H +   G  +V YIPK+ ++G+S I ++++ +++R Q+QERLT QI    
Sbjct: 103 DITLTSTCESHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIAL 162

Query: 124 DEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDSKTRAEFMQLLK 179
             ++    V V  +A H C+  +G++   +   T+ L GLFK    TR EF++ ++
Sbjct: 163 QTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVR 218



>pdb|1A9C|A Chain A, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|B Chain B, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|C Chain C, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|D Chain D, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|E Chain E, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|F Chain F, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|G Chain G, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|H Chain H, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|I Chain I, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|J Chain J, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|K Chain K, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|L Chain L, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|M Chain M, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|N Chain N, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
 pdb|1A9C|O Chain O, Gtp Cyclohydrolase I (C110s Mutant) In Complex With Gtp
          Length = 221

 Score =  100 bits (248), Expect = 1e-22
 Identities = 53/176 (30%), Positives = 94/176 (53%), Gaps = 5/176 (2%)

Query: 7   QFFESIGEDKNREGLKETPKRVQELWK---FLYKGYKEDPRVALKSAYFQGVCDEMIVAQ 63
           +  + +  D   + L ETP R+ +++    F    Y   P++ L     +   DEM+  +
Sbjct: 45  EIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMK--VDEMVTVR 102

Query: 64  NIEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTIQIAETF 123
           +I   ST EHH +   G  +V YIPK+ ++G+S I ++++ +++R Q+QERLT QI    
Sbjct: 103 DITLTSTSEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIAL 162

Query: 124 DEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDSKTRAEFMQLLK 179
             ++    V V  +A H C+  +G++   +   T+ L GLFK    TR EF++ ++
Sbjct: 163 QTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVR 218



>pdb|1K9X|A Chain A, Structure Of Pyrococcus Furiosus Carboxypeptidase Apo-Yb
 pdb|1K9X|B Chain B, Structure Of Pyrococcus Furiosus Carboxypeptidase Apo-Yb
 pdb|1K9X|C Chain C, Structure Of Pyrococcus Furiosus Carboxypeptidase Apo-Yb
 pdb|1K9X|D Chain D, Structure Of Pyrococcus Furiosus Carboxypeptidase Apo-Yb
 pdb|1KA2|A Chain A, Structure Of Pyrococcus Furiosus Carboxypeptidase Apo-Mg
 pdb|1KA4|A Chain A, Structure Of Pyrococcus Furiosus Carboxypeptidase Nat-Pb
          Length = 499

 Score = 25.4 bits (54), Expect = 4.0
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 5/56 (8%)

Query: 36  YKGYKEDPRVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFLGNI-SVGYIPKE 90
           Y GY+E+P  AL   Y +G+    +     + +   E  L P L  I   G +P+E
Sbjct: 148 YLGYEEEPYDALLDLYEEGLRTRDVE----KMFEVLEKKLKPLLDKILEEGKVPRE 199



  Database: /var/www/html/HP/blast_new/blast/db/pdbaa
    Posted date:  Dec 20, 2002 11:08 AM
  Number of letters in database: 2,899,336
  Number of sequences in database:  13,198
  
Lambda     K      H
   0.322    0.139    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 945,860
Number of Sequences: 13198
Number of extensions: 34380
Number of successful extensions: 76
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 71
Number of HSP's gapped (non-prelim): 6
length of query: 180
length of database: 2,899,336
effective HSP length: 82
effective length of query: 98
effective length of database: 1,817,100
effective search space: 178075800
effective search space used: 178075800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 51 (24.3 bits)