BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15645951|ref|NP_208130.1| conserved hypothetical
protein [Helicobacter pylori 26695]
(148 letters)
Database: /home/scwang/download_20020708_db/nr
1,026,957 sequences; 324,149,939 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_208130.1| (NC_000915) conserved hypothetical protein... 299 6e-81
ref|NP_223975.1| (NC_000921) putative [Helicobacter pylori ... 292 6e-79
ref|NP_621942.1| (NC_003869) predicted Transcriptional regu... 114 3e-25
ref|NP_069577.1| (NC_000917) conserved hypothetical protein... 105 1e-22
ref|NP_661372.1| (NC_002932) conserved hypothetical protein... 105 1e-22
ref|NP_578051.1| (NC_003413) hypothetical protein [Pyrococc... 105 2e-22
ref|NP_127117.1| (NC_000868) hypothetical protein [Pyrococc... 104 3e-22
ref|NP_618943.1| (NC_003552) transcriptional regulator, Cop... 103 5e-22
ref|NP_142565.1| (NC_000961) hypothetical protein [Pyrococc... 103 7e-22
ref|NP_632866.1| (NC_003901) conserved protein [Methanosarc... 103 7e-22
ref|NP_616331.1| (NC_003552) transcriptional regulator, Cop... 96 1e-19
ref|NP_632690.1| (NC_003901) putative nickel-responsive reg... 95 2e-19
ref|NP_247528.1| (NC_000909) conserved hypothetical protein... 95 2e-19
ref|NP_275882.1| (NC_000916) conserved protein [Methanother... 94 3e-19
ref|NP_614785.1| (NC_003551) Predicted transcriptional regu... 89 2e-17
ref|NP_616689.1| (NC_003552) transcriptional regulator, Cop... 84 3e-16
ref|NP_617713.1| (NC_003552) transcriptional regulator, Cop... 83 7e-16
ref|NP_634681.1| (NC_003901) transcriptional regulator [Met... 82 2e-15
ref|NP_458337.1| (NC_003198) nickel responsive regulator [S... 79 2e-14
ref|NP_290047.1| (NC_002655) orf, hypothetical protein [Esc... 78 2e-14
ref|NP_342174.1| (NC_002754) Conserved hypothetical protein... 68 3e-11
sp|Q9AL83|NIKR_BRUSU Nickel responsive regulator >gi|123311... 66 9e-11
ref|NP_541464.1| (NC_003318) Nickel-responsive regulator Ni... 64 5e-10
sp|Q8YCP2|NIKR_BRUME Nickel responsive regulator 64 5e-10
ref|NP_279286.1| (NC_002607) Vng0147c [Halobacterium sp. NR... 62 2e-09
sp|Q9HSN7|NIKR_HALN1 Putative nickel responsive regulator 62 2e-09
ref|NP_247752.1| (NC_000909) conserved hypothetical protein... 57 6e-08
ref|NP_275746.1| (NC_000916) conserved protein [Methanother... 50 7e-06
ref|NP_377483.1| (NC_003106) 127aa long conserved hypotheti... 44 6e-04
ref|NP_420633.1| (NC_002696) conserved hypothetical protein... 40 0.007
>ref|NP_208130.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
26695]
sp|O25896|NIKR_HELPY Putative nickel responsive regulator
pir||B64687 conserved hypothetical protein HP1338 - Helicobacter pylori
(strain 26695)
gb|AAD08380.1| (AE000635) conserved hypothetical protein [Helicobacter pylori
26695]
Length = 148
Score = 299 bits (765), Expect = 6e-81
Identities = 148/148 (100%), Positives = 148/148 (100%)
Query: 1 MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPN 60
MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPN
Sbjct: 1 MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPN 60
Query: 61 DESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEI 120
DESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEI
Sbjct: 61 DESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEI 120
Query: 121 QRLQLEIGGLRGVKFAKLTKASSFEYNE 148
QRLQLEIGGLRGVKFAKLTKASSFEYNE
Sbjct: 121 QRLQLEIGGLRGVKFAKLTKASSFEYNE 148
>ref|NP_223975.1| (NC_000921) putative [Helicobacter pylori J99]
sp|Q9ZJP7|NIKR_HELPJ Putative nickel responsive regulator
pir||C71829 hypothetical protein jhp1257 - Helicobacter pylori (strain J99)
gb|AAD06843.1| (AE001549) putative [Helicobacter pylori J99]
Length = 148
Score = 292 bits (748), Expect = 6e-79
Identities = 145/148 (97%), Positives = 145/148 (97%)
Query: 1 MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPN 60
MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNW EDNPN
Sbjct: 1 MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWVEDNPN 60
Query: 61 DESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEI 120
D SKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNS EI
Sbjct: 61 DGSKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSLEI 120
Query: 121 QRLQLEIGGLRGVKFAKLTKASSFEYNE 148
QRLQLEIGGLRGVKFAKLTKASSFEYNE
Sbjct: 121 QRLQLEIGGLRGVKFAKLTKASSFEYNE 148
>ref|NP_621942.1| (NC_003869) predicted Transcriptional regulator containing the
CopG/Arc/MetJ DNA-binding domain and a metal-binding
domain [Thermoanaerobacter tengcongensis]
gb|AAM23546.1| (AE012997) predicted Transcriptional regulator containing the
CopG/Arc/MetJ DNA-binding domain and a metal-binding
domain [Thermoanaerobacter tengcongensis]
Length = 154
Score = 114 bits (285), Expect = 3e-25
Identities = 52/138 (37%), Positives = 87/138 (62%), Gaps = 3/138 (2%)
Query: 8 DSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAV 67
+ I+RF VS++ LL + D I K Y++RSE +RD+IR+ +VE+ W + D I
Sbjct: 18 EGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIVENQWEAE---DVETIGT 74
Query: 68 LVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEI 127
+ +++H RE+N ++ D+QH +++ T H+H+DEHNC+E +I++G + EI ++ EI
Sbjct: 75 ITYVFNHEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIVRGKAKEIVKIADEI 134
Query: 128 GGLRGVKFAKLTKASSFE 145
RGVK KL ++ E
Sbjct: 135 ISTRGVKHGKLVMTTTGE 152
>ref|NP_069577.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
sp|O29515|NIKR_ARCFU Putative nickel responsive regulator
pir||G69342 conserved hypothetical protein AF0743 - Archaeoglobus fulgidus
gb|AAB90499.1| (AE001054) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 138
Score = 105 bits (263), Expect = 1e-22
Identities = 57/135 (42%), Positives = 79/135 (58%), Gaps = 2/135 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
++ I R VSL +NLLDE D I GYSSRSE +RD IR + E W E + +
Sbjct: 2 EEGITRIGVSLPKNLLDEFDRIISTRGYSSRSEAIRDAIRTYITEYRWLESEKGEI--VG 59
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
VLVV+YDHH + ++ +ID+QH + +THIH++E CLE I+++G I+ L +
Sbjct: 60 VLVVLYDHHVKGVSDLLIDLQHDFHEIITSSTHIHLNEDQCLEMILVKGKMERIKVLVDK 119
Query: 127 IGGLRGVKFAKLTKA 141
I RGV KL A
Sbjct: 120 ISAARGVMNVKLISA 134
>ref|NP_661372.1| (NC_002932) conserved hypothetical protein [Chlorobium tepidum TLS]
gb|AAM71714.1| (AE012823) conserved hypothetical protein [Chlorobium tepidum TLS]
Length = 134
Score = 105 bits (263), Expect = 1e-22
Identities = 54/134 (40%), Positives = 82/134 (60%), Gaps = 4/134 (2%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
+ RF +SL++ L++ D I GY SRSE +RD+IRE+L+ AE +V
Sbjct: 4 LYRFGISLERKLIESFDRHIKAQGYQSRSEALRDLIREELLRKTTAEGG----LVAGAIV 59
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
+ YDHH+R+L R+IDIQH ++ T H+H+D NCLE I ++GN+ EI++L +
Sbjct: 60 MTYDHHKRDLVNRLIDIQHDFHDLIISTQHVHLDHENCLEVIAVKGNAPEIEKLSSALKV 119
Query: 130 LRGVKFAKLTKASS 143
L GVK L+ +S+
Sbjct: 120 LVGVKHLDLSLSSA 133
>ref|NP_578051.1| (NC_003413) hypothetical protein [Pyrococcus furiosus DSM 3638]
gb|AAL80446.1| (AE010157) hypothetical protein [Pyrococcus furiosus DSM 3638]
Length = 138
Score = 105 bits (261), Expect = 2e-22
Identities = 46/134 (34%), Positives = 85/134 (63%), Gaps = 3/134 (2%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
I+RF VS+ + LL++ D I + GY++RSE +RD+IR+ +V W DE +
Sbjct: 3 IVRFGVSIPKELLEKFDGIIEEMGYTNRSEAIRDLIRDMVVRHEW---QLGDEEVAGTIT 59
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
++Y+H + ++ + ++D+QH ++ + H+HMDEHNCLE I+++G + +I+++ +
Sbjct: 60 IVYNHDEADVVRELLDLQHEYLNEIVSSLHVHMDEHNCLEVIVVKGRAKKIKKIADRLLS 119
Query: 130 LRGVKFAKLTKASS 143
L+GVK KL ++
Sbjct: 120 LKGVKHGKLVMTTT 133
>ref|NP_127117.1| (NC_000868) hypothetical protein [Pyrococcus abyssi]
sp|Q9UYR5|NIKR_PYRAB Putative nickel responsive regulator
pir||F75056 hypothetical protein PAB0960 - Pyrococcus abyssi (strain Orsay)
emb|CAB50347.1| (AJ248287) hypothetical protein [Pyrococcus abyssi]
Length = 138
Score = 104 bits (259), Expect = 3e-22
Identities = 46/134 (34%), Positives = 82/134 (60%), Gaps = 3/134 (2%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
++RFS+S+ LL++ D I + GY +RSE +RD+IR+ ++ W N E +
Sbjct: 3 LVRFSISIPAELLEKFDRIIEEIGYENRSEAIRDLIRDFIIRREWEVGN---EEVAGTIT 59
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
++Y+H + ++ + ++D+QH ++ T H+HMDEHNCLE I+++G + I+ + +
Sbjct: 60 IVYNHDEGDVVKELLDLQHEYLDEIISTLHVHMDEHNCLEVIVVKGKAKRIKMIASRLMS 119
Query: 130 LRGVKFAKLTKASS 143
L+GVK KL S+
Sbjct: 120 LKGVKHGKLVMTST 133
>ref|NP_618943.1| (NC_003552) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
gb|AAM07423.1| (AE011119) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
Length = 140
Score = 103 bits (257), Expect = 5e-22
Identities = 57/139 (41%), Positives = 78/139 (56%), Gaps = 2/139 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+ ++R VSL LL + D I K GYSSRSE +RD IR + W D ++
Sbjct: 2 ETELMRIGVSLPDTLLSKFDEIIEKRGYSSRSEGIRDAIRSYISYYEWMGDIKGH--RVG 59
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
+ VIYDH +R L+ + DIQH + + HIH+D NC E I+L G+ EI+ L
Sbjct: 60 TVAVIYDHTKRGLSNALADIQHHYSHLIKSSVHIHLDHDNCFEVIVLDGDGEEIKELAEA 119
Query: 127 IGGLRGVKFAKLTKASSFE 145
I L+GVKF+KLT +S E
Sbjct: 120 IMALKGVKFSKLTTVASNE 138
>ref|NP_142565.1| (NC_000961) hypothetical protein [Pyrococcus horikoshii]
sp|O58316|NIKR_PYRHO Putative nickel responsive regulator
pir||E71175 hypothetical protein PH0601 - Pyrococcus horikoshii
dbj|BAA29690.1| (AP000002) 138aa long hypothetical protein [Pyrococcus horikoshii]
Length = 138
Score = 103 bits (256), Expect = 7e-22
Identities = 46/134 (34%), Positives = 84/134 (62%), Gaps = 3/134 (2%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
+IRFS+S+ LL++ D I + GY +RSE +RD+IR+ ++ W N E +
Sbjct: 3 LIRFSISIPSKLLEKFDQIIEEIGYENRSEAIRDLIRDFIIRHEWEVGN---EEVAGTIT 59
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
++Y+H + ++ + ++D+QH ++ + H+HMDEHNCLE I+++G + +I+ + ++
Sbjct: 60 IVYNHDEGDVVKALLDLQHEYLDEIISSLHVHMDEHNCLEVIVVKGEAKKIKMIADKLLS 119
Query: 130 LRGVKFAKLTKASS 143
L+GVK KL S+
Sbjct: 120 LKGVKHGKLVMTST 133
>ref|NP_632866.1| (NC_003901) conserved protein [Methanosarcina mazei Goe1]
gb|AAM30538.1| (AE013309) conserved protein [Methanosarcina mazei Goe1]
Length = 167
Score = 103 bits (256), Expect = 7e-22
Identities = 56/139 (40%), Positives = 78/139 (55%), Gaps = 2/139 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+ ++R VSL LL + D I K GYSSRSE +RD IR + W D ++
Sbjct: 29 ETELMRIGVSLPDTLLSKFDEIIEKRGYSSRSEGIRDAIRSYISYYEWMGDIKGH--RVG 86
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
+ VIYDH +R L+ + DIQH + + HIH+D NC E ++L G+ EI+ L
Sbjct: 87 TVAVIYDHTKRGLSNALADIQHHYSHLIKSSVHIHLDHDNCFEVVVLDGDGEEIKELAEA 146
Query: 127 IGGLRGVKFAKLTKASSFE 145
I L+GVKF+KLT +S E
Sbjct: 147 IMSLKGVKFSKLTTVASNE 165
>ref|NP_616331.1| (NC_003552) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
gb|AAM04811.1| (AE010809) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
Length = 148
Score = 95.5 bits (236), Expect = 1e-19
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 2/139 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+ ++R +SL LL E D I K GYSSRSE +RD IR + W D ++
Sbjct: 10 ETELMRIGISLPDILLGEFDEIIGKRGYSSRSEGIRDAIRSYISYYEWMNDIKGH--RVG 67
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
+ +YDH +R L+ + DIQH + + H+H+D C E ++L G+ EI L
Sbjct: 68 TIAFVYDHTKRGLSNSLTDIQHHYSHLIKSSIHVHLDHKECFEVVVLNGDGKEIAELSET 127
Query: 127 IGGLRGVKFAKLTKASSFE 145
+ L+GVKF+KLT +S E
Sbjct: 128 MMVLKGVKFSKLTTVASNE 146
>ref|NP_632690.1| (NC_003901) putative nickel-responsive regulator NikR
[Methanosarcina mazei Goe1]
gb|AAM30362.1| (AE013291) putative nickel-responsive regulator NikR
[Methanosarcina mazei Goe1]
Length = 146
Score = 95.1 bits (235), Expect = 2e-19
Identities = 53/142 (37%), Positives = 76/142 (53%), Gaps = 2/142 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+ ++R VSL LL + D I K GYSSRSE +RD IR + + W + +
Sbjct: 2 ETELMRIGVSLPDTLLGKFDEIIEKRGYSSRSEAIRDSIRSYISYNEWMGNIKGHH--VG 59
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
+V+IYDH QR L+ + DIQH + + HI+ D +C E ++L+G EI L
Sbjct: 60 TIVIIYDHTQRGLSNVLTDIQHHYSHLIRSSIHIYPDREDCFEIVVLEGEGKEITELAEA 119
Query: 127 IGGLRGVKFAKLTKASSFEYNE 148
I L+GVK +KL S E +E
Sbjct: 120 IMALKGVKLSKLITTESNETDE 141
>ref|NP_247528.1| (NC_000909) conserved hypothetical protein [Methanococcus
jannaschii] [Methanocaldococcus jannaschii]
sp|Q57969|NIKR_METJA Putative nickel responsive regulator
pir||E64368 hypothetical protein homolog MJ0549 - Methanococcus jannaschii
gb|AAB98541.1| (U67504) conserved hypothetical protein [Methanococcus jannaschii]
[Methanocaldococcus jannaschii]
Length = 141
Score = 95.1 bits (235), Expect = 2e-19
Identities = 46/128 (35%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R S+SL LL E D I + GY+SRSE +RD IR+ +++ W + + + VI
Sbjct: 6 RISISLPSKLLREFDEIIAERGYASRSEAIRDAIRDYIIKHKWIHSLEGERA--GSISVI 63
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
Y+HH ++ +++ +IQH ++ T H+H+D +CLETI+++G++ I+ L + L+
Sbjct: 64 YNHHASDVMEKITEIQHNYTDIIVATLHLHLDHDHCLETILVRGDAKRIRELTDRLTALK 123
Query: 132 GVKFAKLT 139
GVK KL+
Sbjct: 124 GVKQVKLS 131
>ref|NP_275882.1| (NC_000916) conserved protein [Methanothermobacter
thermautotrophicus] [Methanothermobacter
thermautotrophicus str. Delta H]
sp|O26834|NIK2_METTH Putative nickel responsive regulator 2
pir||G69198 conserved hypothetical protein MTH739 - Methanobacterium
thermoautotrophicum (strain Delta H)
gb|AAB85243.1| (AE000853) conserved protein [Methanothermobacter
thermautotrophicus str. Delta H]
Length = 140
Score = 94.4 bits (233), Expect = 3e-19
Identities = 46/134 (34%), Positives = 81/134 (60%), Gaps = 2/134 (1%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
++R S+SL + LL+E D + GY SRS+ +RD +++ +V W N + +I ++
Sbjct: 1 MMRISMSLPKKLLNEFDEVLRDRGYQSRSKGIRDALKDYIVRYQWM--NEMEGERIGIIA 58
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
VIYDHH + + + DIQH ++ H+HM E +CLE I+++G+ +I+ L ++
Sbjct: 59 VIYDHHYTGVMEDLADIQHDYREYINAVMHVHMTERHCLEVIVVKGDVAKIRELTEKMMR 118
Query: 130 LRGVKFAKLTKASS 143
L+GV+ +LT S+
Sbjct: 119 LKGVEHVRLTSTST 132
>ref|NP_614785.1| (NC_003551) Predicted transcriptional regulator containing the
CopG/Arc/MetJ DNA-binding domain and a 3H domain
[Methanopyrus kandleri AV19]
gb|AAM02715.1| (AE010440) Predicted transcriptional regulator containing the
CopG/Arc/MetJ DNA-binding domain and a 3H domain
[Methanopyrus kandleri AV19]
Length = 141
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/137 (34%), Positives = 75/137 (54%), Gaps = 3/137 (2%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+D+++R S+++ + LL +++ I ++SRSE+ R +RE L W E DE
Sbjct: 5 EDNLVRTSITVPEQLLQKVNELIASGYFASRSEIFRQALREYLQRIEWTE-RVGDEEYFG 63
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
L ++ H + E ++ +QH ++ TTHIH+ CLE ++LQG I L
Sbjct: 64 ALTYVFQHERAE--PELVKVQHEFTDVIISTTHIHVSPEKCLEVLLLQGPGKRIAELAKR 121
Query: 127 IGGLRGVKFAKLTKASS 143
I G+RGV+ AKLT SS
Sbjct: 122 IRGVRGVEQAKLTVVSS 138
>ref|NP_616689.1| (NC_003552) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
gb|AAM05169.1| (AE010854) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
Length = 145
Score = 84.3 bits (207), Expect = 3e-16
Identities = 47/139 (33%), Positives = 72/139 (50%), Gaps = 2/139 (1%)
Query: 1 MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPN 60
M + ++R VS+ LL + D I K SRSE +RD + + W ED
Sbjct: 1 MSGDTMEAGLMRIGVSIPDALLTQFDEIIKKRDSPSRSEAIRDALISYITYYEWMEDIKG 60
Query: 61 DESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEI 120
++ + VIYDH + L+ +I++QH + + H+++D +C E I+L GN EI
Sbjct: 61 --RRVGTIAVIYDHKKSGLSNSIINVQHHYSHLIKYSVHMYLDTDDCFELIVLDGNGQEI 118
Query: 121 QRLQLEIGGLRGVKFAKLT 139
L I L+GVKF+KLT
Sbjct: 119 TELAGSIIALKGVKFSKLT 137
>ref|NP_617713.1| (NC_003552) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
gb|AAM06193.1| (AE010981) transcriptional regulator, CopG family [Methanosarcina
acetivorans str. C2A] [Methanosarcina acetivorans C2A]
Length = 140
Score = 83.2 bits (204), Expect = 7e-16
Identities = 46/133 (34%), Positives = 73/133 (54%), Gaps = 2/133 (1%)
Query: 7 DDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIA 66
+ ++R VSL LLD+ D ++K GYSSRSE +RD IR W + ++ A
Sbjct: 2 EKKLMRIGVSLPGELLDKFDKTLMKRGYSSRSEGIRDAIRTYNQHYEWMQQIKG--ARAA 59
Query: 67 VLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLE 126
+ ++YD ++ + + IQH + + H H++E C ETIIL+G +I L +
Sbjct: 60 TISLVYDCSKKGITSTLAKIQHEYIDLITSSVHFHIEEDFCFETIILEGEGEKIVELAEK 119
Query: 127 IGGLRGVKFAKLT 139
I L+GVK ++LT
Sbjct: 120 ILSLKGVKHSRLT 132
>ref|NP_634681.1| (NC_003901) transcriptional regulator [Methanosarcina mazei Goe1]
gb|AAM32353.1| (AE013512) transcriptional regulator [Methanosarcina mazei Goe1]
Length = 140
Score = 81.6 bits (200), Expect = 2e-15
Identities = 45/130 (34%), Positives = 69/130 (52%), Gaps = 2/130 (1%)
Query: 10 IIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLV 69
++R +SL LLD+ D ++K GYSSRSE +RD IR W + S A +
Sbjct: 5 LMRIGISLPGELLDKFDKTLMKRGYSSRSEGIRDAIRTYNQHYEWMKQIRGSRS--ATIS 62
Query: 70 VIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGG 129
++YD ++ + + +IQH + + H HM+E C E IIL+G +I L I
Sbjct: 63 IVYDCSKKGVTSTLAEIQHEYVDMISSSVHFHMEEDLCFEVIILRGEGEQIVDLAQRILS 122
Query: 130 LRGVKFAKLT 139
++GVK +LT
Sbjct: 123 IKGVKHLRLT 132
>ref|NP_458337.1| (NC_003198) nickel responsive regulator [Salmonella enterica subsp.
enterica serovar Typhi]
ref|NP_462485.1| (NC_003197) nickel-responsive transcriptional regulator [Salmonella
typhimurium LT2]
sp|Q8XEK6|NIKR_SALTY Nickel responsive regulator
gb|AAL22444.1| (AE008865) nickel-responsive transcriptional regulator [Salmonella
typhimurium LT2]
emb|CAD08046.1| (AL627281) nickel responsive regulator [Salmonella enterica subsp.
enterica serovar Typhi]
Length = 133
Score = 78.6 bits (192), Expect = 2e-14
Identities = 39/127 (30%), Positives = 72/127 (55%), Gaps = 3/127 (2%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R +++L +LL+ LD+ + GY++RSE +RD++R L ++ E AVL +
Sbjct: 3 RVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEATQEHGTQG---FAVLSYV 59
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
Y+H +R+L R++ QH + T H+H++ +CLE +L+G+ ++Q ++ R
Sbjct: 60 YEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQR 119
Query: 132 GVKFAKL 138
GV+ L
Sbjct: 120 GVRHGHL 126
>ref|NP_290047.1| (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
ref|NP_312375.1| (NC_002695) nickel-responsive regulatory protein [Escherichia coli
O157:H7]
ref|NP_417938.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
sp|P28910|NIKR_ECOLI Nickel responsive regulator
pir||S47700 hypothetical 15.1K protein (nike-rhsb intergenic region) -
Escherichia coli
gb|AAC61882.1| (L02370) unknown [Escherichia coli]
gb|AAB18456.1| (U00039) alternate gene name yhhG [Escherichia coli]
gb|AAC76506.1| (AE000423) orf, hypothetical protein [Escherichia coli K12]
emb|CAA70150.1| (Y08952) nickel responsive regulator [Escherichia coli]
gb|AAG58608.1|AE005572_6 (AE005572) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
dbj|BAB37771.1| (AP002565) nickel-responsive regulatory protein [Escherichia coli
O157:H7]
Length = 133
Score = 78.2 bits (191), Expect = 2e-14
Identities = 38/127 (29%), Positives = 72/127 (55%), Gaps = 3/127 (2%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R +++L +LL+ LD+ + GY++RSE +RD++R L ++ + AVL +
Sbjct: 3 RVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQG---FAVLSYV 59
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
Y+H +R+L R++ QH + T H+H++ +CLE +L+G+ ++Q ++ R
Sbjct: 60 YEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQR 119
Query: 132 GVKFAKL 138
GV+ L
Sbjct: 120 GVRHGHL 126
>ref|NP_342174.1| (NC_002754) Conserved hypothetical protein [Sulfolobus
solfataricus]
sp|Q9UX49|NIKR_SULSO Putative nickel responsive regulator
emb|CAB57643.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
gb|AAK40964.1| (AE006693) Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 133
Score = 67.8 bits (164), Expect = 3e-11
Identities = 37/134 (27%), Positives = 73/134 (53%), Gaps = 7/134 (5%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
+ S+SL + L EL++ II+ G RS++ + +R L E+ +E ++ ++
Sbjct: 5 KISISLPKELYRELEDFIIRKGIPDRSKIFQIALRNYL-----DENRDGNEIIYGIINLV 59
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
YDH E ++ + +IQH ++ T H+H+ E C+E I ++G ++ L ++G +R
Sbjct: 60 YDHE--EASEALTEIQHEYNDSIISTLHLHVSEKICIEAIAVKGEKRKLVELNNKLGQIR 117
Query: 132 GVKFAKLTKASSFE 145
G+ A+L + +E
Sbjct: 118 GILKARLLISFPYE 131
>sp|Q9AL83|NIKR_BRUSU Nickel responsive regulator
emb|CAC24692.1| (AJ278644) putative NikR protein [Brucella melitensis biovar Suis]
Length = 132
Score = 66.2 bits (160), Expect = 9e-11
Identities = 36/127 (28%), Positives = 65/127 (50%), Gaps = 2/127 (1%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R ++++ +L+ LD I GY +RSE +RD+ R L + + E E+ + VL
Sbjct: 3 RITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQM--EACVGVLSYT 60
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
YDH R+L++++ + H + + H+H+D CLE IL+G + +++ + R
Sbjct: 61 YDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKGKTDDVRHFADHVKAER 120
Query: 132 GVKFAKL 138
V L
Sbjct: 121 HVTHGTL 127
>ref|NP_541464.1| (NC_003318) Nickel-responsive regulator NikR [Brucella melitensis]
gb|AAL53728.1| (AE009684) Nickel-responsive regulator NikR [Brucella melitensis]
Length = 151
Score = 63.9 bits (154), Expect = 5e-10
Identities = 35/127 (27%), Positives = 64/127 (49%), Gaps = 2/127 (1%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R ++++ +L+ LD I GY +RSE +RD+ R L + + E E+ + VL
Sbjct: 22 RITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQM--EACVGVLSYT 79
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
YDH R+L++++ + H + + H+H+D CLE IL+ + +++ + R
Sbjct: 80 YDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKSKTDDVRHFADHVKAER 139
Query: 132 GVKFAKL 138
V L
Sbjct: 140 HVTHGTL 146
>sp|Q8YCP2|NIKR_BRUME Nickel responsive regulator
Length = 132
Score = 63.9 bits (154), Expect = 5e-10
Identities = 35/127 (27%), Positives = 64/127 (49%), Gaps = 2/127 (1%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVI 71
R ++++ +L+ LD I GY +RSE +RD+ R L + + E E+ + VL
Sbjct: 3 RITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQM--EACVGVLSYT 60
Query: 72 YDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLR 131
YDH R+L++++ + H + + H+H+D CLE IL+ + +++ + R
Sbjct: 61 YDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKSKTDDVRHFADHVKAER 120
Query: 132 GVKFAKL 138
V L
Sbjct: 121 HVTHGTL 127
>ref|NP_279286.1| (NC_002607) Vng0147c [Halobacterium sp. NRC-1]
gb|AAG18766.1| (AE004981) Vng0147c [Halobacterium sp. NRC-1]
Length = 155
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 5/121 (4%)
Query: 14 SVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYD 73
SVS+ + LL+ LD+ +GY+ RSE+VR+ R L E + + + V+ V++D
Sbjct: 18 SVSMPEELLERLDDFADDHGYTGRSEVVREASRNLLGE--FEDKKLEGRELMGVVTVVFD 75
Query: 74 HHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGV 133
+ + ++M+ ++H V H H+ H+C+E +L+G+ ++ + +G +R
Sbjct: 76 YETTTVEEKMMHLRHEHEGLVASNFHSHVGGHHCMELFVLEGS---LESISTFVGKIRAT 132
Query: 134 K 134
K
Sbjct: 133 K 133
>sp|Q9HSN7|NIKR_HALN1 Putative nickel responsive regulator
Length = 142
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 5/121 (4%)
Query: 14 SVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYD 73
SVS+ + LL+ LD+ +GY+ RSE+VR+ R L E + + + V+ V++D
Sbjct: 5 SVSMPEELLERLDDFADDHGYTGRSEVVREASRNLLGE--FEDKKLEGRELMGVVTVVFD 62
Query: 74 HHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGV 133
+ + ++M+ ++H V H H+ H+C+E +L+G+ ++ + +G +R
Sbjct: 63 YETTTVEEKMMHLRHEHEGLVASNFHSHVGGHHCMELFVLEGS---LESISTFVGKIRAT 119
Query: 134 K 134
K
Sbjct: 120 K 120
>ref|NP_247752.1| (NC_000909) conserved hypothetical protein [Methanococcus
jannaschii] [Methanocaldococcus jannaschii]
sp|Q58177|Y767_METJA Hypothetical protein MJ0767
pir||G64395 hypothetical protein MJ0767 - Methanococcus jannaschii
gb|AAB98762.1| (U67522) conserved hypothetical protein [Methanococcus jannaschii]
[Methanocaldococcus jannaschii]
Length = 135
Score = 57.0 bits (136), Expect = 6e-08
Identities = 37/133 (27%), Positives = 72/133 (53%), Gaps = 6/133 (4%)
Query: 9 SIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVL 68
++ R S+S + LL E+D + K GYSSRSEL+RD +R+ ++E+N N E+ ++
Sbjct: 3 NVERISISFPKFLLKEIDEVVKKKGYSSRSELIRDAVRKYVLENNPLNKN---ETVSGII 59
Query: 69 VVIYDHHQRELNQ-RMIDIQHASGTHVLCTTHI--HMDEHNCLETIILQGNSFEIQRLQL 125
+V+Y+ + L + + +H L ++ ++ +E +++GNS +I +
Sbjct: 60 IVVYNPTKEALEKMSKLYFEHNKVIKSLNQAYVTTSCGKNAKVEIFVVEGNSKDISKFYE 119
Query: 126 EIGGLRGVKFAKL 138
EI + G + K+
Sbjct: 120 EIEKINGKIYDKV 132
>ref|NP_275746.1| (NC_000916) conserved protein [Methanothermobacter
thermautotrophicus] [Methanothermobacter
thermautotrophicus str. Delta H]
sp|O26703|NIK1_METTH Putative nickel responsive regulator 1
pir||B69180 conserved hypothetical protein MTH603 - Methanobacterium
thermoautotrophicum (strain Delta H)
gb|AAB85109.1| (AE000842) conserved protein [Methanothermobacter
thermautotrophicus str. Delta H]
Length = 127
Score = 50.1 bits (118), Expect = 7e-06
Identities = 38/124 (30%), Positives = 63/124 (50%), Gaps = 8/124 (6%)
Query: 14 SVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYD 73
SVSL + LL+E+D + G+S RS+++R R L+++ N E AVL +I
Sbjct: 5 SVSLGEKLLEEIDALRDELGFSGRSDVIRVAAR-MLIDEKRNLHELNGEIN-AVLFLI-- 60
Query: 74 HHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQ---LEIGGL 130
H R + + I+H + H H+ + NCLE I++G S ++ L L G +
Sbjct: 61 -HPRRVEDLVTKIKHDYEDIIGTQLHSHLKDGNCLELFIIEGESMRVRELAERFLACGKM 119
Query: 131 RGVK 134
+ +K
Sbjct: 120 KHIK 123
>ref|NP_377483.1| (NC_003106) 127aa long conserved hypothetical protein [Sulfolobus
tokodaii]
dbj|BAB66592.1| (AP000986) 127aa long conserved hypothetical protein [Sulfolobus
tokodaii]
Length = 127
Score = 43.5 bits (101), Expect = 6e-04
Identities = 26/124 (20%), Positives = 63/124 (49%), Gaps = 12/124 (9%)
Query: 12 RFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKI-AVLVV 70
+ S+S+ + L + L+ + + RS++ + IR N+ ++N + ++ + ++ +
Sbjct: 4 KISISIPRELYERLERYLKEKQIVDRSKIFQIAIR------NFLDENESSDTFVYGIINL 57
Query: 71 IYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGL 130
+YD E+ + QH ++ HIH+ + C+E + ++G ++ L ++ L
Sbjct: 58 VYDEDASEVTK----FQHEHEDKIISVMHIHVG-NECIEALAVKGKKRDLVELTAKLSQL 112
Query: 131 RGVK 134
+GVK
Sbjct: 113 KGVK 116
>ref|NP_420633.1| (NC_002696) conserved hypothetical protein [Caulobacter crescentus
CB15]
gb|AAK23801.1| (AE005857) conserved hypothetical protein [Caulobacter crescentus
CB15]
Length = 134
Score = 40.0 bits (92), Expect = 0.007
Identities = 23/115 (20%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 29 IIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYDHHQRELNQRMIDIQH 88
+ + G SRS+++ ++IR +L E + D + +IY + + Q
Sbjct: 2 VAERGLPSRSQMIAELIRHELAEHSGERP---DAMLAGTITLIYRAESGRVRHALAQTQL 58
Query: 89 ASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGVKFAKLTKASS 143
V+ ++ +++ +E +++QG + +Q+L + +RGV+ KL ++
Sbjct: 59 GYVKEVISAQNVFLEDDQAMEVLLVQGPAERLQQLCDALRKVRGVQQIKLVTTTA 113
Database: /home/scwang/download_20020708_db/nr
Posted date: Aug 7, 2002 12:55 PM
Number of letters in database: 324,149,939
Number of sequences in database: 1,026,957
Lambda K H
0.318 0.135 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,803,782
Number of Sequences: 1026957
Number of extensions: 3296549
Number of successful extensions: 8618
Number of sequences better than 1.0e-02: 30
Number of HSP's better than 0.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 8567
Number of HSP's gapped (non-prelim): 30
length of query: 148
length of database: 324,149,939
effective HSP length: 110
effective length of query: 38
effective length of database: 211,184,669
effective search space: 8025017422
effective search space used: 8025017422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 91 (39.7 bits)