BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15646011|ref|NP_208192.1| conserved hypothetical
protein [Helicobacter pylori 26695]
         (235 letters)

Database: /home/scwang/download_20020708_db/nr
           1,026,957 sequences; 324,149,939 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_208192.1|  (NC_000915) conserved hypothetical protein...   479  e-135
ref|NP_224143.1|  (NC_000921) putative [Helicobacter pylori ...   450  e-126
ref|NP_634315.1|  (NC_003901) Zinc metalloprotease [Methanos...   174  7e-43
ref|NP_346969.1|  (NC_003030) Predicted metal-dependent hydr...    98  7e-20
ref|NP_634625.1|  (NC_003901) Zinc metalloprotease [Methanos...    95  7e-19
ref|NP_638254.1|  (NC_003902) conserved hypothetical protein...    85  6e-16
ref|NP_618386.1|  (NC_003552) conserved hypothetical protein...    85  8e-16
gb|AAM08233.1|  (AF410854) unknown [Legionella pneumophila]        82  5e-15
ref|NP_070535.1|  (NC_000917) hypothetical protein [Archaeog...    77  2e-13
ref|NP_279256.1|  (NC_002607) Vng0110c [Halobacterium sp. NR...    69  6e-11
ref|NP_561719.1|  (NC_003366) hypothetical protein [Clostrid...    67  1e-10
ref|NP_603843.1|  (NC_003454) Zinc metalloprotease [Fusobact...    66  3e-10
ref|NP_281803.1|  (NC_002163) hypothetical protein Cj0620 [C...    64  1e-09
ref|NP_326157.1|  (NC_002771) conserved hypothetical protein...    61  9e-09
ref|NP_276076.1|  (NC_000916) unknown [Methanothermobacter t...    60  3e-08
ref|NP_360041.1|  (NC_003103) unknown [Rickettsia conorii] >...    59  4e-08
ref|NP_654268.1|  (NC_003995) DUF45, Protein of unknown func...    59  4e-08
ref|NP_578408.1|  (NC_003413) hypothetical protein [Pyrococc...    58  1e-07
gb|AAD24685.1|AF083877_5  (AF083877) unknown [Erwinia amylov...    57  1e-07
ref|NP_617886.1|  (NC_003552) conserved hypothetical protein...    57  2e-07
gb|AAM46140.1|AF380136_1  (AF380136) metalloprotease [Helico...    55  6e-07
ref|NP_207599.1|  (NC_000915) hypothetical protein [Helicoba...    55  6e-07
ref|NP_297587.1|  (NC_002488) hypothetical protein [Xylella ...    54  1e-06
ref|NP_142658.1|  (NC_000961) hypothetical protein [Pyrococc...    54  1e-06
ref|NP_223460.1|  (NC_000921) putative [Helicobacter pylori ...    52  5e-06
ref|NP_540932.1|  (NC_003317) zinc metallopeptidases [Brucel...    52  7e-06
ref|NP_127009.1|  (NC_000868) hypothetical protein [Pyrococc...    50  3e-05
ref|NP_105795.1|  (NC_002678) hypothetical protein [Mesorhiz...    49  6e-05
ref|NP_541426.1|  (NC_003318) zinc metallopeptidases [Brucel...    49  6e-05
ref|NP_384132.1|  (NC_003047) CONSERVED HYPOTHETICAL PROTEIN...    49  6e-05
ref|NP_518642.1|  (NC_003295) HYPOTHETICAL PROTEIN [Ralstoni...    48  8e-05
ref|NP_275026.1|  (NC_003112) conserved hypothetical protein...    45  5e-04
ref|NP_078157.1|  (NC_002162) conserved hypothetical [Ureapl...    45  5e-04
ref|NP_661599.1|  (NC_002932) zinc protease, putative [Chlor...    43  0.003
ref|NP_629342.1|  (NC_003888) hypothetical protein [Streptom...    43  0.003
sp|O42287|ITN1_XENLA  Intersectin 1 >gi|7512152|pir||T09194 ...    42  0.004
ref|NP_283232.1|  (NC_003116) hypothetical protein NMA0403 [...    42  0.006
gb|AAD24686.1|AF083877_6  (AF083877) unknown [Erwinia amylov...    42  0.006
ref|NP_273283.1|  (NC_003112) conserved hypothetical protein...    42  0.006
ref|NP_282887.1|  (NC_003116) hypothetical protein NMA0032 [...    42  0.006
gb|AAD38302.1|AF036242_2  (AF036242) unknown [Neisseria meni...    41  0.010
ref|NP_353056.1|  (NC_003062) AGR_C_25p [Agrobacterium tumef...    41  0.010
>ref|NP_208192.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
           26695]
 pir||A64695 conserved hypothetical protein HP1401 - Helicobacter pylori
           (strain 26695)
 gb|AAD08444.1| (AE000640) conserved hypothetical protein [Helicobacter pylori
           26695]
          Length = 235

 Score =  479 bits (1234), Expect = e-135
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MNAYCLTLNDTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKE 60
           MNAYCLTLNDTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKE
Sbjct: 1   MNAYCLTLNDTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKE 60

Query: 61  QQQNFLNQNRQSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLE 120
           QQQNFLNQNRQSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLE
Sbjct: 61  QQQNFLNQNRQSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLE 120

Query: 121 NRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLE 180
           NRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLE
Sbjct: 121 NRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLE 180

Query: 181 LAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYLERS 235
           LAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYLERS
Sbjct: 181 LAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYLERS 235
>ref|NP_224143.1| (NC_000921) putative [Helicobacter pylori J99]
 pir||D71808 hypothetical protein jhp1425 - Helicobacter pylori (strain J99)
 gb|AAD07006.1| (AE001565) putative [Helicobacter pylori J99]
          Length = 235

 Score =  450 bits (1158), Expect = e-126
 Identities = 223/235 (94%), Positives = 227/235 (95%)

Query: 1   MNAYCLTLNDTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKE 60
           MNAYCLTLN+TNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRL WIKE
Sbjct: 1   MNAYCLTLNNTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLPWIKE 60

Query: 61  QQQNFLNQNRQSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLE 120
           QQQNFLNQNRQSQR MLERESHYLFGKRYLLKIEHT KKHFVLQ+PK LILHVHQKTSLE
Sbjct: 61  QQQNFLNQNRQSQREMLERESHYLFGKRYLLKIEHTIKKHFVLQSPKCLILHVHQKTSLE 120

Query: 121 NRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLE 180
           NRLKVLENYYRQVLREKIQT IN+YEKILNESIQSFKIQKMKRIWGSCNIAKR LLFNLE
Sbjct: 121 NRLKVLENYYRQVLREKIQTYINQYEKILNESIQSFKIQKMKRIWGSCNIAKRTLLFNLE 180

Query: 181 LAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYLERS 235
           LAK PRKGIEYVVVHELLHLK RHHNEYFRDLLSLYLP+WQRAKASLKETYLERS
Sbjct: 181 LAKAPRKGIEYVVVHELLHLKARHHNEYFRDLLSLYLPDWQRAKASLKETYLERS 235
>ref|NP_634315.1| (NC_003901) Zinc metalloprotease [Methanosarcina mazei Goe1]
 gb|AAM31987.1| (AE013471) Zinc metalloprotease [Methanosarcina mazei Goe1]
          Length = 238

 Score =  174 bits (441), Expect = 7e-43
 Identities = 83/224 (37%), Positives = 135/224 (60%)

Query: 6   LTLNDTNIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNF 65
           + L D  + +  KDIK++H+SV PP+G V +S PL ++ +++R+  I RL WIK+Q++ F
Sbjct: 5   IELGDITVDVVLKDIKNIHLSVYPPNGRVKISAPLRMDIDTIRVFAISRLGWIKQQRKKF 64

Query: 66  LNQNRQSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKV 125
             Q R++ R  L+ ESHY++GKRYLLK+    +   V      +IL V   T  + R  +
Sbjct: 65  QEQERETPREYLDLESHYVWGKRYLLKVIEVNEAPSVELKHSKMILRVRPGTDDKKRQSI 124

Query: 126 LENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVP 185
           ++ +YR+ L++ I   I R+E +L   ++ F +Q+M+  WGSCN   R +  N ELAK P
Sbjct: 125 IDAWYREQLKKAIPPLIARWEPLLGVKVERFFVQRMRTKWGSCNHKARNIRLNTELAKKP 184

Query: 186 RKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
            + +EY +VHE+ H+    HN +F  L+  ++P WQ  +  L +
Sbjct: 185 EECLEYTIVHEMAHILEPTHNSHFITLMDQFMPKWQFCRDRLNQ 228
>ref|NP_346969.1| (NC_003030) Predicted metal-dependent hydrolase [Clostridium
           acetobutylicum]
 gb|AAK78309.1|AE007547_6 (AE007547) Predicted metal-dependent hydrolase [Clostridium
           acetobutylicum]
          Length = 259

 Score = 98.2 bits (243), Expect = 7e-20
 Identities = 58/220 (26%), Positives = 119/220 (53%), Gaps = 10/220 (4%)

Query: 14  AIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQ---QNFLNQNR 70
           ++ +K+ K + ISV   D ++ V  P  + +E ++  + K++ WI +Q    +N ++ N 
Sbjct: 38  SLVRKERKSIKISV-NRDFTIEVIAPFNVAEEEIKNVVYKKMKWIIKQMKRMENIIDINE 96

Query: 71  QSQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYY 130
           + +    + ++ Y+FG  Y L ++   K    +     + +++ +K + E +    E +Y
Sbjct: 97  EIKYS--DGDAFYIFGTPYRLIVKKGIKNKMRIFGEN-VYMYIKEKDNYEYKKNYAEKWY 153

Query: 131 RQVLREKIQTCINRYEKILNESIQS---FKIQKMKRIWGSCNIAKRALLFNLELAKVPRK 187
           +++   +++   N   KI +E         I+KMK  WGS + A   ++ N +L K+P+ 
Sbjct: 154 KKIAAIELEYLYNEKYKIFDEIYDEKPKLCIRKMKSKWGSYSPADNKVVLNTQLVKIPKT 213

Query: 188 GIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASL 227
            IEYV++HEL H+K R+H + F + ++ ++P+W+  K SL
Sbjct: 214 CIEYVIIHELCHVKFRNHRKEFYNYVNNFMPDWKLKKESL 253
>ref|NP_634625.1| (NC_003901) Zinc metalloprotease [Methanosarcina mazei Goe1]
 gb|AAM32297.1| (AE013504) Zinc metalloprotease [Methanosarcina mazei Goe1]
          Length = 245

 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 61/210 (29%), Positives = 108/210 (51%), Gaps = 8/210 (3%)

Query: 27  VCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNF-LNQNRQSQRGMLERESHYLF 85
           V  PD SV    P  L+ E++R  + K+  W++E+   F +N+    ++   + E     
Sbjct: 30  VVRPDLSVEFRAPHGLSREAIREMVQKKAAWVQEKLDWFEVNRLPCQEKEYTDGEKFLYL 89

Query: 86  GKRYLLKI--EHTTKKHFVLQNPKYLILHVHQKTSLENR----LKVLENYYRQVLREKIQ 139
           GK Y L +      KK F   +   + + + +    E +     K + N+Y +   ++++
Sbjct: 90  GKEYPLTVLPVEGIKKAFASFSGSEITVLLPEPAPEELKPSLVKKAVWNFYSECAEKEVE 149

Query: 140 TCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLH 199
             +  Y +ILN  I +FK++  K+ WGSC+ A   L  N +L   P + +EYVVVHE+ H
Sbjct: 150 KFLKAYAEILNIDIPAFKVKHQKKRWGSCS-ADNVLRINFQLMMAPPEQLEYVVVHEICH 208

Query: 200 LKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           +K ++H+  F DL+   +P +Q  + SLK+
Sbjct: 209 VKEKNHSVKFWDLVGELMPGYQVHRKSLKK 238
>ref|NP_638254.1| (NC_003902) conserved hypothetical protein [Xanthomonas campestris
           pv. campestris str. ATCC 33913]
 gb|AAM42178.1| (AE012404) conserved hypothetical protein [Xanthomonas campestris
           pv. campestris str. ATCC 33913]
          Length = 248

 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 61/201 (30%), Positives = 94/201 (46%), Gaps = 5/201 (2%)

Query: 30  PDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQ-SQRGMLERESHYLFGKR 88
           PDG V +  PL   D  +R +L +R  WI         + R  + R  +  E+    G+R
Sbjct: 40  PDGCVRLDAPLQATDTQIRRALTRRARWIHLHLVEIEQRLRHVTPREYVSGETVLYLGRR 99

Query: 89  YLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEKI 148
           Y LK+    + H V     Y+   V  +     R   LE++ R+  R  I   +      
Sbjct: 100 YRLKVILDDQMHDVRLRCGYVEARVPSRAPEVVRA-ALEDWQRERARLLIPQRVANMAAQ 158

Query: 149 LN--ESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHN 206
           L   + +    ++ M+R WGSC+ + R  L NL L +VP   I+YV++HEL HLK  +H 
Sbjct: 159 LRWIKQMPPLSLRMMQRQWGSCSPSGRISL-NLGLIRVPGACIDYVILHELCHLKIHNHG 217

Query: 207 EYFRDLLSLYLPNWQRAKASL 227
           + F  LL  ++P W+  K  L
Sbjct: 218 KAFYRLLDAHMPGWREIKQRL 238
>ref|NP_618386.1| (NC_003552) conserved hypothetical protein [Methanosarcina
           acetivorans str. C2A] [Methanosarcina acetivorans C2A]
 gb|AAM06866.1| (AE011059) conserved hypothetical protein [Methanosarcina
           acetivorans str. C2A] [Methanosarcina acetivorans C2A]
          Length = 245

 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 61/210 (29%), Positives = 102/210 (48%), Gaps = 8/210 (3%)

Query: 27  VCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNF-LNQNRQSQRGMLERESHYLF 85
           V  PD  V    P  L+ E++R  L K+  W++E+   F  N+    ++   E E +   
Sbjct: 30  VVRPDLKVEFRAPHGLSLEAIRDMLQKKAGWVQEKLDWFEANRLPGQEKRYTEGEIYLYM 89

Query: 86  GKRYLLKI--EHTTKKHFVLQNPKYLILHVHQKTSLENR----LKVLENYYRQVLREKIQ 139
           G+ Y LKI      KK     N   L + + +    E R     K + ++YR+     ++
Sbjct: 90  GREYPLKILAGKGIKKPLASFNGAELTVLIPEAVPEELRPVLVKKAVWDFYRECAESNVE 149

Query: 140 TCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLH 199
             +  Y + L  +   FK++  KR WGSC+ A   +  N +L   P + +EYVVVHEL H
Sbjct: 150 RLLKIYSEKLKIAPPIFKVKYQKRRWGSCS-ADNVIRINFQLMMAPPEQLEYVVVHELCH 208

Query: 200 LKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           +K ++H+  F  L+   +P ++  + SLK+
Sbjct: 209 VKEKNHSFRFWKLVGGLMPGYEIHRKSLKK 238
>gb|AAM08233.1| (AF410854) unknown [Legionella pneumophila]
          Length = 243

 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 55/208 (26%), Positives = 102/208 (48%), Gaps = 19/208 (9%)

Query: 30  PDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQS-QRGMLERESHYLFGKR 88
           PD  V V  P +   + + +++ KR  W+  +   F +Q      R  +  ESHY  G++
Sbjct: 35  PDCQVIVFAPPSATHDEIIVAVNKRAKWVYNKLHIFRSQQEYIIPRQYISGESHYYLGRK 94

Query: 89  YLLKIEHTTKKHFVLQNPKYLI----LHVHQKTSLENRLKVLENYYRQVLREKIQTCINR 144
           Y+LK+   +K       P+  +    L +    ++E+R ++L  +Y+Q   +  +    R
Sbjct: 95  YVLKVIEDSKA-----KPQVKLVRGQLQIIAARNIEHRRQLLSEWYKQ---KAFEVFSKR 146

Query: 145 YEKILN-----ESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLH 199
            +++L+     +   +  ++ M+  WGSC +  +  L N  L K P   I+YV++HEL H
Sbjct: 147 LDQLLSTAPWIKERPTIHLRAMRSRWGSCAVNGKITL-NTHLIKAPTACIDYVILHELCH 205

Query: 200 LKTRHHNEYFRDLLSLYLPNWQRAKASL 227
               +H++ F  LL+   PNW++ K  L
Sbjct: 206 HSEHNHSDKFYRLLNQVSPNWKQVKQYL 233
>ref|NP_070535.1| (NC_000917) hypothetical protein [Archaeoglobus fulgidus]
 pir||B69463 hypothetical protein AF1707 - Archaeoglobus fulgidus
 gb|AAB89540.1| (AE000985) A. fulgidus predicted coding region AF1707
           [Archaeoglobus fulgidus]
          Length = 219

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 57/222 (25%), Positives = 110/222 (48%), Gaps = 20/222 (9%)

Query: 12  NIAIEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQ 71
           N+ +E+K+++++ I V   DG V V  P   + +S    + K   WIK++          
Sbjct: 2   NVVVERKNVRNVRIQVLA-DGKVRVVAPPDFDVDSF---ISKHADWIKKK---------- 47

Query: 72  SQRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLEN-RLKVLENYY 130
             R  +E  +  + GK  +L +    K + ++++  + I    +   ++   L+ L+   
Sbjct: 48  --RAEIESLAEEIKGKERMLLLNG--KFYHLVKDSGFEIKEGEEVGVVKYYSLRNLKRNL 103

Query: 131 RQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIE 190
             +LRE+++  ++ Y ++L  +     I+  K  W SC+ +K  L FNL    +P K  E
Sbjct: 104 ASILREELKRNVSFYSRLLGINYGRIFIKMQKTKWASCS-SKGNLSFNLASLALPEKLRE 162

Query: 191 YVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYL 232
           Y+VVHEL+HL    H+  F + +  Y P ++ A+  LK+ ++
Sbjct: 163 YIVVHELVHLLEPKHSRLFWETVGFYYPEYEEAERELKKYWI 204
>ref|NP_279256.1| (NC_002607) Vng0110c [Halobacterium sp. NRC-1]
 gb|AAG18736.1| (AE004978) Vng0110c [Halobacterium sp. NRC-1]
          Length = 241

 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 49/183 (26%), Positives = 87/183 (46%), Gaps = 8/183 (4%)

Query: 41  ALNDESLRLSLIKRLHWIKEQQQNFLNQNRQSQRGMLERESHYLF-GKRYLLKIEHTTKK 99
           A ++ES    L + L+W+ E ++ +     ++     E  + + + G  + + +E     
Sbjct: 45  AESEESPEALLSENLNWVLETKRTYERHRERAPERRFEPGAAFPYLGDDHEIVVE-PRPA 103

Query: 100 HFVLQNPKYLILHVHQKTSLENRLK-VLENYYRQVLREKIQTCINRYEKILNESIQSFKI 158
           H V        + + Q T  ++ LK VLEN+YR   RE +    +     +N +    ++
Sbjct: 104 HGVGDGE----IRLRQSTVDQSSLKRVLENFYRSRAREHLTDRTDALADSMNHTYDRIEL 159

Query: 159 QKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLP 218
           +  +  WGSC+     L FN  L   P   I+YVVVHEL HL+   HN+ F  L+ + +P
Sbjct: 160 RNQRTRWGSCS-TNGVLSFNWRLVMAPPDVIDYVVVHELAHLRESGHNDRFWRLVEMEIP 218

Query: 219 NWQ 221
            ++
Sbjct: 219 EYR 221
>ref|NP_561719.1| (NC_003366) hypothetical protein [Clostridium perfringens]
 dbj|BAB80509.1| (AP003188) hypothetical protein [Clostridium perfringens]
          Length = 125

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 36/110 (32%), Positives = 59/110 (52%), Gaps = 1/110 (0%)

Query: 120 ENRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNL 179
           E   K +E +YR+     I+  +  Y K      +S K+++ KR WGSC      LLFN 
Sbjct: 10  ERLRKAIELWYREEGVRIIKDRVEHYLKFYPVKPRSIKVKEQKRRWGSCTYYND-LLFNW 68

Query: 180 ELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
                P K ++Y+VVHE+ H+  + H++ + + +S  +PN++  K  LKE
Sbjct: 69  RCIMAPLKVVDYIVVHEMTHMVHKDHSKNYWNFVSKIIPNYKEQKMWLKE 118
>ref|NP_603843.1| (NC_003454) Zinc metalloprotease [Fusobacterium nucleatum subsp.
           nucleatum ATCC 25586]
 gb|AAL95142.1| (AE010602) Zinc metalloprotease [Fusobacterium nucleatum subsp.
           nucleatum ATCC 25586]
          Length = 229

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 51/217 (23%), Positives = 105/217 (47%), Gaps = 11/217 (5%)

Query: 15  IEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKE--QQQNFLNQNRQS 72
           + KK IK+  I + P D  + VS PL  +++ +   +  +  WI+   ++   + +N+ +
Sbjct: 18  VTKKKIKNFIIRIYP-DLRIAVSVPLLASNKDIENFVQNKKEWIETTLEKIKIVKENKNN 76

Query: 73  QRGMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQK-TSLENRLKVLENYYR 131
               L+     + GK    K+  +  +   L +     ++++ K T      K L  +  
Sbjct: 77  ----LKENVIKILGKEIEKKVIKSDLERIRLTDTS---IYIYSKDTGNAGIEKKLLEWKI 129

Query: 132 QVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEY 191
           + L+  +   +  Y K+LN +I  ++I+K+   WG  +  +  + FN +L +   + IEY
Sbjct: 130 EKLKAILDEYLANYTKLLNRNINYYQIKKLSSAWGIYHKKENYISFNFDLIEKDIECIEY 189

Query: 192 VVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
           VV+HEL H+   +H + F  L+  Y+ +++  +  LK
Sbjct: 190 VVLHELCHIFYMNHQKDFWSLVEKYMSDYKIRRKKLK 226
>ref|NP_281803.1| (NC_002163) hypothetical protein Cj0620 [Campylobacter jejuni]
 pir||C81410 hypothetical protein Cj0620 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB75256.1| (AL139075) hypothetical protein Cj0620 [Campylobacter jejuni]
          Length = 215

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 53/212 (25%), Positives = 98/212 (46%), Gaps = 20/212 (9%)

Query: 17  KKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQSQRGM 76
           KK IK L + +    G   +S P     +S+   L K   W+ E ++ F       ++ +
Sbjct: 22  KKCIKTLRLRL-NEKGEFVLSIPYFCTFKSVYEFLDKSSSWMNEAKKRF-------EKKV 73

Query: 77  LERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLRE 136
           L+ +      K+Y +  +  TKK +  ++          K   +N+ K L+ + RQ  ++
Sbjct: 74  LKDDELIFLAKKYKIIFDENTKKTYFDKD----------KIICQNKAK-LDLFLRQNAKK 122

Query: 137 KIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHE 196
                + ++ +          I+ MK  WGSCN  K  +  NL+L +   + IEYV++HE
Sbjct: 123 IFTFYLKKWSQKTGLFYTHLSIKNMKTRWGSCNHNKAYVNLNLKLIQKSLRAIEYVILHE 182

Query: 197 LLHLKTRHHNEYFRDLLSLYLPNW-QRAKASL 227
           + HLK  +H++ F   +  ++ ++ QR K  L
Sbjct: 183 ISHLKFPNHSKEFYTFIEHFMSDFRQREKEFL 214
>ref|NP_326157.1| (NC_002771) conserved hypothetical protein [Mycoplasma pulmonis]
 emb|CAC13499.1| (AL445564) conserved hypothetical protein [Mycoplasma pulmonis]
          Length = 177

 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 31/131 (23%), Positives = 68/131 (51%), Gaps = 4/131 (3%)

Query: 98  KKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEK----ILNESI 153
           +K F +     LI+    K       + ++ Y +++++E     +   +K    I+    
Sbjct: 44  RKTFFIYKNNILIIPDLSKVIRVKEYEKIDIYLKKIIKEIFLEYLKVRQKYWSLIMGVPE 103

Query: 154 QSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLL 213
            S ++++  R W S  ++K+ +++ L+ +    + I+Y+++HEL H K ++H+  F  ++
Sbjct: 104 HSIEVREKNRSWASNYVSKKKIVYALKSSSKSYEWIDYLIIHELAHYKEQNHSSNFWKIV 163

Query: 214 SLYLPNWQRAK 224
           SLY PNW+  K
Sbjct: 164 SLYCPNWKAMK 174
>ref|NP_276076.1| (NC_000916) unknown [Methanothermobacter thermautotrophicus]
           [Methanothermobacter thermautotrophicus str. Delta H]
 pir||G69225 hypothetical protein MTH939 - Methanobacterium thermoautotrophicum
           (strain Delta H)
 gb|AAB85437.1| (AE000868) unknown [Methanothermobacter thermautotrophicus str.
           Delta H]
          Length = 188

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 33/118 (27%), Positives = 62/118 (51%), Gaps = 3/118 (2%)

Query: 113 VHQKTSLENRLKVLENYYRQ--VLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNI 170
           +H+   +  R   +E  YR+   LR  +   ++ Y  +L       + ++M+  WGSC+ 
Sbjct: 59  IHEFHEMLERASDMELEYRRDKELRSLVSGFLDHYSDVLGVEYGRVRFRRMRSRWGSCS- 117

Query: 171 AKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
           ++  L FN  L+ +P + +EYVV+HEL HL+  +H+  F  +L   +P+    +  L+
Sbjct: 118 SRGNLSFNTLLSHLPDRMVEYVVLHELAHLREMNHSPRFWGILESEMPDCTERRRMLR 175
>ref|NP_360041.1| (NC_003103) unknown [Rickettsia conorii]
 gb|AAL02942.1| (AE008604) unknown [Rickettsia conorii]
          Length = 230

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 47/214 (21%), Positives = 100/214 (45%), Gaps = 11/214 (5%)

Query: 15  IEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQSQR 74
           I ++  K  +I++        +  PL +  E     L+ + +W++++ +  +    + + 
Sbjct: 17  IVRRSSKAKNIAIRITSKGAELVLPLKVKAEKGHNFLLSQEYWVRQKLRRNVTAIPKDE- 75

Query: 75  GMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVL 134
                +   + GK Y +    ++K    L +     L V+  + +  +L + E + ++ L
Sbjct: 76  -----DKISILGKSYEIIHIDSSKNQIKLNDST---LEVYCCSQVLKKLSI-EVFLKKKL 126

Query: 135 REKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVV 194
             +I+  +    K  N +  + +I +    WGSC  +K  L+FN  +   P + ++Y+V 
Sbjct: 127 LAEIKIIVENISKKHNLTYSNIRIMENVSRWGSC-CSKGNLVFNWRVVLAPFEVLKYLVA 185

Query: 195 HELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
           HE+ HLK  +H++ F +L+    P +Q AK  LK
Sbjct: 186 HEMAHLKEMNHSKNFWELVEDIYPEYQPAKLWLK 219
>ref|NP_654268.1| (NC_003995) DUF45, Protein of unknown function DUF45 [Bacillus
           anthracis A2012] [Bacillus anthracis str. A2012]
          Length = 154

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 30/112 (26%), Positives = 61/112 (53%), Gaps = 2/112 (1%)

Query: 111 LHVHQKTSLENRLK-VLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCN 169
           LH++ K   + +++  L+ +Y +  +  +   I  ++       +S +I    R WG+C+
Sbjct: 29  LHIYVKELKDEKIQQALKRFYYKQCKSLVGKSIKAHQSNFKTKPRSIRITDSSRTWGTCD 88

Query: 170 IAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQ 221
            +   L FN +LA  P++ I+YVVVHE+ H+   +H+  F  L+   +P+++
Sbjct: 89  -SNLQLTFNWKLAMAPQRVIDYVVVHEMCHMVHLNHDRSFWRLVGKIMPDYK 139
>ref|NP_578408.1| (NC_003413) hypothetical protein [Pyrococcus furiosus DSM 3638]
 gb|AAL80803.1| (AE010188) hypothetical protein [Pyrococcus furiosus DSM 3638]
          Length = 223

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 51/215 (23%), Positives = 104/215 (47%), Gaps = 27/215 (12%)

Query: 15  IEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQSQR 74
           + +K +K++ + V   DG++ V  PL   ++ +R  LIK+  WI  +  + + + ++   
Sbjct: 16  VVEKPVKYVTLRVLE-DGTILVVTPL---EQIVREVLIKKKDWILSKI-SIVEEAKE--- 67

Query: 75  GMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVL 134
             L R+   LFGK Y L++             K+ I     + +    ++ L N+ ++ +
Sbjct: 68  --LSRKGFPLFGKFYSLEM-----------GEKFEINREELRITFPG-IEFLRNWIKREI 113

Query: 135 REKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVV 194
           + K +       K    S +   ++ M+  WGS    K ++  N   A +P +   Y+V+
Sbjct: 114 KRKAR----EIAKDFGISPKRIYVKAMRTKWGSATWRK-SITLNFSSAALPEELFHYLVI 168

Query: 195 HELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           HEL HL   +H++ F  L++ Y P++++ +  LK+
Sbjct: 169 HELAHLIELNHSKRFWSLVASYHPDYKKKRRELKK 203
>gb|AAD24685.1|AF083877_5 (AF083877) unknown [Erwinia amylovora]
          Length = 202

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 12/164 (7%)

Query: 30  PDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQ-SQRGMLERESHYLFGKR 88
           PD  V V  P   +D+S+  ++ KR  WI +Q + F NQ    + R  +  ESHY  GK+
Sbjct: 39  PDCRVVVFAPEEADDQSVLGAVKKRGRWIWQQLREFRNQREYITPRQYISGESHYYLGKQ 98

Query: 89  YLLKI-EHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEK 147
           YLLK+     +   V      L + V QK   EN  ++L ++YR   R+  +    R E 
Sbjct: 99  YLLKVLAEPGQIQRVKMLRGRLDVTVRQKEP-ENVRQLLSDWYRSRARDVFR---RRLEA 154

Query: 148 ILNESI-----QSFKIQKMKRIWGSCNIAKRALLFNLELAKVPR 186
           +L +++         I  M+  WGSC+ A R L  N  L K  R
Sbjct: 155 MLEQALWVDVPPPLHILTMQTQWGSCSPAGR-LTLNPNLVKAHR 197
>ref|NP_617886.1| (NC_003552) conserved hypothetical protein [Methanosarcina
           acetivorans str. C2A] [Methanosarcina acetivorans C2A]
 gb|AAM06366.1| (AE011002) conserved hypothetical protein [Methanosarcina
           acetivorans str. C2A] [Methanosarcina acetivorans C2A]
          Length = 130

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 30/101 (29%), Positives = 53/101 (51%), Gaps = 1/101 (0%)

Query: 128 NYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRK 187
           N+Y +   + ++    +Y    ++     KIQ +K  WG+C+   + L FN  +      
Sbjct: 23  NFYHEKAEKVLKQRARKYLLYFDDKPSLIKIQTLKNKWGNCSKTNQ-LRFNWRVIMAKMS 81

Query: 188 GIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
            I+YVVVHEL H K + H++ F + +   LP+++  KA L+
Sbjct: 82  IIDYVVVHELCHTKYKDHSKAFWNEVQKILPDYEERKAWLR 122
>gb|AAM46140.1|AF380136_1 (AF380136) metalloprotease [Helicobacter pylori]
          Length = 206

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 37/154 (24%), Positives = 78/154 (50%), Gaps = 12/154 (7%)

Query: 89  YLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLE------NYYRQVLREKIQTCI 142
           +L + E   KK       KY +LH   +T  +N++ V +      +Y    L++ ++T +
Sbjct: 44  FLKEQEAWLKKTLSAMQEKYSLLHSRLET-YQNKILVFDEVKNANDYTLTELKKILKTYL 102

Query: 143 NRYEKILNESIQS----FKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELL 198
            +   +  + +Q+    F ++   ++ GSC+   R L F L L    ++ I+YV++HEL 
Sbjct: 103 EQKLPLNAQKMQTSYTHFSVRNNAKVLGSCSYHNR-LSFALLLVCAQKEAIDYVIIHELA 161

Query: 199 HLKTRHHNEYFRDLLSLYLPNWQRAKASLKETYL 232
           H   ++H++ F   + ++ PN++  +  LK+  +
Sbjct: 162 HTIHKNHSKNFWRCVQIFCPNYRALREHLKQNII 195
>ref|NP_207599.1| (NC_000915) hypothetical protein [Helicobacter pylori 26695]
 pir||F64620 hypothetical protein HP0806 - Helicobacter pylori (strain 26695)
 gb|AAD07859.1| (AE000592) H. pylori predicted coding region HP0806 [Helicobacter
           pylori 26695]
          Length = 206

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 36/150 (24%), Positives = 77/150 (51%), Gaps = 10/150 (6%)

Query: 89  YLLKIEHTTKKHFVLQNPKYLILHVH-----QKTSLENRLKVLENYYRQVLREKIQTCIN 143
           +L + E   KK F+    K+ +L  +      K  + + +K   +Y    L++ ++T + 
Sbjct: 44  FLKEQEAWLKKTFLSMQEKHSLLRTNLEKYQNKILVFDEVKNANDYTLTELKKILKTYLE 103

Query: 144 RYEKILNESIQS----FKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLH 199
           +   ++ + +Q+    F I+   ++ GSC+   R L F L L    ++ I+YV++HEL H
Sbjct: 104 QKLPLIAQKMQTSYTHFSIRNNAKVLGSCSYHNR-LSFALLLVCAQKEAIDYVIIHELAH 162

Query: 200 LKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
              ++H++ F   + ++ PN++  +  LK+
Sbjct: 163 TIHKNHSKNFWRCVQIFCPNYRALRERLKQ 192
>ref|NP_297587.1| (NC_002488) hypothetical protein [Xylella fastidiosa 9a5c]
 pir||B82823 hypothetical protein XF0294 [imported] - Xylella fastidiosa
           (strain 9a5c)
 gb|AAF83107.1|AE003883_2 (AE003883) hypothetical protein [Xylella fastidiosa 9a5c]
          Length = 114

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 25/68 (36%), Positives = 41/68 (59%), Gaps = 1/68 (1%)

Query: 154 QSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLL 213
           ++ ++Q M R WGSC+      L + +L    ++  +YV+VHELLHL+   H   F+ L+
Sbjct: 27  RAVRVQDMHRKWGSCSSTGTITLAS-DLLDQEQRFQDYVIVHELLHLRFATHGRMFKALM 85

Query: 214 SLYLPNWQ 221
           S Y+P W+
Sbjct: 86  SAYVPGWR 93
>ref|NP_142658.1| (NC_000961) hypothetical protein [Pyrococcus horikoshii]
 pir||A71118 hypothetical protein PH0712 - Pyrococcus horikoshii
 dbj|BAA29803.1| (AP000003) 230aa long hypothetical protein [Pyrococcus horikoshii]
          Length = 230

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 50/215 (23%), Positives = 103/215 (47%), Gaps = 27/215 (12%)

Query: 15  IEKKDIKHLHISVCPPDGSVHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQSQR 74
           + +K +K++ +     DG++ V  P   + E +R  LIK+ +WI  +  + + + ++   
Sbjct: 16  VVEKPVKYVTLRFLE-DGTLLVVTP---SKEIVREVLIKKRNWILSKL-SIIEEAKE--- 67

Query: 75  GMLERESHYLFGKRYLLKIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVL 134
             L  E   LFG+ Y L+I     + F + +   +I++          + VL ++ ++ +
Sbjct: 68  --LAGEGFPLFGRFYSLEIG----EKFEIDDKNRIIIYPG--------IDVLRDWIKKEV 113

Query: 135 REKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVV 194
           + + Q       K    + +   ++ MK  WGS    K   L NL    +P +   Y+V+
Sbjct: 114 KRRAQ----EISKEFGVAPKRIYVRVMKTKWGSTTWRKSVTL-NLSSVALPEELFHYLVI 168

Query: 195 HELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           HEL HL   +H++ F  +++ Y P+++  +  LK+
Sbjct: 169 HELAHLIELNHSKRFWSIVARYHPDYKEKRRELKK 203
>ref|NP_223460.1| (NC_000921) putative [Helicobacter pylori J99]
 pir||E71894 hypothetical protein jhp0742 - Helicobacter pylori (strain J99)
 gb|AAD06314.1| (AE001505) putative [Helicobacter pylori J99]
          Length = 206

 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 32/115 (27%), Positives = 60/115 (51%), Gaps = 15/115 (13%)

Query: 118 SLENRLKVLENYYRQ---VLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRA 174
           +L +  K+L+ Y  Q   ++ +K+QT           S   F I+   ++ GSC+   R 
Sbjct: 90  TLTDLKKILKTYLEQKLPLIAQKMQT-----------SYTHFSIRNNAKVLGSCSYHNR- 137

Query: 175 LLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           L F L L    ++ I+YV++HEL H   ++H++ F   + ++ PN++  +  LK+
Sbjct: 138 LSFALLLVCAKKEAIDYVIIHELAHTIHKNHSKNFWRCVQIFCPNYRALRERLKQ 192
>ref|NP_540932.1| (NC_003317) zinc metallopeptidases [Brucella melitensis]
 gb|AAL53196.1| (AE009634) zinc metallopeptidases [Brucella melitensis]
          Length = 253

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 18/181 (9%)

Query: 59  KEQQQNFLNQNRQSQRGMLERESHYLF---GKRYLLKIEHTTKKHFVLQNP--------K 107
           + + QNFLN++     G +E     L    G R  +KI      H ++  P        +
Sbjct: 68  EREVQNFLNRHE----GWIESRIAKLPDQPGVRAGIKIPIRGVAHLIVHQPGRGTVECIE 123

Query: 108 YLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGS 167
             IL VH   S   R   + +Y ++ +R  I+  + R+   +    ++ + +  K  WGS
Sbjct: 124 GNILLVHGDPSHLPRR--VADYLKREVRRDIEALVVRHTAAVGRKAKAVRFKDTKSRWGS 181

Query: 168 CNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASL 227
           C  +   L F+  +   P   I Y+V HE  HL   +H   F  L     P+ +R KA L
Sbjct: 182 CT-SDGVLSFSWRIGMAPPPVINYLVAHEAAHLIEMNHGPKFWKLCQELCPDTERCKAWL 240

Query: 228 K 228
           K
Sbjct: 241 K 241
>ref|NP_127009.1| (NC_000868) hypothetical protein [Pyrococcus abyssi]
 pir||B75043 hypothetical protein PAB1496 - Pyrococcus abyssi (strain Orsay)
 emb|CAB50239.1| (AJ248287) hypothetical protein [Pyrococcus abyssi]
          Length = 208

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 27/98 (27%), Positives = 52/98 (52%), Gaps = 1/98 (1%)

Query: 131 RQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIE 190
           +++LR+++        + L    +   I+ MKR WGS    + ++  +L  A +PR  + 
Sbjct: 91  KRMLRKEVLNIAGEVGRALKVRPKRVYIKVMKRKWGSTTW-RGSITIDLSAAALPRDLLH 149

Query: 191 YVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
           Y+V HE+ HL   +H + F  L+S + P+++  +  LK
Sbjct: 150 YLVTHEMCHLIEMNHGKKFWSLVSRFHPDYKEKRRELK 187
>ref|NP_105795.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
 dbj|BAB51581.1| (AP003005) hypothetical protein [Mesorhizobium loti]
          Length = 252

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 1/103 (0%)

Query: 126 LENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVP 185
           + ++ ++  +++I+  + ++ + L +  ++ + +     WGSC  ++  L F+  +   P
Sbjct: 139 IADFLKREAKKEIEKLVIKHTEALGKRAKAIRYKDTSSRWGSCT-SEGNLSFSWRIMMAP 197

Query: 186 RKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
           +  I Y+V HE+ HLK  +H   F  L     P+  R K  LK
Sbjct: 198 QPVINYLVAHEVAHLKEMNHGPKFWKLCEKLCPDTDRCKDWLK 240
>ref|NP_541426.1| (NC_003318) zinc metallopeptidases [Brucella melitensis]
 gb|AAL53690.1| (AE009681) zinc metallopeptidases [Brucella melitensis]
          Length = 246

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 44/198 (22%), Positives = 83/198 (41%), Gaps = 14/198 (7%)

Query: 34  VHVSCPLALNDESLRLSLIKRLHWIKEQQQNFLNQNRQS-QRGMLERESHYLFGKRYLLK 92
           V V  P  L+D+ +   + K+  W+  +Q  +     Q   +  +  E+ +  G++Y LK
Sbjct: 38  VRVLAPSDLDDDRVLGIVRKKGAWLLRKQAAYRELEGQPVAKEFVSGETFHYLGRQYRLK 97

Query: 93  I--EHTTKKHFVLQNPKYLILHVH-------QKTSLENRLKVLENYYRQVLREKIQTCIN 143
           +  + T     +      LI  V        Q+ ++ N L+   ++YR    +       
Sbjct: 98  LIPDETAVVTRIAARGSTLIAPVLPNGHASVQRAAVRNGLR---HWYRAHAIQHFPIRAR 154

Query: 144 RYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTR 203
              K L       K+    + WGSC+ A+  +  N  LA  P   ++YV+ HE  H+   
Sbjct: 155 VIAKTLGIPTPIVKVVDQSKRWGSCD-ARGRIRLNWRLAMAPMPLVDYVIAHEACHILEH 213

Query: 204 HHNEYFRDLLSLYLPNWQ 221
           +H+  F   L   +P+++
Sbjct: 214 NHSRRFWRSLEAIMPDYE 231
>ref|NP_384132.1| (NC_003047) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
 emb|CAC41413.1| (AL591782) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
          Length = 251

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)

Query: 120 ENRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNL 179
           E+  + + +Y ++  R +++  +  Y        +S  ++  +  WGSC+ A+  L F+ 
Sbjct: 132 EHLRRRIADYLKKEARSELERLVAVYAGRTGRRARSLSLKDTRSRWGSCS-AEGDLSFSW 190

Query: 180 ELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
            +A  P K I Y+  HE+ HL+  +H   F  L     P  + AK  LK
Sbjct: 191 RIAMAPPKVIAYLAAHEVAHLQEMNHGPRFWALCESLCPETKDAKHWLK 239
>ref|NP_518642.1| (NC_003295) HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
 emb|CAD14049.1| (AL646059) HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
          Length = 288

 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 5/103 (4%)

Query: 126 LENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVP 185
           L+   R++  E++      Y + L     ++ +      WGSC  A   +  N  L   P
Sbjct: 181 LQTQARRLFGERLDV----YAERLGVRHSAYALSSAATRWGSCT-ADGKIRLNWRLVHFP 235

Query: 186 RKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
              I+YVV HEL HLK  +H+  F D +    P ++ A+  L+
Sbjct: 236 LSLIDYVVAHELAHLKEMNHSPRFWDTVESIFPEFREAREQLR 278
>ref|NP_275026.1| (NC_003112) conserved hypothetical protein [Neisseria meningitidis
           MC58]
 pir||H81013 conserved hypothetical protein NMB2035 [imported] - Neisseria
           meningitidis (group B strain MD58)
 gb|AAF42356.1| (AE002553) conserved hypothetical protein [Neisseria meningitidis
           MC58]
          Length = 230

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 34/141 (24%), Positives = 55/141 (38%), Gaps = 15/141 (10%)

Query: 102 VLQNPKYLILHVHQKTSL--------------ENRLKVLENYYRQVLREKIQTCINRYEK 147
           +L + + L L  HQ T +              E +L +L ++  +     +   + R+ +
Sbjct: 81  ILFHGRQLALTAHQDTQILLMPSEIRVPEGAPEKQLALLRDFLERQAHSYLIPRLERHAR 140

Query: 148 ILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNE 207
                  S  +   K  WG C      + FN  L   P    +YV +HEL HL    H+ 
Sbjct: 141 TTQLFPASSSLTSAKTFWGVCR-KTTGIRFNWRLVGAPEYVADYVCIHELCHLAHPDHSP 199

Query: 208 YFRDLLSLYLPNWQRAKASLK 228
            F +L   + P   +AK  LK
Sbjct: 200 AFWELTRRFAPYTPKAKQWLK 220
>ref|NP_078157.1| (NC_002162) conserved hypothetical [Ureaplasma urealyticum]
 pir||E82906 conserved hypothetical UU323 [imported] - Ureaplasma urealyticum
 gb|AAF30732.1|AE002129_8 (AE002129) conserved hypothetical [Ureaplasma urealyticum]
          Length = 231

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 35/136 (25%), Positives = 54/136 (38%), Gaps = 6/136 (4%)

Query: 90  LLKIEHTTKK------HFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCIN 143
           LL I+ TT K      H      K +I    Q  +L N   + +     +        I 
Sbjct: 86  LLGIKFTTIKIKNNNFHCQFNFQKQIIYLYDQNQNLTNTKLLYQKILIYLAEIIFPQIIK 145

Query: 144 RYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTR 203
             + I   +++ +     K  WG  N  K  +  +  L    +  I YVV+HEL H+K +
Sbjct: 146 NAQNITTLTVKKYVFGFYKSQWGVYNKIKHTIGLSYFLVHYDQDIINYVVIHELAHIKYQ 205

Query: 204 HHNEYFRDLLSLYLPN 219
           HH + F D +  Y  N
Sbjct: 206 HHQKSFWDFVLKYCKN 221
>ref|NP_661599.1| (NC_002932) zinc protease, putative [Chlorobium tepidum TLS]
 gb|AAM71941.1| (AE012841) zinc protease, putative [Chlorobium tepidum TLS]
          Length = 248

 Score = 43.1 bits (100), Expect = 0.003
 Identities = 22/94 (23%), Positives = 48/94 (50%), Gaps = 1/94 (1%)

Query: 126 LENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVP 185
           LE + +   + K+   + R   I    +    ++K K  WGSC+ ++  +  NL+L  +P
Sbjct: 133 LEQWLKHRAKLKLGAQLMRLASINGFKVSGVSVKKQKSRWGSCS-SRGNINLNLKLIFLP 191

Query: 186 RKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPN 219
              + Y+++HEL H    +H+  + + ++ + P+
Sbjct: 192 PLLVRYIMIHELCHTLHMNHSARYWETVARFDPD 225
>ref|NP_629342.1| (NC_003888) hypothetical protein [Streptomyces coelicolor A3(2)]
 emb|CAC01324.1| (AL390968) hypothetical protein [Streptomyces coelicolor A3(2)]
          Length = 168

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 165 WGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAK 224
           WGSC  ++ ++  +  L  +P   ++YV++HEL HL    H   F  LL  Y P  +RA+
Sbjct: 89  WGSCTPSEGSIRLSHRLQGMPEYVVDYVLLHELAHLLVPGHGPRFWRLLEAY-PRTERAR 147

Query: 225 ASLK 228
             L+
Sbjct: 148 GYLE 151
>sp|O42287|ITN1_XENLA Intersectin 1
 pir||T09194 adaptor protein intersectin - African clawed frog
 gb|AAC73068.1| (AF032118) intersectin [Xenopus laevis]
          Length = 1270

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/177 (20%), Positives = 82/177 (45%), Gaps = 20/177 (11%)

Query: 53  KRLHWIKEQQQNFLNQNRQSQRGM----------------LERESHYLFGKRYLLKIEHT 96
           ++L W + ++Q  LNQ  + Q  +                L  + H L GK   ++   T
Sbjct: 443 RQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLT 502

Query: 97  TKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEKILNESIQSF 156
           T++H +    K   L + + T L+ +L+  +    +++ EK Q+ I++ +++   S+   
Sbjct: 503 TQRHEIESTNKSRELRIAEITHLQQQLQESQQLLGKMIPEK-QSLIDQLKQVQQNSLHRD 561

Query: 157 KIQKMKRIWGSCNIAKRALLFNL-ELAKVPRKGIEYVVV--HELLHLKTRHHNEYFR 210
            +  +KR   +  I ++ L   L E+ K  R  ++ + V  ++L  L+  ++ + F+
Sbjct: 562 SLLTLKRALETKEIGRQQLRDQLDEVEKETRAKLQEIDVFNNQLKELRELYNKQQFQ 618
>ref|NP_283232.1| (NC_003116) hypothetical protein NMA0403 [Neisseria meningitidis
           Z2491]
 pir||H81956 hypothetical protein NMA0403 [imported] - Neisseria meningitidis
           (group A strain Z2491)
 emb|CAB83703.1| (AL162753) hypothetical protein NMA0403 [Neisseria meningitidis
           Z2491]
          Length = 230

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 33/141 (23%), Positives = 52/141 (36%), Gaps = 15/141 (10%)

Query: 102 VLQNPKYLILHVHQKTSL--------------ENRLKVLENYYRQVLREKIQTCINRYEK 147
           +L + + L L  HQ T +              E +L +L ++  +     +   + R+ +
Sbjct: 81  ILFHGRQLALTAHQDTQILLMPSEIRVPEGAPEKQLALLRDFLERQAHSYLIPRLERHAR 140

Query: 148 ILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNE 207
                     +   K  WG C      + FN  L   P    +YV +HEL HL    H+ 
Sbjct: 141 TTQLFPAPSSLTSAKTFWGVCR-KTTGIRFNWRLVGAPEYVADYVCIHELCHLAHADHSR 199

Query: 208 YFRDLLSLYLPNWQRAKASLK 228
            F  L   + P    AK  LK
Sbjct: 200 AFWALTRRFAPYTPEAKQWLK 220
>gb|AAD24686.1|AF083877_6 (AF083877) unknown [Erwinia amylovora]
          Length = 90

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 17/41 (41%), Positives = 26/41 (62%)

Query: 189 IEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLKE 229
           I+YV++HEL HL   +H+E F  L++  +P W+  K  L E
Sbjct: 40  IDYVILHELCHLAEHNHSERFYRLMAQVMPQWRTIKVRLDE 80
>ref|NP_273283.1| (NC_003112) conserved hypothetical protein [Neisseria meningitidis
           MC58]
 pir||D81223 conserved hypothetical protein NMB0226 [imported] - Neisseria
           meningitidis (group B strain MD58)
 gb|AAF40682.1| (AE002380) conserved hypothetical protein [Neisseria meningitidis
           MC58]
          Length = 230

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 28/137 (20%), Positives = 59/137 (42%), Gaps = 5/137 (3%)

Query: 92  KIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEKILNE 151
           K++  ++ H  + + + L+        +++  ++L    R+ L  +++    ++      
Sbjct: 89  KLDTHSQSHIRITSSEILLPRKETAAQIDHLRRLLNERAREYLLPRLE----KHAAETGL 144

Query: 152 SIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRD 211
           +  +  +   K  WG C      +  N  L   P    +YV +HEL HL+   H+  F  
Sbjct: 145 TPTATDLSNAKTFWGVCR-PHTGIRLNWRLIGTPEYVADYVCIHELCHLRHPDHSPRFWH 203

Query: 212 LLSLYLPNWQRAKASLK 228
           L++   P+   AK+ LK
Sbjct: 204 LVNTLTPHTDNAKSWLK 220
>ref|NP_282887.1| (NC_003116) hypothetical protein NMA0032 [Neisseria meningitidis
           Z2491]
 pir||C81994 hypothetical protein NMA0032 [imported] - Neisseria meningitidis
           (group A strain Z2491)
 emb|CAB72040.1| (AJ391262) hypothetical protein [Neisseria meningitidis]
 emb|CAB83351.1| (AL162752) hypothetical protein NMA0032 [Neisseria meningitidis
           Z2491]
          Length = 230

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 28/137 (20%), Positives = 59/137 (42%), Gaps = 5/137 (3%)

Query: 92  KIEHTTKKHFVLQNPKYLILHVHQKTSLENRLKVLENYYRQVLREKIQTCINRYEKILNE 151
           K++  ++ H  + + + L+        +++  ++L    R+ L  +++    ++      
Sbjct: 89  KLDTHSQSHIRITSSEILLPRKETAAQIDHLRRLLNERAREYLLPRLE----KHAAETGL 144

Query: 152 SIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNEYFRD 211
           +  +  +   K  WG C      +  N  L   P    +YV +HEL HL+   H+  F  
Sbjct: 145 TPAATDLSNAKTFWGVCR-PHTGIRLNWRLIGTPEYVADYVCIHELCHLRHPDHSPRFWH 203

Query: 212 LLSLYLPNWQRAKASLK 228
           L++   P+   AK+ LK
Sbjct: 204 LVNTLTPHTDNAKSWLK 220
>gb|AAD38302.1|AF036242_2 (AF036242) unknown [Neisseria meningitidis]
          Length = 230

 Score = 41.2 bits (95), Expect = 0.010
 Identities = 32/141 (22%), Positives = 53/141 (36%), Gaps = 15/141 (10%)

Query: 102 VLQNPKYLILHVHQKTSL--------------ENRLKVLENYYRQVLREKIQTCINRYEK 147
           +L + + L L  HQ T +              E +L +L ++  +     +   + R+ +
Sbjct: 81  ILFHGRQLALTAHQDTQILLMPSEIRVPEGAPEKQLALLRDFLERQAHSYLIPRLERHAR 140

Query: 148 ILNESIQSFKIQKMKRIWGSCNIAKRALLFNLELAKVPRKGIEYVVVHELLHLKTRHHNE 207
                     +   K  WG C      +  N  L   P    +YV +HEL HL    H+ 
Sbjct: 141 TTQLFPAPSSLTSAKTFWGVCR-KTTGIRLNWRLVGAPEYVADYVCIHELCHLAHPDHSP 199

Query: 208 YFRDLLSLYLPNWQRAKASLK 228
            F +L   + P   +AK  LK
Sbjct: 200 AFWELTRRFAPYTPKAKQWLK 220
>ref|NP_353056.1| (NC_003062) AGR_C_25p [Agrobacterium tumefaciens] [Agrobacterium
           tumefaciens str. C58 (Cereon)]
 ref|NP_530731.1| (NC_003304) conserved hypothetical protein [Agrobacterium
           tumefaciens str. C58 (U. Washington)]
 gb|AAK85841.1| (AE007944) AGR_C_25p [Agrobacterium tumefaciens str. C58 (Cereon)]
 gb|AAL41047.1| (AE008976) conserved hypothetical protein [Agrobacterium
           tumefaciens str. C58 (U. Washington)]
          Length = 255

 Score = 41.2 bits (95), Expect = 0.010
 Identities = 23/109 (21%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 120 ENRLKVLENYYRQVLREKIQTCINRYEKILNESIQSFKIQKMKRIWGSCNIAKRALLFNL 179
           E+  + +  + ++  +  ++  +  + +     ++S  ++  +  WGSC+     L F+ 
Sbjct: 136 EHLRRRIATFLKKEAKADLERLVAIHGRAAGRPVRSISMKDTRSRWGSCSHDGN-LSFSW 194

Query: 180 ELAKVPRKGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKASLK 228
            +   P + I+Y+  HE+ HL   +H   F  L     P+   AK  LK
Sbjct: 195 RIVMAPDRVIDYLAAHEVAHLSEMNHGPKFWALCEKLCPHTSEAKDWLK 243
  Database: /home/scwang/download_20020708_db/nr
    Posted date:  Aug 7, 2002 12:55 PM
  Number of letters in database: 324,149,939
  Number of sequences in database:  1,026,957
  
Lambda     K      H
   0.322    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 144,009,287
Number of Sequences: 1026957
Number of extensions: 5465778
Number of successful extensions: 14713
Number of sequences better than 1.0e-02: 42
Number of HSP's better than  0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 14669
Number of HSP's gapped (non-prelim): 43
length of query: 235
length of database: 324,149,939
effective HSP length: 117
effective length of query: 118
effective length of database: 203,995,970
effective search space: 24071524460
effective search space used: 24071524460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 95 (41.2 bits)