BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15645904|ref|NP_208083.1| conserved hypothetical
protein [Helicobacter pylori 26695]
         (204 letters)

Database: /home/scwang/download_20020708_db/nr
           1,026,957 sequences; 324,149,939 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_208083.1|  (NC_000915) conserved hypothetical protein...   405  e-112
ref|NP_223929.1|  (NC_000921) putative [Helicobacter pylori ...   377  e-104
ref|NP_562651.1|  (NC_003366) conserved hypothetical protein...    83  2e-15
ref|NP_348357.1|  (NC_003030) Predicted nucleotide-binding p...    78  5e-14
ref|NP_623111.1|  (NC_003869) Thiamine pyrophosphokinase [Th...    72  5e-12
ref|NP_387356.1|  (NC_003047) CONSERVED HYPOTHETICAL PROTEIN...    46  3e-04
ref|NP_603787.1|  (NC_003454) Thiamin pyrophosphokinase [Fus...    43  0.002
ref|NP_593291.1|  (NC_003424) thiamine pyrophosphokinase [Sc...    42  0.003
>ref|NP_208083.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
           26695]
 pir||C64681 conserved hypothetical protein HP1291 - Helicobacter pylori
           (strain 26695)
 gb|AAD08334.1| (AE000633) conserved hypothetical protein [Helicobacter pylori
           26695]
          Length = 204

 Score =  405 bits (1041), Expect = e-112
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA
Sbjct: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60

Query: 61  LYNPIRMSEQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYFKFCQKI 120
           LYNPIRMSEQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYFKFCQKI
Sbjct: 61  LYNPIRMSEQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYFKFCQKI 120

Query: 121 QAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKAQFTSKNLKYPLKNLRLKTLFSGSLN 180
           QAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKAQFTSKNLKYPLKNLRLKTLFSGSLN
Sbjct: 121 QAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKAQFTSKNLKYPLKNLRLKTLFSGSLN 180

Query: 181 EATDSYFSLSSTPKSVVLVYQKFL 204
           EATDSYFSLSSTPKSVVLVYQKFL
Sbjct: 181 EATDSYFSLSSTPKSVVLVYQKFL 204
>ref|NP_223929.1| (NC_000921) putative [Helicobacter pylori J99]
 pir||C71832 hypothetical protein jhp1211 - Helicobacter pylori (strain J99)
 gb|AAD06813.1| (AE001547) putative [Helicobacter pylori J99]
          Length = 204

 Score =  377 bits (967), Expect = e-104
 Identities = 187/203 (92%), Positives = 199/203 (97%)

Query: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           MQAVILANGEFPKS+KCLD+L+NAPFLIACDGAV SLHALQFKPSVVIGDLDSIDSHLKA
Sbjct: 1   MQAVILANGEFPKSKKCLDILQNAPFLIACDGAVISLHALQFKPSVVIGDLDSIDSHLKA 60

Query: 61  LYNPIRMSEQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYFKFCQKI 120
           LYNPIR+SEQ+SNDLSKAFFYALN+GCDDFIFLGLNGKREDHALANTFLLLEYFKFC+KI
Sbjct: 61  LYNPIRVSEQDSNDLSKAFFYALNRGCDDFIFLGLNGKREDHALANTFLLLEYFKFCKKI 120

Query: 121 QAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKAQFTSKNLKYPLKNLRLKTLFSGSLN 180
           Q++SDYGLFRVLETPFTLPSFKGEQISLFSLDLKA+FTSKNLKYPLK+LRLKTLFSGSLN
Sbjct: 121 QSVSDYGLFRVLETPFTLPSFKGEQISLFSLDLKARFTSKNLKYPLKDLRLKTLFSGSLN 180

Query: 181 EATDSYFSLSSTPKSVVLVYQKF 203
           EAT+  FSLSS PKSVVLVYQKF
Sbjct: 181 EATNHCFSLSSEPKSVVLVYQKF 203
>ref|NP_562651.1| (NC_003366) conserved hypothetical protein [Clostridium
           perfringens]
 dbj|BAB81441.1| (AP003191) conserved hypothetical protein [Clostridium perfringens]
          Length = 209

 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 63/210 (30%), Positives = 95/210 (45%), Gaps = 10/210 (4%)

Query: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           M+ +I+A GE P S+     +K    LIA D    +     F P   +GD DSI    K 
Sbjct: 1   MKVLIIAGGEKPSSELLKSEIKECDLLIAADRGAEAYLENGFTPDYALGDFDSIGEEYKD 60

Query: 61  LYNPIRMS----EQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYFKF 116
           + + I++     E+++ D   AFF A+  G  + +FLG+ G R DH +AN  LL E  + 
Sbjct: 61  ILDKIKVEKFNPEKDNTDTEIAFFKAVELGATEIVFLGVTGTRLDHVMANLGLLREALER 120

Query: 117 CQKIQAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKA-QFTSKNLKYPLKNLRLKTLF 175
             +   I +     +     TL    G+ IS  +       F+ K  KY L N +L  L 
Sbjct: 121 GIEAYIIDNNNKIYLKNKETTLKKEFGDYISFQAFGSPVNNFSIKGSKYELYNHKL--LI 178

Query: 176 SGSL---NEATDSYFSLSSTPKSVVLVYQK 202
             SL   NE  D Y  +S     V+++Y +
Sbjct: 179 GDSLCVSNEFNDEYIDISFEKGEVLVIYSR 208
>ref|NP_348357.1| (NC_003030) Predicted nucleotide-binding protein, YLOS B.subtilis
           ortholog [Clostridium acetobutylicum]
 gb|AAK79697.1|AE007682_7 (AE007682) Predicted nucleotide-binding protein, YLOS B.subtilis
           ortholog [Clostridium acetobutylicum]
          Length = 211

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 53/208 (25%), Positives = 96/208 (45%), Gaps = 10/208 (4%)

Query: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           M+ V+++ G+ P        ++N  ++I  D     LH  + +P +++GD DSID  +  
Sbjct: 1   MKVVVISGGKMPSEALLRSEIENCDYIICADSGANCLHKYEIRPDMLLGDFDSIDEEVFN 60

Query: 61  LYNPIRMS------EQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYF 114
            +    ++      E++  D   AF  AL    D+  FLG  G R DH   N  LL    
Sbjct: 61  YFKEFHINTIKFPREKDFTDTELAFREALKLSADEICFLGCTGTRLDHIFGNLGLLYRCL 120

Query: 115 KFCQKIQAISDYGLFRVLETPFTLPSFKGEQISL--FSLDLKAQFTSKNLKYPLKNLRLK 172
           K   +     D     +++   ++   KGE  S+  F  ++K + + +N KYPLK+  L 
Sbjct: 121 KSGIRAYIKDDNNTLFMIDKTISITGKKGEIFSIQGFREEIK-ELSIENAKYPLKDYNLS 179

Query: 173 TLFSGSL-NEATDSYFSLSSTPKSVVLV 199
              S ++ NE  D   ++S    +++++
Sbjct: 180 FGDSRTVSNEFLDEPVTISFKNGTIIVM 207
>ref|NP_623111.1| (NC_003869) Thiamine pyrophosphokinase [Thermoanaerobacter
           tengcongensis]
 gb|AAM24715.1| (AE013107) Thiamine pyrophosphokinase [Thermoanaerobacter
           tengcongensis]
          Length = 211

 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 48/174 (27%), Positives = 87/174 (49%), Gaps = 9/174 (5%)

Query: 1   MQAVILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           M+ +I++NGE        ++++    +I  DG     + ++ +P ++IGD DS+D  +  
Sbjct: 1   MKVLIISNGEIKDYGFYKNIVEEVDMVICADGGANHAYKMKIRPFLIIGDFDSVDREVLE 60

Query: 61  LYNP--IRMSE----QNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYF 114
            Y    +++ +    ++  D   A   A+  G  D  F+G+ G R DH+ AN  LLL   
Sbjct: 61  FYQKEGVKVEKFPTMKDETDTQLALKKAIELGAKDITFIGVIGDRFDHSYANLSLLLYSL 120

Query: 115 KFCQKIQAISDYGLFRVLETPFTLPSFKGEQISL--FSLDLKAQFTSKNLKYPL 166
           K   K + I++     +++    +   KGE +SL  +S ++K  +T K L YPL
Sbjct: 121 KRGVKSRIINEKNEIHLIDDYIEIEGKKGELLSLLPYSGEVKGIYT-KGLFYPL 173
>ref|NP_387356.1| (NC_003047) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
 emb|CAC47829.1| (AL591793) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
          Length = 216

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 11/188 (5%)

Query: 5   ILANGEFPKSQKCLDLLKNAPFLIACDGAVTSLHALQFKPSVVIGDLDSIDSHLKALYNP 64
           IL  G    + +    L+ + F +A DG +     L   P + +GD DS D  L A +  
Sbjct: 8   ILLGGALTPTDRLARQLEGSRF-VAADGGMRHARTLGVVPDLWVGDFDSTDEALLAEFAG 66

Query: 65  I----RMSEQNSNDLSKAFFYALNKGCDDFIFL-GLNGKREDHA---LANTFLLLEYFKF 116
           +      + +N+ D   A   AL +G    +F  GL G R DHA   L  T  L E    
Sbjct: 67  VPRERHPAAKNATDGEIAVEAALERGATSLVFAGGLGGARSDHAFLHLLGTVALAE--SG 124

Query: 117 CQKIQAISDYGLFRVLETPFTLPSFKGEQISLFSLDLKAQFTSKNLKYPLKNLRLKTLFS 176
              +    +   + +L     +   KG   S+         + +N++YPLK+  L    S
Sbjct: 125 VAVMMTSGEEEAYPLLPGSQEIELPKGSLFSILGFADLDGLSIENVRYPLKDFHLPFGSS 184

Query: 177 GSLNEATD 184
            +++   D
Sbjct: 185 RTISNIAD 192
>ref|NP_603787.1| (NC_003454) Thiamin pyrophosphokinase [Fusobacterium nucleatum
           subsp. nucleatum ATCC 25586]
 gb|AAL95086.1| (AE010597) Thiamin pyrophosphokinase [Fusobacterium nucleatum
           subsp. nucleatum ATCC 25586]
          Length = 209

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 50/180 (27%), Positives = 73/180 (39%), Gaps = 16/180 (8%)

Query: 3   AVILANGEFPKSQKC-LDLLKNAPFLIAC-DGAVTSLHALQFKPSVVIGDLDSIDSHLKA 60
           A +  NGE    +   LD +KN    I C DG     + L   P  + GDLDSI   +K 
Sbjct: 4   AYLFLNGELRGDKNFYLDFIKNHKGDIYCADGGANFCYELTLIPKEIYGDLDSIKDEVKE 63

Query: 61  LYNPIRMS------EQNSNDLSKAFFYALNKGCDDFIFLGLNGKREDHALANTFLLLEYF 114
            Y   ++       E++  D         NK    +   GL G   DH L N  LL +Y 
Sbjct: 64  FYQEKKVKFIKFKIEKDYTDSELLLNEIQNKYDVIYCIAGLGGS-IDHELTNINLLAKY- 121

Query: 115 KFCQKIQAISDYGLFRVLETPFTLPSFKGEQIS--LFSLDLKAQFTSKNLKYPLKNLRLK 172
                +  IS+      +++          +IS  +FS  +K   T K  KY ++NL +K
Sbjct: 122 ---SNLIFISEKEKIFKIDSDSKFNDMINTKISFVIFSDQVKG-LTLKGFKYSIENLDIK 177
>ref|NP_593291.1| (NC_003424) thiamine pyrophosphokinase [Schizosaccharomyces pombe]
 sp|P41888|TNR3_SCHPO Thiamine pyrophosphokinase (TPK) (Thiamine kinase)
 pir||S52350 thiamin pyrophosphokinase (EC 2.7.6.2) - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA59135.1| (X84417) thiamin pyrophosphokinase [Schizosaccharomyces pombe]
 emb|CAB11089.1| (Z98533) thiamine pyrophosphokinase [Schizosaccharomyces pombe]
          Length = 569

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 29/94 (30%), Positives = 38/94 (39%), Gaps = 7/94 (7%)

Query: 20  LLKNAPFLIACDGAVTSL--HALQFKPSVVIGDLDSIDSHLKALYNPIRMSE-----QNS 72
           L K A   +  DG    L  +    KP  V+GD DS+    KA Y  + ++      QN+
Sbjct: 372 LWKRASIRVCADGGANQLRNYDSSLKPDYVVGDFDSLTDETKAYYKEMGVNIVFDPCQNT 431

Query: 73  NDLSKAFFYALNKGCDDFIFLGLNGKREDHALAN 106
            D  K        G D    L   G R DHA+ N
Sbjct: 432 TDFMKCHKIIKEHGIDTIFVLCGMGGRVDHAIGN 465
  Database: /home/scwang/download_20020708_db/nr
    Posted date:  Aug 7, 2002 12:55 PM
  Number of letters in database: 324,149,939
  Number of sequences in database:  1,026,957
  
Lambda     K      H
   0.322    0.138    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,497,872
Number of Sequences: 1026957
Number of extensions: 4743021
Number of successful extensions: 9088
Number of sequences better than 1.0e-02: 8
Number of HSP's better than  0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 9079
Number of HSP's gapped (non-prelim): 8
length of query: 204
length of database: 324,149,939
effective HSP length: 115
effective length of query: 89
effective length of database: 206,049,884
effective search space: 18338439676
effective search space used: 18338439676
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 94 (40.8 bits)