BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15645178|ref|NP_207348.1| conserved hypothetical
protein [Helicobacter pylori 26695]
(227 letters)
Database: /home/scwang/download_20020708_db/nr
1,026,957 sequences; 324,149,939 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_207348.1| (NC_000915) conserved hypothetical protein... 440 e-123
ref|NP_223218.1| (NC_000921) putative [Helicobacter pylori ... 422 e-117
ref|NP_281364.1| (NC_002163) putative rRNA methylase [Campy... 172 2e-42
ref|NP_623850.1| (NC_003869) rRNA methylase [Thermoanaeroba... 97 1e-19
ref|NP_345911.1| (NC_003028) spoU rRNA methylase family pro... 90 2e-17
ref|NP_358904.1| (NC_003098) tRNA (guanosine-2'-O-)-methylt... 90 2e-17
ref|NP_273970.1| (NC_003112) RNA methyltransferase, TrmH fa... 88 6e-17
ref|NP_349751.1| (NC_003030) RRNA methylase, YACO B.subtili... 87 2e-16
ref|NP_386829.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANS... 86 3e-16
ref|NP_283895.1| (NC_003116) putative RNA methylase [Neisse... 86 3e-16
ref|NP_268029.1| (NC_002662) tRNA-guanosine methyltransfera... 85 7e-16
ref|NP_269915.1| (NC_002737) putative tRNA/rRNA methyltrans... 84 9e-16
ref|NP_485202.1| (NC_003272) tRNA/rRNA methyltransferase [N... 84 9e-16
ref|NP_294471.1| (NC_001263) RNA methyltransferase, TrmH fa... 84 1e-15
ref|NP_654040.1| (NC_003995) SpoU_methylase, SpoU rRNA Meth... 84 2e-15
ref|NP_532670.1| (NC_003304) tRNA/rRNA metyltransferase [Ag... 83 2e-15
ref|NP_519350.1| (NC_003295) PUTATIVE TRNA/RRNA METHYLTRANS... 83 2e-15
ref|NP_354965.1| (NC_003062) AGR_C_3623p [Agrobacterium tum... 83 2e-15
ref|NP_221026.1| (NC_000963) unknown [Rickettsia prowazekii... 82 3e-15
ref|NP_563340.1| (NC_003366) probable tRNA/rRNA methyltrans... 82 5e-15
ref|NP_420052.1| (NC_002696) spoU rRNA methylase family pro... 81 1e-14
ref|NP_360646.1| (NC_003103) tRNA/rRNA methyltransferase [E... 80 1e-14
ref|NP_539658.1| (NC_003317) 23S ribosomal RNA methyltransf... 79 4e-14
ref|NP_387977.1| (NC_000964) similar to hypothetical protei... 78 7e-14
ref|NP_662510.1| (NC_002932) SpoU rRNA methylase family pro... 78 7e-14
ref|NP_104059.1| (NC_002678) hypothetical protein [Mesorhiz... 78 9e-14
ref|NP_229539.1| (NC_000853) conserved hypothetical protein... 77 1e-13
ref|NP_371055.1| (NC_002758) hypothetical protein [Staphylo... 77 1e-13
ref|NP_385444.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANS... 77 1e-13
gb|AAK15305.1|AF327733_2 (AF327733) YacO [Staphylococcus au... 77 1e-13
ref|NP_348974.1| (NC_003030) RRNA methylase, YSGA B.subtili... 77 2e-13
ref|NP_421117.1| (NC_002696) spoU rRNA methylase family pro... 76 3e-13
ref|NP_404029.1| (NC_003143) putative methylase [Yersinia p... 76 3e-13
ref|NP_469618.1| (NC_003212) similar to conserved hypotheti... 75 4e-13
ref|NP_246892.1| (NC_002663) unknown [Pasteurella multocida... 75 6e-13
ref|NP_463230.1| (NC_003197) putative tRNA/rRNA methyltrans... 75 7e-13
ref|NP_214299.1| (NC_000918) rRNA methylase [Aquifex aeolic... 75 7e-13
ref|NP_441742.1| (NC_000911) hypothetical protein [Synechoc... 74 9e-13
ref|NP_562805.1| (NC_003366) probable rRNA methylase [Clost... 74 1e-12
ref|NP_625830.1| (NC_003888) putative rRNA methylase [Strep... 74 2e-12
ref|NP_458805.1| (NC_003198) probable tRNA/rRNA methyltrans... 73 2e-12
ref|NP_290810.1| (NC_002655) orf, hypothetical protein [Esc... 73 2e-12
ref|NP_539346.1| (NC_003317) 23S ribosomal RNA methyltransf... 72 4e-12
ref|NP_439020.1| (NC_000907) conserved hypothetical protein... 72 4e-12
ref|NP_102094.1| (NC_002678) tRNA/rRNA metyltransferase [Me... 72 5e-12
ref|NP_218549.1| (NC_000919) rRNA methylase, putative [Trep... 71 8e-12
ref|NP_240979.1| (NC_002570) tRNA/rRNA methyltransferase [B... 71 8e-12
ref|NP_253623.1| (NC_002516) probable rRNA methylase [Pseud... 71 8e-12
ref|NP_601840.1| (NC_003450) COG0566:rRNA methylases [Coryn... 70 2e-11
ref|NP_299267.1| (NC_002488) tRNA/rRNA methyltransferase [X... 69 3e-11
ref|NP_243978.1| (NC_002570) rRNA methylase [Bacillus halod... 69 3e-11
ref|NP_232226.1| (NC_002505) RNA methyltransferase, TrmH fa... 69 4e-11
ref|NP_071221.1| (NC_000917) rRNA methylase, putative [Arch... 69 4e-11
gb|EAA02680.1| (AAAB01006210) ebiP448 [Anopheles gambiae st... 69 5e-11
ref|NP_658590.1| (NC_003995) SpoU_methylase, SpoU rRNA Meth... 68 9e-11
ref|NP_326009.1| (NC_002771) TRNA/RRNA METHYLTRANSFERASE [M... 68 9e-11
ref|NP_390743.1| (NC_000964) similar to rRNA methylase [Bac... 68 9e-11
ref|NP_371661.1| (NC_002758) hypothetical protein [Staphylo... 68 9e-11
ref|NP_266763.1| (NC_002662) tRNA/rRNA methyltransferase [L... 67 1e-10
ref|NP_602346.1| (NC_003454) 23S rRNA methyltransferase [Fu... 67 1e-10
pir||S77837 hypothetical protein MC105 - Mycoplasma caprico... 67 2e-10
ref|NP_355393.1| (NC_003062) AGR_C_4428p [Agrobacterium tum... 66 3e-10
ref|NP_533113.1| (NC_003304) RNA methylase [Agrobacterium t... 66 3e-10
ref|NP_606651.1| (NC_003485) putative rRNA methylase [Strep... 66 3e-10
ref|NP_268681.1| (NC_002737) putative rRNA methylase [Strep... 66 3e-10
emb|CAC44352.1| (AJ410308) YfiF protein [Erwinia chrysanthemi] 65 6e-10
ref|NP_336137.1| (NC_002755) rRNA methylase, putative [Myco... 65 7e-10
ref|NP_216160.1| (NC_000962) tsnR [Mycobacterium tuberculos... 64 1e-09
ref|NP_636890.1| (NC_003902) tRNA/rRNA methyltransferase [X... 64 1e-09
ref|NP_420003.1| (NC_002696) spoU rRNA methylase family pro... 64 2e-09
ref|NP_359380.1| (NC_003098) Possible rRNA/tRNA methylase [... 64 2e-09
ref|NP_643623.1| (NC_003919) tRNA/rRNA methyltransferase [X... 64 2e-09
ref|NP_600054.1| (NC_003450) COG0566:rRNA methylases [Coryn... 63 2e-09
ref|NP_301351.1| (NC_002677) putative methyltransferase [My... 63 2e-09
ref|NP_623287.1| (NC_003869) rRNA methylase [Thermoanaeroba... 63 3e-09
ref|NP_662765.1| (NC_002932) SpoU rRNA methylase family pro... 63 3e-09
ref|NP_464743.1| (NC_003210) similar to rRNA methylase [Lis... 62 4e-09
ref|NP_077955.1| (NC_002162) rRNA methylase [Ureaplasma ure... 62 5e-09
ref|NP_212650.1| (NC_001318) rRNA methylase (yacO) [Borreli... 62 5e-09
ref|NP_346400.1| (NC_003028) spoU rRNA Methylase family pro... 62 5e-09
ref|NP_335332.1| (NC_002755) spoU rRNA methylase family pro... 62 6e-09
ref|NP_215396.1| (NC_000962) hypothetical protein Rv0881 [M... 62 6e-09
ref|NP_641901.1| (NC_003919) tRNA/rRNA methyltransferase [X... 62 6e-09
ref|NP_470518.1| (NC_003212) similar to rRNA methylase [Lis... 61 8e-09
ref|XP_126373.1| (XM_126373) similar to hypothetical protei... 60 1e-08
sp|P18644|TSNR_STRCN rRNA (adenosine-2'-O-)-methyltransfera... 60 2e-08
emb|CAB64790.1| (AJ242786) YjfH protein [Burkholderia sp.] 60 2e-08
ref|NP_326135.1| (NC_002771) TRNA/RRNA METHYLTRANSFERASE [M... 60 2e-08
ref|NP_301995.1| (NC_002677) putative rRNA methyltransferas... 60 2e-08
ref|NP_628410.1| (NC_003888) putative tRNA/rRNA methyltrans... 60 2e-08
ref|NP_638511.1| (NC_003902) tRNA/rRNA methyltransferase [X... 60 2e-08
ref|NP_218096.1| (NC_000962) hypothetical protein Rv3579c [... 59 4e-08
ref|NP_338229.1| (NC_002755) spoU rRNA methylase family pro... 59 4e-08
sp|P52391|NHS_STRAS 23S RRNA METHYLTRANSFERASE (23S RRNA ME... 58 7e-08
ref|NP_384496.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANS... 58 9e-08
gb|AAK14417.1|AC087851_9 (AC087851) putative RNA methyltran... 57 1e-07
ref|NP_499333.1| (NM_066932) SpoU rRNA Methylase family [Ca... 57 2e-07
ref|NP_104368.1| (NC_002678) rRNA methylase [Mesorhizobium ... 56 3e-07
ref|NP_457123.1| (NC_003198) putative RNA methyltransferase... 56 3e-07
ref|NP_540715.1| (NC_003317) 23S ribosomal RNA methyltransf... 56 3e-07
ref|NP_531047.1| (NC_003304) rRNA methylase [Agrobacterium ... 56 3e-07
ref|NP_072917.1| (NC_000908) rRNA methylase, putative [Myco... 56 3e-07
ref|NP_353372.1| (NC_003062) AGR_C_593p [Agrobacterium tume... 56 3e-07
ref|NP_406739.1| (NC_003143) putative tRNA/rRNA methyltrans... 55 5e-07
ref|NP_195515.1| (NM_119963) hypothetical protein [Arabidop... 55 5e-07
gb|EAA03105.1| (AAAB01007848) ebiP2005 [Anopheles gambiae s... 55 6e-07
ref|NP_600607.1| (NC_003450) COG0566:rRNA methylases [Coryn... 55 6e-07
ref|NP_197043.1| (NM_121543) rRNA methylase - like protein ... 55 6e-07
dbj|BAB98781.1| (AP005278) rRNA methylases [Corynebacterium... 55 6e-07
gb|AAM28546.1|AF494517_1 (AF494517) putative tRNA/rRNA meth... 54 1e-06
ref|NP_110043.1| (NC_000912) tRNA/rRNA methyltransferase [M... 54 1e-06
ref|NP_294741.1| (NC_001263) rRNA methylase [Deinococcus ra... 54 1e-06
ref|NP_473099.1| (NC_000910) rRNA methylase (SpoU family) (... 54 2e-06
ref|NP_219913.1| (NC_000117) rRNA Methylase (SpoU family) [... 54 2e-06
ref|NP_603772.1| (NC_003454) 23S rRNA methyltransferase [Fu... 53 3e-06
ref|NP_230452.1| (NC_002505) RNA methyltransferase, TrmH fa... 53 3e-06
ref|NP_311474.1| (NC_002695) hypothetical protein [Escheric... 52 4e-06
ref|NP_289139.1| (NC_002655) orf, hypothetical protein [Esc... 52 5e-06
ref|NP_441675.1| (NC_000911) rRNA methylase [Synechocystis ... 52 5e-06
sp|P52393|TSNR_STRLU RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERA... 52 5e-06
ref|NP_078161.1| (NC_002162) rRNA methylase [Ureaplasma ure... 51 9e-06
ref|NP_484219.1| (NC_003272) rRNA methylase [Nostoc sp. PCC... 51 9e-06
ref|NP_596705.1| (NC_003423) putative ribose methyltransfer... 51 1e-05
gb|AAG32066.1| (AF333038) rRNA methyltransferase [Streptomy... 49 3e-05
ref|NP_625873.1| (NC_003888) putative rRNA methylase [Strep... 49 4e-05
gb|AAL32808.1| (AY062730) Unknown protein [Arabidopsis thal... 49 4e-05
ref|NP_179577.1| (NM_127545) hypothetical protein [Arabidop... 49 4e-05
ref|NP_218494.1| (NC_000919) conserved hypothetical protein... 48 7e-05
ref|NP_662143.1| (NC_002932) SpoU rRNA methylase family pro... 48 9e-05
ref|NP_224726.1| (NC_000922) rRNA Methylase [Chlamydophila ... 48 9e-05
ref|NP_005637.2| (NM_005646) TAR RNA binding protein 1; TAR... 47 1e-04
ref|XP_002084.6| (XM_002084) TAR RNA binding protein 1 [Hom... 47 1e-04
ref|NP_224856.1| (NC_000922) rRNA Methylase [Chlamydophila ... 46 4e-04
ref|NP_212186.1| (NC_001318) spoU protein (spoU) [Borrelia ... 45 5e-04
dbj|BAA16467.1| (D90886) similar to [SwissProt Accession Nu... 45 6e-04
ref|NP_297057.1| (NC_002620) spoU rRNA methylase family pro... 44 0.001
ref|NP_246796.1| (NC_002663) unknown [Pasteurella multocida... 43 0.002
ref|NP_014844.1| (NC_001147) Ribose methyltransferase for m... 43 0.002
ref|NP_495375.1| (NM_062974) rRNA methylase [Caenorhabditis... 42 0.007
>ref|NP_207348.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
26695]
pir||A64589 conserved hypothetical protein HP0553 - Helicobacter pylori
(strain 26695)
gb|AAD07619.1| (AE000569) conserved hypothetical protein [Helicobacter pylori
26695]
Length = 227
Score = 440 bits (1132), Expect = e-123
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG
Sbjct: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
Query: 61 GNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAK 120
GNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAK
Sbjct: 61 GNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAK 120
Query: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCA 180
ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCA
Sbjct: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCA 180
Query: 181 LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN
Sbjct: 181 LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
>ref|NP_223218.1| (NC_000921) putative [Helicobacter pylori J99]
pir||G71924 hypothetical protein jhp0500 - Helicobacter pylori (strain J99)
gb|AAD06078.1| (AE001483) putative [Helicobacter pylori J99]
Length = 227
Score = 422 bits (1084), Expect = e-117
Identities = 217/227 (95%), Positives = 219/227 (95%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
MQAVIYGKQVI HLLNSH EKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG
Sbjct: 1 MQAVIYGKQVITHLLNSHHEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
Query: 61 GNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAK 120
GNHQGVLAKVELPLA SLKE+KKAQKLLVLCGITDV NIGGIFRSAYCLGM GVILDFA+
Sbjct: 61 GNHQGVLAKVELPLAASLKEIKKAQKLLVLCGITDVRNIGGIFRSAYCLGMDGVILDFAR 120
Query: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCA 180
E AYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQ ENLSLKKCA
Sbjct: 121 EFAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQAENLSLKKCA 180
Query: 181 LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
LFLGSEHEGLSKKILAKMD ILSVKMRRDFDSLNVSVAAGILMDKIN
Sbjct: 181 LFLGSEHEGLSKKILAKMDAILSVKMRRDFDSLNVSVAAGILMDKIN 227
>ref|NP_281364.1| (NC_002163) putative rRNA methylase [Campylobacter jejuni]
pir||A81433 probable rRNA methylase Cj0153c [imported] - Campylobacter jejuni
(strain NCTC 11168)
emb|CAB72637.1| (AL139074) putative rRNA methylase [Campylobacter jejuni]
Length = 227
Score = 172 bits (437), Expect = 2e-42
Identities = 96/224 (42%), Positives = 138/224 (60%), Gaps = 2/224 (0%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNH 63
++YGKQ+ ++L H++ + E+YL+KE DK F + K+ I K+D K AQ+ AKGGNH
Sbjct: 2 IVYGKQIFFYILEYHKDCINELYLAKECDKITFSKIAKSGFKIKKLDFKTAQAYAKGGNH 61
Query: 64 QGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELA 123
QG L ++ +L E+KK +++L GI+DVGNIG I R+AY LG+G +I ++LA
Sbjct: 62 QGFLLDIKESSFANLNEIKKNDFIVMLYGISDVGNIGAITRTAYALGVGALIF-IGEKLA 120
Query: 124 YEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS-QIENLSLKKCALF 182
EG++R+S G DLP + + L +INELK GF + G +S K L
Sbjct: 121 MEGVIRTSSGAALDLPIVISNDALSVINELKQVGFYFYASDGSGKEIHSVKISNGKKVLV 180
Query: 183 LGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
LGSE GLS KI+ K D + + M+ +FDSLNVS A IL D++
Sbjct: 181 LGSEGFGLSSKIVKKCDECVGIAMKNNFDSLNVSAAFAILCDRM 224
>ref|NP_623850.1| (NC_003869) rRNA methylase [Thermoanaerobacter tengcongensis]
gb|AAM25454.1| (AE013173) rRNA methylase [Thermoanaerobacter tengcongensis]
Length = 247
Score = 97.1 bits (240), Expect = 1e-19
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 13/235 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEID---KKLFFALKKACPNIIKVDNKKAQSLAKG 60
+IYG+ ++ + S +E +++IY+SK K+ K+A + D+ + LA+
Sbjct: 6 IIYGRNPVIEAIRSGKE-IEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKRLAQT 64
Query: 61 GNHQGVLAKVEL-------PLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGG 113
NHQGV+A L + +E K+ LL+L ITD N+G I RSA G+ G
Sbjct: 65 PNHQGVVAVGALYKYFDVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAFGVHG 124
Query: 114 VILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE 172
VI+ + +V++S G + + + + N I +LK G +G + E
Sbjct: 125 VIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINSTIRDLKEKGLWIIGTDAKAEKSFE 184
Query: 173 NLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
L AL +GSE +G+S+ +L D ++ + M+ +SLN SVAA ILM I
Sbjct: 185 ELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNI 239
>ref|NP_345911.1| (NC_003028) spoU rRNA methylase family protein [Streptococcus
pneumoniae TIGR4]
gb|AAK75551.1| (AE007442) spoU rRNA methylase family protein [Streptococcus
pneumoniae TIGR4]
Length = 242
Score = 89.7 bits (221), Expect = 2e-17
Identities = 64/233 (27%), Positives = 115/233 (48%), Gaps = 11/233 (4%)
Query: 4 VIYGKQVIMHLL---NSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
++YG + L ++ LQE K ++K A +K +I K + +G
Sbjct: 6 IVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELATEKKV-SISWTSKKSLSEITEG 64
Query: 61 GNHQGVLAKV------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
HQG + +V EL ++ ++ LL+L G+TD N+G I R+A + GV
Sbjct: 65 AVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDGLTDPHNLGSILRTADATNVSGV 124
Query: 115 ILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ + + +V +++ G + +P + + N +++LK GF G M G+ +
Sbjct: 125 IIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQTLDKLKDEGFWTFGTDMNGTPCHKW 184
Query: 174 LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ K AL +G+E +G+S I ++D ++++ M SLN SVAA ILM ++
Sbjct: 185 NTKGKIALIIGNEGKGISSNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEV 237
>ref|NP_358904.1| (NC_003098) tRNA (guanosine-2'-O-)-methyltransferase, TrmH family
[Streptococcus pneumoniae R6]
gb|AAL00115.1| (AE008502) tRNA (guanosine-2'-O-)-methyltransferase, TrmH family
[Streptococcus pneumoniae R6]
Length = 253
Score = 89.7 bits (221), Expect = 2e-17
Identities = 64/233 (27%), Positives = 115/233 (48%), Gaps = 11/233 (4%)
Query: 4 VIYGKQVIMHLL---NSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
++YG + L ++ LQE K ++K A +K +I K + +G
Sbjct: 17 IVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELATEKKV-SISWTSKKSLSEMTEG 75
Query: 61 GNHQGVLAKV------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
HQG + +V EL ++ ++ LL+L G+TD N+G I R+A + GV
Sbjct: 76 AVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDGLTDPHNLGSILRTADATNVSGV 135
Query: 115 ILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ + + +V +++ G + +P + + N +++LK GF G M G+ +
Sbjct: 136 IIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQTLDKLKDEGFWTFGTDMNGTPCHKW 195
Query: 174 LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ K AL +G+E +G+S I ++D ++++ M SLN SVAA ILM ++
Sbjct: 196 NTKGKIALIIGNEGKGISSNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEV 248
>ref|NP_273970.1| (NC_003112) RNA methyltransferase, TrmH family [Neisseria
meningitidis MC58]
pir||F81141 RNA methyltransferase, TrmH family NMB0931 [imported] - Neisseria
meningitidis (group B strain MD58)
gb|AAF41338.1| (AE002444) RNA methyltransferase, TrmH family [Neisseria
meningitidis MC58]
Length = 250
Score = 88.2 bits (217), Expect = 6e-17
Identities = 65/235 (27%), Positives = 117/235 (49%), Gaps = 11/235 (4%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSK-EIDKKLFFALKKACPNIIKV---DNKKAQSL 57
Q IYG + L + + + E+Y+ + + D + L+KA I+V D + ++
Sbjct: 4 QRPIYGFHAVNARLWQNPKSIVELYIQEGKSDARTREVLEKAANENIRVYFADADRLNAI 63
Query: 58 AKGGNHQGVL-----AKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMG 112
+KG HQGV+ +K + L L+ + + LL+L GITD N+G R+A +G+
Sbjct: 64 SKGARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVH 123
Query: 113 GVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
VI K V + + G +P+ + N + ELK G +G M G S +
Sbjct: 124 AVIAPKDKSAGLNATVSKVACGAAETVPYITVTNLARTLRELKEYGIWIIGTDMSGESDL 183
Query: 172 ENLSLKKCALF-LGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDK 225
+ +L A + +G+E +G+ + D ++S+ M +S+NVSV+AG+++ +
Sbjct: 184 YHCNLPDSAAWVMGNEGDGMRRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSE 238
>ref|NP_349751.1| (NC_003030) RRNA methylase, YACO B.subtilis ortholog [Clostridium
acetobutylicum]
gb|AAK81091.1|AE007810_10 (AE007810) RRNA methylase, YACO B.subtilis ortholog [Clostridium
acetobutylicum]
Length = 252
Score = 86.7 bits (213), Expect = 2e-16
Identities = 71/236 (30%), Positives = 115/236 (48%), Gaps = 14/236 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKV---DNKKAQSLAKG 60
+I G+ ++ L S Q + S + + + L KA I V D KK ++ G
Sbjct: 9 LIEGRNAVIEALKSDSTIEQVLVSSGKSEGSINVILAKAKEKGIPVKYVDRKKLDKISNG 68
Query: 61 GNHQGVLAKVELP--------LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMG 112
G HQGV+A + P + ++ KE + +LVL I D N+G I R+A G+
Sbjct: 69 GVHQGVIA-ISTPYNYCDVDDIILNAKEKNEDPFILVLDEIEDPHNLGSIIRTAELCGVH 127
Query: 113 GVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
G+I+ + + V ++S G + + + + N I++LK G GA + G +
Sbjct: 128 GIIIPKRRNVGVTPTVYKTSAGAVKYVKIAKVSNINLAIDKLKKEGIWVYGAEIDGENYC 187
Query: 172 ENLSLKKC-ALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
N ++ AL +GSE G+SK K D ++ + M +SLN SVAAGI+M +I
Sbjct: 188 YNQNMTGALALVIGSEGRGISKLTKQKCDVLVKIPMVGKVNSLNASVAAGIVMYEI 243
>ref|NP_386829.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
emb|CAC47302.1| (AL591791) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
Length = 275
Score = 85.9 bits (211), Expect = 3e-16
Identities = 55/170 (32%), Positives = 96/170 (56%), Gaps = 7/170 (4%)
Query: 63 HQGVLAKVELPLAVS----LKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
H+GVLA A + + ++ +L CGI++ N+G +FR+A G+ V++D
Sbjct: 100 HRGVLALGRRDAAPGRDALIAGLPQSSLVLAACGISNHDNMGSLFRNAAAFGVDAVLMDS 159
Query: 119 AK-ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL-SL 176
+ Y +R S+G + LPF+ +LI L+T+GF+ G S +G++ I +
Sbjct: 160 TSCDPMYRKAIRVSVGSVLTLPFAREGTAAELIERLQTAGFVVWGLSPRGTADINAIPPA 219
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ AL +G+E EGL + IL+++ T ++ R DSLNV++AAGI + ++
Sbjct: 220 PRTALLVGTEGEGLPETILSQIRT-ARIRQRPGLDSLNVAMAAGIALHQV 268
>ref|NP_283895.1| (NC_003116) putative RNA methylase [Neisseria meningitidis Z2491]
pir||B81879 probable RNA methylase NMA1127 [imported] - Neisseria meningitidis
(group A strain Z2491)
emb|CAB84388.1| (AL162755) putative RNA methylase [Neisseria meningitidis Z2491]
Length = 261
Score = 85.9 bits (211), Expect = 3e-16
Identities = 64/235 (27%), Positives = 117/235 (49%), Gaps = 11/235 (4%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSK-EIDKKLFFALKKACPNIIKV---DNKKAQSL 57
Q IYG + L + + + E+Y+ + + D + L+KA I+V D + ++
Sbjct: 15 QRPIYGFHAVNARLWQNPKSIVELYIQEGKSDARTREVLEKAANENIRVYFADADRLNAI 74
Query: 58 AKGGNHQGVL-----AKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMG 112
+KG HQGV+ +K + L L+ + + LL+L GITD N+G R+A +G+
Sbjct: 75 SKGARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVH 134
Query: 113 GVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
VI K V + + G +P+ + N + ELK G +G M G++ +
Sbjct: 135 AVIAPKDKSAGLNATVSKVASGAAETVPYITVTNLARTLRELKEYGIWIIGTDMGGNADL 194
Query: 172 ENLSLKKCALF-LGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDK 225
+ L A + +G+E +G+ + D ++S+ M +S+NVSV+AG+++ +
Sbjct: 195 YHCDLPDSAAWVMGNEGDGMRRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSE 249
>ref|NP_268029.1| (NC_002662) tRNA-guanosine methyltransferase (EC 2.1.1.34)
[Lactococcus lactis subsp. lactis]
gb|AAK05970.1|AE006417_2 (AE006417) tRNA-guanosine methyltransferase (EC 2.1.1.34)
[Lactococcus lactis subsp. lactis]
Length = 242
Score = 84.7 bits (208), Expect = 7e-16
Identities = 65/234 (27%), Positives = 113/234 (47%), Gaps = 13/234 (5%)
Query: 4 VIYGKQVIMHLLNS---HQEKLQEIYLSKEIDK-KLFFALKKACPNIIKVDNKKAQSLAK 59
+IYG + LN ++ +QE K ++K K LKK NI + L +
Sbjct: 6 LIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARLKKV--NISWTPKTELNKLTE 63
Query: 60 GGNHQGVLAKVELPLAVSLKEV------KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGG 113
G HQG +A+V L+++ K +L+L +TD N+G I R+A G+
Sbjct: 64 NGVHQGFMARVSEFAYADLEKILPALAEKSDATILILDELTDPHNLGSIARTADATGVDA 123
Query: 114 VILDFAKELAYEGI-VRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE 172
+I+ + + V++S G + +P + N +++LK + F G M G+ +
Sbjct: 124 IIIPKHRAVGITSTAVKASTGALQHVPIVRVTNLSQTLDKLKAANFWVFGTDMDGTVYSK 183
Query: 173 NLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ K AL +G+E G+ + + ++D ++++ M SLN SVAA ILM +I
Sbjct: 184 WNTKGKVALIIGNEGHGIGQNLKKQVDEMITIPMTGHVQSLNASVAASILMYEI 237
>ref|NP_269915.1| (NC_002737) putative tRNA/rRNA methyltransferase [Streptococcus
pyogenes] [Streptococcus pyogenes M1 GAS]
ref|NP_607987.1| (NC_003485) putative tRNA/rRNA methyltransferase [Streptococcus
pyogenes MGAS8232]
gb|AAK34636.1| (AE006617) putative tRNA/rRNA methyltransferase [Streptococcus
pyogenes M1 GAS]
gb|AAL98486.1| (AE010104) putative tRNA/rRNA methyltransferase [Streptococcus
pyogenes MGAS8232]
Length = 248
Score = 84.3 bits (207), Expect = 9e-16
Identities = 62/233 (26%), Positives = 111/233 (47%), Gaps = 11/233 (4%)
Query: 4 VIYGKQVIMHLLNSHQEK---LQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKG 60
++YG + L ++ +QE K++D A +K I K + G
Sbjct: 12 IVYGVHAVTESLQANTGNKLYIQEDLRGKKVDNIKSLATQKKVA-ISWTPKKTLSQMTDG 70
Query: 61 GNHQGVLAKVELPLAVSLKEVKKAQK------LLVLCGITDVGNIGGIFRSAYCLGMGGV 114
HQG + +V + E+ + + +L+L G+TD N+G I R+A + GV
Sbjct: 71 AVHQGFVLRVSAFAYTDVDEILEIAEQEANPLILILDGLTDPHNLGSILRTADATNVCGV 130
Query: 115 ILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ + + +V ++S G + +P + + N +++LK GF G M G+
Sbjct: 131 IIPKHRSVGVTPVVSKTSTGAVEHIPIARVTNLSQTLDKLKARGFWIFGTDMNGTPSDCW 190
Query: 174 LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ K AL +G+E +G+S I ++D ++++ M SLN SVAA ILM ++
Sbjct: 191 NTNGKLALVIGNEGKGISTNIKKQVDEMITIPMNGHVQSLNASVAAAILMYEV 243
>ref|NP_485202.1| (NC_003272) tRNA/rRNA methyltransferase [Nostoc sp. PCC 7120]
dbj|BAB73116.1| (AP003584) tRNA/rRNA methyltransferase [Nostoc sp. PCC 7120]
Length = 335
Score = 84.3 bits (207), Expect = 9e-16
Identities = 64/236 (27%), Positives = 115/236 (48%), Gaps = 14/236 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEI--DKKLFFALKKACPN---IIKVDNKKAQSLA 58
+IYG+ ++ L + Q L I+++ + D + + +A N I +VD K+ +
Sbjct: 83 IIYGRHPVLSALQN-QRGLNRIWVTPRLRYDPRFHNLILQAKDNGAVIDEVDTKRLDQIT 141
Query: 59 KGGNHQGVLAKVELPLAVSLKEVKKAQK------LLVLCGITDVGNIGGIFRSAYCLGMG 112
NHQG+ A++ + L E+ K ++V ITD N+G I R+A +G
Sbjct: 142 DQANHQGIAAQIAPYSYIDLYELIAQAKTVTDPVIVVADSITDPHNLGAIIRTAEAIGAQ 201
Query: 113 GVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
G+++ + +V+ + G + + P + + N + +LK +GF G + GS +
Sbjct: 202 GLVIPQRRASGITSTVVKVAAGALENFPVARVVNLGRALEDLKEAGFWIYGTAAGGSEPL 261
Query: 172 ENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+S + L +GSE EGLS D ++S+ + SLN SVAAG+ + +I
Sbjct: 262 HTVSFRGPIVLVIGSEGEGLSMLTQRSCDVLVSIPLMGKTPSLNASVAAGMALYEI 317
>ref|NP_294471.1| (NC_001263) RNA methyltransferase, TrmH family [Deinococcus
radiodurans]
pir||E75481 RNA methyltransferase, TrmH family - Deinococcus radiodurans
(strain R1)
gb|AAF10325.1|AE001930_6 (AE001930) RNA methyltransferase, TrmH family [Deinococcus
radiodurans]
Length = 246
Score = 84.0 bits (206), Expect = 1e-15
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 9/170 (5%)
Query: 63 HQGVLAKVE------LPLAVSLKEVKKAQKLLVLC-GITDVGNIGGIFRSAYCLGMGGVI 115
HQGV+A+VE + + E A L+VL G+TD N G I RSA LG GV+
Sbjct: 63 HQGVVAEVEELQWATVDDILDRAEASGAPLLMVLLDGVTDPRNFGAIIRSAEVLGAHGVV 122
Query: 116 LDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL 174
++ + +V +++ G LP + N LI++LK G GA+ + + +
Sbjct: 123 VEERRSAPLSPVVAKTAAGATAYLPVAQTKNLPRLIDQLKADGVWVYGAAGEAAQDVTRT 182
Query: 175 SLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K AL +G+E EG+ + + K D ++S+ +R SLN SVAAGIL+
Sbjct: 183 DFSGKAALVIGAEGEGMRRLVREKCDVLVSIPVRGQVQSLNASVAAGILL 232
>ref|NP_654040.1| (NC_003995) SpoU_methylase, SpoU rRNA Methylase family [Bacillus
anthracis A2012] [Bacillus anthracis str. A2012]
Length = 247
Score = 83.6 bits (205), Expect = 2e-15
Identities = 69/234 (29%), Positives = 118/234 (49%), Gaps = 13/234 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDK---KLFFALKKACPNIIKVDNKKAQSLAKGG 61
I G+ ++ L S ++ + +I++++ K ++ AL K I++ KK G
Sbjct: 6 IIGRNPVIEALRSGRD-INKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEG 64
Query: 62 NHQGVLAKVELPLAVSLKEV-KKAQK------LLVLCGITDVGNIGGIFRSAYCLGMGGV 114
NHQGV+A+V L+++ K A+K L+L I D N+G I R+A G G+
Sbjct: 65 NHQGVIAQVAAYQYAELEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGI 124
Query: 115 ILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ + + + ++S G + +P + + N I+ELK G G +G + N
Sbjct: 125 IIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTIDELKERGLWIAGTDAKGKTDYRN 184
Query: 174 LSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
L K L +GSE +G+S+ I K D ++++ M SLN SVAA +LM ++
Sbjct: 185 LDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEV 238
>ref|NP_532670.1| (NC_003304) tRNA/rRNA metyltransferase [Agrobacterium tumefaciens
str. C58 (U. Washington)]
gb|AAL42986.1| (AE009151) tRNA/rRNA metyltransferase [Agrobacterium tumefaciens
str. C58 (U. Washington)]
Length = 263
Score = 83.2 bits (204), Expect = 2e-15
Identities = 66/227 (29%), Positives = 109/227 (47%), Gaps = 6/227 (2%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGG 61
Q +YG + L++ Q +L ++ ++ +L A P +++ + + G
Sbjct: 26 QVHLYGLHTVRAALSNPQRQLIKLSVTLNAFARLDIGEADAQPFPVEIVSPQEIDKVLGP 85
Query: 62 N--HQGVLAKVELPLAVS-LKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
HQGV+ + PL V L +KK+ +LVL +TD N+G I RSA G VI
Sbjct: 86 EAIHQGVMLETR-PLPVKKLDALKKSPLILVLDQVTDPHNVGAIMRSAVAFNAGAVITTI 144
Query: 119 AKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE-NLSL 176
G++ +S+ G + +P+ + N D + EL GF +G +G + IE +
Sbjct: 145 RHSPTESGVLAKSASGALELIPYIQITNLADTLGELHKLGFFSVGLDSEGPAPIEQTFTG 204
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K AL LG+E +GL +K + + + M + SLNVS AA I +
Sbjct: 205 AKIALVLGAEGKGLRQKTRETVSALARLDMPGEIKSLNVSNAAAIAL 251
>ref|NP_519350.1| (NC_003295) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN [Ralstonia
solanacearum]
emb|CAD14931.1| (AL646063) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN [Ralstonia
solanacearum]
Length = 249
Score = 83.2 bits (204), Expect = 2e-15
Identities = 66/231 (28%), Positives = 110/231 (47%), Gaps = 11/231 (4%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYL-SKEIDKKLFFALKKACP---NIIKVDNKKAQSLAK 59
++ G + L + EIY + D+++ LK A +I DN++ + +A
Sbjct: 6 LLIGFHAVTARLRHDARSIDEIYFEANRRDRRMQDFLKAAEAAGVRMIPADNERLRGIAG 65
Query: 60 GGNHQGVLAKVE-LPLAVSLKE----VKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
HQGV+AK E L LA++L E ++ LLVL G+TD N+G R A G V
Sbjct: 66 TDRHQGVVAKAEALSLALNLDELLDGIEGPPLLLVLDGVTDPHNLGACLRVADAAGAHAV 125
Query: 115 ILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I + + V + + G +P+ + N + EL+ G +G + + +
Sbjct: 126 IAPKDRSVGINTTVAKVASGAAETVPYITVTNLARTLRELQQRGVWVIGTADEAEQDLYR 185
Query: 174 LSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K AL +G+E EG+ + DT++S+ M +SLNVSVA+G+ +
Sbjct: 186 ADFKGPIALVMGAEGEGMRRLTRETCDTLVSIPMAGSVESLNVSVASGVCL 236
>ref|NP_354965.1| (NC_003062) AGR_C_3623p [Agrobacterium tumefaciens] [Agrobacterium
tumefaciens str. C58 (Cereon)]
gb|AAK87750.1| (AE008116) AGR_C_3623p [Agrobacterium tumefaciens str. C58
(Cereon)]
Length = 295
Score = 83.2 bits (204), Expect = 2e-15
Identities = 66/227 (29%), Positives = 109/227 (47%), Gaps = 6/227 (2%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGG 61
Q +YG + L++ Q +L ++ ++ +L A P +++ + + G
Sbjct: 58 QVHLYGLHTVRAALSNPQRQLIKLSVTLNAFARLDIGEADAQPFPVEIVSPQEIDKVLGP 117
Query: 62 N--HQGVLAKVELPLAVS-LKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
HQGV+ + PL V L +KK+ +LVL +TD N+G I RSA G VI
Sbjct: 118 EAIHQGVMLETR-PLPVKKLDALKKSPLILVLDQVTDPHNVGAIMRSAVAFNAGAVITTI 176
Query: 119 AKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE-NLSL 176
G++ +S+ G + +P+ + N D + EL GF +G +G + IE +
Sbjct: 177 RHSPTESGVLAKSASGALELIPYIQITNLADTLGELHKLGFFSVGLDSEGPAPIEQTFTG 236
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K AL LG+E +GL +K + + + M + SLNVS AA I +
Sbjct: 237 AKIALVLGAEGKGLRQKTRETVSALARLDMPGEIKSLNVSNAAAIAL 283
>ref|NP_221026.1| (NC_000963) unknown [Rickettsia prowazekii]
pir||D71672 hypothetical protein RP664 - Rickettsia prowazekii
emb|CAA15102.1| (AJ235272) unknown [Rickettsia prowazekii]
Length = 248
Score = 82.4 bits (202), Expect = 3e-15
Identities = 63/231 (27%), Positives = 109/231 (46%), Gaps = 13/231 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKE---IDKKLFFALKKACPNIIKVDNKKAQSLAKGG 61
+YGK ++ +N+ + +++ I +KE I+KKL V+N L K
Sbjct: 20 MYGKHPVLSAINNPKRQIENILCTKEFFDINKKLIGTRSYEI-----VNNYILSKLLKHQ 74
Query: 62 NHQGVLAKVELPLAVSLKEV---KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
HQG+ AKV + +L ++ K K+++L ITD NIG I RSA + +IL
Sbjct: 75 THQGIAAKVRPIFSYNLDDIDINKPQCKIVILDQITDTQNIGAIIRSAAAFYINAIILPQ 134
Query: 119 AKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI-ENLSL 176
G I +++ G + +P + N +N LK GF +G + + L
Sbjct: 135 DNSPNESGSIAKAACGTLELIPIIKVTNLCSYMNYLKKRGFWIIGVTGYAKEYFTDKLIS 194
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
K AL G+E +G+ + + D + + + + +SLNV+ AA I+ ++
Sbjct: 195 DKIALVFGAEDKGMRRLVKETCDYLAKIPISKSVESLNVANAASIIFHSLH 245
>ref|NP_563340.1| (NC_003366) probable tRNA/rRNA methyltransferase [Clostridium
perfringens]
dbj|BAB82130.1| (AP003194) probable tRNA/rRNA methyltransferase [Clostridium
perfringens]
Length = 289
Score = 82.0 bits (201), Expect = 5e-15
Identities = 61/237 (25%), Positives = 119/237 (49%), Gaps = 16/237 (6%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSK-----EIDKKLFFALKKACPNIIKVDNKKAQSLA 58
++ G+ ++ LL S + +++I+++ I+K L A +K + +VD KK ++
Sbjct: 48 LVEGRNAVIELLKS-DKTIEQIFIANGKMEGSINKILGLAKEKKIV-VKEVDRKKLDLMS 105
Query: 59 KGGNHQGVLAKVELPLAVSLKEVKKAQK-------LLVLCGITDVGNIGGIFRSAYCLGM 111
+ HQGV+A++ +++++ K +++L + D N+G I R+A G
Sbjct: 106 ETKAHQGVIAQITPFKYSTVEDILDLAKSKNEDPFIVILDELEDPHNLGSIVRTAELCGA 165
Query: 112 GGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQ 170
G+I+ + + G V ++S+G + + + + N + I ELK + GA + G
Sbjct: 166 HGIIIPKRRNVGVTGTVYKASVGAIEHMKIAKVTNINNAIEELKANNVWIYGADIAGEEY 225
Query: 171 IENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ K C + +GSE G+S K D ++ + M +SLN SVA GI+M ++
Sbjct: 226 SYETNFKGACGIIIGSEGRGMSNLTKKKCDKLVKIPMVGKINSLNASVAGGIMMYEV 282
>ref|NP_420052.1| (NC_002696) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
gb|AAK23220.1| (AE005799) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
Length = 278
Score = 80.9 bits (198), Expect = 1e-14
Identities = 61/214 (28%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Query: 14 LLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELP 73
L N + + + + + K+L L+K + + A+ L +G HQG+ K++ P
Sbjct: 51 LANPRRPAPKRLLATPDRAKRLAPHLQKLTCLQVMEGQEIAKQLPQGAVHQGLALKIDEP 110
Query: 74 LAVSLKEVKKAQK--LLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RS 130
+++ E+ K L++L ITD NIG IFRSA G GVIL A G++ ++
Sbjct: 111 EPLTIAELGTPAKGFLVMLDQITDPQNIGAIFRSAAAFGAKGVILQDRHAPALSGVLAKT 170
Query: 131 SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN-LSLKKCALFLGSEHEG 189
++G + P++ + N + EL G+ + + + ++ L + L LGSE EG
Sbjct: 171 AVGAVDKAPYARVVNLSRALEELADLGWRAVALAGEAEQSLDAVLDSQPTVLVLGSEGEG 230
Query: 190 LSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ + + D + + M F+SLNVS AA I +
Sbjct: 231 VRRLVAEHCDALGKIPMPGGFESLNVSAAAAIAL 264
>ref|NP_360646.1| (NC_003103) tRNA/rRNA methyltransferase [EC:2.1.1.-] [Rickettsia
conorii]
gb|AAL03547.1| (AE008652) tRNA/rRNA methyltransferase [EC:2.1.1.-] [Rickettsia
conorii]
Length = 240
Score = 80.5 bits (197), Expect = 1e-14
Identities = 62/231 (26%), Positives = 107/231 (45%), Gaps = 13/231 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEI---DKKLFFALKKACPNIIKVDNKKAQSLAKGG 61
+YGK + LN+ + ++ I ++EI +KKL V+N L +
Sbjct: 14 MYGKHPVFSALNNPKRQIDNILCTREIFETNKKLIGTRAYEI-----VNNDILSKLLENQ 68
Query: 62 NHQGVLAKVELPLAVSLKEVKKAQ---KLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
HQG+ AK+ + +L+++ K+ +L ITD NIG I RSA + +IL
Sbjct: 69 THQGIAAKIRPIFSYNLEDIDITNPKCKIAILDQITDTQNIGAIIRSAAAFDINAIILPQ 128
Query: 119 AKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN-LSL 176
G I +++ G + +P + N +N LK GF +G + + N L
Sbjct: 129 DNSPNESGSIAKAACGTLELIPIIKVTNLRSCMNYLKKHGFWIIGLTGSANDYFTNKLIS 188
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
K L GSE +G+ + ++ D + + + + +SLNVS AA I+ ++
Sbjct: 189 DKIVLVFGSEDKGIRRLVVETCDYLAKIPISQRVESLNVSNAASIIFHSLH 239
>ref|NP_539658.1| (NC_003317) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
gb|AAL51922.1| (AE009515) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
Length = 303
Score = 79.0 bits (193), Expect = 4e-14
Identities = 61/221 (27%), Positives = 105/221 (46%), Gaps = 4/221 (1%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGN-- 62
+YG + + + Q K+ + ++ +L + P +++ + + G
Sbjct: 71 LYGLHTVRAAVENPQRKILRMRATRNGFARLEIGEADSLPFPVEIVDPRDIDKETGSEAV 130
Query: 63 HQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKEL 122
HQGV+ + E L E++++ LLVL +TD N+G I RSA G G +I
Sbjct: 131 HQGVMIEAEPLRTRKLSELRESPLLLVLDQVTDPHNVGAIMRSAVAFGAGALITTSHHSP 190
Query: 123 AYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE-NLSLKKCA 180
G++ +++ G + + + N + I EL T GF +G QG ++E LS + A
Sbjct: 191 QETGVLAKAASGALELIAHIEVRNLAEAIEELHTLGFQTIGLDSQGPLEMEATLSGNRIA 250
Query: 181 LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
L LG+E +GL +K + + + M + SLNVS AA I
Sbjct: 251 LVLGAEGKGLRQKTRETVTALARLDMPGEIKSLNVSNAAAI 291
>ref|NP_387977.1| (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
sp|Q06753|YACO_BACSU Hypothetical tRNA/rRNA methyltransferase yacO
pir||S66124 conserved hypothetical protein yacO - Bacillus subtilis
dbj|BAA05329.1| (D26185) unknown [Bacillus subtilis]
emb|CAB11872.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]
Length = 249
Score = 78.2 bits (191), Expect = 7e-14
Identities = 62/235 (26%), Positives = 111/235 (46%), Gaps = 15/235 (6%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDK----KLFFALKKACPNIIKVDNKKAQSLAKG 60
+ GK ++ L S + KL ++++++ K ++ KK I V KK + G
Sbjct: 8 VIGKNAVIETLKSDR-KLYKLWMAENTVKGQAQQVIELAKKQGITIQYVPRKKLDQMVTG 66
Query: 61 GNHQGVLAKVELPLAVSLKEVKKAQK-------LLVLCGITDVGNIGGIFRSAYCLGMGG 113
HQGV+A+V L ++ KA + L+L + D N+G I R+A +G G
Sbjct: 67 -QHQGVVAQVAAYEYAELDDLYKAAEEKNEQPFFLILDELEDPHNLGSIMRTADAVGAHG 125
Query: 114 VILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE 172
+++ + + V ++S G + +P + + N + E+K G +G
Sbjct: 126 IVIPKRRAVGLTTTVAKASTGAIEHIPVARVTNLARTLEEMKERGIWVVGTDASAREDFR 185
Query: 173 NLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
N+ AL +GSE +G+ + + K D ++ + M SLN SVAAG+LM ++
Sbjct: 186 NMDGNMPLALVIGSEGKGMGRLVKEKCDFLIKLPMAGKVTSLNASVAAGLLMYEV 240
>ref|NP_662510.1| (NC_002932) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
gb|AAM72852.1| (AE012917) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
Length = 257
Score = 78.2 bits (191), Expect = 7e-14
Identities = 60/233 (25%), Positives = 110/233 (46%), Gaps = 11/233 (4%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSKEID----KKLFFALKKACPNIIKVDNKKAQSL 57
+ V+YG+ ++ LL S E +++IYL K++ ++ K +K L
Sbjct: 16 EQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLRIPCGKARMEKLTLL 75
Query: 58 AKGGNHQGVLAKVELPLAVSLKEVKKAQK-----LLVLCGITDVGNIGGIFRSAYCLGMG 112
+ +QGV A + +L EV A + L++L G+ D N+G I R+A +
Sbjct: 76 SGTAKNQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAAD 135
Query: 113 GVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
VI+ K V ++S G + + + + + ++ L+ GF + A M+
Sbjct: 136 AVIMIEGKGAPISATVHKASAGALSHMRVCKVKSVVKALDLLRERGFSIVAADMEAEHNH 195
Query: 172 ENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
++ K+ L +G+E GL + + D I+ + M +SLNVSVAAG+++
Sbjct: 196 TDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNVSVAAGVML 248
>ref|NP_104059.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
dbj|BAB49845.1| (AP003000) hypothetical protein [Mesorhizobium loti]
Length = 265
Score = 77.8 bits (190), Expect = 9e-14
Identities = 55/167 (32%), Positives = 89/167 (52%), Gaps = 7/167 (4%)
Query: 63 HQGVLA--KVELPLAVS--LKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD- 117
H+G+LA + P A L + +LVL GI + N+G IFR+A G V++D
Sbjct: 94 HRGILAIGRKATPQAPGPLLDALPDQALVLVLVGIANHDNMGSIFRNAAAFGADAVLMDT 153
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS-L 176
+ Y +R S+G +PF+ +T L GF L S +G + I +
Sbjct: 154 TCCDPLYRKAIRVSVGAALKIPFASFTDTSGFTAMLAERGFEQLALSPRGRTDIRDAKPA 213
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
++ AL+LG+E EGL +++LA++ T+ + M + FDSLNV+ A+ I +
Sbjct: 214 ERLALYLGTEGEGLPERLLARLQTV-RITMSKGFDSLNVAAASAIAL 259
>ref|NP_229539.1| (NC_000853) conserved hypothetical protein [Thermotoga maritima]
pir||D72218 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
gb|AAD36806.1|AE001812_16 (AE001812) conserved hypothetical protein [Thermotoga maritima]
Length = 242
Score = 77.4 bits (189), Expect = 1e-13
Identities = 57/228 (25%), Positives = 115/228 (50%), Gaps = 10/228 (4%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFA--LKKACPNIIKVD---NKKAQSLAK 59
+YG++++ L ++ +++++ K + +F +K+ IK ++ ++L+
Sbjct: 3 VYGRKILEEALRNNVP-IKKVFFQKMKNPGSYFLSLVKEVEKRGIKYSFESEERLKNLSG 61
Query: 60 GGNHQGVLAKVELPLAVSLKEVKKAQK---LLVLCGITDVGNIGGIFRSAYCLGMGGVIL 116
HQGV+ + S++E+ +A+ +++L I D N+G I R++ G G+I+
Sbjct: 62 TKKHQGVVFDIGEYRYSSVEEILEAKTPPLIVLLDQIQDPHNLGAIVRTSVGAGANGIII 121
Query: 117 DFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS 175
K + E +V+ S G ++ +V+ N I ELK G + + G+ E
Sbjct: 122 PKDKSVKVTETVVKVSAGTVFRARIAVVTNLARTIEELKEKGVWTYASDIDGTPIYEEDF 181
Query: 176 LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
A G+E EG+ + + K D ++++ M D DSLNVSV+ G+++
Sbjct: 182 TFPTAFVFGNEGEGIRRLVREKCDRVVTIPMENDIDSLNVSVSVGVVL 229
>ref|NP_371055.1| (NC_002758) hypothetical protein [Staphylococcus aureus subsp.
aureus Mu50]
ref|NP_373742.1| (NC_002745) hypothetical protein, similar to tRNA/rRNA
methyltransferase [Staphylococcus aureus subsp. aureus
N315]
ref|NP_645304.1| (NC_003923) ORFID:MW0487~hypothetical protein, similar to tRNA/rRNA
methyltransferase [Staphylococcus aureus subsp. aureus
MW2]
dbj|BAB41720.1| (AP003130) ORFID:SA0490~hypothetical protein, similar to tRNA/rRNA
methyltransferase [Staphylococcus aureus subsp. aureus
N315]
dbj|BAB56693.1| (AP003359) hypothetical protein [Staphylococcus aureus subsp.
aureus Mu50]
dbj|BAB94352.1| (AP004823) ORFID:MW0487~hypothetical protein, similar to tRNA/rRNA
methyltransferase [Staphylococcus aureus subsp. aureus
MW2]
Length = 248
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/236 (25%), Positives = 109/236 (45%), Gaps = 15/236 (6%)
Query: 4 VIYGKQVIMH-LLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAK 59
VI G+ + ++ H + +I + + I K+ + K + I++ K
Sbjct: 5 VIVGRHAVREAIITGHP--INKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLA 62
Query: 60 GGNHQGVLAKVELPLAVSLKEVKKAQK-------LLVLCGITDVGNIGGIFRSAYCLGMG 112
HQGV A + + K QK +L+L G+ D N+G I R+A G+
Sbjct: 63 NAPHQGVAALIAPYEYADFDQFLKQQKEKEGLSTVLILDGLEDPHNLGSILRTADATGVD 122
Query: 113 GVILDFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
GVI+ + + + + ++S G + +P + N I+ELK +GF G ++
Sbjct: 123 GVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDY 182
Query: 172 ENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
NL A+ +GSE +G+S+ + K D + + M +SLN SVAA ++M ++
Sbjct: 183 RNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
>ref|NP_385444.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
emb|CAC45917.1| (AL591787) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
Length = 291
Score = 77.0 bits (188), Expect = 1e-13
Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 4/226 (1%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIK--VDNKKAQSLAK 59
Q ++YG + L++ + ++ + +++ +L A P + + + + L
Sbjct: 57 QVLLYGLHTVRAALDNPERRIIRLSVTQNAAARLDLGDLTALPFPTETVMPQELDRILGP 116
Query: 60 GGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFA 119
HQGV+ + + L+ ++ +LVL +TD N+G I RSA G +I
Sbjct: 117 DAIHQGVMLETQPLPHRKLEALRDCPLILVLDQVTDPHNVGAIMRSAVAFDAGALITTMR 176
Query: 120 KELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE-NLSLK 177
G++ +S+ G + +P+ + N D + EL GF+ +G +G +E +
Sbjct: 177 HSPTESGVLAKSASGALELIPYIQITNLADTLEELHELGFMTIGLDSEGPQPLEGTFAGD 236
Query: 178 KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K AL LGSE +GL +K + + + M SLNVS AA I M
Sbjct: 237 KIALVLGSEGKGLRQKTRQTVKALARLDMPGAIKSLNVSNAAAIAM 282
>gb|AAK15305.1|AF327733_2 (AF327733) YacO [Staphylococcus aureus]
Length = 248
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/236 (25%), Positives = 109/236 (45%), Gaps = 15/236 (6%)
Query: 4 VIYGKQVIMH-LLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAK 59
VI G+ + ++ H + +I + + I K+ + K + I++ K
Sbjct: 5 VIVGRHAVREAIITGHP--INKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLA 62
Query: 60 GGNHQGVLAKVELPLAVSLKEVKKAQK-------LLVLCGITDVGNIGGIFRSAYCLGMG 112
HQGV A + + K QK +L+L G+ D N+G I R+A G+
Sbjct: 63 NAPHQGVAALIAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVD 122
Query: 113 GVILDFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
GVI+ + + + + ++S G + +P + N I+ELK +GF G ++
Sbjct: 123 GVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDY 182
Query: 172 ENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
NL A+ +GSE +G+S+ + K D + + M +SLN SVAA ++M ++
Sbjct: 183 RNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEV 238
>ref|NP_348974.1| (NC_003030) RRNA methylase, YSGA B.subtilis ortholog [Clostridium
acetobutylicum]
gb|AAK80314.1|AE007736_4 (AE007736) RRNA methylase, YSGA B.subtilis ortholog [Clostridium
acetobutylicum]
Length = 261
Score = 76.6 bits (187), Expect = 2e-13
Identities = 67/231 (29%), Positives = 115/231 (49%), Gaps = 20/231 (8%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLS-KEIDKKLFFALKKACPN---IIKVDNKKAQSLAK 59
++ G + + L S K+Q +++S K DK + LK+ +IKV + +
Sbjct: 32 IVEGLRFVREALES-DFKIQYLFVSEKNYDKFILKELKELIKKEFQVIKVTESILKDICN 90
Query: 60 GGNHQGVLAKVELPLAVSLKEVKKAQKL-----LVLCGITDVGNIGGIFRSAYCLGMGGV 114
QG++A V+ KEV A KL +++ + D GN+G I R+A G GV
Sbjct: 91 TQTPQGIVAVVQY------KEV--AWKLTKGFYMLVDKVQDPGNMGTIIRTANAAGALGV 142
Query: 115 ILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ Y +R+++G ++ +P + I ELK +GF + +S+ +
Sbjct: 143 IITKGTVDIYNNKTLRATMGSIFKIPIIFEDDNFSKIKELKKNGFKIIASSLDTEHNFYD 202
Query: 174 LSL-KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+SL +K + +G+E G+S KI+ DT + + M + +SLNV VAA I+M
Sbjct: 203 VSLNEKLIIAVGNEGNGISDKIVDISDTKVKIPMPGNVESLNVGVAAAIMM 253
>ref|NP_421117.1| (NC_002696) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
gb|AAK24285.1| (AE005901) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
Length = 268
Score = 75.9 bits (185), Expect = 3e-13
Identities = 51/167 (30%), Positives = 87/167 (51%), Gaps = 7/167 (4%)
Query: 63 HQGVLAKVELPLAVSLKEVKKA----QKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDF 118
H+G+LA P AV+ +++ + +LVLCGI + N+GGI+R+A G ++LD
Sbjct: 95 HRGILAVGRKPPAVAARDLLASLPARAMVLVLCGIANHDNMGGIYRNAAAFGADAIVLDA 154
Query: 119 -AKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS-L 176
+ Y +R S+G + +P + + + + L +GF L S + L
Sbjct: 155 DCCDPLYRKAIRVSVGAVLSVPTARLSRDESIADLLDATGFEGLALSPSADEILATLKPA 214
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ A+ LG+E GLS ++A+ I + M FDSLNV+ +GI++
Sbjct: 215 ARTAVLLGTEGPGLSPDVMARARRI-GIPMANSFDSLNVATTSGIVL 260
>ref|NP_404029.1| (NC_003143) putative methylase [Yersinia pestis]
emb|CAC89240.1| (AJ414142) putative methylase [Yersinia pestis]
Length = 246
Score = 75.9 bits (185), Expect = 3e-13
Identities = 63/241 (26%), Positives = 112/241 (46%), Gaps = 18/241 (7%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLF---FALKKACPNIIKVDNKK-AQS 56
M +IYG + LL ++ E+++ K D + A +A +I+V +++ S
Sbjct: 1 MSEIIYGIHAVKALLERDPQRFLEVFILKGRDDRRLQPLIAELEAAGLVIQVASRQWLDS 60
Query: 57 LAKGGNHQGVLAKV---------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAY 107
+GG HQG++A+V +LP +L E + LLVL G+TD N+G RSA
Sbjct: 61 QVEGGVHQGIVARVREGRQYQENDLP---ALLESVETPFLLVLDGVTDPHNLGACLRSAD 117
Query: 108 CLGMGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQ 166
G+ VI+ + I + + G ++P + N + L+ +G + +
Sbjct: 118 AAGVHAVIVPRDRSAQLNAIAKKVASGAAENVPLIKVTNLARTLRVLQEHNVWIVGTAGE 177
Query: 167 GSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDK 225
+ + AL +G+E EG+ + D ++S+ M SLNVSVA G+ + +
Sbjct: 178 ADHTLYQSKMTGPMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFE 237
Query: 226 I 226
+
Sbjct: 238 V 238
>ref|NP_469618.1| (NC_003212) similar to conserved hypothetical proteins like to B.
subtilis YacO protein [Listeria innocua]
ref|NP_463772.1| (NC_003210) similar to conserved hypothetical proteins like to B.
subtilis YacO protein [Listeria monocytogenes EGD-e]
emb|CAD00768.1| (AL591974) similar to conserved hypothetical proteins like to B.
subtilis YacO protein [Listeria monocytogenes]
emb|CAC95506.1| (AL596164) similar to conserved hypothetical proteins like to B.
subtilis YacO protein [Listeria innocua]
Length = 251
Score = 75.5 bits (184), Expect = 4e-13
Identities = 61/238 (25%), Positives = 116/238 (48%), Gaps = 15/238 (6%)
Query: 2 QAVIYGKQVIMHLLNSHQEKLQEIYLS----KEIDKKLFFALKKACPNIIKVDNKKAQSL 57
Q I G+ ++ +L S ++ + +IY+ K + K++ K+ + V +K + +
Sbjct: 7 QEWIGGRNPVLEVLRSDRD-IHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKV 65
Query: 58 AKGGNHQGVLAKVELPLAVSLKEVKKAQK-------LLVLCGITDVGNIGGIFRSAYCLG 110
G HQGV A+V L ++ A + ++L + D N+G I R+A +G
Sbjct: 66 VSGA-HQGVAAQVAAYQYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTADSVG 124
Query: 111 MGGVILDFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS 169
G+I+ + + + + ++S G M +P + N + + EL+ G G +GSS
Sbjct: 125 AHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTDAKGSS 184
Query: 170 QIENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ + A+ +GSE G+S+ + K D ++ + MR SLN SVAA +L+ ++
Sbjct: 185 DYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
>ref|NP_246892.1| (NC_002663) unknown [Pasteurella multocida]
gb|AAK04037.1| (AE006232) unknown [Pasteurella multocida]
Length = 245
Score = 75.1 bits (183), Expect = 6e-13
Identities = 67/239 (28%), Positives = 109/239 (45%), Gaps = 13/239 (5%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKK----LFFALKKACPNIIKVDNKKAQS 56
M IYG + LN+ E+L E+Y K D K L L + I V+ +
Sbjct: 1 MSENIYGIHAVSAFLNNAPERLIEVYALKGRDDKRLQPLLNELHRLGITIQFVNRQTLDK 60
Query: 57 LAKGGNHQGVLAKVELPLAVS------LKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLG 110
A+G HQG++A+V+ ++ L + + LLVL G+TD N+G R+A G
Sbjct: 61 KAEGEVHQGIMARVQPAKELNEADLDTLLQNQSNPLLLVLDGVTDPHNLGACLRTADAAG 120
Query: 111 MGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTS-GFLCLGASMQGS 168
+ VI+ K I R + G +P + N + EL+ +G + + +
Sbjct: 121 VCAVIVPKDKSAQLTAIARKVACGAAEVVPLIRVTNLARTLRELQQKHNIWVVGTAGEAT 180
Query: 169 SQIENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ + L AL +G+E EG+ + D ++S+ M SLNVSVA G+ + +I
Sbjct: 181 NTLYQTQLTGGLALVMGAEGEGMRRLTREHCDQLISIPMAGSVSSLNVSVATGVCLFEI 239
>ref|NP_463230.1| (NC_003197) putative tRNA/rRNA methyltransferase [Salmonella
typhimurium LT2]
gb|AAL23189.1| (AE008905) putative tRNA/rRNA methyltransferase [Salmonella
typhimurium LT2]
Length = 243
Score = 74.7 bits (182), Expect = 7e-13
Identities = 61/238 (25%), Positives = 108/238 (44%), Gaps = 18/238 (7%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKK-AQS 56
M +IYG + LL E+ QE+++ K + K L A + +I++ N++
Sbjct: 1 MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDE 60
Query: 57 LAKGGNHQGVLAKV---------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAY 107
+ G HQG++A+V +LP ++L + LL+L G+TD N+G RSA
Sbjct: 61 KSDGAVHQGIIARVKPGRQYQENDLPDLIALHD---RPFLLILDGVTDPHNLGACLRSAD 117
Query: 108 CLGMGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQ 166
G+ VI+ + + + G +P + N + L+ +G + +
Sbjct: 118 AAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGE 177
Query: 167 GSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ + + AL +G+E EG+ + D ++S+ M SLNVSVA GI +
Sbjct: 178 ADHTLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
>ref|NP_214299.1| (NC_000918) rRNA methylase [Aquifex aeolicus]
pir||A70463 rRNA methylase - Aquifex aeolicus
gb|AAC07690.1| (AE000761) rRNA methylase [Aquifex aeolicus]
Length = 240
Score = 74.7 bits (182), Expect = 7e-13
Identities = 68/230 (29%), Positives = 115/230 (49%), Gaps = 13/230 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEID--KKLFFALKKACPNIIKVDNKKAQSLAKGG 61
VI+G+ I+ L + + L++IY++ + K+L KK + ++ KK + LA
Sbjct: 6 VIWGRNPIIEALRAGRN-LEKIYVAHDSHPPKELLELAKKRGVKVQRISRKKVEELAGTK 64
Query: 62 NHQGVLAKVELPLAVSLKE-----VKKAQKLLVLCGITDVGNIGGIFRSAYCLG-MGGVI 115
QGV+A + VS E ++K +V+ ITD N+G + R+ LG +G +I
Sbjct: 65 KTQGVVALLSPVNYVSPHELFKECIEKKSFFIVIDHITDPQNVGNLLRTCEVLGGVGALI 124
Query: 116 LDFAKELAYEGIVRSSLGLMYDLPFSVMPN-TLDLINELKTSGFLCLGASMQGSSQIENL 174
E +V++S G ++ L S + + + +L N K G++ A +G I +
Sbjct: 125 SKDRTSPINETVVKASSGAVFHLKISKVSSLSRELKNFQKMGGWVF--AVEKGGKDIREV 182
Query: 175 SLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ AL LGSE +G+SK +L D I+++ M+ SLNV A I M
Sbjct: 183 DIPLPVALVLGSEDKGVSKSVLDISDQIVTIPMKGKVTSLNVGSAGAIAM 232
>ref|NP_441742.1| (NC_000911) hypothetical protein [Synechocystis sp. PCC 6803]
sp|P74328|Y955_SYNY3 Hypothetical tRNA/rRNA methyltransferase SLR0955
pir||S76163 hypothetical protein - Synechocystis sp. (strain PCC 6803)
dbj|BAA18422.1| (D90914) ORF_ID:slr0955~hypothetical protein [Synechocystis sp. PCC
6803]
Length = 384
Score = 74.3 bits (181), Expect = 9e-13
Identities = 62/237 (26%), Positives = 110/237 (46%), Gaps = 15/237 (6%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALK----KACPNII-KVDNKKAQSLA 58
++YG ++ L+ ++ L I+++ + + + K KA ++ +VDN + +
Sbjct: 125 LLYGHHAVLAALDGDRQ-LNRIWITSHLRHDIRYRTKIQTAKANGTVVDEVDNFRLNQIT 183
Query: 59 KGGNHQGVLAKV------EL-PLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGM 111
NHQG+ A+V EL L K A L+++ ITD N+G I R+A G
Sbjct: 184 HNANHQGIAAQVAPYHYWELGDLIDKAKSQSTAPVLIIIDSITDPHNLGAIIRTAEAFGA 243
Query: 112 GGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQ 170
G++L + +++ + G + P + + N + LK SGF G +
Sbjct: 244 QGMVLPQRRVAGITSTVMKVAAGALEHFPVARVVNLSRALETLKESGFWIYGTVAGKQTA 303
Query: 171 IENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ L++ L +GSE EGLS D ++++ + SLN SVAA I + +I
Sbjct: 304 LHQADLREPMGLVIGSEGEGLSLLTQKHCDHLITIPLAGKTPSLNASVAAAISLYEI 360
>ref|NP_562805.1| (NC_003366) probable rRNA methylase [Clostridium perfringens]
dbj|BAB81595.1| (AP003192) probable rRNA methylase [Clostridium perfringens]
Length = 257
Score = 73.9 bits (180), Expect = 1e-12
Identities = 51/198 (25%), Positives = 106/198 (52%), Gaps = 10/198 (5%)
Query: 29 KEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLL 88
KE + LF + + +I+++ + L N QG++ + + KE+K + ++
Sbjct: 58 KEKNPDLFLKINENI-KLIQMNEALLKQLCSTENPQGIVGVINM----QNKELKSGELVV 112
Query: 89 VLCGITDVGNIGGIFRSAYCLGMGGVILDFAK-ELAYEGIVRSSLGLMYDLPFSVMPNTL 147
++ + D GN+G I R+A+ G G+++ ++ + +RS++G ++ +P V ++L
Sbjct: 113 LVDKVQDPGNMGTIIRTAHAAGAAGIVMTKGTVDIYNDKTLRSTMGSIFYIPI-VEDDSL 171
Query: 148 DLINELKTSGFLCLGASMQGSSQI--ENLSLKKCALFLGSEHEGLSKKILAKMDTILSVK 205
D + LK G+ + +S+QG + ENL K + +G+E G+S ++ D + +
Sbjct: 172 DFVKSLKKEGYKLVVSSLQGKNNFFEENLQ-GKVMIAVGNEGNGVSDEVYDIADIKVKIP 230
Query: 206 MRRDFDSLNVSVAAGILM 223
M + +SLNV+VA I++
Sbjct: 231 MPGEAESLNVAVATSIMI 248
>ref|NP_625830.1| (NC_003888) putative rRNA methylase [Streptomyces coelicolor A3(2)]
emb|CAB76071.1| (AL157953) putative rRNA methylase [Streptomyces coelicolor A3(2)]
Length = 272
Score = 73.6 bits (179), Expect = 2e-12
Identities = 54/180 (30%), Positives = 93/180 (51%), Gaps = 8/180 (4%)
Query: 49 VDNKKAQSLAKGGNHQGVLAKVEL-PLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAY 107
VD A+ + H+G LA ++ PL + + A++++V+ + D NIG IFRSA
Sbjct: 82 VDPALAERVTGYHVHRGALASMQRKPLDTAAGLLTTARRVVVMESVNDHTNIGAIFRSAA 141
Query: 108 CLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASM 165
LGM ++L D A L Y V+ S+G ++ +P++ + + + +GF L +
Sbjct: 142 ALGMDAILLSPDCADPL-YRRSVKVSMGAVFSVPYARLDTWPAGLAAVGEAGFTLLALTP 200
Query: 166 QGSSQ----IENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
++ + + + AL LG+E GL+++ LA DT + + M DSLNV AA +
Sbjct: 201 DERAEPLDAVAPHRMDRVALMLGAEGSGLTRRALAASDTWVRIPMSHGVDSLNVGAAAAV 260
>ref|NP_458805.1| (NC_003198) probable tRNA/rRNA methyltransferase [Salmonella
enterica subsp. enterica serovar Typhi]
emb|CAD06846.1| (AL627283) probable tRNA/rRNA methyltransferase [Salmonella
enterica subsp. enterica serovar Typhi]
Length = 243
Score = 73.2 bits (178), Expect = 2e-12
Identities = 61/238 (25%), Positives = 107/238 (44%), Gaps = 18/238 (7%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKK-AQS 56
M +IYG + LL E+ QE ++ K + K L A + +I++ N++
Sbjct: 1 MSEMIYGIHAVQALLERAPERFQEAFILKGREDKRLLPLIHALESQGVVIQLANRQYLDE 60
Query: 57 LAKGGNHQGVLAKV---------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAY 107
+ G HQG++A+V +LP ++L + LL+L G+TD N+G RSA
Sbjct: 61 KSDGAVHQGIIARVKPGRQYQENDLPDLIALHD---RPFLLILDGVTDPHNLGACLRSAD 117
Query: 108 CLGMGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQ 166
G+ VI+ + + + G +P + N + L+ +G + +
Sbjct: 118 AAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGE 177
Query: 167 GSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ + + AL +G+E EG+ + D ++S+ M SLNVSVA GI +
Sbjct: 178 ADHTLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
>ref|NP_290810.1| (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
ref|NP_313183.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
ref|NP_418601.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
sp|P39290|YJFH_ECOLI Hypothetical tRNA/rRNA methyltransferase yjfH
pir||S56405 hypothetical 26.6K protein (vacB-aidB intergenic region) -
Escherichia coli
gb|AAA97076.1| (U14003) ORF_o243 [Escherichia coli]
gb|AAC77137.1| (AE000490) orf, hypothetical protein [Escherichia coli K12]
gb|AAG59376.1|AE005651_5 (AE005651) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
dbj|BAB38579.1| (AP002568) hypothetical protein [Escherichia coli O157:H7]
Length = 243
Score = 73.2 bits (178), Expect = 2e-12
Identities = 63/239 (26%), Positives = 108/239 (44%), Gaps = 20/239 (8%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKK-AQS 56
M +IYG + LL E+ QE+++ K + K L A + +I++ N++
Sbjct: 1 MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDE 60
Query: 57 LAKGGNHQGVLAKV---------ELP-LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSA 106
+ G HQG++A+V +LP L SL + LL+L G+TD N+G RSA
Sbjct: 61 KSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQ----PFLLILDGVTDPHNLGACLRSA 116
Query: 107 YCLGMGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASM 165
G+ VI+ + + + G +P + N + L+ +G +
Sbjct: 117 DAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAG 176
Query: 166 QGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ + + + AL +G+E EG+ + D ++S+ M SLNVSVA GI +
Sbjct: 177 EADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICL 235
>ref|NP_539346.1| (NC_003317) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
gb|AAL51610.1| (AE009486) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
Length = 276
Score = 72.4 bits (176), Expect = 4e-12
Identities = 54/172 (31%), Positives = 92/172 (53%), Gaps = 9/172 (5%)
Query: 63 HQGVLA----KVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD- 117
H+G+LA K + L L + + ++VLCGI++ N+G IFR+A V++D
Sbjct: 104 HRGILAVGRRKSQPDLRDMLAALPQKSLVVVLCGISNHDNVGSIFRNAAAFEADCVLMDE 163
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLIN-ELKTSGFLCLGASMQGSSQIENLSL 176
+ Y +R S+G +P+ T+D IN L +GF L + I ++
Sbjct: 164 TCCDPLYRKAIRVSVGAALKVPY-FHGGTIDDINAALAEAGFNLLALTPSAPRSIYEATI 222
Query: 177 -KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKIN 227
++ AL LG+E EGL ++L +++T + M + FDSLNV+ A+GI + + +
Sbjct: 223 CERQALLLGTEGEGLPSRLLERLET-ARIPMSKTFDSLNVATASGIALSRFS 273
>ref|NP_439020.1| (NC_000907) conserved hypothetical protein [Haemophilus influenzae
Rd]
sp|P44906|YJFH_HAEIN Probable tRNA/rRNA methyltransferase HI0860
pir||E64160 hypothetical protein HI0860 - Haemophilus influenzae (strain Rd
KW20)
gb|AAC22519.1| (U32767) conserved hypothetical protein [Haemophilus influenzae Rd]
Length = 246
Score = 72.4 bits (176), Expect = 4e-12
Identities = 68/239 (28%), Positives = 110/239 (45%), Gaps = 13/239 (5%)
Query: 1 MQAVIYGKQVIMHLLNSHQEKLQEIYLSK-EIDKKLFFALKKACPNIIKVDNKKAQSLAK 59
M IYG + +L E+L E+++ K DK+L L + I V Q+L K
Sbjct: 1 MSEQIYGIHAVNSILTHSPERLIEVFVLKGREDKRLQPLLNELYSLGIGVQFVNRQTLDK 60
Query: 60 ---GGNHQGVLAKVELPLAVSLKEV------KKAQKLLVLCGITDVGNIGGIFRSAYCLG 110
G HQGV+A+V+ ++ ++ K+ LLVL G+TD N+G R+A G
Sbjct: 61 KADGEVHQGVIARVQAAKELNENDLDEILANKQNPLLLVLDGVTDPHNLGACLRTADAAG 120
Query: 111 MGGVILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTS-GFLCLGASMQGS 168
VI+ K I R + G +P + N + +L+ + +G + + +
Sbjct: 121 AVAVIVPKDKSAQLTSIARKVACGAAETVPLIRVTNLSRTLRDLQQNHNIWVVGTAGEAT 180
Query: 169 SQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
I L AL +G+E EG+ + D ++S+ M SLNVSVA G+ + +I
Sbjct: 181 ETIYQSKLTGPLALVMGAEGEGMRRLTREHCDQLISIPMAGSVSSLNVSVATGVCLFEI 239
>ref|NP_102094.1| (NC_002678) tRNA/rRNA metyltransferase [Mesorhizobium loti]
dbj|BAB47880.1| (AP002994) tRNA/rRNA metyltransferase [Mesorhizobium loti]
Length = 235
Score = 72.0 bits (175), Expect = 5e-12
Identities = 57/223 (25%), Positives = 107/223 (47%), Gaps = 8/223 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAK----G 60
+YG + L++ + K++++ +++ ++L ++ K + + + + K
Sbjct: 3 LYGLHTVRAALDNPRRKIRKMLVTRNAAERL--EIEDLAALTFKAELVEPRDIDKITGSD 60
Query: 61 GNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAK 120
HQGVL + E L + + +LVL ITD N+G I RSA G G +I
Sbjct: 61 AVHQGVLIEAEPLKPKRLDALGDTRLVLVLDQITDPHNVGAILRSAVAFGAGALITTARH 120
Query: 121 ELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE-NLSLKK 178
G++ +S+ G + + + N D + +L +GF +G G +++E + + +
Sbjct: 121 SPQESGVLAKSASGALEHIDQIEVKNLADALGQLHEAGFQTIGLDSDGPAELETSFAGDR 180
Query: 179 CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
AL LG+E +GL +K + T+ + M SLNVS AA +
Sbjct: 181 IALVLGAEGKGLRQKTRETVTTLARLDMPGAIRSLNVSNAAAV 223
>ref|NP_218549.1| (NC_000919) rRNA methylase, putative [Treponema pallidum]
pir||D71364 probable rRNA methylase - syphilis spirochete
gb|AAC65100.1| (AE001196) rRNA methylase, putative [Treponema pallidum]
Length = 292
Score = 71.2 bits (173), Expect = 8e-12
Identities = 52/141 (36%), Positives = 72/141 (50%), Gaps = 1/141 (0%)
Query: 87 LLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELA-YEGIVRSSLGLMYDLPFSVMPN 145
+LVL ITD N+G I RSA + V+L E I R S G + +P + N
Sbjct: 133 VLVLDAITDPHNVGAIVRSADQFSVDAVLLPHHHGAGGTETITRVSAGAVAWVPLVRVRN 192
Query: 146 TLDLINELKTSGFLCLGASMQGSSQIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVK 205
+ LK SGF GA + G + K AL LG+E G+S + D ++S+
Sbjct: 193 LVRTAGILKRSGFWLYGADVAGEAIGARTFPPKTALVLGNEGHGVSPLLRTHCDALISIP 252
Query: 206 MRRDFDSLNVSVAAGILMDKI 226
+ + DSLNVSVAAGIL+ +I
Sbjct: 253 TQGNVDSLNVSVAAGILLYEI 273
>ref|NP_240979.1| (NC_002570) tRNA/rRNA methyltransferase [Bacillus halodurans]
dbj|BAB03832.1| (AP001507) tRNA/rRNA methyltransferase [Bacillus halodurans]
Length = 249
Score = 71.2 bits (173), Expect = 8e-12
Identities = 63/232 (27%), Positives = 108/232 (46%), Gaps = 14/232 (6%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDK----KLFFALKKACPNIIKVDNKKAQSLAKG 60
I GK I+ L S + + +I++ + K K+ K+ + V +K L
Sbjct: 6 ITGKNPIIEALRSGRP-MNKIWIGEGSQKGQMQKVLELAKEQGVLVQHVPKRKLDQLIGH 64
Query: 61 GNHQGVLAKVELPLAVSLKEV--KKAQK-----LLVLCGITDVGNIGGIFRSAYCLGMGG 113
NHQGV+A V + ++ + A+K +VL + D N+G I R+A G+ G
Sbjct: 65 ENHQGVVASVAAYEYAEMDDLFQRAAEKGEEPFFIVLDEVEDPHNLGSILRTADAAGVHG 124
Query: 114 VILDFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE 172
VI+ + + + + ++S G + +P + N + +LK G +G +GS
Sbjct: 125 VIIPKRRAVGLTQTVAKASTGAIEYVPVVRVTNLARTMEDLKKRGLWFIGTDAKGSEDYR 184
Query: 173 NLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ AL +GSE +GLS+ + K D ++ + M SLN SVA +LM
Sbjct: 185 GAAYDMPIALVIGSEGKGLSRLVREKCDFLVRIPMVGQVTSLNASVATSLLM 236
>ref|NP_253623.1| (NC_002516) probable rRNA methylase [Pseudomonas aeruginosa]
pir||B83030 probable rRNA methylase PA4936 [imported] - Pseudomonas aeruginosa
(strain PAO1)
gb|AAG08321.1|AE004906_9 (AE004906) probable rRNA methylase [Pseudomonas aeruginosa]
Length = 248
Score = 71.2 bits (173), Expect = 8e-12
Identities = 61/234 (26%), Positives = 107/234 (45%), Gaps = 12/234 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSK-EIDKKLFFALKKACPNIIKVDNKKAQSLAKG--G 61
+YG + LL H +++++++L++ D ++ + A I V + + L + G
Sbjct: 7 VYGVHAVEALLRHHPKRVKQLWLAEGRHDPRVQVLTELAAGFRIPVGQRDRRELDEWAEG 66
Query: 62 NHQGVLAKV-------ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
HQGV+A+V E L L+ + LL L G+TD N+G R+A G+ V
Sbjct: 67 VHQGVVAEVSPSQVWGENMLEELLERSEGVPLLLALDGVTDPHNLGACLRTADAAGVQAV 126
Query: 115 ILDFAKELAYEGIVRS-SLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
I+ K VR + G +P + N + +L+ G +G + + +
Sbjct: 127 IVPKDKSATLNATVRKVACGAAEVIPLVAVTNLARTLEKLQQRGLWVVGTAGEADKTLYQ 186
Query: 174 LSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
L LK L +G+E +G+ + D + + M SLNVSVA G+ + +I
Sbjct: 187 LDLKGPTVLVMGAEGKGMRRLTREHCDFLARLPMAGSVSSLNVSVATGVCLFEI 240
>ref|NP_601840.1| (NC_003450) COG0566:rRNA methylases [Corynebacterium glutamicum]
dbj|BAC00034.1| (AP005282) rRNA methylases [Corynebacterium glutamicum ATCC 13032]
Length = 313
Score = 70.1 bits (170), Expect = 2e-11
Identities = 46/191 (24%), Positives = 88/191 (45%), Gaps = 9/191 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVEL-------PLAVSLKEVKKAQKLLVLCGITDVGN 98
+++V+ + + G HQG+ + L + KK ++L ITD N
Sbjct: 116 VLEVNKLELDRMTGNGMHQGIGLAIPPYEYADVHDLIANAAASKKPGMFVILDNITDPRN 175
Query: 99 IGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSG 157
+G + RS G GVI+ + + + R+S G +P + N ++ E + +G
Sbjct: 176 LGAVIRSVGAFGGNGVIIPERRSASVTAVAWRTSAGTAARVPVAKETNMTRVVKEFQQNG 235
Query: 158 FLCLGASMQGSSQIENLS-LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVS 216
+ +G G ++ + +GSE +G+S+ + DTI+S+ +SLN S
Sbjct: 236 YQVVGLDAGGDHTLDTYDGTDNVVIVVGSEGKGISRLVRENCDTIMSIPTEGWVESLNAS 295
Query: 217 VAAGILMDKIN 227
VAAG+++ + +
Sbjct: 296 VAAGVVLSEFS 306
>ref|NP_299267.1| (NC_002488) tRNA/rRNA methyltransferase [Xylella fastidiosa 9a5c]
pir||D82613 tRNA/rRNA methyltransferase XF1985 [imported] - Xylella fastidiosa
(strain 9a5c)
gb|AAF84787.1|AE004018_3 (AE004018) tRNA/rRNA methyltransferase [Xylella fastidiosa 9a5c]
Length = 249
Score = 69.3 bits (168), Expect = 3e-11
Identities = 58/185 (31%), Positives = 85/185 (45%), Gaps = 9/185 (4%)
Query: 48 KVDNKKAQSLAKGGNHQGVLAK---VELPLAVSLKEVKKAQK----LLVLCGITDVGNIG 100
+V + + G HQGV A+ V L LK++ A LLVL G+ D N+G
Sbjct: 55 RVTTQALDGVGGGVRHQGVAARYAAVRLWEEHDLKDLVDAAGGQALLLVLDGVQDPHNLG 114
Query: 101 GIFRSAYCLGMGGVILDFAKELAYEGIVR-SSLGLMYDLPFSVMPNTLDLINELKTSGFL 159
RSA G+ VI+ K + VR +S G LP + N + EL+
Sbjct: 115 ACLRSAAAAGVTAVIIPKDKSVGINATVRKTSSGAADRLPVIAVVNLARSLRELQKQDVW 174
Query: 160 CLGASMQGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVA 218
G + + + L L+ K AL LG E +GL + D + + M + +SLNVSVA
Sbjct: 175 IYGLEGEAETSLYALDLRGKVALVLGGEADGLRRLTREHCDVLARIPMPGEVESLNVSVA 234
Query: 219 AGILM 223
AG+ +
Sbjct: 235 AGVTL 239
>ref|NP_243978.1| (NC_002570) rRNA methylase [Bacillus halodurans]
dbj|BAB06831.1| (AP001517) rRNA methylase [Bacillus halodurans]
Length = 251
Score = 69.3 bits (168), Expect = 3e-11
Identities = 50/181 (27%), Positives = 92/181 (50%), Gaps = 5/181 (2%)
Query: 45 NIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFR 104
++I V ++ L + QG+ A +P S +E++ L + + D GN+G + R
Sbjct: 69 DVILVSDRVMADLTETKTPQGIAAICHIPDEPSFQELEGM--FLCIDHVQDPGNVGTMIR 126
Query: 105 SAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGA 163
+ GM VI+ Y +VR+S G ++ LP + + +++ K +G G
Sbjct: 127 TCDAAGMSAVIVSEGSVDIYNSKVVRASQGSIFHLPV-IKGDLHGWVDQFKEAGIPVFGT 185
Query: 164 SMQGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGIL 222
+++G S + + + AL +G+E EG+ ++L K D L + + +SLNV+VA GIL
Sbjct: 186 ALEGGSTYTAIEPQARFALLVGNEGEGVEPELLDKADQNLYIPLYGKAESLNVAVATGIL 245
Query: 223 M 223
+
Sbjct: 246 L 246
>ref|NP_232226.1| (NC_002505) RNA methyltransferase, TrmH family [Vibrio cholerae]
pir||B82055 RNA methyltransferase, TrmH family VC2598 [imported] - Vibrio
cholerae (group O1 strain N16961)
gb|AAF95739.1| (AE004327) RNA methyltransferase, TrmH family [Vibrio cholerae]
Length = 247
Score = 68.9 bits (167), Expect = 4e-11
Identities = 58/232 (25%), Positives = 104/232 (44%), Gaps = 12/232 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSK-EIDKKLFFALKKACP---NIIKVDNKKAQSLAK 59
+IYG + +L + E Y+ K D +L L + +I ++ K A+
Sbjct: 5 LIYGIHAVNAVLQRDPARFVEAYVLKGRQDDRLLPVLNELMRLGVSIQEMSRKALDDKAE 64
Query: 60 GGNHQGVLAKVELPLAVSLKEVK------KAQKLLVLCGITDVGNIGGIFRSAYCLGMGG 113
G NHQG++A+V+ ++ ++ + LLVL G+TD N+G R+A G+
Sbjct: 65 GANHQGLIARVKPARQLNENDLDDILAQHEQPLLLVLDGVTDPHNLGACLRNADAAGVAA 124
Query: 114 VILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIE 172
VI+ K V + + G +P + N + L+ G +G + + + I
Sbjct: 125 VIVPKDKSAPLTATVSKVACGAAETVPLVRVTNLARTMRALQEKGVWFVGTAGEATHDIY 184
Query: 173 NLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
L A+ +G+E +G+ + D ++ + M SLNVSVA G+ +
Sbjct: 185 QSKLTGSLAIVMGAEGDGMRRLTRETCDDLIKIPMAGSVSSLNVSVACGVCL 236
>ref|NP_071221.1| (NC_000917) rRNA methylase, putative [Archaeoglobus fulgidus]
sp|O30272|YN99_ARCFU Hypothetical tRNA/rRNA methyltransferase AF2399
pir||H69549 rRNA methylase homolog - Archaeoglobus fulgidus
gb|AAB91264.1| (AE001110) rRNA methylase, putative [Archaeoglobus fulgidus]
Length = 224
Score = 68.9 bits (167), Expect = 4e-11
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Query: 87 LLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAY-EGIVRSSLGLMYDLPFSVMPN 145
+L L + D NIG R+A G GV+L + + EG V++S G ++ +P + + N
Sbjct: 79 ILFLDNVVDQRNIGACIRTAEFFGAAGVVLPKRRVGSIQEGAVKASAGAVFHIPIARVEN 138
Query: 146 TLDLINELKTSGFLCLGASMQGSSQIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVK 205
I +LK GF L A + G L A+ +G E G+S+ + + D ++ +
Sbjct: 139 FASAIKKLKKLGFTTLAADLDGEDLEAVSLLLPAAVVIGGEDRGVSRPVKKQCDFVVKIP 198
Query: 206 MRRDFDSLNVSVAAGILM 223
+SLN+SVAAGI +
Sbjct: 199 GVGKVNSLNLSVAAGIFL 216
>gb|EAA02680.1| (AAAB01006210) ebiP448 [Anopheles gambiae str. PEST]
Length = 232
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/172 (29%), Positives = 87/172 (50%), Gaps = 11/172 (6%)
Query: 62 NHQGVLAKV-ELP------LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
NHQGV+A + ++P + L E K +L+L +TDV N G I R+A C+G+ +
Sbjct: 53 NHQGVVAFISDIPFYKIEDVLPQLFEEGKTPFILILDRLTDVRNFGAISRTAECVGVDAI 112
Query: 115 IL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI-- 171
I+ + +++S G +Y++ N ++ L+ SG A+ + I
Sbjct: 113 IIPEKGAAPINSDAIKTSAGALYNVKICKEKNLAHAVDFLQQSGIKVFAATEKAQKLIYE 172
Query: 172 ENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
EN + C + +G+E G+SK++L D + + + SLNVSVA G ++
Sbjct: 173 ENFTEPVC-IVMGNEETGISKEVLHHADEKIKLPIEGKTQSLNVSVACGAIL 223
>ref|NP_658590.1| (NC_003995) SpoU_methylase, SpoU rRNA Methylase family [Bacillus
anthracis A2012] [Bacillus anthracis str. A2012]
Length = 254
Score = 67.8 bits (164), Expect = 9e-11
Identities = 49/139 (35%), Positives = 77/139 (55%), Gaps = 3/139 (2%)
Query: 86 KLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMP 144
K L+L G+ D GN+G I R+A G+ V+L AY ++RS+ G ++ LP V
Sbjct: 106 KFLLLDGLQDPGNLGTIIRTADAAGIHAVVLGEGCVDAYNSKVLRSTQGSIFHLPI-VKG 164
Query: 145 NTLDLINELKTSGFLCLGASMQ-GSSQIENLSLKKCALFLGSEHEGLSKKILAKMDTILS 203
N + +++LK + G +++ G E AL +G+E G+ ++ILAK D L
Sbjct: 165 NLKEWVDKLKENNVPVYGTALENGVPYGEVTPAGSFALIVGNEGNGVRQEILAKTDQNLY 224
Query: 204 VKMRRDFDSLNVSVAAGIL 222
+ + +SLNV+VAAGIL
Sbjct: 225 IPIYGGAESLNVAVAAGIL 243
>ref|NP_326009.1| (NC_002771) TRNA/RRNA METHYLTRANSFERASE [Mycoplasma pulmonis]
emb|CAC13351.1| (AL445563) TRNA/RRNA METHYLTRANSFERASE [Mycoplasma pulmonis]
Length = 229
Score = 67.8 bits (164), Expect = 9e-11
Identities = 55/185 (29%), Positives = 94/185 (50%), Gaps = 8/185 (4%)
Query: 47 IKVDNKKAQ---SLAKGGNHQGVLAKVELPLAVSLKE-VKKAQKLLVLCGITDVGNIGGI 102
IK++ K Q SL K NHQG +A ++ VSL + +K + +L+L + D N G I
Sbjct: 41 IKIEVKDKQFLDSLVKE-NHQGYVAVLKSLNFVSLDQMIKSKETILILDHLEDPYNFGAI 99
Query: 103 FRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
RSA G+ +I + + +++ S G +L F + I++LK G+
Sbjct: 100 LRSANAFGIKNIIYPIKRAVDINSTVLKVSSGGFVNLRFYKSNSISATIDKLKKQGYWIY 159
Query: 162 GASMQGSSQ-IENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
+S+ +S+ I +S L +G+E +G+S+ + D + +K + SLN SVAA
Sbjct: 160 SSSLDPTSEDINKISFNNPSVLVIGNEKKGISQTTKKQSDQLFYIKTKGSVQSLNASVAA 219
Query: 220 GILMD 224
GI+ +
Sbjct: 220 GIIFN 224
>ref|NP_390743.1| (NC_000964) similar to rRNA methylase [Bacillus subtilis]
pir||G69984 rRNA methylase homolog ysgA - Bacillus subtilis
emb|CAA99602.1| (Z75208) hypothetical protein [Bacillus subtilis]
emb|CAB14825.1| (Z99118) similar to rRNA methylase [Bacillus subtilis]
Length = 248
Score = 67.8 bits (164), Expect = 9e-11
Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 3/147 (2%)
Query: 79 KEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYD 137
+++ A+K+L++ + D GN+G + R+A G+ V+L A+ G +RS+ G +
Sbjct: 98 EKLATARKVLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTADAFNGKTLRSAQGSHFH 157
Query: 138 LPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKC-ALFLGSEHEGLSKKILA 196
+P V N ++ELK G G ++Q + + + + AL +G+E G+ +L
Sbjct: 158 IPV-VRRNLPSYVDELKAEGVKVYGTALQNGAPYQEIPQSESFALIVGNEGAGVDAALLE 216
Query: 197 KMDTILSVKMRRDFDSLNVSVAAGILM 223
K D L V + +SLNV+VAA IL+
Sbjct: 217 KTDLNLYVPLYGQAESLNVAVAAAILV 243
>ref|NP_371661.1| (NC_002758) hypothetical protein [Staphylococcus aureus subsp.
aureus Mu50]
ref|NP_374254.1| (NC_002745) hypothetical protein, similar to rRNA methylase
[Staphylococcus aureus subsp. aureus N315]
ref|NP_645837.1| (NC_003923) ORFID:MW1020~hypothetical protein, similar to rRNA
methylase [Staphylococcus aureus subsp. aureus MW2]
dbj|BAB42233.1| (AP003132) ORFID:SA0984~hypothetical protein, similar to rRNA
methylase [Staphylococcus aureus subsp. aureus N315]
dbj|BAB57299.1| (AP003361) hypothetical protein [Staphylococcus aureus subsp.
aureus Mu50]
dbj|BAB94885.1| (AP004825) ORFID:MW1020~hypothetical protein, similar to rRNA
methylase [Staphylococcus aureus subsp. aureus MW2]
Length = 246
Score = 67.8 bits (164), Expect = 9e-11
Identities = 54/181 (29%), Positives = 97/181 (52%), Gaps = 12/181 (6%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRS 105
+ +++ K A+SL+ QG A +E P ++ KAQ++L++ + D GN+G + R+
Sbjct: 70 VFEINMKVAESLSGTVTPQGFFAIIEKPHY----DISKAQQVLLIDRVQDPGNLGTLIRT 125
Query: 106 AYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLD-LINELKTSGFLCLGA 163
A GM VI++ Y+ ++R+S G ++ LP VM LD I + + G
Sbjct: 126 ADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLP--VMTQDLDTFITQFNGPVY---GT 180
Query: 164 SMQGS-SQIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGIL 222
+++ + + E S AL LG+E EG++ ++LA L + + +SLNV++A IL
Sbjct: 181 ALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQNLIIPIYGKAESLNVAIAGSIL 240
Query: 223 M 223
+
Sbjct: 241 L 241
>ref|NP_266763.1| (NC_002662) tRNA/rRNA methyltransferase [Lactococcus lactis subsp.
lactis]
gb|AAK04705.1|AE006293_11 (AE006293) tRNA/rRNA methyltransferase [Lactococcus lactis subsp.
lactis]
Length = 252
Score = 67.4 bits (163), Expect = 1e-10
Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 10/179 (5%)
Query: 49 VDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVK--KAQKLLVLCGITDVGNIGGIFRSA 106
V + +SLA + QG++A+V ++EV A K L+L + D GN+G + R+A
Sbjct: 77 VSKEVLKSLADSESPQGLIAEV-----TKIEEVIDFSAAKFLLLENVQDPGNVGTMIRTA 131
Query: 107 YCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASM 165
G VIL ++ ++RS G + LP M D +LK +G L ++
Sbjct: 132 DAAGFSAVILLGETADIYSPKVMRSMQGSNFHLPLVRMAKE-DCFAQLKKAGISILTTTL 190
Query: 166 QGSS-QIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+S + ++ AL +G+E G+S + + D ++ + M +SLNV+VAAGILM
Sbjct: 191 SANSVSYKIINEPHFALIMGNEGAGVSDEAVKAADKLVHIDMPGQAESLNVAVAAGILM 249
>ref|NP_602346.1| (NC_003454) 23S rRNA methyltransferase [Fusobacterium nucleatum
subsp. nucleatum ATCC 25586]
gb|AAL93645.1| (AE010460) 23S rRNA methyltransferase [Fusobacterium nucleatum
subsp. nucleatum ATCC 25586]
Length = 234
Score = 67.4 bits (163), Expect = 1e-10
Identities = 48/147 (32%), Positives = 75/147 (50%), Gaps = 2/147 (1%)
Query: 82 KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAY-EGIVRSSLGLMYDLPF 140
K +L+L I D N G I RSA + +I+ + E +V++S G + +
Sbjct: 85 KDKSLVLILDEIQDPRNFGAIIRSAEVFKVDLIIIPERNSVRINETVVKTSTGAIEYVNI 144
Query: 141 SVMPNTLDLINELKTSGFLCLGASMQGS-SQIENLSLKKCALFLGSEHEGLSKKILAKMD 199
S + N D IN+LK + GA+ + + S E K L LG+E G+ KK+ D
Sbjct: 145 SKVTNLSDTINKLKKLDYWVYGAAGEANISYNEEDYSNKVVLVLGNEGSGIRKKVREHCD 204
Query: 200 TILSVKMRRDFDSLNVSVAAGILMDKI 226
++ + M +SLNVSVA+GIL+ +I
Sbjct: 205 KLIKIPMYGQINSLNVSVASGILLSRI 231
>pir||S77837 hypothetical protein MC105 - Mycoplasma capricolum
emb|CAA83745.1| (Z33076) rRNA methylase [Mycoplasma capricolum]
Length = 223
Score = 66.6 bits (161), Expect = 2e-10
Identities = 50/182 (27%), Positives = 88/182 (47%), Gaps = 9/182 (4%)
Query: 50 DNKKAQSLAKGGNHQGVLAKVE----LPLAVSLKEVKKAQK--LLVLCGITDVGNIGGIF 103
+NK Q L HQG++A+++ P L ++ +K +LVL I D N G I
Sbjct: 30 ENKLDQLLKTNELHQGIIAQIKDFNYTPFDELLNDLNTKEKSLVLVLDQIHDPYNFGAII 89
Query: 104 RSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLG 162
RS L + G+I+ K++ ++++S G +D+ S N + I LK +GF
Sbjct: 90 RSCSLLNVDGIIILDKKQVQVNSTVLKTSSGSAFDIKISKTNNLNNAIKILKNNGFWIYA 149
Query: 163 ASMQGSS--QIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAG 220
++ +S + K + +G+E +G+S+ + D + V ++ DS N SVA
Sbjct: 150 TNLNQNSTDMTKTQFANKSVVIIGNEQKGVSELLTKNSDFNIYVPSNKNIDSFNSSVACS 209
Query: 221 IL 222
I+
Sbjct: 210 II 211
>ref|NP_355393.1| (NC_003062) AGR_C_4428p [Agrobacterium tumefaciens] [Agrobacterium
tumefaciens str. C58 (Cereon)]
gb|AAK88178.1| (AE008157) AGR_C_4428p [Agrobacterium tumefaciens str. C58
(Cereon)]
Length = 285
Score = 66.2 bits (160), Expect = 3e-10
Identities = 46/167 (27%), Positives = 84/167 (49%), Gaps = 7/167 (4%)
Query: 63 HQGVLAKVELPLAVSLKEVKKA----QKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD- 117
H+G+LA L+++ A +LV CGI++ N+G +FR+A V+LD
Sbjct: 110 HRGILALGRRVRDDGLEQMTAALPASSLVLVGCGISNHDNLGAMFRNAAAFYADAVLLDE 169
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL-SL 176
+ Y +R S+G + +P+ ++++ L GF G S G ++I ++
Sbjct: 170 TCCDPLYRKALRVSVGSVLSVPYHRGGGAVEMLERLSEEGFAIWGLSPDGKTEIRDIPRS 229
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
++ AL +G+E EGL + +L++ T + DSLN A+G+ +
Sbjct: 230 ERMALVIGTEGEGLPQSVLSRFQT-ARIAQSPQVDSLNAGTASGLAL 275
>ref|NP_533113.1| (NC_003304) RNA methylase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
gb|AAL43429.1| (AE009191) RNA methylase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
Length = 232
Score = 66.2 bits (160), Expect = 3e-10
Identities = 46/167 (27%), Positives = 84/167 (49%), Gaps = 7/167 (4%)
Query: 63 HQGVLAKVELPLAVSLKEVKKA----QKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD- 117
H+G+LA L+++ A +LV CGI++ N+G +FR+A V+LD
Sbjct: 57 HRGILALGRRVRDDGLEQMTAALPASSLVLVGCGISNHDNLGAMFRNAAAFYADAVLLDE 116
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL-SL 176
+ Y +R S+G + +P+ ++++ L GF G S G ++I ++
Sbjct: 117 TCCDPLYRKALRVSVGSVLSVPYHRGGGAVEMLERLSEEGFAIWGLSPDGKTEIRDIPRS 176
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
++ AL +G+E EGL + +L++ T + DSLN A+G+ +
Sbjct: 177 ERMALVIGTEGEGLPQSVLSRFQT-ARIAQSPQVDSLNAGTASGLAL 222
>ref|NP_606651.1| (NC_003485) putative rRNA methylase [Streptococcus pyogenes
MGAS8232]
gb|AAL97150.1| (AE009982) putative rRNA methylase [Streptococcus pyogenes
MGAS8232]
Length = 245
Score = 65.9 bits (159), Expect = 3e-10
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 8/182 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRS 105
++ V + + L + QG++A+VE+P + K K LVL + D GN+G I R+
Sbjct: 64 LVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKG--KYLVLEDVQDPGNLGTIIRT 121
Query: 106 AYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGAS 164
A GV L + + ++ + +RS G + LP + L EL+ L +
Sbjct: 122 ADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIW-RTDVYQLCRELQEYKTPILATT 180
Query: 165 MQGSSQIENLSL---KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
+ S ++ SL ++ AL LG+E +G+S ++ A D ++ + M +SLNV+VAAGI
Sbjct: 181 LSKKS-VDYKSLTHHERLALVLGNEGQGISAEMAALADQLVHITMPGQAESLNVAVAAGI 239
Query: 222 LM 223
L+
Sbjct: 240 LI 241
>ref|NP_268681.1| (NC_002737) putative rRNA methylase [Streptococcus pyogenes]
[Streptococcus pyogenes M1 GAS]
gb|AAK33402.1| (AE006499) putative rRNA methylase [Streptococcus pyogenes M1 GAS]
Length = 245
Score = 65.9 bits (159), Expect = 3e-10
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 8/182 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRS 105
++ V + + L + QG++A+VE+P + K K LVL + D GN+G I R+
Sbjct: 64 LVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKG--KYLVLEDVQDPGNLGTIIRT 121
Query: 106 AYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGAS 164
A GV L + + ++ + +RS G + LP + L EL+ L +
Sbjct: 122 ADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIW-RTDVYQLCRELQEYETPILATT 180
Query: 165 MQGSSQIENLSL---KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
+ S ++ SL ++ AL LG+E +G+S ++ A D ++ + M +SLNV+VAAGI
Sbjct: 181 LSKKS-VDYKSLTHHERLALVLGNEGQGISAEMAALADQLVHITMPGQAESLNVAVAAGI 239
Query: 222 LM 223
L+
Sbjct: 240 LI 241
>emb|CAC44352.1| (AJ410308) YfiF protein [Erwinia chrysanthemi]
Length = 366
Score = 65.1 bits (157), Expect = 6e-10
Identities = 56/227 (24%), Positives = 100/227 (43%), Gaps = 8/227 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSL--AKGGN 62
+YG+ L S E + + +E+ + AL+ N + L A G
Sbjct: 131 VYGENACQALFLSRPEAIVRGWFLQEVTPRFREALRWMAANRKAYHVVEDDELVRASGTE 190
Query: 63 HQG-----VLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
H G + + L +A L E +L L + + N+GGI RS G+ G++++
Sbjct: 191 HHGGVCFLIKKRHGLDVAAYLSEAGDTDCVLALEDVGNPHNLGGIMRSCAHFGVKGLLVN 250
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLK 177
A +L VR++ G + +D + + + +G+ + S + + +SL
Sbjct: 251 DAAQLESGAAVRTAEGGAEHVKAISADGLVDALAQFRAAGYTIVTTSSHKGTTLSKVSLP 310
Query: 178 -KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K + LG E +GLS + D +S+ + +SLN+SVA GIL+
Sbjct: 311 AKTVIVLGQEGDGLSDSAWQQGDVKVSIDGTGNVESLNISVATGILL 357
>ref|NP_336137.1| (NC_002755) rRNA methylase, putative [Mycobacterium tuberculosis
CDC1551]
gb|AAK45951.1| (AE007031) rRNA methylase, putative [Mycobacterium tuberculosis
CDC1551]
Length = 260
Score = 64.7 bits (156), Expect = 7e-10
Identities = 55/208 (26%), Positives = 100/208 (47%), Gaps = 7/208 (3%)
Query: 22 LQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV 81
++E+++++ ++ L ++ V + A++L+ G++A +LP A L++V
Sbjct: 44 VREVFVTEVAARRHELLLAAHEASVHLVTERAAKALSDTVTPAGLVAVCDLP-ATRLEDV 102
Query: 82 KKA--QKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDL 138
Q + V I + GN G + R A +G VIL Y G +R+S G ++ +
Sbjct: 103 LAGSPQLIAVTVEIREPGNAGTVIRIADAMGAAAVILAGRSVDPYNGKCLRASTGSIFAI 162
Query: 139 PFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN---LSLKKCALFLGSEHEGLSKKIL 195
P V P+ I +L+ +G L ++ G +++ L + A G E GLS +I
Sbjct: 163 PVVVAPDVGAAIADLRAAGLQVLATAVDGEMALDDADRLLAEPTAWLFGPEAHGLSAEIA 222
Query: 196 AKMDTILSVKMRRDFDSLNVSVAAGILM 223
A D + + M +SLNV+ AA I +
Sbjct: 223 ALADHRVHIPMSGGAESLNVAAAAAICL 250
>ref|NP_216160.1| (NC_000962) tsnR [Mycobacterium tuberculosis H37Rv]
pir||G70619 probable 23s rrnamethyltransferase - Mycobacterium tuberculosis
(strain H37RV)
emb|CAB06638.1| (Z85982) tsnR [Mycobacterium tuberculosis H37Rv]
Length = 260
Score = 64.3 bits (155), Expect = 1e-09
Identities = 55/208 (26%), Positives = 100/208 (47%), Gaps = 7/208 (3%)
Query: 22 LQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV 81
++E+++++ ++ L ++ V + A++L+ G++A +LP A L++V
Sbjct: 44 VREVFVTEVAARRHELLLAAHEASVHLVTERAAKALSDTVTPAGLVAVCDLP-ATRLEDV 102
Query: 82 KKA--QKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDL 138
Q + V I + GN G + R A +G VIL Y G +R+S G ++ +
Sbjct: 103 LAGSPQLIAVTVEIREPGNAGTVIRIADAMGAAAVILAGRSVDPYNGKCLRASTGSIFAI 162
Query: 139 PFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN---LSLKKCALFLGSEHEGLSKKIL 195
P V P+ I +L+ +G L ++ G +++ L + A G E GLS +I
Sbjct: 163 PVVVAPDVGAAIADLRAAGLQVLATAVDGEMALDDADRLLAEPTAWLFGPEAHGLSAEIA 222
Query: 196 AKMDTILSVKMRRDFDSLNVSVAAGILM 223
A D + + M +SLNV+ AA I +
Sbjct: 223 ALADHRVHILMSGGAESLNVAAAAAICL 250
>ref|NP_636890.1| (NC_003902) tRNA/rRNA methyltransferase [Xanthomonas campestris pv.
campestris str. ATCC 33913]
gb|AAM40814.1| (AE012253) tRNA/rRNA methyltransferase [Xanthomonas campestris pv.
campestris str. ATCC 33913]
Length = 249
Score = 63.9 bits (154), Expect = 1e-09
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 9/188 (4%)
Query: 45 NIIKVDNKKAQSLAKGGNHQGVLAK-------VELPLAVSLKEVKKAQKLLVLCGITDVG 97
++ +V+ + + HQGV A+ E L ++ + +L+L G+ D
Sbjct: 52 DVRRVNTQALDGVGGQVRHQGVAARYAAARLWAENELEGLVEAAQGRALVLILDGVQDPH 111
Query: 98 NIGGIFRSAYCLGMGGVILDFAKELAYEGIVR-SSLGLMYDLPFSVMPNTLDLINELKTS 156
N+G RSA G+ V++ K VR +S G +P + N + +L+
Sbjct: 112 NLGACLRSAAAAGVTAVVIPKDKSATVNATVRKTSAGAADRIPVVAVTNLARCLRDLQKQ 171
Query: 157 GFLCLGASMQGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNV 215
G G + + + + ++ L+ L LG E +GL + D ++ + M D +SLNV
Sbjct: 172 GVWLYGLAGEAEASLYSVDLRGNVGLVLGGEGDGLRRLTREHCDGLVKIPMPGDIESLNV 231
Query: 216 SVAAGILM 223
SVA G+ +
Sbjct: 232 SVATGVTL 239
>ref|NP_420003.1| (NC_002696) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
gb|AAK23171.1| (AE005796) spoU rRNA methylase family protein [Caulobacter
crescentus CB15]
Length = 263
Score = 63.5 bits (153), Expect = 2e-09
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 10/197 (5%)
Query: 33 KKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLA---KVELPLAVSLKEVKKAQKLLV 89
KK A KA +I+V+ + + +++ N Q V+A +V PL+ + E A +
Sbjct: 66 KKAVAACLKAGGEVIEVNREILEKVSRRDNPQAVVAVFKQVFTPLSAIVPE--SAPCWVA 123
Query: 90 LCGITDVGNIGGIFRSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTL 147
+ + D GN+G + R+A G GGVIL D + EG VR+++G ++ + +
Sbjct: 124 MQAVRDPGNLGTVIRTADAAGCGGVILVGDCVDPYSVEG-VRATMGSIFAVKIA-KATIP 181
Query: 148 DLINELKTSGFLCLGASMQGSSQIENLSLKKCALFL-GSEHEGLSKKILAKMDTILSVKM 206
+ + +T +G + + ++ K +L L G+E +GL ++ A D + + M
Sbjct: 182 EFLAWRETWPGSVVGTLLTATVDHKSADYVKPSLILMGNEQQGLPPELAAACDVNVKIPM 241
Query: 207 RRDFDSLNVSVAAGILM 223
R DSLN+SVA GI++
Sbjct: 242 RGRADSLNLSVATGIMI 258
>ref|NP_359380.1| (NC_003098) Possible rRNA/tRNA methylase [Streptococcus pneumoniae
R6]
gb|AAL00591.1| (AE008543) Possible rRNA/tRNA methylase [Streptococcus pneumoniae
R6]
Length = 252
Score = 63.5 bits (153), Expect = 2e-09
Identities = 56/189 (29%), Positives = 91/189 (47%), Gaps = 14/189 (7%)
Query: 42 ACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQ----KLLVLCGITDVG 97
A P + + LA QG++A V+ +EV +A K L L + D G
Sbjct: 67 AFPQTVWISEDILLDLADSQTPQGIVAVVQK------EEVGQADLSQGKFLFLEDVQDPG 120
Query: 98 NIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTS 156
N+G I R+A G GVI+ D + ++ +RS G + LP M + L++E K
Sbjct: 121 NVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYRMTSPA-LLDETKKV 179
Query: 157 GFLCLGASMQGSS--QIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLN 214
L ++ S E S++ L +G+E +G+S + D ++ + M+ +SLN
Sbjct: 180 AIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESADQLVHISMKGQAESLN 239
Query: 215 VSVAAGILM 223
V+VAAGIL+
Sbjct: 240 VAVAAGILI 248
>ref|NP_643623.1| (NC_003919) tRNA/rRNA methyltransferase [Xanthomonas axonopodis pv.
citri str. 306]
gb|AAM38159.1| (AE011977) tRNA/rRNA methyltransferase [Xanthomonas axonopodis pv.
citri str. 306]
Length = 305
Score = 63.5 bits (153), Expect = 2e-09
Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 12/228 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN----IIKVDNKKAQSLAKG 60
+YG + + + E L+++YLS E F AL C V+ LA
Sbjct: 65 LYGINAVQAVFKTRPEALRKLYLS-EARIPQFKALLAWCVTQRIGYRVVEEADLSKLAAS 123
Query: 61 GNHQGVLAKV----ELPLAVSLKEVKKAQKL-LVLCGITDVGNIGGIFRSAYCLGMGGVI 115
+H+GV+A+V PL L + + L L L G+ + N G I RS+ G+ G++
Sbjct: 124 AHHEGVVAEVLRVTPHPLQEWLAALPQGPVLALWLDGVGNPHNFGAILRSSAHFGVAGLL 183
Query: 116 LDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL 174
L L G R + G +P +P+T + +L+ +GF + G +
Sbjct: 184 LPAGSTLGLSGAAARVAEGGAEAVPLVQLPDTATALAQLRQAGFAIAATLVDGGQDVFAA 243
Query: 175 SLKKCALF-LGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
+L + ++ +G+E +G+ + D LS++ +SLNV+ A +
Sbjct: 244 ALPQRLVYVMGAESDGMDRAFARDCDLQLSIRGSGKVESLNVASATAV 291
>ref|NP_600054.1| (NC_003450) COG0566:rRNA methylases [Corynebacterium glutamicum]
dbj|BAB98218.1| (AP005276) rRNA methylases [Corynebacterium glutamicum ATCC 13032]
Length = 276
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/187 (27%), Positives = 94/187 (49%), Gaps = 13/187 (6%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV-KKAQKLLVLCGITDVGNIGGIFR 104
+ +V + +A H+G+LA + S+ +V + A+ ++VL G+ D NIG +FR
Sbjct: 82 VYEVSRELLAEVAGFDMHRGLLATADRTEEASVAQVLENARTVVVLEGVGDHENIGSMFR 141
Query: 105 SAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDL----INELKTSGFL 159
+A +G+ ++ + + Y +VR S+G + LPF+ + T + +LK +GF
Sbjct: 142 NAAGMGVDAILFGNGCADPLYRRVVRVSMGHVLRLPFAHLEGTYTTWQRSLEQLKEAGFH 201
Query: 160 CLGASMQGSSQIENLS-----LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLN 214
+ S+ + E+L K AL +G+E GL++ + D + M DSLN
Sbjct: 202 LV--SLTPDPEAEHLEDALAGKDKVALLVGAEGPGLTEHAMRATDVRARIPMAPGTDSLN 259
Query: 215 VSVAAGI 221
++ +A I
Sbjct: 260 LATSAAI 266
>ref|NP_301351.1| (NC_002677) putative methyltransferase [Mycobacterium leprae]
emb|CAC29832.1| (AL583918) putative methyltransferase [Mycobacterium leprae]
Length = 278
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/213 (23%), Positives = 95/213 (43%), Gaps = 11/213 (5%)
Query: 25 IYLSKEIDKKLFFALKKACP---NIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV 81
+ L E+DK+L ++ +A I++V + HQG+ +V V ++
Sbjct: 60 VALGTEVDKRLTESVMRAADVGVAILEVPRTYLDRITNNHLHQGIALQVPPYHYVHSDDL 119
Query: 82 KKAQK------LLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSLGL 134
A L+ L I+D N+G I RS G+++ + + + R+S G
Sbjct: 120 LAAATDSPPALLVALDNISDPRNLGAIVRSVAAFSGHGILIPQRRSASVTAVAWRTSAGA 179
Query: 135 MYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS-LKKCALFLGSEHEGLSKK 193
+P + N + G +G G + +++L A+ +GSE +GLS+
Sbjct: 180 AARIPVARATNLTRALKVWADQGLRVIGLDHDGDTALDDLDGTDPLAVVVGSEGKGLSRL 239
Query: 194 ILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ D ++S+ M +SLN SVA G+++ +I
Sbjct: 240 VRHSCDEVVSIPMAGQVESLNASVAVGVVLAEI 272
>ref|NP_623287.1| (NC_003869) rRNA methylase [Thermoanaerobacter tengcongensis]
gb|AAM24891.1| (AE013124) rRNA methylase [Thermoanaerobacter tengcongensis]
Length = 266
Score = 62.8 bits (151), Expect = 3e-09
Identities = 44/180 (24%), Positives = 90/180 (49%), Gaps = 6/180 (3%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRS 105
+I++ NK + ++ Q ++A V +P+ +K+ ++ + D GN+G I R+
Sbjct: 66 LIRIANKLFKKISDTVTPQKIMAIVRMPVYREEDFIKEEGVYVIADNVQDPGNLGTIIRT 125
Query: 106 AYCLGMGGVI-LDFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGAS 164
A G V ++ + ++ ++R+S+G ++ +P N +++ +LK G
Sbjct: 126 ADAFGADAVFTINNSVDIYNPKVLRASMGSIFHIPVIATAN--EVLYKLKGKGVKVFATH 183
Query: 165 MQGSSQIENLSLKK-CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
++G + + + K A LG+E G+S L +D + + M +SLNVS+AA I +
Sbjct: 184 LKGEKFVHEVEIDKGTAFILGNEARGVSS--LDFVDGFIKIPMTGRAESLNVSIAAAIFL 241
>ref|NP_662765.1| (NC_002932) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
gb|AAM73107.1| (AE012940) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
Length = 263
Score = 62.8 bits (151), Expect = 3e-09
Identities = 52/176 (29%), Positives = 80/176 (44%), Gaps = 5/176 (2%)
Query: 57 LAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVIL 116
LA+ + QGV+A P + + ++ L + D GN+G I R+A G VI
Sbjct: 87 LAQTTSPQGVVAAFRKPESGEFRPASARSFVVALDDVQDPGNVGTIIRTAAWFGAEAVIC 146
Query: 117 DFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS-QIENL 174
Y VRSS G ++ L P+ + L+ GF +++ G +
Sbjct: 147 GRGTADPYNAKSVRSSAGSIFALAIDTTPDLAKTLRRLQADGFTVAASALDGQDYRFFAE 206
Query: 175 SLKKCALFLGSEHEGLSKKILAKMDTILSVK---MRRDFDSLNVSVAAGILMDKIN 227
+ L +G+E G+S +ILA D L + R +SLN SV+AGILM I+
Sbjct: 207 WPARRVLVIGNEANGISAEILALADRRLLIPPAGARPAVESLNASVSAGILMATIH 262
>ref|NP_464743.1| (NC_003210) similar to rRNA methylase [Listeria monocytogenes
EGD-e]
emb|CAC99296.1| (AL591978) similar to rRNA methylase [Listeria monocytogenes]
Length = 252
Score = 62.4 bits (150), Expect = 4e-09
Identities = 49/184 (26%), Positives = 94/184 (50%), Gaps = 10/184 (5%)
Query: 45 NIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKK--AQKLLVLCGITDVGNIGGI 102
++ ++ + + +++ QGV A V A S ++ +KLL++ + D GN+G +
Sbjct: 69 DVFEISTEISHLISETMTEQGVFAVV----ATSEPDMMLLYGKKLLLVDAVQDPGNVGTL 124
Query: 103 FRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G V+L Y ++RS+ G + +P + + D I L+ G +
Sbjct: 125 IRTADAAGYDCVVLGKGSADLYNPKVIRSTQGSHFHIPV-IQADLFDWIANLEEEGVPVI 183
Query: 162 GASMQGSSQIENLSLKK--CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
GA + ++ N K+ AL +G+E G+S ++ ++ + + + D +SLNV+VAA
Sbjct: 184 GAVLDDQAKSLNDMTKRDTLALMVGNEGNGISPELQDRLSEKVYIPIYGDSESLNVAVAA 243
Query: 220 GILM 223
GIL+
Sbjct: 244 GILL 247
>ref|NP_077955.1| (NC_002162) rRNA methylase [Ureaplasma urealyticum]
pir||A82931 rRNA methylase UU124 [imported] - Ureaplasma urealyticum
gb|AAF30530.1|AE002113_4 (AE002113) rRNA methylase [Ureaplasma urealyticum]
Length = 239
Score = 62.0 bits (149), Expect = 5e-09
Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 12/228 (5%)
Query: 6 YGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQG 65
+GK+ ++ + + Q + LSK + K I V+ + NHQ
Sbjct: 5 FGKKALLDAIGNKQSISKVYLLSKNYELINLINKNKITYEI--VNEAWFKQFDHSLNHQN 62
Query: 66 V--------LAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
+ K L + L + KK +L+L I D N G I R+A G+ +I
Sbjct: 63 IAFKLVKKNFQKTSLESFLKLIKDKKNALVLILDEIEDPRNFGAIIRTANGFGVDAIIYK 122
Query: 118 FAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSL 176
+ + +V ++S+G + + + N + I L+ GF S+ S E +
Sbjct: 123 KHHQASINDLVIKTSMGAINYIYMIEVNNLSNTIKNLQDEGFWVYATSLLKSQPYEKVDY 182
Query: 177 KKCALFL-GSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+F+ G+E++G+S IL D + + M D SLNV VA GI++
Sbjct: 183 ANKTVFIVGNENKGVSPLILKNADQSIRIDMFGDVQSLNVGVATGIIL 230
>ref|NP_212650.1| (NC_001318) rRNA methylase (yacO) [Borrelia burgdorferi]
sp|O51468|Y516_BORBU Hypothetical tRNA/rRNA methyltransferase BB0516
pir||C70164 rRNA methylase (yacO) homolog - Lyme disease spirochete
gb|AAC66889.1| (AE001154) rRNA methylase (yacO) [Borrelia burgdorferi]
Length = 228
Score = 62.0 bits (149), Expect = 5e-09
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 19/198 (9%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLK-------------EVKKAQKLLVLCG 92
II+++ + + K +H+G K++L ++K + K+ +L+L
Sbjct: 26 IIRINTNELDKILKNKDHRGFALKLKLEKNKNVKTQTKDFENLLETFKKKENAFILLLDE 85
Query: 93 ITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG--IVRSSLGLMYDLPFSVMPNTLDLI 150
I D N G I R+A + +++ K A + ++R+S G + + N + I
Sbjct: 86 IEDPQNFGAILRTAEQFSID-LVITTQKRSAKDNSTVLRTSSGASQYVKKMTVTNINNTI 144
Query: 151 NELKTSGFLCLGASMQGSSQIENLSL--KKCALFLGSEHEGLSKKILAKMDTILSVKMRR 208
N LK GF ++G I + + KK AL LG+E +G+ K I D ++ +
Sbjct: 145 NLLKNYGFWIYTGDIKGQD-INKIKINDKKIALILGNEGKGVHKLIKENSDFLIRIPTSG 203
Query: 209 DFDSLNVSVAAGILMDKI 226
DSLNVSV+ GIL+ +I
Sbjct: 204 KIDSLNVSVSTGILIFEI 221
>ref|NP_346400.1| (NC_003028) spoU rRNA Methylase family protein [Streptococcus
pneumoniae TIGR4]
gb|AAK76040.1| (AE007487) spoU rRNA Methylase family protein [Streptococcus
pneumoniae TIGR4]
Length = 246
Score = 62.0 bits (149), Expect = 5e-09
Identities = 54/174 (31%), Positives = 87/174 (49%), Gaps = 14/174 (8%)
Query: 57 LAKGGNHQGVLAKVELPLAVSLKEVKKAQ----KLLVLCGITDVGNIGGIFRSAYCLGMG 112
LA QG++A V+ +EV +A K L L + D GN+G I R+A G
Sbjct: 76 LADSQTPQGIVAVVQK------EEVGQADLSQGKFLFLEDVQDPGNVGTIIRTADAAGFT 129
Query: 113 GVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS-- 169
GVI+ D + ++ +RS G + LP M + L++E K L ++ S
Sbjct: 130 GVIVSDKSADIYSLKTLRSMQGSHFHLPIYRMTSQA-LLDETKKVAIPVLATTLSKDSVD 188
Query: 170 QIENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
E S++ L +G+E +G+S + D ++ + M+ +SLNV+VAAGIL+
Sbjct: 189 YRELPSIENFVLVMGNEGQGISPLMAESADQLVHISMKGQAESLNVAVAAGILI 242
>ref|NP_335332.1| (NC_002755) spoU rRNA methylase family protein [Mycobacterium
tuberculosis CDC1551]
gb|AAK45146.1| (AE006977) spoU rRNA methylase family protein [Mycobacterium
tuberculosis CDC1551]
Length = 242
Score = 61.6 bits (148), Expect = 6e-09
Identities = 51/166 (30%), Positives = 82/166 (48%), Gaps = 7/166 (4%)
Query: 63 HQGVLAKVE-LPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFA-K 120
++GVLA +P + V A+ + VL G+ D N+G IFR+A L + V+
Sbjct: 61 NRGVLAAARRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVVFGTGCA 120
Query: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS-----QIENLS 175
+ Y VR S+G +P++ + + LK SGF L + G++ I +S
Sbjct: 121 DPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMTPHGNACKLPEAIAAVS 180
Query: 176 LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
++ AL +G+E GL+ L D + + M R DSLNV+ AA +
Sbjct: 181 HERIALLVGAEGPGLTAAALRISDVRVRIPMSRGTDSLNVATAAAL 226
>ref|NP_215396.1| (NC_000962) hypothetical protein Rv0881 [Mycobacterium tuberculosis
H37Rv]
sp|Q10543|Y881_MYCTU Hypothetical tRNA/rRNA methyltransferase RV0881
pir||F70780 hypothetical protein Rv0881 - Mycobacterium tuberculosis (strain
H37RV)
emb|CAA97388.1| (Z73101) hypothetical protein Rv0881 [Mycobacterium tuberculosis
H37Rv]
Length = 288
Score = 61.6 bits (148), Expect = 6e-09
Identities = 51/166 (30%), Positives = 82/166 (48%), Gaps = 7/166 (4%)
Query: 63 HQGVLAKV-ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFA-K 120
++GVLA +P + V A+ + VL G+ D N+G IFR+A L + V+
Sbjct: 107 NRGVLAAAGRVPEPSVAQVVAGARTVAVLEGVNDHENLGSIFRNAAGLSVDAVVFGTGCA 166
Query: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSS-----QIENLS 175
+ Y VR S+G +P++ + + LK SGF L + G++ I +S
Sbjct: 167 DPLYRRAVRVSMGHALLVPYARAADWPTELMTLKESGFRLLAMTPHGNACKLPEAIAAVS 226
Query: 176 LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
++ AL +G+E GL+ L D + + M R DSLNV+ AA +
Sbjct: 227 HERIALLVGAEGPGLTAAALRISDVRVRIPMSRGTDSLNVATAAAL 272
>ref|NP_641901.1| (NC_003919) tRNA/rRNA methyltransferase [Xanthomonas axonopodis pv.
citri str. 306]
gb|AAM36437.1| (AE011789) tRNA/rRNA methyltransferase [Xanthomonas axonopodis pv.
citri str. 306]
Length = 249
Score = 61.6 bits (148), Expect = 6e-09
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Query: 45 NIIKVDNKKAQSLAKGGNHQGVLAK-------VELPLAVSLKEVKKAQKLLVLCGITDVG 97
++ +V+ + + HQGV A+ E L ++ +L+L G+ D
Sbjct: 52 DVRRVNTQALDGVGGQVRHQGVAARYAAARLWAENELEGLVEAAAGRALVLILDGVQDPH 111
Query: 98 NIGGIFRSAYCLGMGGVILDFAKELAYEGIVR-SSLGLMYDLPFSVMPNTLDLINELKTS 156
N+G RSA G+ V++ K VR +S G +P + N + +L+
Sbjct: 112 NLGACLRSAAAAGVTAVVIPKDKSATVNATVRKTSAGAADRIPVVAVTNLARCLRDLQKQ 171
Query: 157 GFLCLGASMQGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNV 215
G G + + + + ++ L+ L LG E +GL + D ++ + M + +SLNV
Sbjct: 172 GVWLYGLAGEAEASLYSVDLRGNVGLVLGGEADGLRRLTREHCDGLVKIPMPGEIESLNV 231
Query: 216 SVAAGILM 223
SVA G+ +
Sbjct: 232 SVATGVTL 239
>ref|NP_470518.1| (NC_003212) similar to rRNA methylase [Listeria innocua]
emb|CAC96412.1| (AL596167) similar to rRNA methylase [Listeria innocua]
Length = 252
Score = 61.2 bits (147), Expect = 8e-09
Identities = 47/184 (25%), Positives = 96/184 (51%), Gaps = 10/184 (5%)
Query: 45 NIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKK--AQKLLVLCGITDVGNIGGI 102
++ ++ ++ + ++ QGV A V A+S ++ +KLL++ + D GN+G +
Sbjct: 69 DVFEISSEISHLISDTMTEQGVFAVV----AISEPDMMLLYGKKLLLVDAVQDPGNVGTL 124
Query: 103 FRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G V+L Y ++RS+ G + +P + + + + L+ G +
Sbjct: 125 IRTADAAGYDCVVLGRGSADLYNPKVIRSTQGSHFHIPV-IQADLFEWVANLEEEGVPVI 183
Query: 162 GASMQGSSQIENLSLKK--CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
GA + ++ N K+ AL +G+E G+S+++ ++ + + + D +SLNV+VAA
Sbjct: 184 GAVLDDQAKSLNDMPKRETLALMVGNEGNGISEELQDRLSEKVYIPIYGDSESLNVAVAA 243
Query: 220 GILM 223
GIL+
Sbjct: 244 GILL 247
>ref|XP_126373.1| (XM_126373) similar to hypothetical protein FLJ22578 [Mus musculus]
Length = 327
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/203 (29%), Positives = 91/203 (44%), Gaps = 26/203 (12%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPL-------AVSLKEVKKAQKL-LVLCGITDVG 97
+++ +K +L HQGV +V PL A Q+L LVL G+ D
Sbjct: 97 VLRPRRQKLDALCGYQVHQGVCMEVS-PLRPRPCDEAADTSSGDDPQQLWLVLEGLQDPR 155
Query: 98 NIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTS 156
N+G + RSA+ LG+ VI +V ++S G M + P+ +
Sbjct: 156 NLGAVMRSAHFLGVDRVITSQRNSCPLTPVVSKASAGAMEVMDVFATPDLPGFLQAKAQQ 215
Query: 157 GFL------CLGASMQGSSQIENLSL------KKCALFLGSEHEGLSKKILAKMDTILSV 204
G+L C G + SS++ S + L LGSE GLS+++ A +L++
Sbjct: 216 GWLVVGTVGCPGPEISQSSKVPITSCLEFVWDRPTLLVLGSEGSGLSQEVFASCQLLLTI 275
Query: 205 KMRR----DFDSLNVSVAAGILM 223
RR +SLNVSVA GIL+
Sbjct: 276 LPRRHLPPGLESLNVSVATGILL 298
>sp|P18644|TSNR_STRCN rRNA (adenosine-2'-O-)-methyltransferase (23S rRNA [AM1067]
2'-O-methyltransferase) (23S rRNA methylase)
(Thiostrepton-resistance methylase)
pir||S28369 rRNA methylase - Streptomyces cyaneus
emb|CAA26234.1| (X02392) rRNA methylase [Streptomyces cyaneus]
emb|CAA67009.1| (X98363) Thiostrepton resistance protein [Cloning vector pIJ2581]
dbj|BAA93040.1| (AB040452) rRNA methylase [Shuttle vector pRES19]
emb|CAC93942.1| (AJ414669) thiostrepton resistance gene [Cloning vector pIJ6021]
gb|AAL61980.1| (AY072037) thiostrepton resistance protein TsrR [Expression vector
pANT849]
gb|AAL61984.1| (AY072038) thiostrepton resistance protein TsrR [Expression vector
pANT1200]
Length = 269
Score = 60.1 bits (144), Expect = 2e-08
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 6/180 (3%)
Query: 49 VDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQ-KLLVLCGITDVGNIGGIFRSAY 107
+D+ L KG +P ++ + ++VL G+ VGNIG I R++
Sbjct: 79 IDSSIVNQLFKGERKAKTFGIARVPRPARFGDIASRRGDVVVLDGVKIVGNIGAIVRTSL 138
Query: 108 CLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASM 165
LG G+IL +A + R+S G ++ LP V+ + I ++ SG +
Sbjct: 139 ALGASGIILVDSDITSIADRRLQRASRGYVFSLPV-VLSGREEAIAFIRDSGMQLMTLKA 197
Query: 166 QGSSQIENL--SLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
G ++ L + + AL GSE G S +S+ M +SLNVSV+ GI +
Sbjct: 198 DGDISVKELGDNPDRLALLFGSEKGGPSDLFEEASSASVSIPMMSQTESLNVSVSLGIAL 257
>emb|CAB64790.1| (AJ242786) YjfH protein [Burkholderia sp.]
Length = 247
Score = 60.1 bits (144), Expect = 2e-08
Identities = 49/185 (26%), Positives = 86/185 (46%), Gaps = 7/185 (3%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKV-ELPLAVSLKE----VKKAQKLLVLCGITDVGNIG 100
+I D + +L+ HQGV+A+V E A SL+ ++ LL L G+TD N+G
Sbjct: 52 LIAADASRLNALSGEKRHQGVVARVTEATRAHSLETLLDTIEGQPLLLALDGVTDPHNLG 111
Query: 101 GIFRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFL 159
R A G VI + +++ G +P+ + N + LK +G
Sbjct: 112 ACLRVADGAGAHAVIAPRRRAAGLTAAAAKAANGAAETVPYLTVINLARALRALKNAGIQ 171
Query: 160 CLGASMQGSSQIENLSLKKC-ALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVA 218
+G + ++ + ++ L AL +G+E G+ + D ++ + + SLNVSVA
Sbjct: 172 VIGTADDATTSLFDIQLDGALALVMGAEGAGMRRLTREACDEVVRIPLAGHVQSLNVSVA 231
Query: 219 AGILM 223
+GI +
Sbjct: 232 SGICL 236
>ref|NP_326135.1| (NC_002771) TRNA/RRNA METHYLTRANSFERASE [Mycoplasma pulmonis]
emb|CAC13477.1| (AL445564) TRNA/RRNA METHYLTRANSFERASE [Mycoplasma pulmonis]
Length = 250
Score = 60.1 bits (144), Expect = 2e-08
Identities = 57/226 (25%), Positives = 104/226 (45%), Gaps = 19/226 (8%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNH 63
+I G +I L ++ E +IY +K +K F K+ ++ + N + +
Sbjct: 32 LIEGDHLIDEALKNNFEC--QIYSTKPNEKHDFLITKEVLKHVSLLVNSEQK-------- 81
Query: 64 QGVLAKVELP-LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKEL 122
+AKV++ + + + +L L + D NIG + RSA +I D ++
Sbjct: 82 ---IAKVKIKETSNDFLNIDQKSNILFLNNLQDPTNIGTLLRSALSFNFKNIIYD-NLDI 137
Query: 123 AYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQ--IENLSLKKCA 180
I+R+S G ++ L F N + L+ + +G + S +N KK
Sbjct: 138 YNPKIIRASQGAIFALNFFKSKNHQKTLKYLQEKNYEIIGTFLHSDSTNLYQNSFDKKIV 197
Query: 181 LFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
L LG+E G+ K+IL +D + V + +F+SLNV++A I+M +
Sbjct: 198 LILGNEGLGIEKEILTLIDKNVIVPI--NFESLNVAIAGSIIMSYV 241
>ref|NP_301995.1| (NC_002677) putative rRNA methyltransferase [Mycobacterium leprae]
emb|CAC31778.1| (AL583921) putative rRNA methyltransferase [Mycobacterium leprae]
Length = 259
Score = 59.7 bits (143), Expect = 2e-08
Identities = 50/186 (26%), Positives = 84/186 (44%), Gaps = 6/186 (3%)
Query: 43 CPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLC-GITDVGNIGG 101
CP + V + A++L+ G++A E+P + + +L+V I++ GN G
Sbjct: 66 CP-VHPVSERAAKALSDTVTPTGLIAVCEMPTTRLATVLAGSPQLVVAAVEISEPGNAGT 124
Query: 102 IFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLC 160
+ R A +G VI Y G +RSS G ++ + V + + EL+ +G
Sbjct: 125 VIRIADAMGAAAVIFGGYTVDPYNGKCLRSSAGSIFSITVVVASDAYAAVTELRAAGLQV 184
Query: 161 LGASMQGSSQIEN---LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSV 217
L + G + ++ L K A GSE GLS +I D + + M +SLNV+
Sbjct: 185 LATMVDGETSLDEAKPLLGKPTAWLFGSEPHGLSTEIAEAADYRVRIPMVGGVESLNVAA 244
Query: 218 AAGILM 223
A I +
Sbjct: 245 TAAICL 250
>ref|NP_628410.1| (NC_003888) putative tRNA/rRNA methyltransferase [Streptomyces
coelicolor A3(2)]
emb|CAB77330.1| (AL160331) putative tRNA/rRNA methyltransferase [Streptomyces
coelicolor A3(2)]
Length = 314
Score = 59.7 bits (143), Expect = 2e-08
Identities = 46/205 (22%), Positives = 93/205 (44%), Gaps = 10/205 (4%)
Query: 29 KEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVEL-------PLAVSLKEV 81
+ + + L A ++ N+++ + + G NHQG++ +V L + +
Sbjct: 102 ERVREALQLAAERGGINLMEAPRPELDRMTNGLNHQGLVLQVPPYEYAHPEDLVAAAHDE 161
Query: 82 KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYE-GIVRSSLGLMYDLPF 140
++ L G+TD N+G + RS G GV++ + G ++S G P
Sbjct: 162 GIDPLIVALDGVTDPRNLGAVVRSVSAFGGHGVVVPERRAAGMTAGAWKTSAGTAARTPV 221
Query: 141 SVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKK--CALFLGSEHEGLSKKILAKM 198
+ N + + + +G +G + G +++ +L+ + +GSE +GLS+ +
Sbjct: 222 ARATNLTRALEQYQKAGITVVGLAADGEAELGDLAALDGPVVIVVGSEGKGLSRLVGETC 281
Query: 199 DTILSVKMRRDFDSLNVSVAAGILM 223
D + + M +SLN VAAGI++
Sbjct: 282 DFRVRIPMPGGAESLNAGVAAGIVL 306
>ref|NP_638511.1| (NC_003902) tRNA/rRNA methyltransferase [Xanthomonas campestris pv.
campestris str. ATCC 33913]
gb|AAM42435.1| (AE012432) tRNA/rRNA methyltransferase [Xanthomonas campestris pv.
campestris str. ATCC 33913]
Length = 300
Score = 59.7 bits (143), Expect = 2e-08
Identities = 57/228 (25%), Positives = 102/228 (44%), Gaps = 12/228 (5%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACP----NIIKVDNKKAQSLAKG 60
+YG I + + + L++IYL+ E F AL C V+ LA
Sbjct: 61 LYGINAIQAVFKARPQALRKIYLT-EARIPQFKALLAWCVAQRLGYRVVEEADLTKLASS 119
Query: 61 GNHQGVLAKV----ELPLAVSLKEVKKAQKL-LVLCGITDVGNIGGIFRSAYCLGMGGVI 115
+H+G++A+V PL L + + L L L G+ + N G I RS+ G+ G++
Sbjct: 120 THHEGIVAEVLRVPPQPLQDWLAALPQGPVLALWLDGVGNPHNFGAILRSSAHFGVAGLL 179
Query: 116 LDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENL 174
L L G R + G +P +P+ + +L+ +GF + G +
Sbjct: 180 LPAGSTLGLSGAAARVAEGGAEAVPLVQLPDNAQAMAQLRQAGFAVAATLVDGGQDVFAT 239
Query: 175 SLKKCALF-LGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGI 221
+L + ++ +G+E EG+ ++ + D LS+ +SLNV+ A +
Sbjct: 240 ALPQRLVYVMGAESEGMDRQFASACDLQLSIHGSGLVESLNVASATAV 287
>ref|NP_218096.1| (NC_000962) hypothetical protein Rv3579c [Mycobacterium
tuberculosis H37Rv]
pir||A70607 hypothetical protein Rv3579c - Mycobacterium tuberculosis (strain
H37RV)
emb|CAB07153.1| (Z92774) hypothetical protein Rv3579c [Mycobacterium tuberculosis
H37Rv]
Length = 322
Score = 58.9 bits (141), Expect = 4e-08
Identities = 50/215 (23%), Positives = 97/215 (44%), Gaps = 15/215 (6%)
Query: 25 IYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAKGGNHQGVLAKV--------ELP 73
+ L E D++L + +A + I+++ + HQG+ +V +
Sbjct: 91 VALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDL 150
Query: 74 LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSL 132
LA +L + L+ L ++D N+G I RS G GV++ + + + R+S
Sbjct: 151 LAAALDQPPAL--LVALDNLSDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSA 208
Query: 133 GLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS-LKKCALFLGSEHEGLS 191
G +P + N + G +G G + ++++ + +GSE +GLS
Sbjct: 209 GAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLS 268
Query: 192 KKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ + D ++S+ M +SLN SVAAG+++ +I
Sbjct: 269 RLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAEI 303
>ref|NP_338229.1| (NC_002755) spoU rRNA methylase family protein [Mycobacterium
tuberculosis CDC1551]
gb|AAK48043.1| (AE007169) spoU rRNA methylase family protein [Mycobacterium
tuberculosis CDC1551]
Length = 253
Score = 58.9 bits (141), Expect = 4e-08
Identities = 50/215 (23%), Positives = 97/215 (44%), Gaps = 15/215 (6%)
Query: 25 IYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAKGGNHQGVLAKV--------ELP 73
+ L E D++L + +A + I+++ + HQG+ +V +
Sbjct: 22 VALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDL 81
Query: 74 LAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSL 132
LA +L + L+ L ++D N+G I RS G GV++ + + + R+S
Sbjct: 82 LAAALDQPPAL--LVALDNLSDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSA 139
Query: 133 GLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLS-LKKCALFLGSEHEGLS 191
G +P + N + G +G G + ++++ + +GSE +GLS
Sbjct: 140 GAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLS 199
Query: 192 KKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+ + D ++S+ M +SLN SVAAG+++ +I
Sbjct: 200 RLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAEI 234
>sp|P52391|NHS_STRAS 23S RRNA METHYLTRANSFERASE (23S RRNA METHYLASE)
pir||JQ0686 nosiheptide resistance protein - Streptomyces actuosus
gb|AAB17875.1| (U75434) 23S rRNA methyltransferase [Streptomyces actuosus]
Length = 274
Score = 58.2 bits (139), Expect = 7e-08
Identities = 49/181 (27%), Positives = 85/181 (46%), Gaps = 8/181 (4%)
Query: 49 VDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV-KKAQKLLVLCGITDVGNIGGIFRSAY 107
+D L K V +P L ++ ++ ++VL G+ VGNIG I R++
Sbjct: 79 IDVSIVNQLFKAERKAKVFGIARVPRPARLADIAERGGDVVVLDGVKIVGNIGAIVRTSL 138
Query: 108 CLGMGGVIL---DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGAS 164
LG G++L D A +A ++R+S G ++ LP V+ + + ++ L+ + +
Sbjct: 139 ALGAAGIVLVDSDLA-TIADRRLLRASRGYVFSLPV-VLADREEAVSFLRDNDIALMVLD 196
Query: 165 MQGSSQIENLS--LKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGIL 222
G +++L + AL GSE G S +S+ M +SLNVSV+ GI
Sbjct: 197 TDGDLGVKDLGDRADRMALVFGSEKGGPSGLFQEASAGTVSIPMLSSTESLNVSVSVGIA 256
Query: 223 M 223
+
Sbjct: 257 L 257
>ref|NP_384496.1| (NC_003047) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
emb|CAC41827.1| (AL591783) PUTATIVE TRNA/RRNA METHYLTRANSFERASE PROTEIN
[Sinorhizobium meliloti]
Length = 288
Score = 57.8 bits (138), Expect = 9e-08
Identities = 44/184 (23%), Positives = 90/184 (48%), Gaps = 9/184 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV--KKAQKLLVLCGITDVGNIGGIF 103
+++V+ K ++ + N Q V+ E + L+++ ++ + + L + D GN+G I
Sbjct: 94 VLEVNEKVISTITRRDNPQMVVGIFEQRYS-PLRDIHPQEGETYVALDRVRDPGNLGTII 152
Query: 104 RSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G G+IL + + E VR+++G ++ +P + NT D I + +G +
Sbjct: 153 RTADAAGASGIILVGETTDPFSLE-TVRATMGSVFAIPIA-RANTEDFIRWQRAAGVQVV 210
Query: 162 GASMQGSSQIENLSLKK--CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
+ GS + K L +G+E GL ++ + + + DSLN+++A
Sbjct: 211 ATHLAGSVDYRTIDYKSKPVVLLMGNEQAGLPVELAREAGALARIPQAGRADSLNLAIAT 270
Query: 220 GILM 223
GI++
Sbjct: 271 GIML 274
>gb|AAK14417.1|AC087851_9 (AC087851) putative RNA methyltransferases [Oryza sativa]
Length = 329
Score = 57.4 bits (137), Expect = 1e-07
Identities = 50/153 (32%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 84 AQKLLVLCGITDVGNIGGIFRSAYCLGMGGV-ILDFAKELAYEGIVRSSLGLMYDLPFSV 142
A+++LVL GI D GN+G + RSA GV +L + E +R++ G LP V
Sbjct: 166 AKRILVLDGIQDPGNLGTLIRSACAFRWDGVFLLPACCDPFNEKALRAARGASLQLPV-V 224
Query: 143 MPNTLDLINELKTSGFLCLGASMQGSSQ------------IENLSLKKCALFLGSEHEGL 190
N DL + S L + SS ++L + L LGSE GL
Sbjct: 225 SGNWSDLHALMAKSDMKMLAGHPESSSNGSERTHVLSKELADSLMSESVCLVLGSEGNGL 284
Query: 191 SKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
S L + ++++ M+ F+SLNVSVA GI +
Sbjct: 285 SADTLQACE-LVNIPMQGTFESLNVSVAGGIFL 316
>ref|NP_499333.1| (NM_066932) SpoU rRNA Methylase family [Caenorhabditis elegans]
pir||T26946 hypothetical protein Y45F3A.9 - Caenorhabditis elegans
emb|CAA21494.1| (AL032621) contains similarity to Pfam domain: PF00588 (SpoU rRNA
Methylase family), Score=78.1, E-value=6e-20, N=1~cDNA
EST yk116a2.3 comes from this gene [Caenorhabditis
elegans]
Length = 294
Score = 57.0 bits (136), Expect = 2e-07
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 15/150 (10%)
Query: 93 ITDVGNIGGIFRSAYCLGMGGVILDFAK--ELAYEGIVRSSLGLMYDLPFSVMPNTLDLI 150
+ D GN+G I RSA+ G G+ L + + +++SS G + LP N +
Sbjct: 139 VLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFR 198
Query: 151 NELKTSGFLCLGASMQGSSQIENLSLKKC---------ALFLGSEHEGLSKKILAKMDTI 201
+++K +G + G+++ +S K + LG E G+S+ IL DT+
Sbjct: 199 DKIKAAGGELVATCDPGAAEKAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTV 258
Query: 202 LSVK-MRRD---FDSLNVSVAAGILMDKIN 227
+S+ +R+D SLNVSV AGIL+ I+
Sbjct: 259 ISISPVRKDGSNVTSLNVSVVAGILLHHIS 288
>ref|NP_104368.1| (NC_002678) rRNA methylase [Mesorhizobium loti]
dbj|BAB50154.1| (AP003001) rRNA methylase [Mesorhizobium loti]
Length = 274
Score = 56.2 bits (134), Expect = 3e-07
Identities = 47/187 (25%), Positives = 91/187 (48%), Gaps = 9/187 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVK--KAQKLLVLCGITDVGNIGGIF 103
+++V K ++ + N Q V+ ++LK+++ + L + D GN+G +
Sbjct: 77 VLEVSEKVLVAITRRDNPQMVVGVFSQKF-LALKDIRADNGDVWVALDRVRDPGNLGTVI 135
Query: 104 RSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+ +G GVIL D + E VR+++G ++ +P + L SG L
Sbjct: 136 RTVDAVGAKGVILVGDTTDPFSVE-TVRATMGSIFAVPVAKATTEAFLAWRGGFSG-LVA 193
Query: 162 GASMQGSSQIENLSLKK--CALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
G ++G+ ++ + L +G+E +GL + + A D +L + DSLN++VA
Sbjct: 194 GTHLKGAVDYRSVDFSRGPVLLMMGNEQQGLPESLAASCDRLLRIPQAGRADSLNLAVAT 253
Query: 220 GILMDKI 226
GI++ +I
Sbjct: 254 GIMLFEI 260
>ref|NP_457123.1| (NC_003198) putative RNA methyltransferase [Salmonella enterica
subsp. enterica serovar Typhi]
ref|NP_461583.1| (NC_003197) putative tRNA/rRNA methyltransferase [Salmonella
typhimurium LT2]
gb|AAL21542.1| (AE008820) putative tRNA/rRNA methyltransferase [Salmonella
typhimurium LT2]
emb|CAD05832.1| (AL627276) putative RNA methyltransferase [Salmonella enterica
subsp. enterica serovar Typhi]
Length = 345
Score = 56.2 bits (134), Expect = 3e-07
Identities = 51/227 (22%), Positives = 101/227 (44%), Gaps = 8/227 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGG--- 61
+YG+ L S + + + + + + AL+ N LAK
Sbjct: 110 VYGENACQALFQSRPDAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELAKASGTE 169
Query: 62 NHQGVLAKVELPLAVSLKE-VKKAQKLLVLCGITDVGN---IGGIFRSAYCLGMGGVILD 117
+H GV ++ ++K+ VK+A + + DV N +GG+ RS G+ GV++
Sbjct: 170 HHGGVCFLIKKRNGTTVKQWVKQAADQDCVLALEDVANPHNLGGMMRSCAHFGVKGVVVQ 229
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSL- 176
A L +R++ G + + +D++++ + +G+ + S + + +L
Sbjct: 230 DAALLESGAAIRTAEGGAEHVQPITGESIVDVLDDFRQAGYTVVTTSSDRGQALFSTTLP 289
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+K L LG E++ L + D + + + +SLNVSVA G+L+
Sbjct: 290 EKMVLVLGREYDYLPEAAREPDDLCVKINGTGNVESLNVSVATGVLL 336
>ref|NP_540715.1| (NC_003317) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
gb|AAL52979.1| (AE009612) 23S ribosomal RNA methyltransferase [Brucella
melitensis]
Length = 297
Score = 56.2 bits (134), Expect = 3e-07
Identities = 37/138 (26%), Positives = 69/138 (49%), Gaps = 6/138 (4%)
Query: 93 ITDVGNIGGIFRSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLI 150
+ D GN+G + R+A +G GVIL D + E VR+++G ++ +P + D +
Sbjct: 151 VRDPGNLGAVIRTADAVGAKGVILIGDTTDPYSLE-TVRATMGSVFSVPL-YRASEADFL 208
Query: 151 NELKTSGFLCLGASMQGSSQIENLSL--KKCALFLGSEHEGLSKKILAKMDTILSVKMRR 208
N K L +G ++G+ + K L +G+E +GL + D + +
Sbjct: 209 NWRKGFSGLVVGTHLKGAVDYRTIPYANKPVILIMGNEQQGLPDSLAGACDKLARIPQAG 268
Query: 209 DFDSLNVSVAAGILMDKI 226
DSLN+++A G+++ +I
Sbjct: 269 RADSLNLAIATGVMLYEI 286
>ref|NP_531047.1| (NC_003304) rRNA methylase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
gb|AAL41363.1| (AE009005) rRNA methylase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
Length = 282
Score = 55.8 bits (133), Expect = 3e-07
Identities = 44/184 (23%), Positives = 88/184 (46%), Gaps = 9/184 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVK--KAQKLLVLCGITDVGNIGGIF 103
+++V K S+ + N Q V+ E LK+++ K + + L + D GN+G I
Sbjct: 88 VLEVSEKVIASITRRDNPQMVVGIFEQKWK-PLKDIRPEKGETYIALDRVRDPGNLGTII 146
Query: 104 RSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G GVIL D + E VR+++G ++ P + + + ++ K++ +
Sbjct: 147 RTADAAGASGVILVGDCTDPFSLE-TVRATMGSVFATPVA-RASVEEFLSWKKSAHVSVV 204
Query: 162 GASMQGSSQIENLSL--KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
+ GS + K + +G+E GL ++ K D + + + DSLN+++A
Sbjct: 205 ATHLAGSVDYRKIDYAGKPVVILMGNEQSGLPPELAGKADQLARIPQQGRADSLNLAIAT 264
Query: 220 GILM 223
+++
Sbjct: 265 AVML 268
>ref|NP_072917.1| (NC_000908) rRNA methylase, putative [Mycoplasma genitalium]
sp|P47494|Y252_MYCGE Hypothetical tRNA/rRNA methyltransferase MG252
pir||H64227 rRNA methylase - Mycoplasma genitalium
gb|AAC71472.1| (U39704) rRNA methylase, putative [Mycoplasma genitalium]
Length = 242
Score = 55.8 bits (133), Expect = 3e-07
Identities = 45/173 (26%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Query: 62 NHQGVLAKVE-----LPL--AVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
NHQ ++A ++ +PL V + E KK L++L I D N G I R+ + G+
Sbjct: 65 NHQELVAVLDTNQLLIPLDQLVKVVENKKCSTLVMLDEIQDPYNFGAILRTCLASEVDGI 124
Query: 115 ILDFAKELAYEG-IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQG---SSQ 170
I ++ ++++S+G ++ + N I +LK GF + +++
Sbjct: 125 IFKKNNQVPINNTVMKTSMGSVFYQNLVQVANLSYTITKLKEIGFWTVVSTLDPIWKPID 184
Query: 171 IENLSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ K L +G+E G+++ I D + + M +SLNVSVA GI++
Sbjct: 185 YRKVDFAKKILIVGNEDRGVNQLITKNADCRIKIPMNNKINSLNVSVALGIIL 237
>ref|NP_353372.1| (NC_003062) AGR_C_593p [Agrobacterium tumefaciens] [Agrobacterium
tumefaciens str. C58 (Cereon)]
gb|AAK86157.1| (AE007972) AGR_C_593p [Agrobacterium tumefaciens str. C58 (Cereon)]
Length = 290
Score = 55.8 bits (133), Expect = 3e-07
Identities = 44/184 (23%), Positives = 88/184 (46%), Gaps = 9/184 (4%)
Query: 46 IIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVK--KAQKLLVLCGITDVGNIGGIF 103
+++V K S+ + N Q V+ E LK+++ K + + L + D GN+G I
Sbjct: 96 VLEVSEKVIASITRRDNPQMVVGIFEQKWK-PLKDIRPEKGETYIALDRVRDPGNLGTII 154
Query: 104 RSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G GVIL D + E VR+++G ++ P + + + ++ K++ +
Sbjct: 155 RTADAAGASGVILVGDCTDPFSLE-TVRATMGSVFATPVA-RASVEEFLSWKKSAHVSVV 212
Query: 162 GASMQGSSQIENLSL--KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAA 219
+ GS + K + +G+E GL ++ K D + + + DSLN+++A
Sbjct: 213 ATHLAGSVDYRKIDYAGKPVVILMGNEQSGLPPELAGKADQLARIPQQGRADSLNLAIAT 272
Query: 220 GILM 223
+++
Sbjct: 273 AVML 276
>ref|NP_406739.1| (NC_003143) putative tRNA/rRNA methyltransferase [Yersinia pestis]
emb|CAC92503.1| (AJ414156) putative tRNA/rRNA methyltransferase [Yersinia pestis]
Length = 388
Score = 55.5 bits (132), Expect = 5e-07
Identities = 55/228 (24%), Positives = 97/228 (42%), Gaps = 9/228 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGG--- 61
+YG+ L S + + + + + + ALK N + LAK
Sbjct: 150 VYGENACKALFESRPDAIVRAWFVQSVTPRFREALKWMAANRKAYHVVEEDELAKASGTE 209
Query: 62 NHQGVLAKVE----LPLAVSLKEVKKAQK-LLVLCGITDVGNIGGIFRSAYCLGMGGVIL 116
+H GV ++ L L++ +A+ +L L + + N+GGI R+ G+ GV+L
Sbjct: 210 HHGGVCFLIKKRQGLDAETYLQQQTQAKDCVLALEEVGNPHNLGGIMRTCAHFGINGVLL 269
Query: 117 DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSL 176
L VR++ G + + L +++ + +G+ + S + L
Sbjct: 270 QDPAMLESGAAVRTAEGGAEHIKAINADDFLSVLDTFRKAGYTIVTTSSHKGVSLSKAEL 329
Query: 177 K-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K L LG E +GL+ + D +S+ +SLNVSVA GIL+
Sbjct: 330 PAKMVLVLGQESDGLTDSAWQQGDLSVSIGGTGRVESLNVSVATGILL 377
>ref|NP_195515.1| (NM_119963) hypothetical protein [Arabidopsis thaliana]
pir||T05629 hypothetical protein F20D10.140 - Arabidopsis thaliana
emb|CAB37542.1| (AL035538) hypothetical protein [Arabidopsis thaliana]
emb|CAB80467.1| (AL161592) hypothetical protein [Arabidopsis thaliana]
Length = 400
Score = 55.5 bits (132), Expect = 5e-07
Identities = 51/154 (33%), Positives = 77/154 (49%), Gaps = 17/154 (11%)
Query: 84 AQKLLVLCGITDVGNIGGIFRSAYCLGMGGV-ILDFAKELAYEGIVRSSLGLMYDLPF-S 141
A ++LVL I D GN+G + RSA G +L + + +R+S G + LP S
Sbjct: 243 AHRVLVLDSIQDPGNLGTLVRSAMAFNWDGAFLLPGCCDPYNDKALRASRGASFQLPIVS 302
Query: 142 VMPNTLDLI-NELKTSGFLCLGASMQGSSQI-----------ENLSLKKCALFLGSEHEG 189
N L L+ NE + L G + ++ ++L+ K L LGSE G
Sbjct: 303 GNWNHLKLLENEFQMK--LLAGHPATTTQKLKPVSKLSVEFAQSLAEKPLCLILGSEGNG 360
Query: 190 LSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
LS++ K+ ++S+ M DF+SLNVSVA GI +
Sbjct: 361 LSEQA-RKVCVLVSIPMAGDFESLNVSVAGGIFL 393
>gb|EAA03105.1| (AAAB01007848) ebiP2005 [Anopheles gambiae str. PEST]
Length = 162
Score = 55.1 bits (131), Expect = 6e-07
Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 5/152 (3%)
Query: 77 SLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLM 135
+ K+ +K +++L I + N+G +FR+A + V+L + + I +++LG
Sbjct: 9 TFKQSEKIPVIVLLDSIRSMNNVGAVFRTADAFIIEKVVLCGITPQPPHREIHKAALGAT 68
Query: 136 YDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSL----KKCALFLGSEHEGLS 191
+ + + + + +LK+ G+ L S N + KK + +G+E +G+S
Sbjct: 69 ESVDWYYEKDVTEALQKLKSEGYKILAIEQTTGSIALNEQVISKDKKYVVIMGNEVDGVS 128
Query: 192 KKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ LA D + + SLNVSV AGI+M
Sbjct: 129 DEALALCDGFIEIPQLGTKHSLNVSVCAGIIM 160
>ref|NP_600607.1| (NC_003450) COG0566:rRNA methylases [Corynebacterium glutamicum]
Length = 273
Score = 55.1 bits (131), Expect = 6e-07
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 8/133 (6%)
Query: 97 GNIGGIFRSAYCLGMGGVILDFAKELAYE---GIVRSSLGLMYDLPFSVMPNTLDLINEL 153
GN G + R + +G V+ FA E VRSS G ++ +P + N D++ +L
Sbjct: 132 GNAGTLIRVSDAVGADAVV--FAGESVDPLGAKAVRSSAGSLFHIPVARNNNIADVLGQL 189
Query: 154 KTSGFLCLGASMQGSSQIEN---LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDF 210
++ G L S G +++ L K A G+E GL + +LA+ D + + +R
Sbjct: 190 RSKGLQILATSADGEVDLDDADELLAKPTAWLFGNEAHGLDESLLAQADHRVRIPIRGRA 249
Query: 211 DSLNVSVAAGILM 223
+SLN++ AA I +
Sbjct: 250 ESLNLATAASICL 262
>ref|NP_197043.1| (NM_121543) rRNA methylase - like protein [Arabidopsis thaliana]
pir||T49974 rRNA methylase-like protein - Arabidopsis thaliana
emb|CAB89349.1| (AL353993) rRNA methylase-like protein [Arabidopsis thaliana]
Length = 350
Score = 55.1 bits (131), Expect = 6e-07
Identities = 44/140 (31%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Query: 88 LVLCGITDVGNIGGIFRSAYCLGMGGV-ILDFAKELAYEGIVRSSLGLMYDLPFSVMPNT 146
LV+ G++D GNI FRSA LG+ V ++ Y G S+G L
Sbjct: 157 LVVEGLSDFGNISAAFRSADALGIQSVHVVSCDSSKRYNGNRHVSMGAEKWLDIEFWDTP 216
Query: 147 LDLINELKTSGFLCLGASMQGSSQIENLSLK---KCALFLGSEHEGLSKKILAKMDTILS 203
+ LK+ G+ + + G + + A+ +G+E G+S + L D S
Sbjct: 217 KECFKVLKSRGYR-IATTHLGMDTVSIYDMDWSCPTAIVVGNEGRGISDEALELSDLRCS 275
Query: 204 VKMRRDFDSLNVSVAAGILM 223
+ M DS NVSVAAGILM
Sbjct: 276 IPMNGMVDSFNVSVAAGILM 295
>dbj|BAB98781.1| (AP005278) rRNA methylases [Corynebacterium glutamicum ATCC 13032]
Length = 198
Score = 55.1 bits (131), Expect = 6e-07
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 8/133 (6%)
Query: 97 GNIGGIFRSAYCLGMGGVILDFAKELAYE---GIVRSSLGLMYDLPFSVMPNTLDLINEL 153
GN G + R + +G V+ FA E VRSS G ++ +P + N D++ +L
Sbjct: 57 GNAGTLIRVSDAVGADAVV--FAGESVDPLGAKAVRSSAGSLFHIPVARNNNIADVLGQL 114
Query: 154 KTSGFLCLGASMQGSSQIEN---LSLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDF 210
++ G L S G +++ L K A G+E GL + +LA+ D + + +R
Sbjct: 115 RSKGLQILATSADGEVDLDDADELLAKPTAWLFGNEAHGLDESLLAQADHRVRIPIRGRA 174
Query: 211 DSLNVSVAAGILM 223
+SLN++ AA I +
Sbjct: 175 ESLNLATAASICL 187
>gb|AAM28546.1|AF494517_1 (AF494517) putative tRNA/rRNA methyl transferase [Tomato big bud
phytoplasma]
Length = 210
Score = 54.3 bits (129), Expect = 1e-06
Identities = 45/176 (25%), Positives = 86/176 (48%), Gaps = 9/176 (5%)
Query: 55 QSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV 114
+SL K N+ +L ++ + LK + K+L+L I D N G + RSA G +
Sbjct: 23 KSLMKALNNNHILYS-QVAICKMLKFSGFSDKILILDDIQDPSNAGLLLRSACAFGFKNI 81
Query: 115 IL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIEN 173
+ + ++ E ++ S G +++L F + + ++ LK + + +G ++ + N
Sbjct: 82 FFSNNSVDIYNEKTIQVSQGAIFNLDF-FRGDLANFLSFLKKNDYFVIGTCGHENNFLSN 140
Query: 174 LSLKKC------ALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ C AL LG+E +G+S K D ++++ +SLNV+VA I+M
Sbjct: 141 NLINICSKYYKIALILGNEGQGISVISRQKSDYLIAIPTTNLVESLNVAVAGSIIM 196
>ref|NP_110043.1| (NC_000912) tRNA/rRNA methyltransferase [Mycoplasma pneumoniae]
sp|P75424|Y252_MYCPN Hypothetical tRNA/rRNA methyltransferase MG252 homolog
(H91_orf242a)
pir||S73807 hypothetical protein yacO - Mycoplasma pneumoniae (strain ATCC
29342)
gb|AAB96129.1| (AE000047) tRNA/rRNA methyltransferase (fragment?)~MPN355(new),
482(Himmelreich et al., 1996) [Mycoplasma pneumoniae]
Length = 242
Score = 53.9 bits (128), Expect = 1e-06
Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 4/152 (2%)
Query: 76 VSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEG-IVRSSLGL 134
+ + + K L++L I D N G I R+ + G+I + ++R+S+G
Sbjct: 86 IQITDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGT 145
Query: 135 MYDLPFSVMPNTLDLINELKTSGFLCLGASMQGS---SQIENLSLKKCALFLGSEHEGLS 191
++ + N I L+ GF + ++ + K L +G+E +GL+
Sbjct: 146 VFYQNLVQVTNLSYAITTLQKHGFWTVATTLDERLKPKDYRQVDFDKRILLVGNEDKGLN 205
Query: 192 KKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+L D + + M +SLNVSVA GI++
Sbjct: 206 ALLLKNADLKVKIPMNPKLNSLNVSVAVGIIL 237
>ref|NP_294741.1| (NC_001263) rRNA methylase [Deinococcus radiodurans]
pir||A75448 rRNA methylase - Deinococcus radiodurans (strain R1)
gb|AAF10591.1|AE001953_5 (AE001953) rRNA methylase [Deinococcus radiodurans]
Length = 265
Score = 53.9 bits (128), Expect = 1e-06
Identities = 48/164 (29%), Positives = 76/164 (46%), Gaps = 5/164 (3%)
Query: 62 NHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGV-ILDFAK 120
N GVL LP A L + ++VL G+ GN+G I R+A G GV +L
Sbjct: 93 NPDGVLGVAPLP-APRLPQPGDDTVVVVLHGLEKPGNVGAILRTADAAGAAGVLVLGRGA 151
Query: 121 ELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLK-KC 179
+ ++R+S G ++ +P +V+ L L F + + + + L +
Sbjct: 152 DPYGPNVIRASQGAVFSVPTAVLGEDAAL-GWLAEHNFRTVACTPDAPADYWDTPLTGRV 210
Query: 180 ALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
AL LG+EH GL + A + V M DSLNV+ AA +++
Sbjct: 211 ALLLGTEHAGLPAEWRAAHQAV-RVPMHGQADSLNVATAAALVL 253
>ref|NP_473099.1| (NC_000910) rRNA methylase (SpoU family) (OO, TP) [Plasmodium
falciparum]
pir||B71604 rRNA methylase (SpoU family) (OO, TP) PFB0855c - malaria parasite
(Plasmodium falciparum)
gb|AAC71960.1| (AE001421) rRNA methylase (SpoU family) (OO, TP) [Plasmodium
falciparum 3D7]
Length = 351
Score = 53.5 bits (127), Expect = 2e-06
Identities = 62/260 (23%), Positives = 110/260 (41%), Gaps = 40/260 (15%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIY---LSKEIDKK----LFFALKKACPNIIKVDNKKAQSL 57
IYG + +L ++ ++E+ L+++I K+ +F LKK +I ++ K L
Sbjct: 87 IYGLNSVYAVLKKNERTIEEVINIKLNRKIHKQNYEYIFDELKKRNVSIQYMEKYKMNEL 146
Query: 58 AKGGNHQGVLAKVELPLAVSLKEVKKAQK--------LLVLCGITDVGNIGGIFRSAYCL 109
G H ++ K + K+ K K + L + D NIG + RS +
Sbjct: 147 VGGFPHNDIIMKTHYRYMNNYKDFIKNIKHLPNKNNIFICLHDVYDNMNIGNVCRSIFFF 206
Query: 110 GMGGVILDFAKELAYEG--------IVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
G + L K++ + I+ SS+G L F + N + +N +K +GF
Sbjct: 207 GGHTIFLKKKKKVNEKKNNVKIDTPILHSSVGSSEFLNFYHINNMANFMNHMKLNGFTIY 266
Query: 162 GASMQGSS-------QIENLSLK---KCALFLGSEHEGLSKKILAKMD-----TILSVKM 206
S ++ + N+ ++ K + LG+E +GL + IL D LS
Sbjct: 267 STSCHKNNTSCHKYINLNNIKIRENEKILIILGNESKGLKEDILENSDYCVYINNLSYNE 326
Query: 207 RRDF--DSLNVSVAAGILMD 224
F DSLNV+ I+++
Sbjct: 327 NTQFHIDSLNVNNVCSIMLN 346
>ref|NP_219913.1| (NC_000117) rRNA Methylase (SpoU family) [Chlamydia trachomatis]
pir||F71519 probable rRNA methylase - Chlamydia trachomatis (serotype D, strain
UW3/Cx)
gb|AAC68000.1| (AE001313) rRNA Methylase (SpoU family) [Chlamydia trachomatis]
Length = 269
Score = 53.5 bits (127), Expect = 2e-06
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 22/198 (11%)
Query: 22 LQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV 81
++++Y SK+I +KL F K+ N I V KK S + G+ K + P + +++
Sbjct: 71 IEKLYCSKDILEKLSF--KENPENFIAVFEKKELSCQE---FLGLQRKNQAPFYLIVEQA 125
Query: 82 KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPF 140
+K GNIG + R A G+ GVIL D +L ++RSSLG ++ +P
Sbjct: 126 EKP------------GNIGALLRIADGAGVDGVILCDPVVDLYNPNVIRSSLGTVFTMPV 173
Query: 141 --SVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCALFLGSEHEGLSKKILAKM 198
+ + LDL+++ + F ++ + + + + GSE +GLS L
Sbjct: 174 WQASLKEVLDLVHQQEWQVFTTTPSAQ--TFYFDQDFCQPMVVVFGSEKDGLSPDWLNGS 231
Query: 199 DTILSVKMRRDFDSLNVS 216
+++ M DSLN+S
Sbjct: 232 FCNIALPMLGKADSLNLS 249
>ref|NP_603772.1| (NC_003454) 23S rRNA methyltransferase [Fusobacterium nucleatum
subsp. nucleatum ATCC 25586]
gb|AAL95071.1| (AE010596) 23S rRNA methyltransferase [Fusobacterium nucleatum
subsp. nucleatum ATCC 25586]
Length = 261
Score = 52.8 bits (125), Expect = 3e-06
Identities = 49/189 (25%), Positives = 94/189 (48%), Gaps = 8/189 (4%)
Query: 40 KKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNI 99
K +C I+ V K + L+ N QG++ LK + + L++L ++D GN+
Sbjct: 70 KFSCKEIV-VTRKIFEELSSQENSQGIIILYNKKTN-DLKFL--SNNLVILDDVSDPGNL 125
Query: 100 GGIFRSAYCLGMGGVILDFAKELAY-EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGF 158
G I R +IL AY E ++R+++G + ++ + + ++IN LK + +
Sbjct: 126 GTIIRICDATNFKDIILTKGTVDAYNEKVIRATMGSILNVNLYYLEKS-EIINFLKENNY 184
Query: 159 LCLGASMQGSSQIEN-LSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVS 216
+ + ++ + N + LK K A+ G+E G+S + D + + + +SLNV+
Sbjct: 185 SIISTYLDKTAILYNKIELKEKNAVIFGNEGNGISDDFINITDYKTIIPILSNTESLNVA 244
Query: 217 VAAGILMDK 225
VA GI++ K
Sbjct: 245 VATGIILYK 253
>ref|NP_230452.1| (NC_002505) RNA methyltransferase, TrmH family [Vibrio cholerae]
pir||E82278 RNA methyltransferase, TrmH family VC0803 [imported] - Vibrio
cholerae (group O1 strain N16961)
gb|AAF93967.1| (AE004165) RNA methyltransferase, TrmH family [Vibrio cholerae]
Length = 257
Score = 52.8 bits (125), Expect = 3e-06
Identities = 57/225 (25%), Positives = 104/225 (45%), Gaps = 13/225 (5%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKK-ACPNIIKVDNKKAQSLAKGGN 62
++ G++ ++ L NS K+Q I+ + E + AL C D K +L +
Sbjct: 39 LVQGEKNVLELTNSTL-KVQHIFATAEFLAEHAQALAGFECIEATLDDLTKVSTLV---S 94
Query: 63 HQGVLAKVELPLAVSLKEVKKAQKLLV-LCGITDVGNIGGIFRSAYCLGMGGVILDFAKE 121
+ +A V +P EV KAQ L++ L G++D GN+G I R A G+ +I A +
Sbjct: 95 NNAAIAVVAIPHI----EVPKAQGLMIALDGVSDPGNLGTIIRVADWYGISHII---ASQ 147
Query: 122 LAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCAL 181
+ ++ V + +DL + L + GA ++G S + + L
Sbjct: 148 DCADPYNPKTISATMGSFGRVQVSQVDLPDYLAKANLPVYGAFLEGVSVHQTAFQAEGIL 207
Query: 182 FLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
+GSE G+ ++ + +++ +SLNV++A GI++D I
Sbjct: 208 LMGSESHGIREQAAQYVTDKITIPAFGGAESLNVAMATGIILDNI 252
>ref|NP_311474.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
ref|NP_417076.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
sp|P33635|YFIF_ECOLI Hypothetical tRNA/rRNA methyltransferase yfiF
pir||D65036 hypothetical 37.8 kD protein in ung 3' region - Escherichia coli
(strain K-12)
gb|AAC75634.1| (AE000344) orf, hypothetical protein [Escherichia coli K12]
dbj|BAB36870.1| (AP002562) hypothetical protein [Escherichia coli O157:H7]
Length = 345
Score = 52.4 bits (124), Expect = 4e-06
Identities = 50/227 (22%), Positives = 99/227 (43%), Gaps = 8/227 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAKGG 61
+YG+ L S E + + + + + AL+ N VD + +
Sbjct: 110 VYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTE 169
Query: 62 NHQGVLAKVELPLAVSLKE-VKKAQK---LLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
+H GV ++ ++++ V +A +L L ++ N+GG+ RS G+ GV++
Sbjct: 170 HHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQ 229
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLK 177
A L +R++ G + N ++++++ + +G+ + S + + SL
Sbjct: 230 DAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLP 289
Query: 178 -KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K L LG E+EGL D + + + LN+SVA G+L+
Sbjct: 290 AKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLL 336
>ref|NP_289139.1| (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
gb|AAG57697.1|AE005488_8 (AE005488) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
Length = 345
Score = 52.0 bits (123), Expect = 5e-06
Identities = 50/227 (22%), Positives = 98/227 (43%), Gaps = 8/227 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAKGG 61
+YG+ L S E + + + + + AL+ N VD + +
Sbjct: 110 VYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAXHVVDEAELTKASGTE 169
Query: 62 NHQGVLAKVELPLAVSLKE-VKKAQK---LLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
+H GV ++ ++++ V +A +L L + N+GG+ RS G+ GV++
Sbjct: 170 HHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENEXNPHNLGGMMRSCAHFGVKGVVVQ 229
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLK 177
A L +R++ G + N ++++++ + +G+ + S + + SL
Sbjct: 230 DAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLP 289
Query: 178 -KCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
K L LG E+EGL D + + + LN+SVA G+L+
Sbjct: 290 AKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLL 336
>ref|NP_441675.1| (NC_000911) rRNA methylase [Synechocystis sp. PCC 6803]
sp|P74261|YG73_SYNY3 Hypothetical tRNA/rRNA methyltransferase SLR1673
pir||S75896 hypothetical protein - Synechocystis sp. (strain PCC 6803)
dbj|BAA18355.1| (D90913) rRNA methylase [Synechocystis sp. PCC 6803]
Length = 274
Score = 52.0 bits (123), Expect = 5e-06
Identities = 36/138 (26%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Query: 88 LVLCGITDVGNIGGIFRSAYCLGMGGVILDF-AKELAYEGIVRSSLGLMYDLPFSVMPNT 146
LVL + D GN+G I R+A G+ G+ L + ++RSS G LP + +
Sbjct: 123 LVLERLQDPGNLGTILRTAAATGVEGIWLTADCVDPTSPKVLRSSAGSSLLLPQQQLQSL 182
Query: 147 LDLINELKTSGFLCLGASMQGSSQIENLSLKKCALFL-GSEHEGLSKKILAKMDTILSVK 205
L+ + T G + Q + + + ++ + + GSE +GLS +L +++
Sbjct: 183 PPLLEKFHTQGLQLIATVPQATQTLWEIDFQRPTIVIFGSEGQGLSAPVLELTTHQVAIP 242
Query: 206 MRRDFDSLNVSVAAGILM 223
+SLNV++A G+++
Sbjct: 243 QAPQVESLNVAIAVGVML 260
>sp|P52393|TSNR_STRLU RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE (23S RRNA [AM1067]
2'-O-METHYLTRANSFERASE) (23S RRNA METHYLASE)
(THIOSTREPTON-RESISTANCE METHYLASE)
pir||JC4350 thiostrepton - Streptomyces laurentii
gb|AAA99931.1| (L39157) rRNA methyltransferase [Streptomyces laurentii]
Length = 270
Score = 52.0 bits (123), Expect = 5e-06
Identities = 41/143 (28%), Positives = 68/143 (46%), Gaps = 5/143 (3%)
Query: 87 LLVLCGITDVGNIGGIFRSAYCLGMGGVIL--DFAKELAYEGIVRSSLGLMYDLPFSVMP 144
+++L G+ VGNIG I R+ LG G++L +A ++R+S G ++ LP V+
Sbjct: 118 VVLLDGVKIVGNIGAIVRTRSALGAAGIVLVDSGLGTIADRRLIRASRGYVFSLPI-VLA 176
Query: 145 NTLDLINELKTSGFLCLGASMQGSSQIENLSL--KKCALFLGSEHEGLSKKILAKMDTIL 202
+ + + G + G I L ++ L GSE G S + +
Sbjct: 177 TRDEALAFFRDGGMRPVVFEADGKLSIGELDGIDERLVLVFGSEKTGPSGEFAGVATESV 236
Query: 203 SVKMRRDFDSLNVSVAAGILMDK 225
S+ M +SLNVSV+AGI + +
Sbjct: 237 SIPMNPAAESLNVSVSAGIALHR 259
>ref|NP_078161.1| (NC_002162) rRNA methylase [Ureaplasma urealyticum]
pir||C82904 rRNA methylase UU327 [imported] - Ureaplasma urealyticum
gb|AAF30736.1|AE002130_3 (AE002130) rRNA methylase [Ureaplasma urealyticum]
Length = 257
Score = 51.2 bits (121), Expect = 9e-06
Identities = 36/143 (25%), Positives = 74/143 (51%), Gaps = 3/143 (2%)
Query: 87 LLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIVRSSLGLMYDLPFSVMPNT 146
+L+L I D GN+G I R+ + + VI + +L +++S+G ++ + F ++
Sbjct: 115 ILLLDNIQDPGNLGTILRTCFAFNIKQVIFNNCVDLYNPKTIKASMGAIFKINFLRFNDS 174
Query: 147 LDLINELKTSGFLCLGASM-QGSSQIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSV 204
+N L + F + + + + + +++K K L +G+E GL + + +
Sbjct: 175 KLALNFLLKNKFYLIATILDKNAISLNEITIKQKYCLMVGNEGHGLVQTFIDHAHIKTMI 234
Query: 205 KMRRDFDSLNVSVAAGILMDKIN 227
KM + +SLNV+VAA I + ++N
Sbjct: 235 KMNQT-ESLNVAVAAAIFLYELN 256
>ref|NP_484219.1| (NC_003272) rRNA methylase [Nostoc sp. PCC 7120]
dbj|BAB77699.1| (AP003581) rRNA methylase [Nostoc sp. PCC 7120]
Length = 273
Score = 51.2 bits (121), Expect = 9e-06
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 18/193 (9%)
Query: 43 CPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEVKKAQKLLVLCGITDVGNIGGI 102
C V + Q++A GV+A + S +V +L L I D GN+G I
Sbjct: 83 CDRYEIVSEEVLQAIATTVQPDGVVATAKRSEQQS--QVPFTGVVLALETIQDPGNLGTI 140
Query: 103 FRSAYCLGMGGVILDF-AKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
R+A G G++L + +L ++R+S G + L +V +LK + LC
Sbjct: 141 IRTAAAAGASGLLLSQDSVDLDNPKVLRASAGQWFRLATAVS-------EDLKATVQLCQ 193
Query: 162 GASMQGSSQIENLSL--------KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSL 213
A MQ + + L K + LG+E GLS + A D + + + +SL
Sbjct: 194 QAGMQVVATLPTAKLTYWEIDWRKPSLILLGNEGAGLSPDLAAMADQEVKIPLSPGVESL 253
Query: 214 NVSVAAGILMDKI 226
NV++ + +++ ++
Sbjct: 254 NVAITSALMLYEV 266
>ref|NP_596705.1| (NC_003423) putative ribose methyltransferase [Schizosaccharomyces
pombe]
pir||T39401 probable ribose methyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB37444.1| (AL035548) putative ribose methyltransferase [Schizosaccharomyces
pombe]
Length = 301
Score = 50.8 bits (120), Expect = 1e-05
Identities = 47/144 (32%), Positives = 67/144 (45%), Gaps = 13/144 (9%)
Query: 92 GITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLI 150
GITD N+G + RSAY LG G++L +V ++S G + S + N + +
Sbjct: 154 GITDPQNMGAVIRSAYILGAKGILLSKKHNTFLSPVVSKASAGALEVFNISHVKNPMVFL 213
Query: 151 NELKTSGFLCLG---ASMQGSSQI-------ENLSLKKCALFLGSEHEGLSKKILAKMDT 200
G+ +G A QI L + L LGSE +GL IL +
Sbjct: 214 RNSVLKGWKVIGTKPALPDNKDQIYTPHKIKTELMNEPKILVLGSE-KGLRTNILTQCSH 272
Query: 201 ILSVKMRRDF-DSLNVSVAAGILM 223
+S+ + DSLNVSVAAGIL+
Sbjct: 273 YVSIPGGDKYVDSLNVSVAAGILL 296
>gb|AAG32066.1| (AF333038) rRNA methyltransferase [Streptomyces viridochromogenes]
Length = 287
Score = 49.3 bits (116), Expect = 3e-05
Identities = 49/167 (29%), Positives = 77/167 (45%), Gaps = 10/167 (5%)
Query: 66 VLAKVELPLAVSLKEVKKAQKLL--VLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKEL 122
V+A VE+P A L + + L + T GNIG I RSA LG G+I+ A ++
Sbjct: 106 VVAVVEMP-ADDLDRIPVREDFLGVLFDRPTSPGNIGSIIRSADALGAHGLIVAGHAADV 164
Query: 123 AYEGIVRSSLGLMYDLPFSVMPN---TLDLINELKTSG--FLCLGASMQGSSQIENLSLK 177
VRSS G ++ LP +P+ +D + + +G + +G G + +
Sbjct: 165 YDPKSVRSSTGSLFSLPAVRVPSPGEVMDWVEARRAAGTPIVLVGTDEHGDCDVFDFDFT 224
Query: 178 KCALFL-GSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ L L G+E GLS D +S+ M SLN + AA ++
Sbjct: 225 QPTLLLIGNETAGLSNAWRTLCDYTVSIPMAGSASSLNAANAATAIL 271
>ref|NP_625873.1| (NC_003888) putative rRNA methylase [Streptomyces coelicolor A3(2)]
pir||T36832 probable rRNA methylase - Streptomyces coelicolor
emb|CAA20808.1| (AL031541) putative rRNA methylase [Streptomyces coelicolor A3(2)]
Length = 282
Score = 48.9 bits (115), Expect = 4e-05
Identities = 39/141 (27%), Positives = 64/141 (44%), Gaps = 6/141 (4%)
Query: 89 VLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTL 147
VL + D GN G + R A G V+L D + +L VR+S+G ++ LP +V
Sbjct: 123 VLAHVRDPGNAGTVLRCADAAGAEAVVLTDASVDLYNPKAVRASVGSLFHLPVAVGVPVE 182
Query: 148 DLINELKTSGFLCLGASMQGSSQIEN-----LSLKKCALFLGSEHEGLSKKILAKMDTIL 202
+ L+ +G L A G ++ A G+E GL ++ A D +L
Sbjct: 183 RAVAGLREAGVRVLAADGAGEDDLDTELDAGTMGGPTAWVFGNEAWGLPEETRALTDAVL 242
Query: 203 SVKMRRDFDSLNVSVAAGILM 223
V + +SLN++ AA + +
Sbjct: 243 RVPIHGKAESLNLATAAAVCL 263
>gb|AAL32808.1| (AY062730) Unknown protein [Arabidopsis thaliana]
gb|AAM19346.1|AF499436_1 (AF499436) hypothetical protein [Arabidopsis thaliana]
Length = 589
Score = 48.9 bits (115), Expect = 4e-05
Identities = 62/265 (23%), Positives = 103/265 (38%), Gaps = 45/265 (16%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLS----------KEIDKKLFFALKKACP----NIIKV 49
V+YG ++ L+ + + +Y+ K+ DKK F + K NI +
Sbjct: 315 VVYGVSPVLAALSVGRREFYALYVQEGLDLSSNNRKKKDKKGFERVLKISEKLGLNIKET 374
Query: 50 DNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV-------KKAQKLLVLCGITDVGNIGGI 102
+A HQG++ V +KE+ +K + L +TD N+G I
Sbjct: 375 SKHDLNMVADNRPHQGLVLDASPLELVKVKELDPISSEEEKYSLWVALDEVTDPQNLGAI 434
Query: 103 FRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
RSAY G GV++ +V ++S G + + N + + +G+ +
Sbjct: 435 IRSAYFFGATGVVVCAKNSAPLSAVVSKASAGSLEVMELRYCKNMMQFLEASAENGWRVV 494
Query: 162 GASMQGSSQIEN--LSLKKCALFLGSEHEGLSK----------KILAKMDTILSVKMRRD 209
G S+ + N L L LG+E GL +I M ++V D
Sbjct: 495 GGSVSPKAVALNEVLPGSPTILVLGNEGTGLRPLVERSCTDLVRISGNMPNEVAVTESDD 554
Query: 210 -----------FDSLNVSVAAGILM 223
+SLNVSVAAG+ +
Sbjct: 555 AEGEGFRSFLAVESLNVSVAAGLFL 579
>ref|NP_179577.1| (NM_127545) hypothetical protein [Arabidopsis thaliana]
gb|AAC62129.1| (AC005169) hypothetical protein [Arabidopsis thaliana]
Length = 577
Score = 48.9 bits (115), Expect = 4e-05
Identities = 62/265 (23%), Positives = 103/265 (38%), Gaps = 45/265 (16%)
Query: 4 VIYGKQVIMHLLNSHQEKLQEIYLS----------KEIDKKLFFALKKACP----NIIKV 49
V+YG ++ L+ + + +Y+ K+ DKK F + K NI +
Sbjct: 303 VVYGVSPVLAALSVGRREFYALYVQEGLDLSSNNRKKKDKKGFERVLKISEKLGLNIKET 362
Query: 50 DNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV-------KKAQKLLVLCGITDVGNIGGI 102
+A HQG++ V +KE+ +K + L +TD N+G I
Sbjct: 363 SKHDLNMVADNRPHQGLVLDASPLELVKVKELDPISSEEEKYSLWVALDEVTDPQNLGAI 422
Query: 103 FRSAYCLGMGGVILDFAKELAYEGIV-RSSLGLMYDLPFSVMPNTLDLINELKTSGFLCL 161
RSAY G GV++ +V ++S G + + N + + +G+ +
Sbjct: 423 IRSAYFFGATGVVVCAKNSAPLSAVVSKASAGSLEVMELRYCKNMMQFLEASAENGWRVV 482
Query: 162 GASMQGSSQIEN--LSLKKCALFLGSEHEGLSK----------KILAKMDTILSVKMRRD 209
G S+ + N L L LG+E GL +I M ++V D
Sbjct: 483 GGSVSPKAVALNEVLPGSPTILVLGNEGTGLRPLVERSCTDLVRISGNMPNEVAVTESDD 542
Query: 210 -----------FDSLNVSVAAGILM 223
+SLNVSVAAG+ +
Sbjct: 543 AEGEGFRSFLAVESLNVSVAAGLFL 567
>ref|NP_218494.1| (NC_000919) conserved hypothetical protein [Treponema pallidum]
pir||H71372 conserved hypothetical protein TP0054 - syphilis spirochete
gb|AAC65050.1| (AE001190) conserved hypothetical protein [Treponema pallidum]
Length = 319
Score = 48.1 bits (113), Expect = 7e-05
Identities = 51/240 (21%), Positives = 103/240 (42%), Gaps = 21/240 (8%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKL-----FFALKKACPNIIKVDNKKAQSLAK 59
+ G + + L + H EK+ + + K+ + A +K + ++ + L +
Sbjct: 28 VCGLRAVETLGSIHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYR--SANTQELERLTQ 85
Query: 60 GGNHQGVLAKVELPLAVSLKE------VKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGG 113
+HQGV A ++ P ++ V++ + +++L + D N+G I RSA G+
Sbjct: 86 SVHHQGVAATIDEPRFPAVTHSQVEFWVQRREFVVLLDRVGDAHNLGAIIRSAAFFGVHS 145
Query: 114 VILDFAKELAY--EGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQI 171
+++ ++ A R + G M + N +++ E+ +GAS +
Sbjct: 146 LVVSDCRQQAQVTSATYRVAQGGMEFVQLLRCTNAQEVL-EMCAGKMTRVGASPHAFRSL 204
Query: 172 ENLSL-----KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILMDKI 226
LS + L LG+E GLS+ + A D + + +SLNV+ A + + I
Sbjct: 205 TRLSNILSPEEAVILVLGNEETGLSEHLTAHCDHLCRIAGSGQVESLNVAQAGALFLSTI 264
>ref|NP_662143.1| (NC_002932) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
gb|AAM72485.1| (AE012885) SpoU rRNA methylase family protein [Chlorobium tepidum
TLS]
Length = 169
Score = 47.8 bits (112), Expect = 9e-05
Identities = 35/140 (25%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
Query: 88 LVLCGITDVGNIGGIFRSAYCLGMGGVILD-FAKELAYEGIVRSSLGLMYDLPFSVMPNT 146
L+L I + N+G +FR+A G+ +++ + + I +++LG +P+ +
Sbjct: 19 LMLYNIRSMWNVGAMFRTADAAGIDEIVITGYTATPPRKEIDKTALGAQETVPWRHFADP 78
Query: 147 LDLINELKTSGFLCLGASM-QGSSQIENLSLKK--CALFLGSEHEGLSKKILAKMDTILS 203
++ I LK G + + S +L+ AL +G+E EG+ +L+ D ++
Sbjct: 79 VEAITVLKRESKKIFGLEIAENSRSYSSLTAGDFPLALIVGNEVEGIGDALLSHCDGVIE 138
Query: 204 VKMRRDFDSLNVSVAAGILM 223
+ SLNV+VAAG+ +
Sbjct: 139 IPQYGVKHSLNVAVAAGVAL 158
>ref|NP_224726.1| (NC_000922) rRNA Methylase [Chlamydophila pneumoniae CWL029]
ref|NP_300585.1| (NC_002491) rRNA methylase [Chlamydophila pneumoniae J138]
ref|NP_444773.1| (NC_002179) spoU rRNA methylase family protein [Chlamydophila
pneumoniae AR39]
pir||C72066 rRNA methylase - Chlamydophila pneumoniae (strain CWL029)
gb|AAD18670.1| (AE001638) rRNA Methylase [Chlamydophila pneumoniae CWL029]
gb|AAF73643.1| (AE002183) spoU rRNA methylase family protein [Chlamydophila
pneumoniae AR39]
dbj|BAA98736.1| (AP002547) rRNA methylase [Chlamydophila pneumoniae J138]
Length = 265
Score = 47.8 bits (112), Expect = 9e-05
Identities = 55/199 (27%), Positives = 98/199 (48%), Gaps = 11/199 (5%)
Query: 30 EIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVS---LKEVKKAQK 86
E +K+ + LK+ I+ + L+ +H +A ++ + L + K AQ
Sbjct: 57 EKEKEFLYELKRNSTKILYCLDSTLAQLSFKEHHDSFVAVIQKRVWNKEDFLIQRKNAQP 116
Query: 87 L-LVLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMP 144
L++ + GN+G I R A G+ GVIL + +L +VRSSLG ++ LP ++
Sbjct: 117 FYLIIEQVEKPGNVGAILRIADGAGVDGVILCNPIVDLYNPNVVRSSLGAVFSLP--ILS 174
Query: 145 NTLDLINEL-KTSGFLCLGASMQGSSQIENLS-LKKCALFLGSEHEGLSKKILAKMDTIL 202
+ + EL K G+ S + + + + L AL GSE +GL++ ++ + +
Sbjct: 175 ISREEGKELFKQEGWTVFVTSPRAETMYFSKNYLGPTALVFGSEKDGLTEDWFSEDFSEI 234
Query: 203 SVKMRRDFDSLNV--SVAA 219
++ M + DSLN+ SVAA
Sbjct: 235 ALPMLGESDSLNLATSVAA 253
>ref|NP_005637.2| (NM_005646) TAR RNA binding protein 1; TAR RNA loop binding protein
[Homo sapiens]
Length = 1621
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/147 (22%), Positives = 68/147 (45%), Gaps = 5/147 (3%)
Query: 82 KKAQKLLVLCGITDVG-NIGGIFRSAYCLGMGGVILDFAKELAYEGIVRSSLGLMYDLPF 140
K +L+V+ + D N+GG+ R+ G +++ + ++ + S+ LP
Sbjct: 1459 KSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPL 1518
Query: 141 SVM--PNTLDLINELKTSGFLCLGASMQGSSQ--IENLSLKKCALFLGSEHEGLSKKILA 196
+ P +D + + KT G+ +G S + +K L LG+E EG+ ++
Sbjct: 1519 VEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQ 1578
Query: 197 KMDTILSVKMRRDFDSLNVSVAAGILM 223
++D + + + SLNV V+ +L+
Sbjct: 1579 QLDVCVEIPQQGIIRSLNVHVSGALLI 1605
>ref|XP_002084.6| (XM_002084) TAR RNA binding protein 1 [Homo sapiens]
pir||S62356 TRP-185 protein - human
gb|AAC50379.1| (U38847) TAR RNA loop binding protein [Homo sapiens]
prf||2203267A TRP-185 protein [Homo sapiens]
Length = 1621
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/147 (22%), Positives = 68/147 (45%), Gaps = 5/147 (3%)
Query: 82 KKAQKLLVLCGITDVG-NIGGIFRSAYCLGMGGVILDFAKELAYEGIVRSSLGLMYDLPF 140
K +L+V+ + D N+GG+ R+ G +++ + ++ + S+ LP
Sbjct: 1459 KSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPL 1518
Query: 141 SVM--PNTLDLINELKTSGFLCLGASMQGSSQ--IENLSLKKCALFLGSEHEGLSKKILA 196
+ P +D + + KT G+ +G S + +K L LG+E EG+ ++
Sbjct: 1519 VEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQ 1578
Query: 197 KMDTILSVKMRRDFDSLNVSVAAGILM 223
++D + + + SLNV V+ +L+
Sbjct: 1579 QLDVCVEIPQQGIIRSLNVHVSGALLI 1605
>ref|NP_224856.1| (NC_000922) rRNA Methylase [Chlamydophila pneumoniae CWL029]
ref|NP_300716.1| (NC_002491) rRNA methylase [Chlamydophila pneumoniae J138]
ref|NP_444639.1| (NC_002179) spoU rRNA methylase family protein [Chlamydophila
pneumoniae AR39]
pir||E72052 rRNA methylase - Chlamydophila pneumoniae (strain CWL029)
gb|AAD18799.1| (AE001648) rRNA Methylase [Chlamydophila pneumoniae CWL029]
gb|AAF73627.1| (AE002172) spoU rRNA methylase family protein [Chlamydophila
pneumoniae AR39]
dbj|BAA98867.1| (AP002547) rRNA methylase [Chlamydophila pneumoniae J138]
Length = 156
Score = 45.8 bits (107), Expect = 4e-04
Identities = 35/132 (26%), Positives = 67/132 (50%), Gaps = 5/132 (3%)
Query: 98 NIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTS 156
N G I R+ LG +++ LA + + R+ + L +V+ + + ++++
Sbjct: 13 NTGNIGRTCVALGAELILVRPLGFSLADKFVKRAGMDYWDKLQLTVVDSIEEALHDVPED 72
Query: 157 GFLCLGASMQGSSQIENLSLKKCALFL-GSEHEGLSKKILAKM-DTILSVKMRRDFDSLN 214
CL S +GS+ SL ++ GSE +GL K+IL K L + M++D SLN
Sbjct: 73 QIFCL--STKGSASYTEFSLPSSGTYVFGSESKGLPKEILKKYYKNCLRIPMQQDIRSLN 130
Query: 215 VSVAAGILMDKI 226
++ + GI++ ++
Sbjct: 131 LATSVGIVLYEV 142
>ref|NP_212186.1| (NC_001318) spoU protein (spoU) [Borrelia burgdorferi]
sp|O51081|Y052_BORBU Hypothetical tRNA/rRNA methyltransferase BB0052
pir||D70106 spoU protein (spoU) homolog - Lyme disease spirochete
gb|AAC66431.1| (AE001118) spoU protein (spoU) [Borrelia burgdorferi]
Length = 218
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 150 INELKTSGFLCLGASMQGSS-QIENLSLK-KCALFLGSEHEGLSKKILAKMDTILSVKMR 207
I+ LK+ G+ + S+ S +ENL++ K A+F G+E GLS ++L D + + M
Sbjct: 98 IDRLKSDGYSIVATSLNPKSINLENLTINNKMAIFFGTELTGLSAEVLGAADLYVKIPMY 157
Query: 208 RDFDSLNVSVAAGILM 223
S N+SVA I+M
Sbjct: 158 GFTQSYNISVAVAIVM 173
>dbj|BAA16467.1| (D90886) similar to [SwissProt Accession Number P33635]~start codon
is not identified yet [Escherichia coli]
Length = 445
Score = 45.1 bits (105), Expect = 6e-04
Identities = 47/221 (21%), Positives = 94/221 (42%), Gaps = 8/221 (3%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKKLFFALKKACPN---IIKVDNKKAQSLAKGG 61
+YG+ L S E + + + + + AL+ N VD + +
Sbjct: 138 VYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTE 197
Query: 62 NHQGVLAKVELPLAVSLKE-VKKAQK---LLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
+H GV ++ ++++ V +A +L L ++ N+GG+ RS G+ GV++
Sbjct: 198 HHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQ 257
Query: 118 FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSL- 176
A L +R++ G + N ++++++ + +G+ + S + + SL
Sbjct: 258 DAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLP 317
Query: 177 KKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSV 217
K L LG E+EGL D + + + LN+SV
Sbjct: 318 AKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISV 358
>ref|NP_297057.1| (NC_002620) spoU rRNA methylase family protein [Chlamydia
muridarum]
gb|AAF73591.1| (AE002337) spoU rRNA methylase family protein [Chlamydia muridarum]
Length = 265
Score = 44.3 bits (103), Expect = 0.001
Identities = 53/198 (26%), Positives = 90/198 (44%), Gaps = 22/198 (11%)
Query: 22 LQEIYLSKEIDKKLFFALKKACPNIIKVDNKKAQSLAKGGNHQGVLAKVELPLAVSLKEV 81
++++ KEI ++L F K+ N I V KK S + Q K + P + +++
Sbjct: 71 IEKLPCPKEILERLSF--KEHPDNFIAVFEKKRLSCQEFLRLQ---RKNQQPFYLIVEQA 125
Query: 82 KKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVIL-DFAKELAYEGIVRSSLGLMYDLPF 140
+K GNIG + R A G+ GVIL D +L ++RSSLG ++ +P
Sbjct: 126 EKP------------GNIGALLRIADGAGVDGVILCDPVVDLYNPNVIRSSLGAVFTVPI 173
Query: 141 --SVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKKCALFLGSEHEGLSKKILAKM 198
+ + L L+ E + F ++ + + + A+ GSE +GLS L
Sbjct: 174 WQASLEEVLALVREQEWKIFTTTPSTQ--TFYFDQNFCQPLAVVFGSEKDGLSPSWLDGS 231
Query: 199 DTILSVKMRRDFDSLNVS 216
+++ M DSLN+S
Sbjct: 232 FCNIALPMLGKADSLNLS 249
>ref|NP_246796.1| (NC_002663) unknown [Pasteurella multocida]
gb|AAK03941.1| (AE006223) unknown [Pasteurella multocida]
Length = 359
Score = 43.1 bits (100), Expect = 0.002
Identities = 49/229 (21%), Positives = 100/229 (43%), Gaps = 11/229 (4%)
Query: 5 IYGKQVIMHLLNSHQEKLQEIYLSKEIDKK---LFFALKKACPNIIKVDNKKAQSLAKGG 61
+YG+ L E + I+ + E+ KK LF L + VD+ + ++
Sbjct: 126 VYGENACQALFAQRPESIVRIWATVEMAKKSGELFSYLAEQKKAYHVVDSAELALVSGTA 185
Query: 62 NHQGVLAKVE----LPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILD 117
+H G+ V+ LA L +K L+++ G+ + N+GG+ R+ G+ GV+++
Sbjct: 186 HHGGICMLVKKARPFTLAGYLDIPRKQDCLVLIDGVQNPHNLGGVVRTCAVFGVKGVVIE 245
Query: 118 --FAKELAYEGIVRSSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQ-IENL 174
A L +R + G M + + + +L+ +G+ + + ++ + L
Sbjct: 246 QALADNLNAPAAMRVAEGGMEYVRVLETTDVPKALAQLRQAGYQLIHVTANKQAKPLSKL 305
Query: 175 SLKKCALFLGSEHEGLSKKILAKMDTILSVKMRRDFDSLNVSVAAGILM 223
+ +F+ +E S +LS+ + LN++VA GIL+
Sbjct: 306 HFTEKVVFVLNEQGDASLAQAEDEQVVLSLGNPLKAE-LNIAVATGILL 353
>ref|NP_014844.1| (NC_001147) Ribose methyltransferase for mitochondrial 21S rRNA;
Pet56p [Saccharomyces cerevisiae]
sp|P25270|PT56_YEAST RIBOSE METHYLTRANSFERASE PET56 (MITOCHONDRIAL LARGE RIBOSOMAL RNA
RIBOSE METHYLASE) (21S RRNA [GM2251]
2'O-METHYLTRANSFERASE)
pir||S48881 rRNA (guanosine-2'-O-)-methyltransferase (EC 2.1.1.-) - yeast
(Saccharomyces cerevisiae)
gb|AAA74564.1| (L19947) ribosomal RNA methylase [Saccharomyces cerevisiae]
emb|CAA99414.1| (Z75107) ORF YOR201c [Saccharomyces cerevisiae]
Length = 412
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/182 (25%), Positives = 73/182 (39%), Gaps = 27/182 (14%)
Query: 71 ELPLAVSLKEVKKAQKLLVLCGITDVGNIGGIFRSAYCLGMGGVILDFAKELAYEGIV-R 129
ELP + KK L L ITD NIG I RSAY LG+ +++ +V +
Sbjct: 228 ELPYGTKT-DAKKFPLGLYLDEITDPHNIGAIIRSAYFLGVDFIVMSRRNCSPLTPVVSK 286
Query: 130 SSLGLMYDLPFSVMPNTLDLINELKTSGFLCLGASMQGSSQIENLSLKK----------- 178
+S G + LP + L+ + + G S ++ E ++ K
Sbjct: 287 TSSGALELLPIFYVDKPLEFFTKSQEMGGWTFITSHLANATSEKYTVGKTISMHDLNGLC 346
Query: 179 ----CALFLGSEHEGLSKKILAKMDTILSVKM----------RRDFDSLNVSVAAGILMD 224
L +G+E +G+ + + D + + DSLNVSVA +L+D
Sbjct: 347 NELPVVLVVGNESQGVRTNLKMRSDFFVEIPFGGIEKGNRAPEPIVDSLNVSVATALLID 406
Query: 225 KI 226
I
Sbjct: 407 NI 408
>ref|NP_495375.1| (NM_062974) rRNA methylase [Caenorhabditis elegans]
pir||T28895 hypothetical protein T14B4.1 - Caenorhabditis elegans
gb|AAK31550.1| (U50191) Hypothetical protein T14B4.1 [Caenorhabditis elegans]
Length = 1203
Score = 41.6 bits (96), Expect = 0.007
Identities = 34/145 (23%), Positives = 68/145 (46%), Gaps = 7/145 (4%)
Query: 87 LLVLCGITDV-GNIGGIFRSAYCLGMGGVILD---FAKELAYEGIVRSSLGLMYDLPFSV 142
L+V+ + D N+GGI R++ G+ +++ A++ ++ + SS +
Sbjct: 1050 LIVVASLVDKPNNLGGICRTSEIFGVDTLVVADVLVAQDANFKALSMSSENWQ-KIEGVK 1108
Query: 143 MPNTLDLINELKTSGFLCLGASMQGSSQIEN--LSLKKCALFLGSEHEGLSKKILAKMDT 200
N L + L+ +G+ + A S + + + KK + +G E EG+ +L +D
Sbjct: 1109 RTNLLPYLQNLRANGYTVIAAEQTTDSVMMHDFVFPKKAVIVMGDEKEGVPVNLLRAVDQ 1168
Query: 201 ILSVKMRRDFDSLNVSVAAGILMDK 225
+ +K SLNV V A +++ K
Sbjct: 1169 TVEIKQVGHTRSLNVHVTAALMIAK 1193
Database: /home/scwang/download_20020708_db/nr
Posted date: Aug 7, 2002 12:55 PM
Number of letters in database: 324,149,939
Number of sequences in database: 1,026,957
Lambda K H
0.320 0.138 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,051,280
Number of Sequences: 1026957
Number of extensions: 4576761
Number of successful extensions: 11413
Number of sequences better than 1.0e-02: 139
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 11202
Number of HSP's gapped (non-prelim): 139
length of query: 227
length of database: 324,149,939
effective HSP length: 117
effective length of query: 110
effective length of database: 203,995,970
effective search space: 22439556700
effective search space used: 22439556700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 95 (41.2 bits)