BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15645366|ref|NP_207540.1| conserved hypothetical
protein [Helicobacter pylori 26695]
         (393 letters)

Database: /home/scwang/download_20020708_db/nr
           1,026,957 sequences; 324,149,939 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_207540.1|  (NC_000915) conserved hypothetical protein...   795  0.0
ref|NP_223402.1|  (NC_000921) putative [Helicobacter pylori ...   727  0.0
ref|NP_282425.1|  (NC_002163) ypothetical protein Cj1278c [C...   211  2e-53
ref|NP_228733.1|  (NC_000853) conserved hypothetical protein...    98  2e-19
ref|NP_438504.1|  (NC_000907) conserved hypothetical protein...    92  8e-18
ref|NP_660863.1|  (NC_004061) hypothetical 27.3 kD protein i...    92  1e-17
ref|NP_246255.1|  (NC_002663) unknown [Pasteurella multocida...    91  2e-17
ref|NP_240357.1|  (NC_002528) hypothetical protein [Buchnera...    91  2e-17
ref|NP_457502.1|  (NC_003198) conserved hypothetical protein...    88  2e-16
ref|NP_404567.1|  (NC_003143) Putative methyltransferase [Ye...    87  3e-16
ref|NP_418869.1|  (NC_002696) conserved hypothetical protein...    87  4e-16
ref|NP_462025.1|  (NC_003197) putative S-adenosylmethionine-...    85  1e-15
ref|NP_213039.1|  (NC_000918) hypothetical protein [Aquifex ...    84  2e-15
ref|NP_284257.1|  (NC_003116) conserved hypothetical protein...    83  6e-15
ref|NP_221195.1|  (NC_000963) POSSIBLE PROTOPORPHYRINOGEN OX...    82  1e-14
ref|NP_274347.1|  (NC_003112) conserved hypothetical protein...    82  1e-14
ref|NP_602422.1|  (NC_003454) 3-deoxy-D-manno-octulosonic-ac...    82  1e-14
pir||A38535  hypothetical protein (MicA region) - Escherichi...    81  2e-14
gb|AAA72956.1|  (M59471) [micA] gene products [Escherichia c...    81  2e-14
ref|NP_417435.1|  (NC_000913) orf, hypothetical protein [Esc...    81  2e-14
ref|NP_289532.1|  (NC_002655) orf, hypothetical protein [Esc...    80  4e-14
ref|NP_360951.1|  (NC_003103) possible protoporphyrinogen ox...    79  7e-14
ref|NP_230107.1|  (NC_002505) conserved hypothetical protein...    79  9e-14
ref|NP_325997.1|  (NC_002771) conserved hypothetical protein...    78  2e-13
ref|NP_249073.1|  (NC_002516) DNA mismatch repair protein Mi...    77  5e-13
sp|Q9I6B3|MT04_PSEAE  Hypothetical methyltransferase PA0382        77  5e-13
ref|NP_384518.1|  (NC_003047) CONSERVED HYPOTHETICAL PROTEIN...    76  8e-13
sp|Q9F411|MT04_MYCHO  Hypothetical methyltransferase MG347 h...    75  2e-12
ref|NP_244127.1|  (NC_002570) BH3261~unknown conserved prote...    74  2e-12
ref|NP_390868.1|  (NC_000964) similar to hypothetical protei...    74  4e-12
ref|NP_073017.1|  (NC_000908) conserved hypothetical protein...    74  4e-12
ref|NP_518824.1|  (NC_003295) CONSERVED HYPOTHETICAL PROTEIN...    72  1e-11
ref|NP_110210.1|  (NC_000912) similar to methyltransferase [...    72  1e-11
ref|NP_470992.1|  (NC_003212) similar to unknown proteins [L...    72  1e-11
ref|NP_658728.1|  (NC_003995) Methyltransf_4, Putative methy...    71  2e-11
ref|NP_465140.1|  (NC_003210) similar to unknown proteins [L...    71  2e-11
ref|NP_345067.1|  (NC_003028) conserved hypothetical protein...    70  4e-11
ref|NP_628290.1|  (NC_003888) conserved hypothetical protein...    70  4e-11
ref|NP_353395.1|  (NC_003062) AGR_C_634p [Agrobacterium tume...    69  7e-11
ref|NP_607764.1|  (NC_003485) putative methyltransferase [St...    69  7e-11
ref|NP_269750.1|  (NC_002737) conserved hypothetical protein...    69  7e-11
ref|NP_266905.1|  (NC_002662) HYPOTHETICAL PROTEIN [Lactococ...    69  9e-11
ref|NP_218905.1|  (NC_000919) conserved hypothetical protein...    69  9e-11
ref|NP_638497.1|  (NC_003902) DNA mismatch repair protein [X...    68  2e-10
ref|NP_349234.1|  (NC_003030) Predicted S-adenosylmethionine...    66  8e-10
ref|NP_643610.1|  (NC_003919) DNA mismatch repair protein [X...    65  1e-09
ref|NP_078103.1|  (NC_002162) conserved hypothetical [Ureapl...    65  1e-09
ref|NP_295403.1|  (NC_001263) conserved hypothetical protein...    64  2e-09
ref|NP_106193.1|  (NC_002678) hypothetical protein [Mesorhiz...    63  5e-09
ref|NP_602057.1|  (NC_003450) COG0220:Predicted S-adenosylme...    63  7e-09
ref|NP_298074.1|  (NC_002488) conserved hypothetical protein...    62  9e-09
ref|NP_540886.1|  (NC_003317) SAM-DEPENDENT METHYLTRANSFERAS...    61  3e-08
sp|P73161|MT04_SYNY3  Hypothetical methyltransferase sll1300       60  3e-08
ref|NP_646508.1|  (NC_003923) conserved hypothetical protein...    60  3e-08
ref|NP_440507.1|  (NC_000911) hypothetical protein [Synechoc...    60  3e-08
sp|Q9KWZ4|MT04_STAAU  Hypothetical methyltransferase >gi|732...    60  4e-08
ref|NP_372272.1|  (NC_002758) conserved hypothetical protein...    60  4e-08
ref|NP_296595.1|  (NC_002620) conserved hypothetical protein...    56  8e-07
ref|NP_485885.1|  (NC_003272) hypothetical protein [Nostoc s...    55  1e-06
dbj|BAB09565.1|  (AB006706) gb|AAB08476.1~gene_id:MVA3.1~sim...    55  2e-06
ref|NP_568355.1|  (NM_121772) putative protein [Arabidopsis ...    55  2e-06
ref|NP_214722.1|  (NC_000962) hypothetical protein Rv0208c [...    54  2e-06
ref|NP_220350.1|  (NC_000117) rRNA Methylase (possible) [Chl...    54  3e-06
sp|O84836|MT04_CHLTR  Hypothetical methyltransferase CT829         54  3e-06
sp|P72546|MT04_SYNP7  Hypothetical methyltransferase DC13 >g...    54  3e-06
ref|NP_225180.1|  (NC_000922) predicted rRNA Methylase [Chla...    54  3e-06
ref|NP_561340.1|  (NC_003366) conserved hypothetical protein...    53  7e-06
ref|NP_302680.1|  (NC_002677) conserved hypothetical protein...    51  2e-05
emb|CAB08804.1|  (Z95398) unknown [Mycobacterium leprae]           51  2e-05
ref|NP_586458.1|  (NC_003237) similarity to HYPOTHETICAL MET...    50  3e-05
ref|NP_633973.1|  (NC_003901) methyltransferase [Methanosarc...    48  2e-04
ref|NP_521916.1|  (NC_003296) HYPOTHETICAL PROTEIN [Ralstoni...    45  0.001
gb|EAA13331.1|  (AAAB01008968) ebiP3460 [Anopheles gambiae s...    45  0.001
>ref|NP_207540.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
           26695]
 sp|O25443|MT04_HELPY Hypothetical methyltransferase HP0747
 pir||C64613 conserved hypothetical protein HP0747 - Helicobacter pylori
           (strain 26695)
 gb|AAD07796.1| (AE000587) conserved hypothetical protein [Helicobacter pylori
           26695]
          Length = 393

 Score =  795 bits (2053), Expect = 0.0
 Identities = 393/393 (100%), Positives = 393/393 (100%)

Query: 1   MPHFLAKLDFKPLEYPLIEGDFCFHREFLSLKNPTKSCVYASFKDRIFLLQKIRRANDFL 60
           MPHFLAKLDFKPLEYPLIEGDFCFHREFLSLKNPTKSCVYASFKDRIFLLQKIRRANDFL
Sbjct: 1   MPHFLAKLDFKPLEYPLIEGDFCFHREFLSLKNPTKSCVYASFKDRIFLLQKIRRANDFL 60

Query: 61  IKSEKATPLKREVLKQALRIYSQSFEVISHNLQENSKHASGKKTLDLGTFEDFIQKNQAP 120
           IKSEKATPLKREVLKQALRIYSQSFEVISHNLQENSKHASGKKTLDLGTFEDFIQKNQAP
Sbjct: 61  IKSEKATPLKREVLKQALRIYSQSFEVISHNLQENSKHASGKKTLDLGTFEDFIQKNQAP 120

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV
Sbjct: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFEDS 240
           LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFEDS
Sbjct: 181 LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFEDS 240

Query: 241 LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNHAFDFS 300
           LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNHAFDFS
Sbjct: 241 LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNHAFDFS 300

Query: 301 FDTITISKKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLTE 360
           FDTITISKKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLTE
Sbjct: 301 FDTITISKKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLTE 360

Query: 361 NQIFYLNKSPLKTLNNHKAHLLLQNILSQKGIG 393
           NQIFYLNKSPLKTLNNHKAHLLLQNILSQKGIG
Sbjct: 361 NQIFYLNKSPLKTLNNHKAHLLLQNILSQKGIG 393
>ref|NP_223402.1| (NC_000921) putative [Helicobacter pylori J99]
 sp|Q9ZL96|MT04_HELPJ Hypothetical methyltransferase JHP0684
 pir||D71900 hypothetical protein jhp0684 - Helicobacter pylori (strain J99)
 gb|AAD06272.1| (AE001500) putative [Helicobacter pylori J99]
          Length = 400

 Score =  727 bits (1876), Expect = 0.0
 Identities = 361/390 (92%), Positives = 371/390 (94%)

Query: 1   MPHFLAKLDFKPLEYPLIEGDFCFHREFLSLKNPTKSCVYASFKDRIFLLQKIRRANDFL 60
           MPHFLAKLD KPLEYPLI GDFCFHREFLSLK+PTKSCV+ASFK+ +FLLQKIRRA DFL
Sbjct: 1   MPHFLAKLDSKPLEYPLIRGDFCFHREFLSLKHPTKSCVHASFKNDVFLLQKIRRAGDFL 60

Query: 61  IKSEKATPLKREVLKQALRIYSQSFEVISHNLQENSKHASGKKTLDLGTFEDFIQKNQAP 120
           IKSEKATPLKRE+LKQALRIYSQSFEVISHNLQENSKHAS KK LDL TFEDFIQKNQAP
Sbjct: 61  IKSEKATPLKREILKQALRIYSQSFEVISHNLQENSKHASQKKALDLETFEDFIQKNQAP 120

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           ILIEIGFGSGRHLIELAKNNPT TCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV
Sbjct: 121 ILIEIGFGSGRHLIELAKNNPTTTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFEDS 240
           LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSL FEDS
Sbjct: 181 LESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLCFEDS 240

Query: 241 LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNHAFDFS 300
           LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL+IYSL  +E P  NHA DFS
Sbjct: 241 LKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLKIYSLGLDENPTQNHALDFS 300

Query: 301 FDTITISKKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLTE 360
           FDTITI K+SVG ILKT KII+EGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLL E
Sbjct: 301 FDTITIDKESVGAILKTPKIIKEGYFVHVCNIYENKGDFLVELSMGDFDWPVRLFVLLAE 360

Query: 361 NQIFYLNKSPLKTLNNHKAHLLLQNILSQK 390
           NQ+FYLNKSPLKTLNNHKAHLLLQNILSQK
Sbjct: 361 NQVFYLNKSPLKTLNNHKAHLLLQNILSQK 390
>ref|NP_282425.1| (NC_002163) ypothetical protein Cj1278c [Campylobacter jejuni]
 sp|Q9PN20|MT04_CAMJE Hypothetical methyltransferase CJ1278c
 pir||H81335 hypothetical protein Cj1278c [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73532.1| (AL139077) ypothetical protein Cj1278c [Campylobacter jejuni]
          Length = 392

 Score =  211 bits (536), Expect = 2e-53
 Identities = 134/394 (34%), Positives = 215/394 (54%), Gaps = 15/394 (3%)

Query: 1   MPHFLAKLDFKPLEYPLIEGDFCFHREFLSL-KNPTKSCVYASFKDRIFLLQKIRRANDF 59
           MP+F +K   K +  P  + D     EFL L KN   S +Y   ++  F LQ  +  N F
Sbjct: 1   MPNFKSK-KIKEINLPYSKDDV----EFLWLAKNDNVSLIYTKVQEESFFLQIKKAQNGF 55

Query: 60  LIKSEKAT-PLKREVLKQALRIYSQSF--EVISHNLQENSKHASGKKTLDLGTFEDFIQK 116
           +IK +K T P K   L++AL+I+ + F  ++I+      +     K    +  F++ + +
Sbjct: 56  VIKGDKHTKPSKIGYLQKALKIFKEGFCEDIINEAFGLKNNALIEKTPFIVDNFDELLSR 115

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
            Q  I IEIGFGSGRHL+  AK NP    LG+EI+ P++ Q  K  +  ++ N+ ++Q D
Sbjct: 116 LQGKIYIEIGFGSGRHLLYQAKENPNVLILGVEIYNPALTQVAKLAKAQNVNNILLIQSD 175

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
            RL+L  + +   EKIF+HFPVPW++K HRRV+ + F  E  RVL   G  ELRTD   Y
Sbjct: 176 ARLLLSVLKSKSVEKIFLHFPVPWDKKPHRRVIGKDFCKECARVLVQNGRFELRTDSFEY 235

Query: 237 FEDSLKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNHA 296
           F  +L+  L     +  ++KN  + + SKYE RW K +K+IYDL +++  +N+   +   
Sbjct: 236 FNFTLEQFLTFPAPKFSLRKNENLEISSKYEDRWKKQEKNIYDLWVWN--FNQECKNYEL 293

Query: 297 FDFSFDTITISKKSVGTI---LKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFDWPVR 353
            +F+  ++  SK+ +  I    K   I ++ +F+H  +IY+   + L++++ G F+ P  
Sbjct: 294 NEFNLSSVEFSKEDLKKIEQNFKNITIKKDDFFLHFESIYKQDENLLLKVAFGAFNKPEH 353

Query: 354 LFVLLTENQIFYLNKSPLKTLNNHKAHLLLQNIL 387
            ++ L +  I +  K P K   N KA   L+ IL
Sbjct: 354 CYLHL-DKTIDFAFKEPFKIQENIKAINELKEIL 386
>ref|NP_228733.1| (NC_000853) conserved hypothetical protein [Thermotoga maritima]
 sp|Q9X027|MT04_THEMA Hypothetical methyltransferase TM0925
 pir||F72317 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
 gb|AAD36006.1|AE001756_9 (AE001756) conserved hypothetical protein [Thermotoga maritima]
          Length = 313

 Score = 97.8 bits (242), Expect = 2e-19
 Identities = 54/165 (32%), Positives = 94/165 (56%), Gaps = 4/165 (2%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +A I++EIGFG+G  L ELA+ +P K  +G E+   S  +A K+ +  +LKN+ +++ D 
Sbjct: 27  KAKIVVEIGFGNGEFLAELARRHPEKDFVGFEVSITSFVKAQKKFKRYNLKNVRLVKVDA 86

Query: 178 RLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
           R  L E  P++  EK++++FP PW +K+H  RR+ S  FL     VL+  G +E  TD+ 
Sbjct: 87  RFGLRELFPDNSVEKVYINFPCPWPKKRHESRRITSYDFLQTLSAVLEMDGTVEFATDEE 146

Query: 235 LYFEDSLKLALKNFQCEIEI-KKNAQIPVVSKYEARWNKLKKDIY 278
            Y  + L     +    +++ ++N +  V ++YE +W    K  +
Sbjct: 147 WYAREVLDTFESSEYFVVDVFEENFKRDVETRYERKWKSQGKKTF 191
>ref|NP_438504.1| (NC_000907) conserved hypothetical protein [Haemophilus influenzae
           Rd]
 sp|P44648|MT04_HAEIN Probable methyltransferase HI0340
 pir||F64148 hypothetical protein HI0340 - Haemophilus influenzae (strain Rd
           KW20)
 gb|AAC22002.1| (U32719) conserved hypothetical protein [Haemophilus influenzae Rd]
          Length = 246

 Score = 92.4 bits (228), Expect = 8e-18
 Identities = 55/175 (31%), Positives = 91/175 (51%), Gaps = 8/175 (4%)

Query: 114 IQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHIL 173
           I  N  P+++EIGFG G+ L+++A  NP K  LGIE+HTP +   +       + NL ++
Sbjct: 67  IYGNDNPVVLEIGFGMGKSLVDMAFANPDKNYLGIEVHTPGVGACIAYAVEKGVTNLRVI 126

Query: 174 QGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELR 230
             D   +L +S+ +     + + FP PW++ KH  RR++   F+ + ++ L   GF+ + 
Sbjct: 127 CHDATEILRDSIADGALGGLQLFFPDPWHKAKHHKRRIVQPHFVTQVIQKLGENGFIHMA 186

Query: 231 TDDSLYFEDSLKLALKNFQCEIEIKKNAQIP-----VVSKYEARWNKLKKDIYDL 280
           TD   Y E  L++   N       K    IP      ++K+EAR  KL   ++DL
Sbjct: 187 TDWENYAEQMLEVLSANTDLVNTSKNGDYIPRPDFRPLTKFEARGYKLGHGVWDL 241
>ref|NP_660863.1| (NC_004061) hypothetical 27.3 kD protein in ansB-mutY [Buchnera
           aphidicola str. Sg (Schizaphis graminum)]
 gb|AAM68074.1| (AE014127) hypothetical 27.3 kD protein in ansB-mutY [Buchnera
           aphidicola str. Sg (Schizaphis graminum)]
          Length = 239

 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 58/163 (35%), Positives = 84/163 (50%), Gaps = 4/163 (2%)

Query: 116 KNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQG 175
           KN AP+++EIGFGSG  L++ A N P K  LGIE++   I   L+      + NL I+  
Sbjct: 61  KNSAPVILEIGFGSGESLVKTAANFPNKNFLGIEVYKSGIGSCLRLAHYSGINNLKIIYH 120

Query: 176 DGRLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTD 232
           D   V++ M  +H   K+ + FP PWN+K+H  RR++ + FL + L+ L   G L + TD
Sbjct: 121 DAIEVIDQMILDHTLSKVQIFFPDPWNKKRHHKRRMIQDFFLIKILKKLNNDGILHIVTD 180

Query: 233 DSLYFEDSLKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKK 275
              Y    L L ++N    I + K        KY    N  KK
Sbjct: 181 SKEYNFFILNL-IQNIDNYINLSKKRMCFEHFKYRLVTNFEKK 222
>ref|NP_246255.1| (NC_002663) unknown [Pasteurella multocida]
 sp|Q9CLC2|MT04_PASMU Hypothetical methyltransferase PM1317
 gb|AAK03401.1| (AE006170) unknown [Pasteurella multocida]
          Length = 255

 Score = 91.3 bits (225), Expect = 2e-17
 Identities = 53/175 (30%), Positives = 90/175 (51%), Gaps = 8/175 (4%)

Query: 114 IQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHIL 173
           I  N  P+++EIGFG G  L+++A  NP +  LGIE+HTP +   +       +KNL I+
Sbjct: 76  IYGNNNPVVLEIGFGMGHSLVDMALQNPERNYLGIEVHTPGVGACIAYAVEKGVKNLRII 135

Query: 174 QGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELR 230
             D   +L + + +H    + + FP PW++ KH  RR++  +F+N   + L   GF+ + 
Sbjct: 136 CHDATEILRDCIADHSLGGLQLFFPDPWHKAKHHKRRIVQPQFVNTITQKLTTGGFIHMA 195

Query: 231 TDDSLYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
           TD   Y E  L +      L+N     +         ++K+E R ++L   ++DL
Sbjct: 196 TDWENYAEHMLAVLQQAEGLQNTSATHDYIPRPDFRPLTKFEQRGHRLGHGVWDL 250
>ref|NP_240357.1| (NC_002528) hypothetical protein [Buchnera sp. APS]
 sp|P57616|MT04_BUCAI Hypothetical methyltransferase BU551
 dbj|BAB13243.1| (AP001119) hypothetical protein [Buchnera sp. APS]
          Length = 239

 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 61/176 (34%), Positives = 94/176 (52%), Gaps = 10/176 (5%)

Query: 114 IQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHIL 173
           I K++API++EIGFGSG  L++ A N P K  LGIE++   I   L       ++NL I+
Sbjct: 59  IFKHRAPIILEIGFGSGESLVKTAMNFPEKNFLGIEVYKSGIGSCLHYASSYQIQNLRII 118

Query: 174 QGDGRLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELR 230
             D   V+ +M P+    K+ + FP PW++K+H  RR+L   FL    + L   G L + 
Sbjct: 119 YYDATEVMYNMIPDDTLSKVQIFFPDPWHKKRHHKRRLLKNIFLKIITKKLIIDGILHIA 178

Query: 231 TDD---SLYFEDSLKLALKNFQCEIEIKKNAQIPV---VSKYEARWNKLKKDIYDL 280
           TD    + Y  D +K  +KN++   E     + PV   ++K+E +     K I+DL
Sbjct: 179 TDSESYAFYILDEIK-DIKNYKNLSEKNNFVKRPVSRIITKFEKKGLLQGKKIFDL 233
>ref|NP_457502.1| (NC_003198) conserved hypothetical protein [Salmonella enterica
           subsp. enterica serovar Typhi]
 emb|CAD02934.1| (AL627277) conserved hypothetical protein [Salmonella enterica
           subsp. enterica serovar Typhi]
          Length = 239

 Score = 88.2 bits (217), Expect = 2e-16
 Identities = 53/171 (30%), Positives = 86/171 (49%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK  P +  LGIE+H+P +   L       ++NLH++  D 
Sbjct: 63  EAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGACLASAHEEGVENLHVMCHDA 122

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F    L  LK  G   + TD  
Sbjct: 123 VEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVPFAELVLSKLKLGGVFHMATDWE 182

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++       KN     +     +   V+K+E R ++L   ++DL
Sbjct: 183 AYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTKFEQRGHRLGHGVWDL 233
>ref|NP_404567.1| (NC_003143) Putative methyltransferase [Yersinia pestis]
 emb|CAC89794.1| (AJ414145) Putative methyltransferase [Yersinia pestis]
          Length = 239

 Score = 87.0 bits (214), Expect = 3e-16
 Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +API++EIGFG G  L+ +A NNP +  LGIE+H+P +   L       L NL I+  D 
Sbjct: 63  EAPIVLEIGFGMGTSLVTMATNNPQQNFLGIEVHSPGVGACLSSAHDAGLSNLRIMCHDA 122

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VLE+M P    + + + FP PW++ +H  RR++   F+      LK  G   + TD  
Sbjct: 123 VEVLENMIPEASLDMVQLFFPDPWHKARHNKRRIVQTPFVELVKSKLKVGGVFHMATDWQ 182

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++        N   + +         ++K+E R  +L   ++DL
Sbjct: 183 PYAEHMLEVMSGVSGYLNLSEQNDYVPRPDSRPLTKFELRGQRLGHGVWDL 233
>ref|NP_418869.1| (NC_002696) conserved hypothetical protein [Caulobacter crescentus
           CB15]
 sp|P58088|MT04_CAUCR Hypothetical methyltransferase CC0049
 gb|AAK22037.1| (AE005679) conserved hypothetical protein [Caulobacter crescentus
           CB15]
          Length = 271

 Score = 86.7 bits (213), Expect = 4e-16
 Identities = 51/156 (32%), Positives = 86/156 (54%), Gaps = 7/156 (4%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           + +EIGFG G H+   A  NP    +G E     +A A++ +E   LKN+ I +GD R V
Sbjct: 101 VWLEIGFGGGEHMASQAGRNPETLVIGAEPFVNGVASAVRHVEEQALKNVRIHEGDARDV 160

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           ++ +P+   +++F+ FP PW++ +H  RR++  +F+ +  RV+KP   L   TD + Y E
Sbjct: 161 VDWLPDACLDRVFIMFPDPWHKARHNKRRLIQPEFVAKLARVMKPGAALRFATDWADYAE 220

Query: 239 DSLK--LALKNFQCEIEIKKNAQIP---VVSKYEAR 269
            + +  LA  +F+   E      IP   V ++YE +
Sbjct: 221 WTTERVLADPSFRFADEAADRNAIPADHVTTRYEEK 256
>ref|NP_462025.1| (NC_003197) putative S-adenosylmethionine-dependent
           methyltransferase [Salmonella typhimurium LT2]
 gb|AAL21984.1| (AE008842) putative S-adenosylmethionine-dependent
           methyltransferase [Salmonella typhimurium LT2]
          Length = 239

 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 52/171 (30%), Positives = 85/171 (49%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK  P +  LGIE+H+P +   L       ++NL ++  D 
Sbjct: 63  EAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGACLASANEEGVENLRVMCHDA 122

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F    L  LK  G   + TD  
Sbjct: 123 VEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVPFAELVLSKLKLGGVFHMATDWE 182

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++       KN     +     +   V+K+E R ++L   ++DL
Sbjct: 183 AYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTKFEQRGHRLGHGVWDL 233
>ref|NP_213039.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
 sp|O66479|MT04_AQUAE Hypothetical methyltransferase AQ_065
 pir||D70306 conserved hypothetical protein aq_065 - Aquifex aeolicus
 gb|AAC06452.1| (AE000672) hypothetical protein [Aquifex aeolicus]
          Length = 297

 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 77/284 (27%), Positives = 139/284 (48%), Gaps = 25/284 (8%)

Query: 123 IEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLVLE 182
           +EIGFG G  +++LAK NP K   GIEI   SI + +K++    LKN++    D      
Sbjct: 21  VEIGFGRGDFIVKLAKENPDKNFFGIEISQISIEKLMKRVGKKGLKNVYCTNVDAYWGFY 80

Query: 183 SM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFED 239
            +  ++  E I++++P PW +K+H  RR+   + L    + LK  G + +RTD+  + E 
Sbjct: 81  FLFRDNYVENIYMNYPDPWFKKRHHKRRLTKPERLYMFAKKLKLGGEIRIRTDNYEFLEF 140

Query: 240 SLKLA--LKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEWNETPFDNH-- 295
           + + A  L  F+ E E   N + P ++KYE +W  + K +Y L +  ++  E  F  H  
Sbjct: 141 TKESAKVLDCFEVE-EGTLNVKEP-LTKYEQKWLSMGKTLYKLILRKVK--EPKFVEHPE 196

Query: 296 ------AFDFSFDTITISKKSVGTILKTKKIIQEGYFVHVCNIYENKGDFLVELSMGDFD 349
                  F       ++  K + +  +  K+ +E YF     +++   DFLVE  + +  
Sbjct: 197 VEEVRELFPVKVKVESVDPKKIES--REIKLDEEVYF-KTFKVWQRDKDFLVECLLSEKG 253

Query: 350 WPVRLFVLLTENQIFY-LNKSP----LKTLNNHKAHLLLQNILS 388
           +  + F+ +   +  Y ++ SP    L+T N  ++   +  +LS
Sbjct: 254 YLQKFFIQIKRKEDGYVIDVSPYSEVLRTRNLQRSIQTVAQLLS 297
>ref|NP_284257.1| (NC_003116) conserved hypothetical protein [Neisseria meningitidis
           Z2491]
 sp|Q9JU19|MT04_NEIMA Hypothetical methyltransferase NMA1542
 pir||A81846 conserved hypothetical protein NMA1542 [imported] - Neisseria
           meningitidis (group A strain Z2491)
 emb|CAB84769.1| (AL162756) conserved hypothetical protein [Neisseria meningitidis
           Z2491]
          Length = 238

 Score = 82.8 bits (203), Expect = 6e-15
 Identities = 52/167 (31%), Positives = 87/167 (51%), Gaps = 6/167 (3%)

Query: 120 PILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRL 179
           P ++EIGFG G    E+A+  P    L I++H P +   LK IE   L+N+ +++ D   
Sbjct: 66  PKILEIGFGMGTATAEIARRLPETDFLAIDVHGPGVGNLLKLIEENHLENIRVMRHDAVE 125

Query: 180 VLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
           V+E+M  +   + I + FP PW++K+H  RR++   F+ + L  LK  G++ L TD   Y
Sbjct: 126 VVENMLQDGSLDGIHIFFPDPWHKKRHHKRRLIQAPFIAKLLPKLKTGGYIHLATDWEEY 185

Query: 237 FEDSLKLALKNFQCEIEIKKNAQIP---VVSKYEARWNKLKKDIYDL 280
            +  L++       +      A  P     +K+EAR  +L   ++DL
Sbjct: 186 AQQMLEVLSSFDSLQNTAADYAPTPDYRPETKFEARGKRLGHGVWDL 232
>ref|NP_221195.1| (NC_000963) POSSIBLE PROTOPORPHYRINOGEN OXIDASE  (hemK) [Rickettsia
           prowazekii]
 sp|Q9ZCB3|HEMK_RICPR HemK protein homolog (M.RprHemKP)
 pir||G71646 probable protoporphyrinogen oxidase (hemK) RP847 - Rickettsia
           prowazekii
 emb|CAA15271.1| (AJ235273) POSSIBLE PROTOPORPHYRINOGEN OXIDASE  (hemK) [Rickettsia
           prowazekii]
          Length = 518

 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 44/134 (32%), Positives = 72/134 (52%), Gaps = 2/134 (1%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           + +EIGFG G HLI  AK NP    +G+E++   +A  LK     ++ N  +   +  L+
Sbjct: 344 VFLEIGFGMGEHLINQAKINPDTLFIGVEVYLNGVANVLKHSAQHNITNFLLFPNNLDLI 403

Query: 181 LESMPNHRCEKIFVHFPVPW--NEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           L  +PN+  + I++ FP PW  N+KK +R+ +++ L      LK  G L   +D   YF 
Sbjct: 404 LNDLPNNSLDGIYILFPDPWIKNKKKKKRIFNKERLKILQNKLKNNGNLVFASDIENYFY 463

Query: 239 DSLKLALKNFQCEI 252
           +++ L  +N   EI
Sbjct: 464 EAMALIRQNGNFEI 477
>ref|NP_274347.1| (NC_003112) conserved hypothetical protein [Neisseria meningitidis
           MC58]
 sp|Q9JZ24|MT04_NEIMB Hypothetical methyltransferase NMB1328
 pir||C81095 conserved hypothetical protein NMB1328 [imported] - Neisseria
           meningitidis (group B strain MD58)
 gb|AAF41703.1| (AE002481) conserved hypothetical protein [Neisseria meningitidis
           MC58]
          Length = 238

 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 51/167 (30%), Positives = 87/167 (51%), Gaps = 6/167 (3%)

Query: 120 PILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRL 179
           P ++EIGFG G    E+A+  P    L I++H P +   LK I+   L+N+ +++ D   
Sbjct: 66  PKILEIGFGMGTATAEIARRLPETDFLAIDVHGPGVGNLLKLIDENHLENIRVMRHDAVE 125

Query: 180 VLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
           V+E+M  +   + I + FP PW++K+H  RR++   F+ + L  LK  G++ L TD   Y
Sbjct: 126 VVENMLQDGSLDGIHIFFPDPWHKKRHHKRRLIQAPFIAKLLPKLKTGGYIHLATDWEEY 185

Query: 237 FEDSLKLALKNFQCEIEIKKNAQIP---VVSKYEARWNKLKKDIYDL 280
            +  L++       +      A  P     +K+EAR  +L   ++DL
Sbjct: 186 AQQMLEVLSSFDSLQNTAADYAPTPDYRPETKFEARGKRLGHGVWDL 232
>ref|NP_602422.1| (NC_003454) 3-deoxy-D-manno-octulosonic-acid transferase;
           SAM-dependent methyltransferase [Fusobacterium nucleatum
           subsp. nucleatum ATCC 25586]
 gb|AAL93721.1| (AE010468) 3-deoxy-D-manno-octulosonic-acid transferase;
           SAM-dependent methyltransferase [Fusobacterium nucleatum
           subsp. nucleatum ATCC 25586]
          Length = 640

 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 38/135 (28%), Positives = 75/135 (55%), Gaps = 2/135 (1%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N   I +EIG GSG  + +LA+ NP K  +G+E+    +  A ++ +  ++KN+  L+  
Sbjct: 463 NSDQIAVEIGTGSGNFIYQLAERNPNKNFIGLELRFKRLVLAAQKCKKRNIKNVAFLRKR 522

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
           G  + + + N+   +++++FP PW   +  R++ E+      +++K  G L  +TD  +Y
Sbjct: 523 GEELEDFLANNEISEMYINFPDPWEGTEKNRIIQERLFKTLDKIMKKDGMLYFKTDHDVY 582

Query: 237 FEDSLKL--ALKNFQ 249
           + D L+L   L N++
Sbjct: 583 YNDVLELVKTLDNYE 597
>pir||A38535 hypothetical protein (MicA region) - Escherichia coli
          Length = 229

 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 51/171 (29%), Positives = 83/171 (47%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK+ P +  LGIE+H+P +   L       L NL ++  D 
Sbjct: 53  EAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDA 112

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F       L+  G   + TD  
Sbjct: 113 VEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWE 172

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++       KN     +         V+K+E R ++L   ++DL
Sbjct: 173 PYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDL 223
>gb|AAA72956.1| (M59471) [micA] gene products [Escherichia coli]
          Length = 230

 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 51/171 (29%), Positives = 83/171 (47%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK+ P +  LGIE+H+P +   L       L NL ++  D 
Sbjct: 54  EAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDA 113

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F       L+  G   + TD  
Sbjct: 114 VEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWE 173

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++       KN     +         V+K+E R ++L   ++DL
Sbjct: 174 PYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDL 224
>ref|NP_417435.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
 sp|P32049|MT04_ECOLI Hypothetical methyltransferase yggH
 pir||G65081 hypothetical 27.3 kD protein in mutY 5' region - Escherichia coli
           (strain K-12)
 gb|AAA69127.1| (U28377) ORF_f239; alternate name yggH; orf of M59471 [Escherichia
           coli]
 gb|AAC75997.1| (AE000378) orf, hypothetical protein [Escherichia coli K12]
          Length = 239

 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 51/171 (29%), Positives = 83/171 (47%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK+ P +  LGIE+H+P +   L       L NL ++  D 
Sbjct: 63  EAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDA 122

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F       L+  G   + TD  
Sbjct: 123 VEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWE 182

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  L++       KN     +         V+K+E R ++L   ++DL
Sbjct: 183 PYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDL 233
>ref|NP_289532.1| (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7
           EDL933]
 ref|NP_311863.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
 gb|AAG58091.1|AE005526_4 (AE005526) orf, hypothetical protein [Escherichia coli O157:H7
           EDL933]
 dbj|BAB37259.1| (AP002563) hypothetical protein [Escherichia coli O157:H7]
          Length = 239

 Score = 80.1 bits (196), Expect = 4e-14
 Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 8/171 (4%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           +AP+ +EIGFG G  L+ +AK+ P +  LGIE+H+P +   L       L NL ++  D 
Sbjct: 63  EAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDA 122

Query: 178 RLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
             VL  M P++    + + FP PW++ +H  RR++   F       L+  G   + TD  
Sbjct: 123 VEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWE 182

Query: 235 LYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL 280
            Y E  +++       KN     +         V+K+E R ++L   ++DL
Sbjct: 183 PYAEHMIEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDL 233
>ref|NP_360951.1| (NC_003103) possible protoporphyrinogen oxidase [EC:1.3.3.4]
           [Rickettsia conorii]
 gb|AAL03852.1| (AE008678) possible protoporphyrinogen oxidase [EC:1.3.3.4]
           [Rickettsia conorii]
          Length = 524

 Score = 79.3 bits (194), Expect = 7e-14
 Identities = 48/156 (30%), Positives = 82/156 (51%), Gaps = 8/156 (5%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           + +EIGFG G H I  AK NP    +GIE++   +A  LK     ++ N  +   +  L+
Sbjct: 350 VFLEIGFGMGEHFINQAKMNPNALFIGIEVYLNGVANVLKLAGEQNITNFLLFPNNLDLI 409

Query: 181 LESMPNHRCEKIFVHFPVPW--NEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           L  +P++  + I++ FP PW  N++K +R+ +++ L      LK  G L   +D   YF 
Sbjct: 410 LNEIPSNSLDGIYILFPDPWIKNKQKKKRIFNKERLKLLQDKLKDNGNLVFASDIENYFY 469

Query: 239 DSLKLALKNFQCEIEIKKNAQIP-----VVSKYEAR 269
           ++++L  +N   EI I KN  +      V++KY  +
Sbjct: 470 EAIELIQQNGNFEI-INKNDYLKPHDNYVITKYHQK 504
>ref|NP_230107.1| (NC_002505) conserved hypothetical protein [Vibrio cholerae]
 sp|Q9KUR2|MT04_VIBCH Hypothetical methyltransferase VC0453
 pir||E82320 conserved hypothetical protein VC0453 [imported] - Vibrio cholerae
           (group O1 strain N16961)
 gb|AAF93626.1| (AE004132) conserved hypothetical protein [Vibrio cholerae]
          Length = 239

 Score = 79.0 bits (193), Expect = 9e-14
 Identities = 48/174 (27%), Positives = 87/174 (49%), Gaps = 9/174 (5%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  P+++EIGFG G  L+E+AKN P K  LGIE+H+P +   L       + NL ++  D
Sbjct: 61  NDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHD 120

Query: 177 GRLVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEA-LRVLKPRGFLELRTD 232
              V   M P++    + + FP PW++K+H  RR++  +F      +++   G   + TD
Sbjct: 121 AVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLMIGSGVFHMATD 180

Query: 233 DSLYFEDSLKL-----ALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLR 281
              Y E  +++        N   + +         ++K+E R ++L   ++D++
Sbjct: 181 WENYAEHMVEVMNQAPGFANLATDGDYVPRPDERPLTKFEQRGHRLGHGVWDIK 234
>ref|NP_325997.1| (NC_002771) conserved hypothetical protein [Mycoplasma pulmonis]
 emb|CAC13339.1| (AL445563) conserved hypothetical protein [Mycoplasma pulmonis]
          Length = 203

 Score = 78.2 bits (191), Expect = 2e-13
 Identities = 58/191 (30%), Positives = 99/191 (51%), Gaps = 9/191 (4%)

Query: 95  NSKHASGKKTLDLGTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPS 154
           N+K+A  +        ++F  K +    +EIG G G+ LIELA+ NP K  +GIE +   
Sbjct: 5   NNKNAKLELESCENVIKNFPFKVEKNSTLEIGMGKGQMLIELAQKNPQKIFVGIEKYPTV 64

Query: 155 IAQALKQIELLDLKNLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEK 212
              A K+ + L+L N  I+  D    L+       + I++ F  PW +K+H  RR+  EK
Sbjct: 65  ALIAAKKAKKLELNNFFIIVDDVENALDFFEG-TFDLIWLTFSDPWPKKRHYKRRLTYEK 123

Query: 213 FLNEALRVLKPRGFLELRTDDSLYFEDSLK------LALKNFQCEIEIKKNAQIPVVSKY 266
           FL    ++L   G ++L+TD+  +F+ +L+      L + N   ++E  + A+  V + Y
Sbjct: 124 FLKIYSKILSENGLIKLKTDNDDFFQWTLESLEKNGLNIINKTSDLEKSEFAKDNVKTSY 183

Query: 267 EARWNKLKKDI 277
           E ++  L K+I
Sbjct: 184 EQKFVSLGKNI 194
>ref|NP_249073.1| (NC_002516) DNA mismatch repair protein MicA [Pseudomonas
           aeruginosa]
 pir||E83596 DNA mismatch repair protein MicA PA0382 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
 gb|AAG03771.1|AE004476_1 (AE004476) DNA mismatch repair protein MicA [Pseudomonas
           aeruginosa]
          Length = 223

 Score = 76.6 bits (187), Expect = 5e-13
 Identities = 53/178 (29%), Positives = 86/178 (47%), Gaps = 8/178 (4%)

Query: 112 DFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLH 171
           D I   QAP   EIGFG G   +E+A   P    +G+E+H P +   L  +    L N+ 
Sbjct: 41  DAIFGRQAPRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVR 100

Query: 172 ILQGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLE 228
           +   D   VL   + +   +++ + FP PW++K+H  RR++  +F     R LK  G L 
Sbjct: 101 VYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHHKRRIVQPEFAELVRRKLKVGGVLH 160

Query: 229 LRTDDSLYFEDSLKL--ALKNFQCEIEIKKNAQIP---VVSKYEARWNKLKKDIYDLR 281
           + TD   Y E  L +  A   ++ + E  +    P    V+K+E R  +L   ++DL+
Sbjct: 161 MATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQERPVTKFERRGERLGHGVWDLK 218
>sp|Q9I6B3|MT04_PSEAE Hypothetical methyltransferase PA0382
          Length = 244

 Score = 76.6 bits (187), Expect = 5e-13
 Identities = 53/178 (29%), Positives = 86/178 (47%), Gaps = 8/178 (4%)

Query: 112 DFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLH 171
           D I   QAP   EIGFG G   +E+A   P    +G+E+H P +   L  +    L N+ 
Sbjct: 62  DAIFGRQAPRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVR 121

Query: 172 ILQGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLE 228
           +   D   VL   + +   +++ + FP PW++K+H  RR++  +F     R LK  G L 
Sbjct: 122 VYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHHKRRIVQPEFAELVRRKLKVGGVLH 181

Query: 229 LRTDDSLYFEDSLKL--ALKNFQCEIEIKKNAQIP---VVSKYEARWNKLKKDIYDLR 281
           + TD   Y E  L +  A   ++ + E  +    P    V+K+E R  +L   ++DL+
Sbjct: 182 MATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQERPVTKFERRGERLGHGVWDLK 239
>ref|NP_384518.1| (NC_003047) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
 emb|CAC41849.1| (AL591783) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
          Length = 251

 Score = 75.9 bits (185), Expect = 8e-13
 Identities = 43/123 (34%), Positives = 67/123 (53%), Gaps = 2/123 (1%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           I +EIGFG G HLI  A  +P    +G+E    S+A+ L QIE   ++N+ +   D   V
Sbjct: 79  IRLEIGFGGGEHLIHRAAEDPATGFIGVEPFVNSMAKLLGQIEAKAIRNIRLYDDDATQV 138

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           L+ +P    ++I + +P PW ++KH  RR +S+  L+   R+LKP G     +D   Y  
Sbjct: 139 LDWLPAASVDQIDLLYPDPWPKRKHWKRRFVSQINLDRFARILKPGGLFCFASDIDSYIN 198

Query: 239 DSL 241
            +L
Sbjct: 199 WTL 201
>sp|Q9F411|MT04_MYCHO Hypothetical methyltransferase MG347 homolog
 gb|AAG28841.1| (U59880) MG347-like protein [Mycoplasma hominis]
          Length = 202

 Score = 74.7 bits (182), Expect = 2e-12
 Identities = 55/178 (30%), Positives = 95/178 (52%), Gaps = 11/178 (6%)

Query: 109 TFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLK 168
           TF+DF   N+   ++EIG G G  L +LA  +P    +G+E ++     ALK+   L+L+
Sbjct: 19  TFKDFPIDNKKNTILEIGMGRGTMLTKLALMHPDIEYIGLEKYSTPAYSALKKAIDLNLE 78

Query: 169 NLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGF 226
           N HI+ GD  + L +   ++ + I++ F  PW +K+H  RR++   FL     VL   G 
Sbjct: 79  NFHIIIGDA-INLSTYFKNKIKTIWLTFSDPWPKKRHYKRRLVYRDFLKIYQNVLDKDGV 137

Query: 227 LELRTDDSLYFEDSLKLALKNFQCEIEIKK------NAQIP-VVSKYEARWNKLKKDI 277
           +  +TD+ + ++ ++   LK    +I  +       N +I  V + YE ++NKL K+I
Sbjct: 138 VYFKTDNDMLYQFAID-ELKEINAKIIYQTSDLHHCNFKIENVFTDYEEKFNKLNKNI 194
>ref|NP_244127.1| (NC_002570) BH3261~unknown conserved protein [Bacillus halodurans]
 sp|Q9K7U8|MT04_BACHD Hypothetical methyltransferase BH3261
 dbj|BAB06980.1| (AP001518) BH3261~unknown conserved protein [Bacillus halodurans]
          Length = 220

 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 49/169 (28%), Positives = 89/169 (51%), Gaps = 9/169 (5%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           QAP+ IE+G G G+ L  +AK++P    +GIE +   +  A+++ +  +L NL  L  D 
Sbjct: 38  QAPLYIEVGTGKGQFLTGMAKHHPEINFIGIERYESVLVTAMERAKEAELTNLKFLSEDV 97

Query: 178 RLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSL 235
             +L+   +    ++F++F  PW +K+H  RR+  + FL +   VLK +G +  +TD+  
Sbjct: 98  YDLLDFFADGEVSRLFINFTDPWPKKRHEKRRLTYKDFLAKYEIVLKEKGDIHFKTDNQG 157

Query: 236 YFEDSLK------LALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIY 278
            FE SL       + L N   ++    + +  + ++YE ++ K    IY
Sbjct: 158 LFEYSLHSFSKYGMILHNVSLDLH-NSDFEGNIKTEYEEKFAKKGMRIY 205
>ref|NP_390868.1| (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
 sp|O34522|MT04_BACSU Hypothetical methyltransferase ytmQ
 pir||B69997 conserved hypothetical protein ytmQ - Bacillus subtilis
 gb|AAC00285.1| (AF008220) YtmQ [Bacillus subtilis]
 emb|CAB14968.1| (Z99119) similar to hypothetical proteins [Bacillus subtilis]
          Length = 213

 Score = 73.6 bits (179), Expect = 4e-12
 Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 12/179 (6%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IE+G G G+ +  +AK NP    +GIE+    I  A+++++  + +N+ +L  D
Sbjct: 37  NDNPIHIEVGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNID 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
              + +       ++++++F  PW +K+H  RR+    FL +   V+   G +  +TD+ 
Sbjct: 97  ADTLTDVFEPGEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNR 156

Query: 235 LYFEDSLK------LALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRIYSLEW 287
             FE SLK      L L     ++    N +  ++++YE +++ L + IY   +   EW
Sbjct: 157 GLFEYSLKSFSEYGLLLTYVSLDLH-NSNLEGNIMTEYEEKFSALGQPIYRAEV---EW 211
>ref|NP_073017.1| (NC_000908) conserved hypothetical protein [Mycoplasma genitalium]
 sp|P47589|MT04_MYCGE Hypothetical methyltransferase MG347
 pir||D64238 hypothetical protein homolog MG347 - Mycoplasma genitalium
 gb|AAC71572.1| (U39716) conserved hypothetical protein [Mycoplasma genitalium]
          Length = 210

 Score = 73.6 bits (179), Expect = 4e-12
 Identities = 53/184 (28%), Positives = 94/184 (50%), Gaps = 12/184 (6%)

Query: 111 EDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLD--LK 168
           + F +  +  +++E+G G G  LI+ A+ N     +GIE     + +A+ +I  LD  L+
Sbjct: 23  DKFAKFTKKQLVLELGCGKGTFLIKEAQKNNNFLFIGIEREPTIVLKAINKINKLDFNLE 82

Query: 169 NLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGF 226
           N+ +L  D + + +       +KIF++FP PW +K+H  RR+ S  FL     +L   G 
Sbjct: 83  NILLLCTDAKQLDDYFQAESVQKIFINFPDPWPKKRHIQRRLTSPDFLKLFWNLLVKNGL 142

Query: 227 LELRTDDSLYFEDSLKLALKNFQC-----EIEIKKNAQIPV---VSKYEARWNKLKKDIY 278
           +E +TD+   FE +L    +N Q      +I    N++      +++YE R+ +L+  I 
Sbjct: 143 IEFKTDNDKLFEYTLTTLQENSQIFEIIHQITDLNNSEFSFQNSITEYEQRFMELEIPIK 202

Query: 279 DLRI 282
            L I
Sbjct: 203 KLVI 206
>ref|NP_518824.1| (NC_003295) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
 emb|CAD14233.1| (AL646060) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
          Length = 251

 Score = 72.0 bits (175), Expect = 1e-11
 Identities = 51/165 (30%), Positives = 77/165 (45%), Gaps = 6/165 (3%)

Query: 122 LIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLVL 181
           + EIGFG G     +A+  P    LG+E+H P +   LK I    + N+ I+  D   VL
Sbjct: 80  IFEIGFGMGETSAHIAQLRPDDDFLGVEVHEPGVGALLKLIGERGIGNVRIVSHDAVEVL 139

Query: 182 ESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
             M P    + I V FP PW++K+H  RR++   F+      L+P G+L   TD   Y  
Sbjct: 140 AQMIPEGTLDGIHVFFPDPWHKKRHNKRRLIQGPFVARLAAHLRPGGYLHCATDWEEYAH 199

Query: 239 DSLKLALKNFQCEIEIKKNAQIP---VVSKYEARWNKLKKDIYDL 280
             L++       E      A  P    V+K+E R  +L   ++D+
Sbjct: 200 QMLEVLSAEPLLENTADGFAPRPDYRPVTKFEKRGLRLGHGVWDV 244
>ref|NP_110210.1| (NC_000912) similar to methyltransferase [Mycoplasma pneumoniae]
 sp|P75256|MT04_MYCPN Hypothetical methyltransferase MG347 homolog (G12_orf210V)
 pir||S73646 hypothetical protein HI0340 - Mycoplasma pneumoniae (strain ATCC
           29342)
 gb|AAB95968.1| (AE000029) similar to methyltransferase [Mycoplasma pneumoniae]
          Length = 210

 Score = 71.6 bits (174), Expect = 1e-11
 Identities = 42/130 (32%), Positives = 72/130 (55%), Gaps = 4/130 (3%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLK--NLHILQGDGR 178
           + +EIG G    L + A+ NP    +GIE     + +A+ ++  L++K  NL I   D  
Sbjct: 33  LFVEIGCGKSWFLSQQAQQNPKCFFVGIEREPTIVLKAINKVNRLEVKPRNLLITCLDAN 92

Query: 179 LVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
            + E +      KIF++FP PW +K+H  RR+ +  FL +  ++LK +G +E +TD+   
Sbjct: 93  QLTEYLKPQSISKIFINFPDPWPKKRHTLRRLTAPHFLKQFHQLLKKQGLIEFKTDNDQL 152

Query: 237 FEDSLKLALK 246
           FE +L++  K
Sbjct: 153 FEFTLEVLQK 162
>ref|NP_470992.1| (NC_003212) similar to unknown proteins [Listeria innocua]
 emb|CAC96887.1| (AL596169) similar to unknown proteins [Listeria innocua]
          Length = 214

 Score = 71.6 bits (174), Expect = 1e-11
 Identities = 43/127 (33%), Positives = 68/127 (52%), Gaps = 2/127 (1%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IEIG G G+ +  +AK NP    +GIE+    +  AL +    ++ NL ++  D
Sbjct: 37  NNNPIHIEIGSGKGQFISGMAKANPEINYIGIEMIESVLVSALDKAIEAEVPNLRLVARD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
            +L+ ES       +I+++F  PW +K+H  RR+ +  FL    R+L   G +  +TD+ 
Sbjct: 97  AKLLEESFEKGEIAQIYLNFSDPWPKKRHTKRRLTNPTFLTIYERLLPKAGEIHFKTDNR 156

Query: 235 LYFEDSL 241
             FE SL
Sbjct: 157 SLFEYSL 163
>ref|NP_658728.1| (NC_003995) Methyltransf_4, Putative methyltransferase [Bacillus
           anthracis A2012] [Bacillus anthracis str. A2012]
          Length = 217

 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 2/127 (1%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N+ PI IE+G G GR + ++AK NP    +GIE  T  +  AL ++   +L NL ++  D
Sbjct: 37  NEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
              +         ++++++F  PW +K+H  RR+  + FL     VL   G +  +TD+ 
Sbjct: 97  AEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQ 156

Query: 235 LYFEDSL 241
             FE SL
Sbjct: 157 GLFEYSL 163
>ref|NP_465140.1| (NC_003210) similar to unknown proteins [Listeria monocytogenes
           EGD-e]
 emb|CAC99693.1| (AL591980) similar to unknown proteins [Listeria monocytogenes]
          Length = 214

 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 42/127 (33%), Positives = 68/127 (53%), Gaps = 2/127 (1%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IEIG G G+ +  +AK NP    +GIE+    +  AL +   +D+ NL ++  D
Sbjct: 37  NDNPIHIEIGSGKGQFISGMAKANPEINYIGIEMIESVLVSALDKAIEVDVPNLRLVARD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
            +L+ +        +I+++F  PW +K+H  RR+ +  FL    R+L   G +  +TD+ 
Sbjct: 97  AKLLEDCFEKGEIAQIYLNFSDPWPKKRHTKRRLTNPTFLTIYERLLPKAGEIHFKTDNR 156

Query: 235 LYFEDSL 241
             FE SL
Sbjct: 157 SLFEYSL 163
>ref|NP_345067.1| (NC_003028) conserved hypothetical protein [Streptococcus
           pneumoniae TIGR4]
 ref|NP_358070.1| (NC_003098) Conserved hypothetical protein [Streptococcus
           pneumoniae R6]
 gb|AAK74707.1| (AE007365) conserved hypothetical protein [Streptococcus pneumoniae
           TIGR4]
 gb|AAK99280.1| (AE008427) Conserved hypothetical protein [Streptococcus pneumoniae
           R6]
          Length = 211

 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 38/127 (29%), Positives = 70/127 (54%), Gaps = 2/127 (1%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI +E+G G G  +  +AK NP    +GI+I    ++ AL ++  + + N+ +L  D
Sbjct: 37  NDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
           G  + +   +   ++++++F  PW +K+H  RR+  + FL+   R+L   G +  +TD+ 
Sbjct: 97  GSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNR 156

Query: 235 LYFEDSL 241
             FE SL
Sbjct: 157 GLFEYSL 163
>ref|NP_628290.1| (NC_003888) conserved hypothetical protein [Streptomyces coelicolor
           A3(2)]
 sp|Q9F305|MT04_STRCO Hypothetical methyltransferase SCO4111
 emb|CAC08407.1| (AL392177) conserved hypothetical protein [Streptomyces coelicolor
           A3(2)]
          Length = 271

 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 7/144 (4%)

Query: 101 GKKTLDLGTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALK 160
           G++ +DL      +  N  P+++EIGFG G     +A  +P    L  ++HTP     L 
Sbjct: 74  GRRVVDLAE----LFGNARPVVLEIGFGMGETTARMAAADPDTNILAADVHTPGQGNLLG 129

Query: 161 QIELLDLKNLHILQGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEA 217
             E  +L N+ +  GD  ++L E +       + V+FP PW +K+H  RR++  +FL  A
Sbjct: 130 LAERQELPNIRVANGDAIILLREMLAPGSLAGLRVYFPDPWPKKRHHKRRLIQPEFLTLA 189

Query: 218 LRVLKPRGFLELRTDDSLYFEDSL 241
              L P   +   TD   Y E  L
Sbjct: 190 ATRLAPGAVVHCATDWEPYAEQML 213
>ref|NP_353395.1| (NC_003062) AGR_C_634p [Agrobacterium tumefaciens] [Agrobacterium
           tumefaciens str. C58 (Cereon)]
 ref|NP_531069.1| (NC_003304) conserved hypothetical protein [Agrobacterium
           tumefaciens str. C58 (U. Washington)]
 gb|AAK86180.1| (AE007974) AGR_C_634p [Agrobacterium tumefaciens str. C58 (Cereon)]
 gb|AAL41385.1| (AE009007) conserved hypothetical protein [Agrobacterium
           tumefaciens str. C58 (U. Washington)]
          Length = 232

 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 42/124 (33%), Positives = 63/124 (49%), Gaps = 2/124 (1%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           I +EIGFG G HL   A  NP    +G+E    S+A+ L  +   +L N+ +   D   +
Sbjct: 60  IRLEIGFGGGEHLAHRAVENPETGFIGVEPFVNSMAKLLATVRERELMNIRLYDDDATQL 119

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           L+ +P    + I + +P PW +KKH  RR +S+  L    RVLKP G     +D   Y  
Sbjct: 120 LDWLPEGSIDHIDLLYPDPWPKKKHWKRRFVSDVNLARFHRVLKPGGKFCFASDIDTYVN 179

Query: 239 DSLK 242
            +L+
Sbjct: 180 WTLQ 183
>ref|NP_607764.1| (NC_003485) putative methyltransferase [Streptococcus pyogenes
           MGAS8232]
 gb|AAL98263.1| (AE010083) putative methyltransferase [Streptococcus pyogenes
           MGAS8232]
          Length = 211

 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 45/170 (26%), Positives = 86/170 (50%), Gaps = 9/170 (5%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IE+G G G  +  +A  NP    +GI+I    ++ AL ++   ++ N+ +L+ D
Sbjct: 37  NDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
           G  +     +   + ++++F  PW + KH  RR+  + FL+   R+L   G +  +TD+ 
Sbjct: 97  GSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNR 156

Query: 235 LYFEDSLK------LALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIY 278
             FE SL       + L+    ++    N +  V+++YE +++   + IY
Sbjct: 157 GLFEYSLASFSQYGMTLRQIWLDLH-ASNYEGNVMTEYEEKFSNKGQVIY 205
>ref|NP_269750.1| (NC_002737) conserved hypothetical protein [Streptococcus pyogenes]
           [Streptococcus pyogenes M1 GAS]
 sp|P58090|MT04_STRPY Hypothetical methyltransferase SPy1726
 gb|AAK34471.1| (AE006601) conserved hypothetical protein [Streptococcus pyogenes
           M1 GAS]
          Length = 211

 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 45/170 (26%), Positives = 86/170 (50%), Gaps = 9/170 (5%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IE+G G G  +  +A  NP    +GI+I    ++ AL ++   ++ N+ +L+ D
Sbjct: 37  NDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
           G  +     +   + ++++F  PW + KH  RR+  + FL+   R+L   G +  +TD+ 
Sbjct: 97  GSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNR 156

Query: 235 LYFEDSLK------LALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIY 278
             FE SL       + L+    ++    N +  V+++YE +++   + IY
Sbjct: 157 GLFEYSLASFSQYGMTLRQIWLDLH-ASNYEGNVMTEYEEKFSNKGQVIY 205
>ref|NP_266905.1| (NC_002662) HYPOTHETICAL PROTEIN [Lactococcus lactis subsp. lactis]
 sp|Q9CHI2|MT04_LACLA Hypothetical methyltransferase yhfE
 gb|AAK04847.1|AE006308_7 (AE006308) HYPOTHETICAL PROTEIN [Lactococcus lactis subsp. lactis]
          Length = 217

 Score = 68.9 bits (167), Expect = 9e-11
 Identities = 46/174 (26%), Positives = 92/174 (52%), Gaps = 11/174 (6%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI IE+G G G  +  +A  +P    + I++    ++ AL +    DL N+ ++  D
Sbjct: 37  NDHPIHIEVGCGKGAFITGMAALHPEINYIAIDMQLSVLSYALDKAIEADLPNVQMMLVD 96

Query: 177 GRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDS 234
           G  + E   +   ++++++F  PW + +H  RR+  + FL    ++L+P G +  +TD+ 
Sbjct: 97  GAALSEYFADGEIDQVYLNFSDPWPKGRHEKRRLTYKSFLATYEKILRPEGEIHFKTDNR 156

Query: 235 LYFEDSLKLALKNFQCEI--------EIKKNAQIPVVSKYEARWNKLKKDIYDL 280
             FE SL ++L N+  E+        + ++ A   V+++YE ++++  + IY L
Sbjct: 157 GLFEYSL-VSLANYGMELKKVWLDLHQDEEFAPQNVMTEYEQKFSQKGQVIYRL 209
>ref|NP_218905.1| (NC_000919) conserved hypothetical protein [Treponema pallidum]
 sp|O83477|MT04_TREPA Hypothetical methyltransferase TP0464
 pir||B71321 conserved hypothetical protein TP0464 - syphilis spirochete
 gb|AAC65448.1| (AE001223) conserved hypothetical protein [Treponema pallidum]
          Length = 250

 Score = 68.9 bits (167), Expect = 9e-11
 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 3/121 (2%)

Query: 119 APILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGR 178
           AP+++EIGFG G     +A  NP  + LGIE++   I + L++IE   L NL I++ D  
Sbjct: 81  APLVVEIGFGMGSATAAIAARNPHLSYLGIEVYRAGIGRLLRKIEAERLHNLRIIEHDAL 140

Query: 179 LVLESM-PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSL 235
            VL +M        + + FP PW + +H  RR+L     +   R L P G+L   TD + 
Sbjct: 141 DVLRTMIAPQTLAGLHIFFPDPWPKTRHHKRRLLYRPRTDLLARALAPGGYLYAVTDWAE 200

Query: 236 Y 236
           Y
Sbjct: 201 Y 201
>ref|NP_638497.1| (NC_003902) DNA mismatch repair protein [Xanthomonas campestris pv.
           campestris str. ATCC 33913]
 gb|AAM42421.1| (AE012430) DNA mismatch repair protein [Xanthomonas campestris pv.
           campestris str. ATCC 33913]
          Length = 261

 Score = 68.2 bits (165), Expect = 2e-10
 Identities = 52/192 (27%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 112 DFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLH 171
           D +    AP ++EIGFG+G  L   A+++P +  +GIE+H P + + L  ++     ++ 
Sbjct: 63  DAVFGRPAPKVLEIGFGNGAALRFAAQHDPARDYIGIEVHAPGVGRLLNALDDDGATHVR 122

Query: 172 ILQGDGRLVLE-SMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLE 228
           +   D   VLE  + +   +++ ++FP PW++K+H  RR++   F    +R L+  G L 
Sbjct: 123 LYHHDAVEVLEREIADGALDEVRIYFPDPWHKKRHNKRRLVQPAFAQLLVRKLRDGGRLH 182

Query: 229 LRTDDSLYFE------DSLKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDL-- 280
             TD + Y E      D+ +  +        + + A  P  + +E R  KL   ++DL  
Sbjct: 183 AATDWADYAEQMWDVLDATEGLVNRAGPRGHVARPAWRP-QTHFETRGQKLGHGVWDLLY 241

Query: 281 -RIYSLEWNETP 291
            R   +E  E+P
Sbjct: 242 DRESGMENRESP 253
>ref|NP_349234.1| (NC_003030) Predicted S-adenosylmethionine-dependent
           methyltransferase, YtmQ B.subtilis ortholog [Clostridium
           acetobutylicum]
 gb|AAK80574.1|AE007760_4 (AE007760) Predicted S-adenosylmethionine-dependent
           methyltransferase, YtmQ B.subtilis ortholog [Clostridium
           acetobutylicum]
          Length = 211

 Score = 65.9 bits (159), Expect = 8e-10
 Identities = 46/168 (27%), Positives = 80/168 (47%), Gaps = 13/168 (7%)

Query: 116 KNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQG 175
           KN   I +E+G G G  +  +A  +P K  + I++    IA AL++I   +++N+ I   
Sbjct: 35  KNDNEIYLELGCGRGDFVTNIANKHPEKNYVAIDLKDEVIAIALRKITESEVQNVRIAPL 94

Query: 176 DGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDD 233
               + E        +I+++F  PW + +H  RR+   KFL +    LKP   +  +TDD
Sbjct: 95  QIAFINEVFDKDEIARIYINFCNPWPKDRHKKRRLTHTKFLTKYKEFLKPNSQIWFKTDD 154

Query: 234 SLYFEDSLKLALKNFQCEIEI--------KKNAQIPVVSKYEARWNKL 273
              F +SL       +C  +I        K      +V++YE+++ KL
Sbjct: 155 DGLFVESLDYFK---ECGFQIKFMTYDLHKSGFDKNIVTEYESKFLKL 199
>ref|NP_643610.1| (NC_003919) DNA mismatch repair protein [Xanthomonas axonopodis pv.
           citri str. 306]
 gb|AAM38146.1| (AE011975) DNA mismatch repair protein [Xanthomonas axonopodis pv.
           citri str. 306]
          Length = 261

 Score = 65.5 bits (158), Expect = 1e-09
 Identities = 37/120 (30%), Positives = 67/120 (55%), Gaps = 3/120 (2%)

Query: 122 LIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLVL 181
           ++EIGFG+G  L   A+ +P++  +GIE+H P + + L  +E     ++ +   D   VL
Sbjct: 73  VLEIGFGNGAALRFAAQQDPSRDYIGIEVHAPGVGRLLNALEEDGSTHVRLYHHDAVEVL 132

Query: 182 E-SMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
           E  + +   +++ ++FP PW++K+H  RR++   F    +R L+  G L   TD + Y E
Sbjct: 133 EHEIADGALDEVRIYFPDPWHKKRHNKRRLIQPAFAQLLVRKLREGGRLHAATDWADYAE 192
>ref|NP_078103.1| (NC_002162) conserved hypothetical [Ureaplasma urealyticum]
 sp|Q9PQM2|MT04_UREPA Hypothetical methyltransferase UU269
 pir||G82913 conserved hypothetical UU269 [imported] - Ureaplasma urealyticum
 gb|AAF30678.1|AE002123_11 (AE002123) conserved hypothetical [Ureaplasma urealyticum]
          Length = 224

 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 40/122 (32%), Positives = 63/122 (50%), Gaps = 2/122 (1%)

Query: 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG 177
           + P+ IEIG G G  +IE A  N     LGIE     I +A K+     L NL ++  D 
Sbjct: 39  ELPLYIEIGMGKGDFIIENALRNQQINYLGIEKFPTVIVKAHKKALKHKLDNLAMICFDA 98

Query: 178 RLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSL 235
             +LE + +   +KI+++F  PW +K+H  +R+    FL +   +LK    +E +TD+  
Sbjct: 99  NKILELLNSESVDKIYLNFSDPWPKKRHAKKRLTHPCFLEKFAVILKQNALVEFKTDNEN 158

Query: 236 YF 237
            F
Sbjct: 159 LF 160
>ref|NP_295403.1| (NC_001263) conserved hypothetical protein [Deinococcus
           radiodurans]
 sp|Q9RTS6|MT04_DEIRA Hypothetical methyltransferase DR1680
 pir||F75365 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1)
 gb|AAF11238.1|AE002010_1 (AE002010) conserved hypothetical protein [Deinococcus radiodurans]
          Length = 322

 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 68/252 (26%), Positives = 108/252 (41%), Gaps = 27/252 (10%)

Query: 120 PILIEIGFGSGRHLIELAKNNPTK-TCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGR 178
           P ++EIGFG GR     A+  P     LG+EI   S+ +A ++++   L N  + +    
Sbjct: 25  PWVLEIGFGDGRFWPHYARTFPEPPNYLGVEISGVSLLKAHRRLKDAGLTNAVLTKLPAE 84

Query: 179 -LVLESMPNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGFLELRTDDSL 235
            LV + +P+   + I V+FP PW +  H   R+L   F   A   LKP G   L TD   
Sbjct: 85  VLVAQVIPHGSLDAIIVNFPDPWPKAGHEDHRLLRVPFFQVAASRLKPGGAALLTTDHDE 144

Query: 236 YFEDSLKLALKNFQCEIEIKKNAQIPVVSKYEARWNKLKKDIYDLRI------------Y 283
           YFE +   A  +    +E        + +KY  +W  L   +   R             +
Sbjct: 145 YFEFACAQAEASGVMRVERVGPPPAALETKYAQKWRDLGLGVNHARFVPTRHDPVPNGTF 204

Query: 284 SLEWNETPFDNHAF-----DFS---FDTITISKKS-VGTILKTKKIIQEGYFVHVCNIYE 334
           +    E P   HA      DFS   FD +T+  K+    +L     ++ G +V + ++ E
Sbjct: 205 APYSEEDPAVPHAVLTLPADFSPQHFDKLTVRGKTWTVVLLDLYATLRRGGWVALAHVVE 264

Query: 335 NKGDFLVELSMG 346
             GD   E+ +G
Sbjct: 265 --GDLTQEVLVG 274
>ref|NP_106193.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
 dbj|BAB51979.1| (AP003006) hypothetical protein [Mesorhizobium loti]
          Length = 247

 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 2/118 (1%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           + +EIGFG G HL+  A   PT   +G+E     +A+ +  +    L NL +   D   +
Sbjct: 75  VRLEIGFGGGEHLLHRAIEAPTTGFIGVEPFVNGMAKMMMAVRARPLANLRVHDDDATRL 134

Query: 181 LESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLY 236
           L+ +P      I + +P PW +KKH  RR +S   L    RVLKP       +D   Y
Sbjct: 135 LDWLPPASLGGIDLLYPDPWPKKKHWKRRFVSPVNLERFARVLKPGAKFRFASDIDTY 192
>ref|NP_602057.1| (NC_003450) COG0220:Predicted S-adenosylmethionine-dependent
           methyltransferase [Corynebacterium glutamicum]
 dbj|BAC00259.1| (AP005283) Predicted S-adenosylmethionine-dependent
           methyltransferase [Corynebacterium glutamicum ATCC
           13032]
          Length = 255

 Score = 62.8 bits (151), Expect = 7e-09
 Identities = 45/158 (28%), Positives = 78/158 (48%), Gaps = 11/158 (6%)

Query: 92  LQENSKHASGKKTLDLG-TFED-------FIQKNQAPILIEIGFGSGRHLIELAKNNPTK 143
           L EN +    +K  +LG   ED       +  +  A  ++EIG G+G     +A      
Sbjct: 43  LTENQQTMWDEKWPELGRVLEDELIDVDAWFGREGAKTIVEIGSGTGTSTAAMAPLEADT 102

Query: 144 TCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLVLESM-PNHRCEKIFVHFPVPWNE 202
             + +E++ P +A+ +  +   ++ N+ +++GDG  VL  M  +   + I V+FP PW +
Sbjct: 103 NIVAVELYKPGLAKLMGSVVRGEIDNVRMVRGDGIEVLNRMFADGSLDGIRVYFPDPWPK 162

Query: 203 KKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
            +H  RR++    LN   + LKP G L + TD + Y E
Sbjct: 163 ARHNKRRIIQSGPLNLFAKKLKPGGVLHVATDHADYAE 200
>ref|NP_298074.1| (NC_002488) conserved hypothetical protein [Xylella fastidiosa
           9a5c]
 sp|Q9PF94|MT04_XYLFA Hypothetical methyltransferase XF0784
 pir||G82761 conserved hypothetical protein XF0784 [imported] - Xylella
           fastidiosa (strain 9a5c)
 gb|AAF83594.1|AE003919_5 (AE003919) conserved hypothetical protein [Xylella fastidiosa 9a5c]
          Length = 244

 Score = 62.4 bits (150), Expect = 9e-09
 Identities = 45/177 (25%), Positives = 85/177 (47%), Gaps = 8/177 (4%)

Query: 112 DFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLH 171
           D +    AP ++E+GFG+G  L   A++ P    +GIE++ P + + L  +     +++ 
Sbjct: 63  DVLFGRSAPKVLEVGFGNGAALRFAAQHEPRYDYIGIEVYAPGVGRLLNGLAEDGSRHVR 122

Query: 172 ILQGDGRLVL-ESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLE 228
           +   D   VL + + +   ++I ++FP PW++K+H  RR++   F    +R L+  G L 
Sbjct: 123 LYHYDAVEVLNKEIVDGALDEIRIYFPDPWHKKRHHKRRLIQPLFATLLVRKLRVGGCLH 182

Query: 229 LRTDDSLYFEDSLKLALKNFQCEIEIKKNAQIP-----VVSKYEARWNKLKKDIYDL 280
           + TD + Y E    +               Q+P     V +++E R   L   ++DL
Sbjct: 183 MATDWADYAEQMWDVLDATPGLVNRAGLRGQVPCPDWRVQTRFERRGQNLGHRVWDL 239
>ref|NP_540886.1| (NC_003317) SAM-DEPENDENT METHYLTRANSFERASE [Brucella melitensis]
 gb|AAL53150.1| (AE009630) SAM-DEPENDENT METHYLTRANSFERASE [Brucella melitensis]
          Length = 233

 Score = 60.8 bits (146), Expect = 3e-08
 Identities = 43/145 (29%), Positives = 70/145 (47%), Gaps = 7/145 (4%)

Query: 105 LDLGTF--EDFIQKNQAPI---LIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQAL 159
           LDL T   +D     +AP+    +EIGFG G HL   +   P    +G+E     +A+ L
Sbjct: 40  LDLATPAPQDLRSLFEAPVETVRMEIGFGGGEHLHHESGRYPQSGFIGVEPFINGMAKML 99

Query: 160 KQIELLDLKNLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEA 217
             ++     NL +   D   VL+ +P+     I + +P PW++++H  RR +S+  L+  
Sbjct: 100 AALDQAPRPNLRLYDEDATAVLDWLPDASLAGIDLFYPDPWHKRRHWKRRFVSDANLDRF 159

Query: 218 LRVLKPRGFLELRTDDSLYFEDSLK 242
            RVLKP       +D   Y   +L+
Sbjct: 160 ARVLKPGAKFRFASDIEHYVNWTLQ 184
>sp|P73161|MT04_SYNY3 Hypothetical methyltransferase sll1300
          Length = 211

 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 40/132 (30%), Positives = 69/132 (51%), Gaps = 8/132 (6%)

Query: 106 DLGTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELL 165
           D  T  D +Q+   P+ ++IG   GR  +++A+ +P    LG+EI  P + +A +  + L
Sbjct: 25  DWATVYDDVQR---PLHLDIGCARGRFPLKMAQQHPDWNFLGVEIRQPLVLEANETGDRL 81

Query: 166 DLKNLHILQGDGRLVLE---SMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRV 220
            LKNLH L G+  +  E   S      +++ + FP PW +++H  RRV   + +      
Sbjct: 82  GLKNLHYLFGNINVEPEKFFSAFPPTLQRVSIQFPDPWFKQRHNKRRVAQPELVTAIANA 141

Query: 221 LKPRGFLELRTD 232
           L P G + L++D
Sbjct: 142 LPPGGEVLLQSD 153
>ref|NP_646508.1| (NC_003923) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus MW2]
 dbj|BAB95556.1| (AP004828) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus MW2]
          Length = 214

 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 3/137 (2%)

Query: 108 GTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDL 167
           G   ++  K Q PI IEIG G G+ +  LA  NP    + +E     + + L +++ + L
Sbjct: 28  GKMTEWFDKTQ-PIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMSL 86

Query: 168 KNLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRG 225
            NL I+  D   + E   +    +I+++F  PW + +H  RR+    FL    ++L   G
Sbjct: 87  TNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEG 146

Query: 226 FLELRTDDSLYFEDSLK 242
            L  +TD+   F  SL+
Sbjct: 147 DLHFKTDNRGLFAYSLE 163
>ref|NP_440507.1| (NC_000911) hypothetical protein [Synechocystis sp. PCC 6803]
 pir||S75273 hypothetical protein sll1300 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA17187.1| (D90904) ORF_ID:sll1300~hypothetical protein [Synechocystis sp. PCC
           6803]
          Length = 192

 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 40/132 (30%), Positives = 69/132 (51%), Gaps = 8/132 (6%)

Query: 106 DLGTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELL 165
           D  T  D +Q+   P+ ++IG   GR  +++A+ +P    LG+EI  P + +A +  + L
Sbjct: 6   DWATVYDDVQR---PLHLDIGCARGRFPLKMAQQHPDWNFLGVEIRQPLVLEANETGDRL 62

Query: 166 DLKNLHILQGDGRLVLE---SMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRV 220
            LKNLH L G+  +  E   S      +++ + FP PW +++H  RRV   + +      
Sbjct: 63  GLKNLHYLFGNINVEPEKFFSAFPPTLQRVSIQFPDPWFKQRHNKRRVAQPELVTAIANA 122

Query: 221 LKPRGFLELRTD 232
           L P G + L++D
Sbjct: 123 LPPGGEVLLQSD 134
>sp|Q9KWZ4|MT04_STAAU Hypothetical methyltransferase
 emb|CAB82477.1| (Y14816) hypothetical protein [Staphylococcus aureus]
          Length = 214

 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 3/137 (2%)

Query: 108 GTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDL 167
           G   ++  K Q PI IEIG G G+ +  LA  NP    + +E     + + L +++ + L
Sbjct: 28  GKMTEWFDKTQ-PIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGL 86

Query: 168 KNLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRG 225
            NL I+  D   + E   +    +I+++F  PW + +H  RR+    FL    ++L   G
Sbjct: 87  TNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEG 146

Query: 226 FLELRTDDSLYFEDSLK 242
            L  +TD+   F  SL+
Sbjct: 147 DLHFKTDNRGLFAYSLE 163
>ref|NP_372272.1| (NC_002758) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus Mu50]
 ref|NP_374858.1| (NC_002745) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus N315]
 dbj|BAB42837.1| (AP003134) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus N315]
 dbj|BAB57910.1| (AP003363) conserved hypothetical protein [Staphylococcus aureus
           subsp. aureus Mu50]
          Length = 214

 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 3/137 (2%)

Query: 108 GTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDL 167
           G   ++  K Q PI IEIG G G+ +  LA  NP    + +E     + + L +++ + L
Sbjct: 28  GEMTEWFDKTQ-PIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGL 86

Query: 168 KNLHILQGDGRLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRG 225
            NL I+  D   + E   +    +I+++F  PW + +H  RR+    FL    ++L   G
Sbjct: 87  TNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEG 146

Query: 226 FLELRTDDSLYFEDSLK 242
            L  +TD+   F  SL+
Sbjct: 147 DLHFKTDNRGLFAYSLE 163
>ref|NP_296595.1| (NC_002620) conserved hypothetical protein [Chlamydia muridarum]
 sp|Q9PL91|MT04_CHLMU Hypothetical methyltransferase TC0216
 pir||F81726 conserved hypothetical protein TC0216 [imported] - Chlamydia
           muridarum (strain Nigg)
 gb|AAF39088.1| (AE002289) conserved hypothetical protein [Chlamydia muridarum]
          Length = 224

 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 35/132 (26%), Positives = 68/132 (51%), Gaps = 3/132 (2%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N+ P+  E+  G+G  ++E A  + +   + +E     + +   ++    + NL I+ G+
Sbjct: 47  NEGPVCCELCSGNGDWVVEQALKDTSINWIAVEKRFDRVRKIWSKMSNHKVNNLLIVCGE 106

Query: 177 GRLVLES-MPNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGFLELRTDD 233
            +      + +   +KI V+FP PW + +HR  R+  + F+ + +RVL   G L L TDD
Sbjct: 107 AQTFFTHYVTDASFQKIVVNFPDPWPKFRHRKHRLFQDVFVQDMVRVLVEGGQLTLVTDD 166

Query: 234 SLYFEDSLKLAL 245
             Y  +S+++ L
Sbjct: 167 HTYLTNSIQVML 178
>ref|NP_485885.1| (NC_003272) hypothetical protein [Nostoc sp. PCC 7120]
 dbj|BAB73544.1| (AP003587) ORF_ID:alr1845~hypothetical protein [Nostoc sp. PCC
           7120]
          Length = 219

 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 33/119 (27%), Positives = 62/119 (51%), Gaps = 6/119 (5%)

Query: 120 PILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDG-- 177
           P+ ++IG   GR ++++A+  P    LG+EI    + +A +    L L NLH L  +   
Sbjct: 43  PLHLDIGCARGRFVLQMAQVEPNWNFLGLEIRESLVIEANQFRSQLGLTNLHYLYCNANN 102

Query: 178 --RLVLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTD 232
             + +L S+P    +++ + FP PW + +H  RRV+  + + +    L   G + L++D
Sbjct: 103 SLQPLLSSLPTGILQRVTIQFPDPWFKTRHAKRRVVQPELVQDIANYLAVGGVVFLQSD 161
>dbj|BAB09565.1| (AB006706) gb|AAB08476.1~gene_id:MVA3.1~similar to unknown protein
           [Arabidopsis thaliana]
          Length = 280

 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 95  NSKHASGKKTLDLGTFEDFIQKNQAPILIEIGFGSGRHLI-ELAKNNPTKTCLGIEIHTP 153
           N   +S  K   +  +++  +    P++++IG GSGR L+ +  KN  ++  LG+EI   
Sbjct: 69  NPLSSSFSKPAPVPVWDEVYKDPSLPLMVDIGSGSGRFLLWQANKNVESRNYLGLEIRQK 128

Query: 154 SIAQALKQIELLDLKNLHILQGDGRLVLESMPNH---RCEKIFVHFPVPWNEKKH--RRV 208
            + +A   +  L L N+H +  +  +  E + +      E + +  P P  +K+H  RRV
Sbjct: 129 LVKRANFWVNELGLSNVHFIFANAMVSFEHLISSYPGPLEIVSILCPDPHFKKRHQKRRV 188

Query: 209 LSEKFLNEALRVLKPRGFLELRTD 232
           + +  +N  L+ LKP G + +++D
Sbjct: 189 VQKPLVNSILQNLKPGGKIFVQSD 212
>ref|NP_568355.1| (NM_121772) putative protein [Arabidopsis thaliana]
 gb|AAM67168.1| (AY088862) unknown [Arabidopsis thaliana]
          Length = 312

 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 95  NSKHASGKKTLDLGTFEDFIQKNQAPILIEIGFGSGRHLI-ELAKNNPTKTCLGIEIHTP 153
           N   +S  K   +  +++  +    P++++IG GSGR L+ +  KN  ++  LG+EI   
Sbjct: 101 NPLSSSFSKPAPVPVWDEVYKDPSLPLMVDIGSGSGRFLLWQANKNVESRNYLGLEIRQK 160

Query: 154 SIAQALKQIELLDLKNLHILQGDGRLVLESMPNH---RCEKIFVHFPVPWNEKKH--RRV 208
            + +A   +  L L N+H +  +  +  E + +      E + +  P P  +K+H  RRV
Sbjct: 161 LVKRANFWVNELGLSNVHFIFANAMVSFEHLISSYPGPLEIVSILCPDPHFKKRHQKRRV 220

Query: 209 LSEKFLNEALRVLKPRGFLELRTD 232
           + +  +N  L+ LKP G + +++D
Sbjct: 221 VQKPLVNSILQNLKPGGKIFVQSD 244
>ref|NP_214722.1| (NC_000962) hypothetical protein Rv0208c [Mycobacterium
           tuberculosis H37Rv]
 ref|NP_334625.1| (NC_002755) conserved hypothetical protein [Mycobacterium
           tuberculosis CDC1551]
 sp|P96390|MT04_MYCTU Hypothetical methyltransferase Rv0208c
 pir||F70959 hypothetical protein Rv0208c - Mycobacterium tuberculosis  (strain
           H37RV)
 emb|CAB07003.1| (Z92669) hypothetical protein Rv0208c [Mycobacterium tuberculosis
           H37Rv]
 gb|AAK44439.1| (AE006931) conserved hypothetical protein [Mycobacterium
           tuberculosis CDC1551]
          Length = 263

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 39/126 (30%), Positives = 64/126 (49%), Gaps = 7/126 (5%)

Query: 119 APILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELL--DLKNLHILQGD 176
           AP+++EIG GSG   + +AK  P    + ++++   +AQ L  I+ +  D  N+ ++ G+
Sbjct: 77  APVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGN 136

Query: 177 GRLVLESM--PNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTD 232
              VL+ +  P+  C  + V FP PW + +H  RR+L    +      L P G L   TD
Sbjct: 137 AVDVLQHLIAPDSLC-GVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATD 195

Query: 233 DSLYFE 238
              Y E
Sbjct: 196 HPGYAE 201
>ref|NP_220350.1| (NC_000117) rRNA Methylase (possible) [Chlamydia trachomatis]
 pir||E71464 probable rRNA methylase - Chlamydia trachomatis (serotype D, strain
           UW3/Cx)
 gb|AAC68426.1| (AE001356) rRNA Methylase (possible) [Chlamydia trachomatis]
          Length = 187

 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 5/157 (3%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI  E+  G+G  ++E A  + +   + +E     + +   ++    + NL I+ G+
Sbjct: 10  NNGPICCELCSGNGDWVVEQALKDASVNWIAVEKRFDRVRKIWSKMGNYRVNNLLIVCGE 69

Query: 177 GRLVLES-MPNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGFLELRTDD 233
            +      + +   +KI V+FP PW + +HR  R+  + F+ + +R L   G L L TDD
Sbjct: 70  AQTFFSHYVSDASFQKIVVNFPDPWPKFRHRKHRLFQDLFVQDMMRTLVVGGQLTLATDD 129

Query: 234 SLYFEDSLKLALKNFQCEIEIKKNAQIPVVSKYEARW 270
             Y  +++ + LK       +K    I V   Y   W
Sbjct: 130 YNYLVNAITVMLK--YLSPGLKSPHYINVKDNYGGSW 164
>sp|O84836|MT04_CHLTR Hypothetical methyltransferase CT829
          Length = 224

 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 5/157 (3%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGD 176
           N  PI  E+  G+G  ++E A  + +   + +E     + +   ++    + NL I+ G+
Sbjct: 47  NNGPICCELCSGNGDWVVEQALKDASVNWIAVEKRFDRVRKIWSKMGNYRVNNLLIVCGE 106

Query: 177 GRLVLES-MPNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGFLELRTDD 233
            +      + +   +KI V+FP PW + +HR  R+  + F+ + +R L   G L L TDD
Sbjct: 107 AQTFFSHYVSDASFQKIVVNFPDPWPKFRHRKHRLFQDLFVQDMMRTLVVGGQLTLATDD 166

Query: 234 SLYFEDSLKLALKNFQCEIEIKKNAQIPVVSKYEARW 270
             Y  +++ + LK       +K    I V   Y   W
Sbjct: 167 YNYLVNAITVMLK--YLSPGLKSPHYINVKDNYGGSW 201
>sp|P72546|MT04_SYNP7 Hypothetical methyltransferase DC13
 gb|AAB08476.1| (U62616) putative protein [Synechococcus sp. PCC 7942]
          Length = 213

 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 120 PILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRL 179
           P+ ++IG   GR L+ +A   P    LG+EI  P + +A       +L NL+    +  L
Sbjct: 36  PLHLDIGCARGRFLLAMATRQPEWNYLGLEIREPLVDEANAIARERELTNLYYHFSNANL 95

Query: 180 VLE----SMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRG 225
            LE    S+P    +++ + FP PW +K+H  RRV+  + L +AL    P G
Sbjct: 96  DLEPLLRSLPTGILQRVSIQFPDPWFKKRHQKRRVVQPE-LVQALATALPAG 146
>ref|NP_225180.1| (NC_000922) predicted rRNA Methylase [Chlamydophila pneumoniae
           CWL029]
 ref|NP_301041.1| (NC_002491) rRNA methylase [Chlamydophila pneumoniae J138]
 ref|NP_445407.1| (NC_002179) conserved hypothetical protein [Chlamydophila
           pneumoniae AR39]
 sp|Q9Z6S3|MT04_CHLPN Hypothetical methyltransferase CPn0986/CP0869/CPj0986
 pir||C72010 conserved hypothetical protein CP0869 [imported] - Chlamydophila
           pneumoniae (strains CWL029 and AR39)
 gb|AAD19123.1| (AE001679) predicted rRNA Methylase [Chlamydophila pneumoniae
           CWL029]
 gb|AAF38658.1| (AE002245) conserved hypothetical protein [Chlamydophila pneumoniae
           AR39]
 dbj|BAA99193.1| (AP002548) rRNA methylase [Chlamydophila pneumoniae J138]
          Length = 224

 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 34/135 (25%), Positives = 66/135 (48%), Gaps = 4/135 (2%)

Query: 111 EDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNL 170
           ++F Q N   I  E+  G+G  ++  A+ +P    + +E     + +   ++    ++NL
Sbjct: 42  QEFFQ-NHTSIACELCSGNGDWVVAQAQKDPQVLWIAVEQRFDRVRKIWSKMINHQIQNL 100

Query: 171 HILQGDGRLVLES-MPNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGFL 227
            I+ G      +  +P+   +++ V+FP PW + +HR  R+L   F+ E  R L+     
Sbjct: 101 RIVCGTAETFFQYYVPDQFLQRLVVNFPDPWPKMRHRKHRLLQPSFVQEISRSLQDSAVF 160

Query: 228 ELRTDDSLYFEDSLK 242
            L TDD  Y  +S++
Sbjct: 161 ALATDDKTYLLESIE 175
>ref|NP_561340.1| (NC_003366) conserved hypothetical protein [Clostridium
           perfringens]
 dbj|BAB80130.1| (AP003186) conserved hypothetical protein [Clostridium perfringens]
          Length = 219

 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 41/158 (25%), Positives = 75/158 (46%), Gaps = 16/158 (10%)

Query: 108 GTFEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELL-- 165
           G +++  +  + PI +E+G G G  +     +NP    + I+I    +  A + IE    
Sbjct: 28  GNWKNTFKNTENPIYLELGCGKGTFMAVHGSDNPNINYIAIDIKDEVLVLAKRSIEKAYE 87

Query: 166 ----DLKNLHILQGDGRL---VLESMPNHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNE 216
                L N+ ++  +  L   +L+S  N + E+I+++F  PW + +H  RR+   + L +
Sbjct: 88  EKNKALDNVKLMPQEIALIDTILDS--NDKIERIYINFCNPWPKDRHKKRRLTHTRQLTK 145

Query: 217 ALRVLKPRGFLELRTDDSLYFEDSLKLALKNFQCEIEI 254
               L   G +  +TDD   FE+SL+      +C  EI
Sbjct: 146 YRDFLVDGGEIHFKTDDDELFEESLEYFK---ECNFEI 180
>ref|NP_302680.1| (NC_002677) conserved hypothetical protein [Mycobacterium leprae]
 sp|Q9CCZ9|MT04_MYCLE Hypothetical methyltransferase ML2622
 emb|CAC32154.1| (AL583926) conserved hypothetical protein [Mycobacterium leprae]
          Length = 230

 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 34/125 (27%), Positives = 60/125 (47%), Gaps = 3/125 (2%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           +++E+G GSG   + +A++ P    + +E++   +AQ L  I+   + N+ ++ G+   V
Sbjct: 58  VVLEVGCGSGTATLAMAQHEPDIDVIAVEVYRRGLAQLLCAIDRDQVHNIRMIHGNALYV 117

Query: 181 LESMPNHR-CEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYF 237
           L+ +   R    + V FP PW + +H  RR L    +      L P G L   TD   Y 
Sbjct: 118 LQYLIAPRSLTGVRVFFPDPWPKVRHHKRRFLQPATVELIADRLLPGGVLHTATDHPDYA 177

Query: 238 EDSLK 242
           +   K
Sbjct: 178 KQIAK 182
>emb|CAB08804.1| (Z95398) unknown [Mycobacterium leprae]
          Length = 279

 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 34/125 (27%), Positives = 60/125 (47%), Gaps = 3/125 (2%)

Query: 121 ILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLV 180
           +++E+G GSG   + +A++ P    + +E++   +AQ L  I+   + N+ ++ G+   V
Sbjct: 107 VVLEVGCGSGTATLAMAQHEPDIDVIAVEVYRRGLAQLLCAIDRDQVHNIRMIHGNALYV 166

Query: 181 LESMPNHR-CEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTDDSLYF 237
           L+ +   R    + V FP PW + +H  RR L    +      L P G L   TD   Y 
Sbjct: 167 LQYLIAPRSLTGVRVFFPDPWPKVRHHKRRFLQPATVELIADRLLPGGVLHTATDHPDYA 226

Query: 238 EDSLK 242
           +   K
Sbjct: 227 KQIAK 231
>ref|NP_586458.1| (NC_003237) similarity to HYPOTHETICAL METHYLTRANSFERASE-LIKE
           PROTEIN YGGH_ECOLI [Encephalitozoon cuniculi]
 emb|CAD26062.1| (AL590450) similarity to HYPOTHETICAL METHYLTRANSFERASE-LIKE
           PROTEIN YGGH_ECOLI [Encephalitozoon cuniculi]
          Length = 243

 Score = 50.4 bits (119), Expect = 3e-05
 Identities = 33/139 (23%), Positives = 68/139 (48%), Gaps = 3/139 (2%)

Query: 110 FEDFIQKNQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKN 169
           +  + + N+ P  ++IG G G+ L+++A+ NP  + LG+EI          +IE   + N
Sbjct: 37  WSSYFRMNRRPDFVDIGCGYGKFLMKVAEKNPEHSILGLEIRDKVCEYVKARIEAAGIPN 96

Query: 170 LHILQGDGRLVLESM-PNHRCEKIFVHFPVPWNEKKHR--RVLSEKFLNEALRVLKPRGF 226
             +++ +  + L ++    +  KIF+ FP P  +K+ +  R++  + +     +L   G 
Sbjct: 97  AGVMRTNALIFLPNIFSRGQLTKIFILFPDPHFKKRKQKGRIVCRQMMEMYEYLLADGGK 156

Query: 227 LELRTDDSLYFEDSLKLAL 245
           L + TD    F   ++  L
Sbjct: 157 LYISTDVKELFNCMMEAVL 175
>ref|NP_633973.1| (NC_003901) methyltransferase [Methanosarcina mazei Goe1]
 gb|AAM31645.1| (AE013432) methyltransferase [Methanosarcina mazei Goe1]
          Length = 266

 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 40/138 (28%), Positives = 65/138 (46%), Gaps = 14/138 (10%)

Query: 122 LIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGRLVL 181
           ++E G G G   + LAKNNP      I+I   S+ +A +  E   +KN+  LQ +    +
Sbjct: 39  VLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQAN----I 94

Query: 182 ESMP--NHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDD--SLYF 237
            S+P  +   + IFV F +   +        E+ L    +VLKP G + +   D  S YF
Sbjct: 95  FSLPFEDSSFDHIFVCFVLEHLQS------PEEALKSLKKVLKPGGTITVIEGDHGSCYF 148

Query: 238 EDSLKLALKNFQCEIEIK 255
               K A++ + C I ++
Sbjct: 149 HPEGKKAIEAWNCLIRVQ 166
>ref|NP_521916.1| (NC_003296) HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
 emb|CAD17506.1| (AL646078) HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
          Length = 246

 Score = 45.1 bits (105), Expect = 0.001
 Identities = 38/141 (26%), Positives = 64/141 (44%), Gaps = 11/141 (7%)

Query: 119 APILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELLDLKNLHILQGDGR 178
           AP++ ++G G G     L      +  +GI+ H PS+A A KQ        + +L GD  
Sbjct: 55  APVIADVGCGQGISFRLLESAFAPQRMIGIDFHRPSLA-AAKQAAAALATPVDLLHGDCA 113

Query: 179 LVLESMPNHRCEKIFVHFPVPWNEKKHRRVLSEKFLNEALRVLKPRGFLELRTDDSLYFE 238
            +   +P+   + +F H      +  H  V  ++ L E  RVLKP G L       +Y +
Sbjct: 114 AL--PLPDASVDMVFCH------QTFHHLVEQDRALAEFHRVLKPGGLLLFAESTEVYIK 165

Query: 239 DSLKLALKNFQCEIEIKKNAQ 259
             +   L  F+  + ++K+AQ
Sbjct: 166 SWVIRLL--FRHPMHVQKSAQ 184
>gb|EAA13331.1| (AAAB01008968) ebiP3460 [Anopheles gambiae str. PEST]
          Length = 227

 Score = 45.1 bits (105), Expect = 0.001
 Identities = 35/128 (27%), Positives = 65/128 (50%), Gaps = 15/128 (11%)

Query: 117 NQAPILIEIGFGSGRHLIELAKNNPTKTCLGIEI------HTPSIAQALKQIELLDLKNL 170
           N+  +  +IG G G  L+ L +  P K  +G+EI      +     +AL+Q      +N+
Sbjct: 43  NRQVVFADIGCGYGGFLVTLGETFPDKLAIGMEIRVKVSDYVMDRIKALRQRHKGKYENI 102

Query: 171 HILQGDGRLVLESMPN----HRCEKIFVHFPVP-WNEKKHR-RVLSEKFLNEALRVLKPR 224
             ++ +    ++ +PN    H+ EK+F  +P P + + KH+ R+++   L+E   VL+P 
Sbjct: 103 ACIRTN---AMKYLPNYFRKHQLEKLFFLYPDPHFKKAKHKWRIINPTLLSEYAYVLRPG 159

Query: 225 GFLELRTD 232
           G +   TD
Sbjct: 160 GKIYTVTD 167
  Database: /home/scwang/download_20020708_db/nr
    Posted date:  Aug 7, 2002 12:55 PM
  Number of letters in database: 324,149,939
  Number of sequences in database:  1,026,957
  
Lambda     K      H
   0.322    0.140    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 247,725,759
Number of Sequences: 1026957
Number of extensions: 10387650
Number of successful extensions: 24126
Number of sequences better than 1.0e-02: 73
Number of HSP's better than  0.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 23986
Number of HSP's gapped (non-prelim): 79
length of query: 393
length of database: 324,149,939
effective HSP length: 123
effective length of query: 270
effective length of database: 197,834,228
effective search space: 53415241560
effective search space used: 53415241560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 98 (42.4 bits)