BLASTP 2.2.1 [Apr-13-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15645432|ref|NP_207606.1| conserved hypothetical
protein [Helicobacter pylori 26695]
(205 letters)
Database: /home/scwang/download_20020708_db/nr
1,026,957 sequences; 324,149,939 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_207606.1| (NC_000915) conserved hypothetical protein... 433 e-121
ref|NP_223467.1| (NC_000921) putative [Helicobacter pylori ... 424 e-118
ref|NP_281970.1| (NC_002163) putative hydrolase [Campylobac... 169 2e-41
ref|NP_600862.1| (NC_003450) COG0491:Zn-dependent hydrolase... 101 6e-21
ref|NP_348889.1| (NC_003030) Predicted Zn-dependent hydrola... 94 7e-19
ref|NP_562852.1| (NC_003366) conserved hypothetical protein... 91 1e-17
ref|NP_214462.1| (NC_000918) hypothetical protein [Aquifex ... 89 4e-17
ref|NP_301432.1| (NC_002677) putative hydrolase [Mycobacter... 88 7e-17
ref|NP_337157.1| (NC_002755) metallo-beta-lactamase superfa... 87 9e-17
ref|NP_217097.1| (NC_000962) hypothetical protein Rv2581c [... 87 9e-17
ref|NP_559365.1| (NC_003364) conserved protein (possibly me... 87 2e-16
ref|NP_622823.1| (NC_003869) Zn-dependent hydrolases, inclu... 86 2e-16
ref|NP_266698.1| (NC_002662) HYPOTHETICAL PROTEIN [Lactococ... 85 6e-16
ref|NP_296277.1| (NC_001263) conserved hypothetical protein... 80 1e-14
ref|NP_275039.1| (NC_003112) glyoxalase II family protein [... 79 2e-14
ref|NP_283217.1| (NC_003116) putative hydrolase [Neisseria ... 79 3e-14
ref|NP_415447.1| (NC_000913) orf, hypothetical protein [Esc... 79 4e-14
ref|NP_286802.1| (NC_002655) orf, hypothetical protein [Esc... 79 4e-14
ref|NP_465691.1| (NC_003210) similar to unknown proteins [L... 78 7e-14
ref|NP_658292.1| (NC_003995) lactamase_B, Metallo-beta-lact... 77 9e-14
ref|NP_625789.1| (NC_003888) possible hydrolase [Streptomyc... 77 1e-13
ref|NP_419999.1| (NC_002696) glyoxalase II family protein [... 76 2e-13
ref|NP_344443.1| (NC_002754) Conserved hypothetical protein... 76 3e-13
ref|NP_521387.1| (NC_003295) CONSERVED HYPOTHETICAL PROTEIN... 75 4e-13
ref|NP_378011.1| (NC_003106) 199aa long conserved hypotheti... 75 4e-13
ref|NP_405002.1| (NC_003143) metallo-beta-lactamase superfa... 75 5e-13
ref|NP_455483.1| (NC_003198) conserved hypothetical protein... 75 6e-13
ref|NP_459972.1| (NC_003197) putative Metallo-beta-lactamas... 74 8e-13
ref|NP_243686.1| (NC_002570) BH2820~unknown conserved prote... 73 2e-12
ref|NP_147830.1| (NC_000854) hypothetical protein [Aeropyru... 73 2e-12
ref|NP_230915.1| (NC_002505) glyoxylase II family protein [... 71 9e-12
ref|NP_599572.1| (NC_003450) COG0491:Zn-dependent hydrolase... 70 1e-11
ref|NP_439805.1| (NC_000907) conserved hypothetical protein... 69 3e-11
ref|NP_245209.1| (NC_002663) unknown [Pasteurella multocida... 69 3e-11
gb|EAA02936.1| (AAAB01007382) ebiP1693 [Anopheles gambiae s... 69 4e-11
ref|NP_604059.1| (NC_003454) Hydroxyacylglutathione hydrola... 69 4e-11
dbj|BAB97713.1| (AP005274) Zn-dependent hydrolases, includi... 69 4e-11
ref|NP_302290.1| (NC_002677) putative glyoxylase II [Mycoba... 67 2e-10
ref|NP_646314.1| (NC_003923) conserved hypothetical protein... 66 3e-10
ref|NP_372069.1| (NC_002758) conserved hypothetical protein... 66 3e-10
ref|NP_471602.1| (NC_003212) similar to unknown proteins [L... 65 6e-10
ref|NP_069409.1| (NC_000917) conserved hypothetical protein... 63 2e-09
ref|NP_614917.1| (NC_003551) Zn-dependent hydrolase [Methan... 62 4e-09
ref|NP_359083.1| (NC_003098) Conserved hypothetical protein... 62 5e-09
ref|NP_606880.1| (NC_003485) conserved hypothetical protein... 61 7e-09
ref|NP_386438.1| (NC_003047) CONSERVED HYPOTHETICAL PROTEIN... 61 7e-09
ref|NP_215148.1| (NC_000962) hypothetical protein Rv0634c [... 61 7e-09
ref|NP_390359.1| (NC_000964) similar to hypothetical protei... 61 9e-09
ref|NP_346086.1| (NC_003028) metallo-beta-lactamase superfa... 61 9e-09
ref|NP_625044.1| (NC_003888) putative hydrolase [Streptomyc... 60 2e-08
ref|NP_143108.1| (NC_000961) hypothetical protein [Pyrococc... 60 2e-08
dbj|BAA34381.1| (AB019513) very similar to Mycobacterium tu... 60 2e-08
ref|NP_268890.1| (NC_002737) conserved hypothetical protein... 58 6e-08
ref|NP_216153.1| (NC_000962) hypothetical protein Rv1637c [... 57 1e-07
ref|NP_126736.1| (NC_000868) HYDROXYACYLGLUTATHIONE HYDROLA... 57 1e-07
ref|NP_336789.1| (NC_002755) metallo-beta-lactamase superfa... 57 1e-07
ref|NP_579030.1| (NC_003413) hypothetical protein [Pyrococc... 57 1e-07
ref|NP_216776.1| (NC_000962) hypothetical protein Rv2260 [M... 57 1e-07
ref|NP_247883.1| (NC_000909) conserved hypothetical protein... 55 4e-07
ref|NP_389590.1| (NC_000964) pksB [Bacillus subtilis] >gi|7... 54 8e-07
ref|NP_539413.1| (NC_003317) HYDROXYACYLGLUTATHIONE HYDROLA... 54 1e-06
ref|NP_355161.1| (NC_003062) AGR_C_4004p [Agrobacterium tum... 54 1e-06
gb|EAA09645.1| (AAAB01008904) ebiP940 [Anopheles gambiae st... 54 1e-06
ref|NP_343464.1| (NC_002754) Conserved hypothetical protein... 53 2e-06
ref|NP_577767.1| (NC_003413) glyoxalase II family member [P... 52 3e-06
ref|NP_301989.1| (NC_002677) conserved hypothetical protein... 52 5e-06
ref|NP_103950.1| (NC_002678) probable hydrolase [Mesorhizob... 51 7e-06
ref|NP_142111.1| (NC_000961) hypothetical protein [Pyrococc... 51 7e-06
ref|NP_657766.1| (NC_003995) UPF0036, Uncharacterized prote... 50 2e-05
gb|AAF58646.2| (AE003826) CG30022-PA [Drosophila melanogaster] 49 3e-05
gb|AAH04749.1|AAH04749 (BC004749) Similar to hydroxyacyl gl... 49 3e-05
ref|NP_616720.1| (NC_003552) metallo-beta-lactamase [Methan... 49 4e-05
ref|NP_231867.1| (NC_002505) hydroxyacylglutathione hydrola... 49 4e-05
ref|NP_111449.1| (NC_002689) Zn-dependent hydrolase [Thermo... 49 4e-05
ref|NP_045994.1| (NC_001869) ORF H0571 [Halobacterium sp. N... 49 5e-05
ref|NP_377601.1| (NC_003106) 246aa long conserved hypotheti... 48 6e-05
ref|NP_600531.1| (NC_003450) COG0491:Zn-dependent hydrolase... 48 8e-05
ref|NP_203500.1| (NM_033349) hydroxyacyl glutathione hydrol... 47 1e-04
ref|NP_005317.1| (NM_005326) hydroxyacyl glutathione hydrol... 47 1e-04
ref|NP_633310.1| (NC_003901) hypothetical protein [Methanos... 47 1e-04
ref|NP_619473.1| (NC_003552) metallo-beta-lactamase [Methan... 47 1e-04
sp|Q28333|GLO2_CALJA Hydroxyacylglutathione hydrolase (Glyo... 47 1e-04
ref|NP_641426.1| (NC_003919) hydroxyacylglutathione hydrola... 47 1e-04
ref|NP_249523.1| (NC_002516) conserved hypothetical protein... 47 2e-04
ref|NP_626224.1| (NC_003888) putative hydrolase [Streptomyc... 47 2e-04
ref|NP_600593.1| (NC_003450) COG0491:Zn-dependent hydrolase... 46 2e-04
dbj|BAB83478.1| (AB063171) ORF2 [Staphylococcus hominis] 46 3e-04
dbj|BAA86645.1| (AB033763) hypothetical protein [Staphyloco... 46 3e-04
ref|NP_391950.1| (NC_000964) similar to hypothetical protei... 46 3e-04
ref|NP_660586.1| (NC_004061) probable hydroxyacylglutathion... 46 3e-04
ref|NP_370611.1| (NC_002758) conserved hypothetical protein... 45 4e-04
ref|NP_421662.1| (NC_002696) metallo-beta-lactamase family ... 45 4e-04
ref|NP_243264.1| (NC_002570) BH2398~unknown conserved prote... 45 4e-04
ref|NP_404693.1| (NC_003143) putative hydroxyacylglutathion... 45 5e-04
ref|NP_064383.1| (NM_019999) brain protein 17 [Mus musculus... 45 7e-04
ref|NP_644860.1| (NC_003923) hypothetical protein [Staphylo... 45 7e-04
ref|NP_376776.1| (NC_003106) 206aa long hypothetical protei... 45 7e-04
ref|NP_357719.1| (NC_003098) Conserved hypothetical protein... 44 9e-04
ref|NP_393565.1| (NC_002578) conserved hypothetical protein... 44 9e-04
ref|NP_344667.1| (NC_003028) metallo-beta-lactamase superfa... 44 9e-04
ref|NP_390528.1| (NC_000964) similar to hypothetical protei... 44 0.001
ref|NP_269869.1| (NC_002737) conserved hypothetical protein... 44 0.001
ref|NP_654720.1| (NC_003995) lactamase_B, Metallo-beta-lact... 43 0.002
ref|NP_299439.1| (NC_002488) hydroxyacylglutathione hydrola... 43 0.003
ref|NP_109968.1| (NC_000912) similar to single stranded RNA... 43 0.003
ref|NP_656979.1| (NC_003995) lactamase_B, Metallo-beta-lact... 43 0.003
ref|NP_125729.1| (NC_000868) hypothetical protein [Pyrococc... 42 0.003
ref|NP_071229.1| (NC_000917) conserved hypothetical protein... 42 0.003
ref|NP_148499.1| (NC_000854) hypothetical protein [Aeropyru... 42 0.003
gb|AAG51989.1|AC024260_27 (AC024260) glyoxalase II, putativ... 42 0.003
gb|AAB17995.1| (U74610) glyoxalase II [Arabidopsis thaliana] 42 0.003
ref|NP_564636.1| (NM_104236) glyoxalase II, putative [Arabi... 42 0.003
gb|AAF89153.1|AF189297_1 (AF189297) class B carbapenemase G... 42 0.003
ref|NP_103568.1| (NC_002678) hypothetical protein [Mesorhiz... 42 0.004
gb|AAH02937.1|AAH02937 (BC002937) Similar to hypothetical p... 42 0.004
ref|NP_294381.1| (NC_001263) conserved hypothetical protein... 42 0.004
ref|XP_087163.2| (XM_087163) KIAA1184 protein [Homo sapiens] 42 0.004
dbj|BAA86498.1| (AB033010) KIAA1184 protein [Homo sapiens] 42 0.004
ref|NP_636363.1| (NC_003902) hydroxyacylglutathione hydrola... 42 0.004
gb|EAA02540.1| (AAAB01005245) ebiP92 [Anopheles gambiae str... 42 0.006
gb|AAH08250.1|AAH08250 (BC008250) Similar to RIKEN cDNA 061... 42 0.006
gb|AAF89147.1|AF189291_1 (AF189291) class B carbapenemase G... 42 0.006
ref|NP_588246.1| (NC_003421) putative hydroxyacylglutathion... 42 0.006
ref|NP_343676.1| (NC_002754) Conserved hypothetical protein... 42 0.006
gb|AAG09063.1|AC018758_3 (AC018758) protein expressed in th... 42 0.006
ref|NP_055112.1| (NM_014297) protein expressed in thyroid [... 42 0.006
ref|NP_599542.1| (NC_003450) COG0491:Zn-dependent hydrolase... 42 0.006
gb|AAF89148.1|AF189292_1 (AF189292) class B carbapenemase G... 42 0.006
ref|NP_348031.1| (NC_003030) Zn-dependent hydrolase, glyoxy... 41 0.007
ref|NP_349408.1| (NC_003030) Predicted Zn-dependent hydrola... 41 0.007
gb|AAF89152.1|AF189296_1 (AF189296) class B carbapenemase G... 41 0.010
gb|AAF04458.1|AF090141_1 (AF090141) GOB-1 carbapenemase [Ch... 41 0.010
gb|AAF89146.1|AF189290_1 (AF189290) class B carbapenemase G... 41 0.010
gb|AAF89149.1|AF189293_1 (AF189293) class B carbapenemase G... 41 0.010
ref|NP_496556.1| (NM_064155) Metallo-beta-lactamase superfa... 41 0.010
gb|AAF89150.1|AF189294_1 (AF189294) class B carbapenemase G... 41 0.010
gb|AAG10453.1|AF279106_15 (AF279106) predicted metallobeta ... 41 0.010
>ref|NP_207606.1| (NC_000915) conserved hypothetical protein [Helicobacter pylori
26695]
pir||E64621 conserved hypothetical protein HP0813 - Helicobacter pylori
(strain 26695)
gb|AAD07862.1| (AE000593) conserved hypothetical protein [Helicobacter pylori
26695]
Length = 205
Score = 433 bits (1114), Expect = e-121
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD 60
MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD
Sbjct: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD 60
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYW 120
GAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYW
Sbjct: 61 GAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYW 120
Query: 121 HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI
Sbjct: 121 HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
Query: 181 YPGHGDKTSFFAEREHSKIWVSRMA 205
YPGHGDKTSFFAEREHSKIWVSRMA
Sbjct: 181 YPGHGDKTSFFAEREHSKIWVSRMA 205
>ref|NP_223467.1| (NC_000921) putative [Helicobacter pylori J99]
pir||G71891 hypothetical protein jhp0749 - Helicobacter pylori (strain J99)
gb|AAD06340.1| (AE001506) putative [Helicobacter pylori J99]
Length = 205
Score = 424 bits (1090), Expect = e-118
Identities = 200/205 (97%), Positives = 201/205 (97%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD 60
MEILRRECGAVEENAYIVKLSSG+DFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD
Sbjct: 1 MEILRRECGAVEENAYIVKLSSGVDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD 60
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYW 120
AQLSK LK TPIYAPKDDVFMLENDIFHLGMPVFSP FSVPCNKGCTTLEIANTTIKYW
Sbjct: 61 SAQLSKALKGTPIYAPKDDVFMLENDIFHLGMPVFSPTFSVPCNKGCTTLEIANTTIKYW 120
Query: 121 HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI
Sbjct: 121 HFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
Query: 181 YPGHGDKTSFFAEREHSKIWVSRMA 205
YPGHGDKTSFFAEREHSKIWVSRMA
Sbjct: 181 YPGHGDKTSFFAEREHSKIWVSRMA 205
>ref|NP_281970.1| (NC_002163) putative hydrolase [Campylobacter jejuni]
pir||A81353 probable hydrolase Cj0809c [imported] - Campylobacter jejuni
(strain NCTC 11168)
emb|CAB73074.1| (AL139076) putative hydrolase [Campylobacter jejuni]
Length = 198
Score = 169 bits (427), Expect = 2e-41
Identities = 90/203 (44%), Positives = 127/203 (62%), Gaps = 10/203 (4%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWD 60
M+I+++ CG E N YI+ G +FIIDPG + ++ ++ KNP AIL THGHYDH+WD
Sbjct: 1 MQIIKQACGVYETNCYILFTPKG-EFIIDPGTDALLFIKKHVKNPLAILNTHGHYDHIWD 59
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYW 120
A++ K N PIY K+D FML +D F+ G +F V L I K+
Sbjct: 60 NAKVKKEY-NIPIYIHKNDAFMLHDD-FNQGYDSSDADFLVDNE---DILNICGVDFKFH 114
Query: 121 HFPGHTPGCSIIEIEG--VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDI 178
PGHTPGC++IEI G ++FSGDF+FYRSIGR+DFPYS+ MK+SL + + + +D
Sbjct: 115 FLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFPYSDANLMKQSLEKV--MTYKEDF 172
Query: 179 EIYPGHGDKTSFFAEREHSKIWV 201
++ PGHG +T+ E+ H W+
Sbjct: 173 KLLPGHGQETTLKEEQVHLPSWL 195
>ref|NP_600862.1| (NC_003450) COG0491:Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum]
dbj|BAB99041.1| (AP005279) Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum ATCC 13032]
Length = 213
Score = 101 bits (251), Expect = 6e-21
Identities = 72/207 (34%), Positives = 100/207 (47%), Gaps = 16/207 (7%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSS----EWVLENAKNPKAILITHGHYD 56
MEIL G + N Y+V+ + + IIDPG + E++ N + I++THGH D
Sbjct: 1 MEILGFAAGPYKTNCYVVRGENEVA-IIDPGMHAHDDLVEYITTNNLSVDKIVLTHGHID 59
Query: 57 HVWDGAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGMPVFSPNFSVPCNKGCT----- 108
H D ++K N P+Y DD F LE M + N P +
Sbjct: 60 HTRDAGVVAKRF-NAPVYIHPDDAFFLEVYKGSGTKTAMLFDADNMVSPDPESLRDLVDG 118
Query: 109 -TLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLL 167
T+ +A H PGH+PGC++I + FSGD +F SIGR DF +S+ M ES L
Sbjct: 119 ETITLAGEEFTLKHAPGHSPGCTLIVGKEYCFSGDVLFKGSIGRTDFEWSDADAMNES-L 177
Query: 168 RFQNLDFPKDIEIYPGHGDKTSFFAER 194
R L ++I PGHG T+ AER
Sbjct: 178 RTAVLPLDDALQILPGHGPTTTMRAER 204
>ref|NP_348889.1| (NC_003030) Predicted Zn-dependent hydrolase of
metallo-beta-lactamase superfamily [Clostridium
acetobutylicum]
gb|AAK80229.1|AE007728_8 (AE007728) Predicted Zn-dependent hydrolase of
metallo-beta-lactamase superfamily [Clostridium
acetobutylicum]
Length = 199
Score = 94.4 bits (233), Expect = 7e-19
Identities = 70/202 (34%), Positives = 103/202 (50%), Gaps = 11/202 (5%)
Query: 1 MEILRRECGAVEENAYI-VKLSSGIDFIIDPGFSSSEWVLENAK----NPKAILITHGHY 55
M+I + GA N YI V S +IDPG + + +LE K N K +L+THGH
Sbjct: 1 MKISVIQAGAYMTNCYILVDEKSNESVVIDPG-DAPQAILEAFKDTETNLKFVLLTHGHA 59
Query: 56 DHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANT 115
DH A+L K N +Y KDD ++EN + G S N + + G L+
Sbjct: 60 DHTAAVAELKKEY-NVDVYMNKDDCKLIENGEYMFGDK--SENATKYVDDG-DELQFGEL 115
Query: 116 TIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFP 175
IK PGHTPG ++ +FSGD +F SIGR DFP + + S ++ + +
Sbjct: 116 KIKCIKTPGHTPGGMCYLVDNYLFSGDTLFNSSIGRTDFPGGDFSTLINS-IKSKLMKLD 174
Query: 176 KDIEIYPGHGDKTSFFAEREHS 197
++I +YPGHG+ T+ E+ H+
Sbjct: 175 ENIVVYPGHGEGTTIGYEKIHN 196
>ref|NP_562852.1| (NC_003366) conserved hypothetical protein [Clostridium
perfringens]
dbj|BAB81642.1| (AP003192) conserved hypothetical protein [Clostridium perfringens]
Length = 206
Score = 90.5 bits (223), Expect = 1e-17
Identities = 67/193 (34%), Positives = 95/193 (48%), Gaps = 9/193 (4%)
Query: 9 GAVEENAYIVKLSSGIDFI-IDPGFSSS--EWVLENAK-NPKAILITHGHYDHVWDGAQL 64
G + N Y+V D I +DPG +S E V+E+ PK IL+THGH+DHV +L
Sbjct: 9 GMYQANCYVVIDEETKDCIMVDPGEEASRIENVIESLDAKPKMILLTHGHFDHVGAVQKL 68
Query: 65 SKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPG 124
++ K P Y K D M+E ++ G P G T N IK PG
Sbjct: 69 AEKYK-IPFYIDKKDEDMIERNVDVFGK---LPKADGYLKDGDTLKFSDNYEIKCLETPG 124
Query: 125 HTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
HTPG I+ +F+GD +F SIGR DF N + +S + + + DI +YPGH
Sbjct: 125 HTPGGLCFLIDNCLFTGDTLFRESIGRSDFEGGNHATLLKS-INDKLVPLGDDIVVYPGH 183
Query: 185 GDKTSFFAEREHS 197
G ++ ER+ +
Sbjct: 184 GPSSTIKHERQRN 196
>ref|NP_214462.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
sp|O67893|YL35_AQUAE Hypothetical protein AQ_2135
pir||A70483 conserved hypothetical protein aq_2135 - Aquifex aeolicus
gb|AAC07862.1| (AE000774) hypothetical protein [Aquifex aeolicus]
Length = 211
Score = 88.6 bits (218), Expect = 4e-17
Identities = 63/182 (34%), Positives = 97/182 (52%), Gaps = 14/182 (7%)
Query: 22 SGIDFIIDPGFSSSEWVLENAKNPKA--ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDD 79
SG IIDPG + +E +LE K+ K I+ THGH DHV +L +L + P Y D
Sbjct: 23 SGEAIIIDPG-AEAEKILEAVKDFKVVGIVATHGHIDHVGQVGKLKELF-DVPFYMNPLD 80
Query: 80 VFMLENDIF-----HLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSII 132
F++ ++I+ ++G V P V ++G + + + K H PGHTPG C
Sbjct: 81 KFLINDEIWSGFASYIGA-VPCPEPDVEISEG-DVIRVGDVEFKVLHTPGHTPGLCCLYE 138
Query: 133 EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFA 192
E V+ +GD +F S+GR+D P N ++K+S+ R + P+D + GH D+T+
Sbjct: 139 EKRRVLIAGDLLFKGSVGRWDLPGGNLVELKKSVKRVLT-ELPQDTLVICGHYDETTIGQ 197
Query: 193 ER 194
ER
Sbjct: 198 ER 199
>ref|NP_301432.1| (NC_002677) putative hydrolase [Mycobacterium leprae]
sp|Q49649|YP81_MYCLE Hypothetical protein ML0493
pir||S72738 B1177_C3_247 protein - Mycobacterium leprae
gb|AAA17102.1| (U00011) B1177_C3_247 [Mycobacterium leprae]
emb|CAA19086.1| (AL023591) hypothetical protein MLCB1259.11 [Mycobacterium leprae]
emb|CAC30001.1| (AL583918) putative hydrolase [Mycobacterium leprae]
Length = 218
Score = 87.8 bits (216), Expect = 7e-17
Identities = 62/203 (30%), Positives = 99/203 (48%), Gaps = 19/203 (9%)
Query: 9 GAVEENAYIVKLSSGID-FIIDPGFSSS----EWVLENAKNPKAILITHGHYDHVWDGAQ 63
G ++ N Y++ +G D I+DPG + + EN P A+L+THGH DH+W +
Sbjct: 9 GMLQCNCYVLADRAGTDAVIVDPGQRAMGPLRRILDENRLTPSAVLLTHGHIDHMWSAQK 68
Query: 64 LSKLLKNTPIYAPKDDVFMLENDIFHLGMPVF---------SPNFSVPCNKGCTTLEIAN 114
+S P Y +D FML + +F G V P V ++ L++ +
Sbjct: 69 VSDTY-GCPTYIHPEDRFMLTDPLFGFGPRVAQVVTGAFFREPKQVVELDRDGDKLDLGS 127
Query: 115 TTIKYWHFPGHTPG--CSIIEIE-GVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
T+ H PGHT G C + + V+ +GD +F R+IGR D + +D+ S++ +
Sbjct: 128 VTVNVDHTPGHTRGSVCFWVAADTDVVLTGDTLFERTIGRTDLFGGSGRDLYRSIVE-KL 186
Query: 172 LDFPKDIEIYPGHGDKTSFFAER 194
L + PGHG+ T+ AER
Sbjct: 187 LVLDDKTVVLPGHGNSTTIGAER 209
>ref|NP_337157.1| (NC_002755) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
gb|AAK46971.1| (AE007099) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
Length = 246
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/207 (28%), Positives = 98/207 (46%), Gaps = 23/207 (11%)
Query: 9 GAVEENAYIVKLSSGID-FIIDPG---FSSSEWVLE-NAKNPKAILITHGHYDHVWDGAQ 63
G + N Y++ G D I+DPG + +L+ N P A+L+THGH DH+W +
Sbjct: 31 GLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQK 90
Query: 64 LSKLLKNTPIYAPKDDVFMLENDIFHLGMPVF---------SPNFSVPCNKGCTTLEIAN 114
+S P Y D FML + I+ LG + P V ++ +++
Sbjct: 91 VSDTF-GCPTYVHPADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGG 149
Query: 115 TTIKYWHFPGHTPGCSIIEI-------EGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLL 167
++ H PGHT G + + + ++F+GD +F R+IGR D + +D+ S++
Sbjct: 150 ISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIV 209
Query: 168 RFQNLDFPKDIEIYPGHGDKTSFFAER 194
+ L + PGHG+ T+ AER
Sbjct: 210 D-KLLVLDDSTVVLPGHGNSTTIGAER 235
>ref|NP_217097.1| (NC_000962) hypothetical protein Rv2581c [Mycobacterium
tuberculosis H37Rv]
sp|Q50640|YP81_MYCTU Hypothetical protein Rv2581c
pir||D70725 hypothetical protein Rv2581c - Mycobacterium tuberculosis (strain
H37RV)
emb|CAB01262.1| (Z77724) hypothetical protein Rv2581c [Mycobacterium tuberculosis
H37Rv]
Length = 224
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/207 (28%), Positives = 98/207 (46%), Gaps = 23/207 (11%)
Query: 9 GAVEENAYIVKLSSGID-FIIDPG---FSSSEWVLE-NAKNPKAILITHGHYDHVWDGAQ 63
G + N Y++ G D I+DPG + +L+ N P A+L+THGH DH+W +
Sbjct: 9 GLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQK 68
Query: 64 LSKLLKNTPIYAPKDDVFMLENDIFHLGMPVF---------SPNFSVPCNKGCTTLEIAN 114
+S P Y D FML + I+ LG + P V ++ +++
Sbjct: 69 VSDTF-GCPTYVHPADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGG 127
Query: 115 TTIKYWHFPGHTPGCSIIEI-------EGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLL 167
++ H PGHT G + + + ++F+GD +F R+IGR D + +D+ S++
Sbjct: 128 ISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIV 187
Query: 168 RFQNLDFPKDIEIYPGHGDKTSFFAER 194
+ L + PGHG+ T+ AER
Sbjct: 188 D-KLLVLDDSTVVLPGHGNSTTIGAER 213
>ref|NP_559365.1| (NC_003364) conserved protein (possibly metallo-beta-lactamase
superfamily) [Pyrobaculum aerophilum]
gb|AAL63547.1| (AE009826) conserved protein (possibly metallo-beta-lactamase
superfamily) [Pyrobaculum aerophilum]
Length = 207
Score = 86.7 bits (213), Expect = 2e-16
Identities = 64/197 (32%), Positives = 95/197 (47%), Gaps = 15/197 (7%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE-NAKNPKAILITHGHYDHVW 59
M + R G + N+YIV +IDPG + + K+ A++ TH H+DHV
Sbjct: 1 MNVERVIVGPLATNSYIVCEREEC-VVIDPGAEGDRIMRQLGRKSLVAVVATHLHFDHVG 59
Query: 60 DGAQLSKLLKNTPIYAPKDD--VFMLENDIFH-LGMPVFSPNFSVPCNKGCTTLEIANTT 116
A+L + YA DD ++ N I G V P P G +
Sbjct: 60 AVARLVEAT-GAEFYAHSDDWRIYKSLNQIAEDWGFAV--PELPTPRGLGSRVWRL---- 112
Query: 117 IKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPK 176
+ H PGHTPG + +G +F+GD +FYRS+GR D PY + + + +S+ R L P
Sbjct: 113 -EVLHTPGHTPGSISLVGDGFVFTGDALFYRSVGRTDLPYGDWEALVQSVCRLYGL--PP 169
Query: 177 DIEIYPGHGDKTSFFAE 193
++YPGHG +T+ AE
Sbjct: 170 SFQVYPGHGPETTIGAE 186
>ref|NP_622823.1| (NC_003869) Zn-dependent hydrolases, including glyoxylases
[Thermoanaerobacter tengcongensis]
gb|AAM24427.1| (AE013082) Zn-dependent hydrolases, including glyoxylases
[Thermoanaerobacter tengcongensis]
Length = 214
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/203 (32%), Positives = 96/203 (46%), Gaps = 13/203 (6%)
Query: 1 MEILRRECGAVEENAYIV---KLSSGIDFIIDPGFSSSE---WVLENAKNPKAILITHGH 54
ME+ R G N Y+V GI IIDPG E ++ EN K IL+THGH
Sbjct: 6 MEVKRYVVGPYGANLYVVWDRDTREGI--IIDPGEVYDEIKNYIKENGIKVKHILLTHGH 63
Query: 55 YDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCN---KGCTTLE 111
+DH+ G + + + ++D ML + +L VF P + K L
Sbjct: 64 FDHI-GGVEEIRAFTGGKVAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLG 122
Query: 112 IANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
N ++ PGHT G +I V F+GD +F SIGR+DFP N + + S ++ +
Sbjct: 123 FGNYYVEVISTPGHTKGSVCFKIGDVYFTGDTLFRGSIGRHDFPGGNFETLMAS-IKERL 181
Query: 172 LDFPKDIEIYPGHGDKTSFFAER 194
L + IYPGHGD ++ E+
Sbjct: 182 LTLKDETVIYPGHGDFSTIGREK 204
>ref|NP_266698.1| (NC_002662) HYPOTHETICAL PROTEIN [Lactococcus lactis subsp. lactis]
gb|AAK04640.1|AE006288_3 (AE006288) HYPOTHETICAL PROTEIN [Lactococcus lactis subsp. lactis]
Length = 210
Score = 84.7 bits (208), Expect = 6e-16
Identities = 63/200 (31%), Positives = 101/200 (50%), Gaps = 19/200 (9%)
Query: 12 EENAYIVKLSSGIDFIIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLSKLL 68
+EN Y++ S+ IIDPG SS E + K AIL+TH H+DH+ +L K
Sbjct: 12 QENTYLLSNSTS-HLIIDPGSDSSALLERLKITDKTISAILLTHAHFDHIIGLNELRKHF 70
Query: 69 KNTPIYAPKDDVFMLEN-----DIFHLGMPVFSP--NFSVPCNKGCTTLEIANTTIKYWH 121
+ PIY + ++N F LG V P ++ N+ +I +
Sbjct: 71 PDVPIYLHSAEKEWMKNPKLNASFFFLGTAVTGPEADYFYEINQ---FYDIDAFKFQVLE 127
Query: 122 FPGHT-PGCSII---EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKD 177
PGH+ G S++ E E +FSGD +F +IGR+D P N+ + +S +R Q ++
Sbjct: 128 TPGHSIGGVSLLFKLENESFVFSGDALFKNAIGRWDLPTGNQAQLLKS-IREQLFTLDEN 186
Query: 178 IEIYPGHGDKTSFFAEREHS 197
+++PGHG KTS E++++
Sbjct: 187 TQVFPGHGPKTSIGTEKQNN 206
>ref|NP_296277.1| (NC_001263) conserved hypothetical protein [Deinococcus
radiodurans]
pir||C75258 conserved hypothetical protein - Deinococcus radiodurans (strain
R1)
gb|AAF12098.1|AE002085_1 (AE002085) conserved hypothetical protein [Deinococcus radiodurans]
Length = 215
Score = 80.1 bits (196), Expect = 1e-14
Identities = 57/197 (28%), Positives = 89/197 (44%), Gaps = 18/197 (9%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLS 65
G ++ENA +V S F+IDPG ++ + V + +AIL+TH H+DH+ +
Sbjct: 20 GPLQENALLVAGSDNQGFLIDPGDEAARILDLVRAAGVDVQAILLTHAHFDHIGAVQPVR 79
Query: 66 KLLKNTPIYAPKDDVFMLENDIFHLG--------MPVFSPNFSVPCNKGCTTLEIANTTI 117
+ L P++ DD+ +HLG +P P T + T+
Sbjct: 80 EAL-GVPVHLHADDLAT-----YHLGAASAGRWNLPFVQPADPDQQIAQDQTFTAGDLTL 133
Query: 118 KYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKD 177
PGH PG + +G + +GD +F IGR D P N + + R + L P D
Sbjct: 134 TARELPGHAPGHVVFVGDGFVIAGDTLFAGGIGRTDLPGGNHPQLIAGIER-ELLSLPDD 192
Query: 178 IEIYPGHGDKTSFFAER 194
+YPGHG T+ E+
Sbjct: 193 TYVYPGHGGFTTIGREK 209
>ref|NP_275039.1| (NC_003112) glyoxalase II family protein [Neisseria meningitidis
MC58]
pir||B81011 glyoxalase II family protein NMB2049 [imported] - Neisseria
meningitidis (group B strain MD58)
gb|AAF42369.1| (AE002555) glyoxalase II family protein [Neisseria meningitidis
MC58]
Length = 210
Score = 79.3 bits (194), Expect = 2e-14
Identities = 54/163 (33%), Positives = 82/163 (50%), Gaps = 20/163 (12%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPK-DDVFMLEN---DIFHLGMPV---FSPNF 99
AI +THGH DH ++ K K P+ P DD F+L++ G PV F+PN
Sbjct: 53 AIWLTHGHLDHAGGVVEMLKTHK-VPVLGPHPDDEFLLQSLPQTTAQYGFPVSPAFAPNR 111
Query: 100 SVPCNKGCTTLEIANTTIKYWHFPGHTPG-----CSIIEIEGVIFSGDFIFYRSIGRYDF 154
+ + TL + + H PGHTPG C+ E+ + +GD +FY +IGR DF
Sbjct: 112 WLEEGE---TLTVGRYAFQVLHIPGHTPGHIVFYCAEAEL---LIAGDVLFYETIGRTDF 165
Query: 155 PYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHS 197
P N D+ + +R + P+ +++ GHG TS E+ H+
Sbjct: 166 PRGNHADLINN-IRNKLFTLPETVQVVAGHGRMTSIGHEKRHN 207
>ref|NP_283217.1| (NC_003116) putative hydrolase [Neisseria meningitidis Z2491]
pir||A81955 probable hydrolase NMA0387 [imported] - Neisseria meningitidis
(group A strain Z2491)
emb|CAB83688.1| (AL162753) putative hydrolase [Neisseria meningitidis Z2491]
Length = 210
Score = 79.0 bits (193), Expect = 3e-14
Identities = 54/163 (33%), Positives = 82/163 (50%), Gaps = 20/163 (12%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPK-DDVFMLEN---DIFHLGMPV---FSPNF 99
AI +THGH DH ++ K K P+ P DD F+L++ G PV F+PN
Sbjct: 53 AIWLTHGHLDHAGGVVEMLKTHK-VPVLGPHPDDEFLLQSLPQTTAQYGFPVSPAFAPNR 111
Query: 100 SVPCNKGCTTLEIANTTIKYWHFPGHTPG-----CSIIEIEGVIFSGDFIFYRSIGRYDF 154
+ + TL + + H PGHTPG C+ E+ + +GD +FY +IGR DF
Sbjct: 112 WLEEGE---TLTVGRYAFQVLHIPGHTPGHIVFYCAEAEL---LIAGDVLFYETIGRTDF 165
Query: 155 PYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHS 197
P N D+ + +R + P+ +++ GHG TS E+ H+
Sbjct: 166 PRGNHADLINN-IRNKLFALPETVQVVAGHGRMTSIGHEKRHN 207
>ref|NP_415447.1| (NC_000913) orf, hypothetical protein [Escherichia coli K12]
sp|P75849|YCBL_ECOLI Hypothetical protein ycbL
pir||F64832 probable hydrolase (EC 3.-.-.-) ycbL - Escherichia coli
gb|AAC74013.1| (AE000195) orf, hypothetical protein [Escherichia coli K12]
dbj|BAA35673.1| (D90730) Hypothetical 23.2 kd protein in sodA-comGA intergenic
region. [Escherichia coli]
dbj|BAA35679.1| (D90731) Hypothetical 23.2 kd protein in sodA-comGA intergenic
region. [Escherichia coli]
Length = 215
Score = 78.6 bits (192), Expect = 4e-14
Identities = 58/187 (31%), Positives = 92/187 (49%), Gaps = 25/187 (13%)
Query: 27 IIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAP-KDDVFM 82
++DPG + + V ++ IL+THGH DHV A+L++ P++ P K+D F
Sbjct: 28 LVDPGGDAEKIKQEVDDSGLTLMQILLTHGHLDHVGAAAELAQHY-GVPVFGPEKEDEFW 86
Query: 83 LENDIFHLGMPVFSPNFSVP----------CNKGCTTLEIANTTIKYWHFPGHTPGCSII 132
L+ G+P S F + N+G T+ I N T++ H PGHTPG +
Sbjct: 87 LQ------GLPAQSRMFGLEECQPLTPDRWLNEG-DTISIGNVTLQVLHCPGHTPGHVVF 139
Query: 133 --EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSF 190
+ ++ SGD IF +GR DFP + + S ++ + L D+ PGHG ++
Sbjct: 140 FDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISS-IKDKLLPLGDDVIFIPGHGPLSTL 198
Query: 191 FAEREHS 197
ER H+
Sbjct: 199 GYERLHN 205
>ref|NP_286802.1| (NC_002655) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
ref|NP_309037.1| (NC_002695) hypothetical protein [Escherichia coli O157:H7]
gb|AAG55412.1|AE005282_7 (AE005282) orf, hypothetical protein [Escherichia coli O157:H7
EDL933]
dbj|BAB34433.1| (AP002553) hypothetical protein [Escherichia coli O157:H7]
Length = 215
Score = 78.6 bits (192), Expect = 4e-14
Identities = 58/187 (31%), Positives = 91/187 (48%), Gaps = 25/187 (13%)
Query: 27 IIDPGFSSSEWVLE---NAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAP-KDDVFM 82
++DPG + + E + IL+THGH DHV A+L++ P++ P K+D F
Sbjct: 28 LVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHY-GVPVFGPEKEDEFW 86
Query: 83 LENDIFHLGMPVFSPNFSVP----------CNKGCTTLEIANTTIKYWHFPGHTPGCSII 132
L+ G+P S F + N+G T+ I N T++ H PGHTPG +
Sbjct: 87 LQ------GLPAQSRMFGLEECQPLTPDRWLNEG-DTISIGNVTLQVLHCPGHTPGHVVF 139
Query: 133 --EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSF 190
+ ++ SGD IF +GR DFP + + S ++ + L D+ PGHG ++
Sbjct: 140 FDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISS-IKDKLLPLGDDVTFIPGHGPLSTL 198
Query: 191 FAEREHS 197
ER H+
Sbjct: 199 GYERLHN 205
>ref|NP_465691.1| (NC_003210) similar to unknown proteins [Listeria monocytogenes
EGD-e]
emb|CAD00245.1| (AL591982) similar to unknown proteins [Listeria monocytogenes]
Length = 205
Score = 77.8 bits (190), Expect = 7e-14
Identities = 60/200 (30%), Positives = 90/200 (45%), Gaps = 9/200 (4%)
Query: 2 EILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAK---NPKAILITHGHYDHV 58
+I R G ++EN YI+ + I+DPG +S+ E AK P A+L+TH HYDH+
Sbjct: 3 KIKRIMTGIIQENCYII-YQDNVALIVDPGDEASKIEAEIAKLEVKPVAVLLTHCHYDHI 61
Query: 59 WDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTL---EIANT 115
++ K N P+Y + L N +L + + TL I
Sbjct: 62 GALEEIRKTY-NIPVYVSPLEQEWLSNPELNLSAHIAGKAIIAQPAENEFTLGEYNIEGF 120
Query: 116 TIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFP 175
K PGH+ G + + GD +F SIGR D Y+ + DM + ++ Q P
Sbjct: 121 RFKVVPTPGHSIGSVSFIFDEFVVVGDALFKGSIGRTDL-YTGDFDMLINSIKTQLFVLP 179
Query: 176 KDIEIYPGHGDKTSFFAERE 195
D Y GHGD T+ E++
Sbjct: 180 DDFPAYSGHGDVTTIGHEKK 199
>ref|NP_658292.1| (NC_003995) lactamase_B, Metallo-beta-lactamase superfamily
[Bacillus anthracis A2012] [Bacillus anthracis str.
A2012]
Length = 208
Score = 77.4 bits (189), Expect = 9e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVL---ENAKNPKAILITHGHYDH 57
M+ ++ G ++ NAYI+K I DPG + V E P A+L+TH H+DH
Sbjct: 1 MKWIQMPLGPLQTNAYILKNDKNECVIFDPGHEGEKLVTYLQEEQLKPLAVLLTHAHFDH 60
Query: 58 VWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGC------TTLE 111
+ + + P+Y K++ ++ D G +F N S+ TL
Sbjct: 61 I-GAVDAXRDAFHIPVYVHKEEDWL--GDXXVNGSQIFMMNRSITAKPADHIIDAEGTLA 117
Query: 112 IANTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRF 169
I + + + PGH+PG + +FSGD +F SIGR D P + ++ S +
Sbjct: 118 IGSFNFEIFETPGHSPGSISYYCKEASAVFSGDVLFQMSIGRTDLPGGSFAELIGS-IEE 176
Query: 170 QNLDFPKDIEIYPGHGDKTSFFAEREHS 197
+ P + + GHG +TS E+E++
Sbjct: 177 KLFVLPDETAVLCGHGPETSIGFEKENN 204
>ref|NP_625789.1| (NC_003888) possible hydrolase [Streptomyces coelicolor A3(2)]
emb|CAB93389.1| (AL357523) possible hydrolase [Streptomyces coelicolor A3(2)]
Length = 235
Score = 77.0 bits (188), Expect = 1e-13
Identities = 68/207 (32%), Positives = 95/207 (45%), Gaps = 24/207 (11%)
Query: 9 GAVEENAYIVKLSSGID-FIIDPGFSSSEWVLENAKN----PKAILITHGHYDHVWDGAQ 63
GA N Y+V ++G + IIDPG ++ V E + P A+++THGH DHV
Sbjct: 9 GAWGTNCYLVAPAAGEECVIIDPGHQAAPGVEEAIRKHRLKPVAVVLTHGHIDHVASVVP 68
Query: 64 LSKLLKNTPIYAPKDDVFML---ENDIFH-LGMPVFS------PNFSVPCNKGCTTLEIA 113
+ + P + +D FM+ E I +GMP+ P+ G L +A
Sbjct: 69 VCGA-HDVPAWIHPEDRFMMSDPEKGIGRSIGMPLMGELTVGEPDDVKELTDGAR-LALA 126
Query: 114 NTTIKYWHFPGHTPGC------SIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLL 167
+ H PGHT G +I V+FSGD +F SIGR DFP + DM ESL
Sbjct: 127 GLELTVAHAPGHTKGSVTFGLPEAADIPPVMFSGDLLFAGSIGRTDFPGGSMDDMLESLA 186
Query: 168 RFQNLDFPKDIEIYPGHGDKTSFFAER 194
R L + GHG +T+ ER
Sbjct: 187 RV-CLPLDDSTVVLSGHGPQTTIGQER 212
>ref|NP_419999.1| (NC_002696) glyoxalase II family protein [Caulobacter crescentus
CB15]
gb|AAK23167.1| (AE005796) glyoxalase II family protein [Caulobacter crescentus
CB15]
Length = 273
Score = 76.3 bits (186), Expect = 2e-13
Identities = 58/177 (32%), Positives = 84/177 (46%), Gaps = 11/177 (6%)
Query: 27 IIDPGFSSSEW---VLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAP-KDDVFM 82
+IDPG + + + I ITHGH DH A+L K PI P KDD F
Sbjct: 69 VIDPGGEVDRLLKAIADKGLTLEKIWITHGHMDHAGGAAEL-KARTGVPIEGPHKDDQFW 127
Query: 83 LEN--DIFHL-GMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIF 139
++ D + GMP + T+ + T + +H PGHTPG + F
Sbjct: 128 IDRIQDSGEMYGMPEARIFVTDRWLDDGDTVTLGETEFEVFHCPGHTPGHVVFFHRETKF 187
Query: 140 S--GDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAER 194
+ GD +F SIGR DFP N +D+ +S+ + + +D+ PGHG ++F AER
Sbjct: 188 AQVGDVLFQGSIGRTDFPMGNHQDLIDSITQ-KLWPLGEDVRFVPGHGPMSTFGAER 243
>ref|NP_344443.1| (NC_002754) Conserved hypothetical protein [Sulfolobus
solfataricus]
gb|AAK43233.1| (AE006903) Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 209
Score = 75.9 bits (185), Expect = 3e-13
Identities = 56/187 (29%), Positives = 94/187 (49%), Gaps = 11/187 (5%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAK---NPKAILITHGHYDHVWDGAQLS 65
G + N+Y+V ++ IID G SE + K N + I+ THGH+DH+ Q+
Sbjct: 9 GPLATNSYLV-IAGKEGVIIDAGGDMSELIQTVRKEKINIRYIIATHGHFDHIMGVNQIK 67
Query: 66 KLLKNTPIYAPKDDVFMLE--NDIFHLGMPVFSPNFSVPCN--KGCTTLEIANTTIKYWH 121
+ ++ + D+ +L+ + + + + + + P K +E+ +K
Sbjct: 68 RDFPSSTFLINEKDLGLLKRASSMAQSFLNLLISDVTKPDGFVKEGDEIELGGEKLKIIE 127
Query: 122 FPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIY 181
PGHT G I G IF+GD +FY ++GR D +EK ++ESL + + L P +I +Y
Sbjct: 128 TPGHTMGSICIIANGYIFTGDTLFYGTVGRTDLG-GSEKLLRESLEKLKKL--PDEIIVY 184
Query: 182 PGHGDKT 188
PGHG T
Sbjct: 185 PGHGPFT 191
>ref|NP_521387.1| (NC_003295) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
emb|CAD17056.1| (AL646074) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
Length = 224
Score = 75.5 bits (184), Expect = 4e-13
Identities = 61/199 (30%), Positives = 89/199 (44%), Gaps = 25/199 (12%)
Query: 12 EENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKA----ILITHGHYDHVWDGAQLSKL 67
E+N ++ G + DPG + +L A+ A IL+THGH DH L
Sbjct: 18 EQNCTLLIGDDGRAAVTDPG-GDIDRILSAARQQGARIEKILLTHGHVDHCAAADALRTQ 76
Query: 68 LKNTPIYAP-KDDVFMLENDIFHLGMPVFSPNFSVPCNKGCT---------TLEIANTTI 117
L PI P +D+ F ++ +P S F P + T+E A T+
Sbjct: 77 L-GVPIEGPHRDEAFWIDQ------LPTQSQRFGFPPARAFVPDRWLDDGDTVEAAGRTL 129
Query: 118 KYWHFPGHTPGCSII--EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFP 175
+ +H PGHTPG + + + GD +F SIGR DFP N D+ S +R +
Sbjct: 130 EVFHCPGHTPGHVVFFSRPDRIAIVGDVLFAGSIGRTDFPRGNHADLIRS-IRTKLWPLG 188
Query: 176 KDIEIYPGHGDKTSFFAER 194
D+ PGHG ++F ER
Sbjct: 189 DDVTFVPGHGPVSTFGDER 207
>ref|NP_378011.1| (NC_003106) 199aa long conserved hypothetical protein [Sulfolobus
tokodaii]
dbj|BAB67120.1| (AP000988) 199aa long conserved hypothetical protein [Sulfolobus
tokodaii]
Length = 199
Score = 75.5 bits (184), Expect = 4e-13
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 18/199 (9%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSE---WVLENAKNPKAILITHGHYDH 57
M + R G N Y+V +S +ID + SE ++L N K+I THGH+DH
Sbjct: 2 MIVKRFILGEYSTNTYLV-VSGDEGILIDVAENPSEVIDYILTNNIKLKSIYATHGHFDH 60
Query: 58 VWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPV--FSPNFSVPCNKGCTTLEIANT 115
V ++ K N P + + D+ +L D G+ F S+ ++I N
Sbjct: 61 VLGVTEVKKYF-NVPFFLHRSDLDLLRRDERTKGIVPDGFIDEKSI--------IKIGNE 111
Query: 116 TIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFP 175
+K PGHT G + IF+GD +F SIGRYD ++ +K+SL R L+
Sbjct: 112 ELKVIETPGHTMGSVCYIFDDGIFTGDTLFNGSIGRYDLG-GDKNLLKKSLNRLMELN-- 168
Query: 176 KDIEIYPGHGDKTSFFAER 194
+ +YPGHG T+ E+
Sbjct: 169 DGLTVYPGHGFFTTLGYEK 187
>ref|NP_405002.1| (NC_003143) metallo-beta-lactamase superfamily protein [Yersinia
pestis]
emb|CAC90238.1| (AJ414148) metallo-beta-lactamase superfamily protein [Yersinia
pestis]
Length = 215
Score = 75.1 bits (183), Expect = 5e-13
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 23/190 (12%)
Query: 21 SSGIDFIIDPGFSSSEWVLENAKNPKAI---LITHGHYDHVWDGAQLSKLLKNTPIYAP- 76
++G ++DPG +++ + E + I L+THGH DHV A+++ + PIY P
Sbjct: 22 ATGQAALVDPGGEATKIIAEVERQGVTISQVLLTHGHLDHVGAAAEVAAHFQ-VPIYGPE 80
Query: 77 KDDVFMLENDIFHLGMPVFSPNFSV-PCNKGCTT--------LEIANTTIKYWHFPGHTP 127
K+D F LE G+P S F + C T + + + H PGHTP
Sbjct: 81 KEDTFWLE------GLPAQSRMFGLSECEAFTPTRWLEEGDKITVGEIELSVLHCPGHTP 134
Query: 128 GCSI-IEIEG-VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
G + I+ +G + GD IF +GR DFP + + + S +R + L DI PGHG
Sbjct: 135 GHIVFIDPQGRLALVGDVIFKGGVGRSDFPRGDHQQLINS-IRTKLLPLGDDITFIPGHG 193
Query: 186 DKTSFFAERE 195
++ ER+
Sbjct: 194 PMSTLGHERQ 203
>ref|NP_455483.1| (NC_003198) conserved hypothetical protein [Salmonella enterica
subsp. enterica serovar Typhi]
emb|CAD05397.1| (AL627268) conserved hypothetical protein [Salmonella enterica
subsp. enterica serovar Typhi]
Length = 215
Score = 74.7 bits (182), Expect = 6e-13
Identities = 57/194 (29%), Positives = 90/194 (46%), Gaps = 25/194 (12%)
Query: 27 IIDPGFSSSEWVLE---NAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAP-KDDVFM 82
++DPG + + E + IL+THGH DHV ++L++ P+ P K+D F
Sbjct: 28 LVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHY-GVPVIGPEKEDEFW 86
Query: 83 LENDIFHLGMPVFSPNFSVP----------CNKGCTTLEIANTTIKYWHFPGHTPGCSII 132
L+ G+P S F + N G + + N T++ H PGHTPG +
Sbjct: 87 LQ------GLPAQSRMFGLDECQPLTPDRWLNDG-DRVSVGNVTLQVLHCPGHTPGHVVF 139
Query: 133 --EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSF 190
E ++ SGD IF +GR DFP + + +++ R + L D+ PGHG ++
Sbjct: 140 FDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKR-KLLPLGDDVTFIPGHGPLSTL 198
Query: 191 FAEREHSKIWVSRM 204
ER H+ M
Sbjct: 199 GYERLHNSFLQDEM 212
>ref|NP_459972.1| (NC_003197) putative Metallo-beta-lactamase [Salmonella typhimurium
LT2]
gb|AAL19931.1| (AE008743) putative Metallo-beta-lactamase [Salmonella typhimurium
LT2]
Length = 215
Score = 74.3 bits (181), Expect = 8e-13
Identities = 56/187 (29%), Positives = 89/187 (46%), Gaps = 25/187 (13%)
Query: 27 IIDPGFSSSEWVLE---NAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAP-KDDVFM 82
++DPG + + E + IL+THGH DHV ++L++ P+ P K+D F
Sbjct: 28 LVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHY-GVPVIGPEKEDEFW 86
Query: 83 LENDIFHLGMPVFSPNFSVP----------CNKGCTTLEIANTTIKYWHFPGHTPGCSII 132
L+ G+P S F + N G + + N T++ H PGHTPG +
Sbjct: 87 LQ------GLPAQSRMFGLDECQPLTPDRWLNDG-DRVSVGNVTLQVLHCPGHTPGHVVF 139
Query: 133 --EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSF 190
E ++ SGD IF +GR DFP + + +++ R + L D+ PGHG ++
Sbjct: 140 FDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKR-KLLPLGDDVTFIPGHGPLSTL 198
Query: 191 FAEREHS 197
ER H+
Sbjct: 199 GYERLHN 205
>ref|NP_243686.1| (NC_002570) BH2820~unknown conserved protein [Bacillus halodurans]
dbj|BAB06539.1| (AP001516) BH2820~unknown conserved protein [Bacillus halodurans]
Length = 211
Score = 73.2 bits (178), Expect = 2e-12
Identities = 55/198 (27%), Positives = 92/198 (45%), Gaps = 14/198 (7%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSE---WVLENAKNPKAILITHGHYDHVWDGAQLS 65
G ++ N YI G I DPG + W+ + P AIL+TH H+DH+ +
Sbjct: 9 GPLQTNWYIQTNDQGEGIIFDPGGEVEKLITWLRDRQITPLAILLTHAHFDHIGAVEDVR 68
Query: 66 KLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNK------GCTTLEIANTTIKY 119
+ P+Y +++ L D G +F P S+ + G L I + + +
Sbjct: 69 NTF-HIPVYIHENEKEWL-IDPQRNGSSLFIPGSSIKAREAEHLITGEQDLSIGSFSYQV 126
Query: 120 WHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKD 177
PGH+PG + + ++FSGD +F SIGR D P + + + +S + + L+ P+D
Sbjct: 127 LETPGHSPGSLSYYAKEDKIVFSGDALFAGSIGRTDLPGGDHQLLLDS-IHDKLLELPED 185
Query: 178 IEIYPGHGDKTSFFAERE 195
+ GHG T+ E +
Sbjct: 186 TTVASGHGPTTTIGHEMD 203
>ref|NP_147830.1| (NC_000854) hypothetical protein [Aeropyrum pernix]
pir||D72599 hypothetical protein APE1260 - Aeropyrum pernix (strain K1)
dbj|BAA80250.1| (AP000061) 209aa long hypothetical protein [Aeropyrum pernix]
Length = 209
Score = 72.8 bits (177), Expect = 2e-12
Identities = 61/206 (29%), Positives = 92/206 (44%), Gaps = 14/206 (6%)
Query: 1 MEILRR-ECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAK-NPKAILITHGHYDHV 58
MEIL R G ++ N Y+ + G ++DPG LE + +THGH+DHV
Sbjct: 1 MEILERLSLGVLQVNTYVAA-AGGECLVVDPGGPEVLEALERLGCRDIVVALTHGHFDHV 59
Query: 59 WDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFS----PNFSVPCNK-GCTTLEIA 113
A + L + A + LG+ + P SV +TL A
Sbjct: 60 ---AGVEHLAARGAVVAAHPQTPRVAEAYADLGVKMGYLKGVPRISVDVELVDGSTLRAA 116
Query: 114 NTTIKYWHFPGHTPGCSII--EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
++K H PGH+P ++ + G+ F+GD IF SIGR D + + M SL R
Sbjct: 117 GLSLKAIHTPGHSPDHIVLYDQARGLAFTGDLIFRGSIGRVDIALGDGEAMARSLARIVR 176
Query: 172 LDFPKDIEIYPGHGDKTSFFAEREHS 197
+ P+ + PGHG +T+ E H+
Sbjct: 177 -ELPRGTRLLPGHGPETTLEYEILHN 201
>ref|NP_230915.1| (NC_002505) glyoxylase II family protein [Vibrio cholerae]
pir||F82220 glyoxylase II family protein VC1270 [imported] - Vibrio cholerae
(group O1 strain N16961)
gb|AAF94429.1| (AE004206) glyoxylase II family protein [Vibrio cholerae]
Length = 218
Score = 70.9 bits (172), Expect = 9e-12
Identities = 58/203 (28%), Positives = 89/203 (43%), Gaps = 27/203 (13%)
Query: 10 AVEENAYIVKLSSGID-FIIDPGFSSSEWVL---ENAKNPKAILITHGHYDHVWDGAQLS 65
A +N IV ++ ++DPG + + E +++THGH DHV L+
Sbjct: 12 AFAQNCSIVWCDETMEGIVVDPGGDVKQLAMLIAELGVKVTQLVLTHGHLDHVGGTQSLA 71
Query: 66 KLLKNTPIYAP-KDDVFMLENDIFHLGMPVFSPNFSVPCNKGC---------TTLEIANT 115
+ L T + P K D F L+ G+ S F P + +
Sbjct: 72 QALGGTRVVGPHKADNFWLQ------GLEGQSKMFGFPLTEAFEPDEWLDDGDVIHFGQQ 125
Query: 116 TIKYWHFPGHTPGCSII--EIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLD 173
T++ H PGHTPG ++ E + F GD +F SIGR DFP + D + +N
Sbjct: 126 TLQVIHTPGHTPGHVVLFSEAARLAFVGDVLFNGSIGRTDFP---QGDFNTLIASIKNKL 182
Query: 174 FP--KDIEIYPGHGDKTSFFAER 194
+P D+ PGHG +++F ER
Sbjct: 183 WPLGSDVTFIPGHGPQSTFGRER 205
>ref|NP_599572.1| (NC_003450) COG0491:Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum]
Length = 211
Score = 70.1 bits (170), Expect = 1e-11
Identities = 57/196 (29%), Positives = 87/196 (44%), Gaps = 15/196 (7%)
Query: 11 VEENAYIVKLSSGIDFIIDPGFSSSEWV-LENAKNPKAILITHGHYDHVWDGAQLSKLLK 69
V+ N ++V + FIID +++ + + K IL TH H DH+ +LSK
Sbjct: 26 VDNNIWVVGNDDEV-FIIDAAHTAAPIIEAVGGRAVKGILCTHAHNDHITVAPELSKEF- 83
Query: 70 NTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG- 128
+ PI+ D + E +L + +IA T + + PGH+PG
Sbjct: 84 DAPIFVHPGDQMLWEETHGNLTHEDLADQ---------QKFQIAGTELIVLNTPGHSPGS 134
Query: 129 -CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDK 187
C + +FSGD +F G YS+ + ESL + LD P + + GHGD
Sbjct: 135 SCFYLPEANELFSGDTLFQGGPGATGRKYSSFDTIIESL-KTSILDLPAETTVRTGHGDH 193
Query: 188 TSFFAEREHSKIWVSR 203
TS AE H + W+ R
Sbjct: 194 TSVGAEAPHLEEWIKR 209
>ref|NP_439805.1| (NC_000907) conserved hypothetical protein [Haemophilus influenzae
Rd]
sp|Q57544|YCBL_HAEIN Hypothetical protein HI1663
pir||D64174 probable hydrolase (EC 3.-.-.-) HI1663 - Haemophilus influenzae
(strain Rd KW20)
gb|AAC23309.1| (U32839) conserved hypothetical protein [Haemophilus influenzae Rd]
Length = 212
Score = 68.9 bits (167), Expect = 3e-11
Identities = 58/183 (31%), Positives = 83/183 (44%), Gaps = 22/183 (12%)
Query: 27 IIDPGFSSSEWVL---ENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFML 83
IIDPG + + E N K +L+THGH DHV QL + + + D F+
Sbjct: 27 IIDPGGEAERLIQRIEELDLNLKVLLLTHGHLDHVGAAMQLKQHFGVEIWGSNEKDKFLF 86
Query: 84 ENDIFHLGMPVFSPNFSVP----------CNKGCTTLEIANTTIKYWHFPGHTPG-CSII 132
E+ +P + F +P N+ L++ + H PGHTPG I
Sbjct: 87 ES------LPEQAQRFGLPNIDAFLPDRWFNQEGEILKLDGFNFEILHLPGHTPGHIGFI 140
Query: 133 EIE-GVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFF 191
E E V F+GD +F IGR DFP + + + S +R + L DI I GHG T+
Sbjct: 141 EHEKKVAFTGDVLFQGGIGRTDFPRGDYETLISS-IRTKLLPLNDDIIIIAGHGSYTTIG 199
Query: 192 AER 194
E+
Sbjct: 200 QEK 202
>ref|NP_245209.1| (NC_002663) unknown [Pasteurella multocida]
gb|AAK02356.1| (AE006062) unknown [Pasteurella multocida]
Length = 209
Score = 68.9 bits (167), Expect = 3e-11
Identities = 57/183 (31%), Positives = 90/183 (49%), Gaps = 16/183 (8%)
Query: 27 IIDPGFSSSEWVL---ENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKD----- 78
IIDPG + + + E N +AIL+THGH DHV +L K N I P
Sbjct: 27 IIDPGGDAEKLIKRIEELDLNLQAILLTHGHLDHVGAAPKL-KAHFNVEIIGPNSQDEYW 85
Query: 79 -DVFMLENDIFHL-GMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG-CSIIEIE 135
+ ++ F L +P F+P+ + N +++ + + H PGHTPG IE E
Sbjct: 86 FNALPAQSQKFGLFEIPAFTPDRWL--NNEGEIIQVGDMQFEVLHLPGHTPGHIGFIEHE 143
Query: 136 -GVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAER 194
+ F+GD +F +SIGR DF + + S+++ + D+ I GHG T+ E+
Sbjct: 144 KRIAFTGDVLFKQSIGRTDFQGGDHATLL-SVIKEKLYPLGDDMIIVAGHGPYTTIGQEK 202
Query: 195 EHS 197
+H+
Sbjct: 203 QHN 205
>gb|EAA02936.1| (AAAB01007382) ebiP1693 [Anopheles gambiae str. PEST]
Length = 210
Score = 68.6 bits (166), Expect = 4e-11
Identities = 55/197 (27%), Positives = 87/197 (43%), Gaps = 14/197 (7%)
Query: 13 ENAYIVKLSSGIDFIIDPGF-------SSSEWVLENAKNPKAILITHGHYDHVWDGAQLS 65
EN YIV +IIDPG + ++ +N + IL+TH H DH+ G Q +
Sbjct: 14 ENTYIVYNDQKQAWIIDPGNVHPKETEALQSFISDNGLKVEKILLTHAHIDHIL-GLQWA 72
Query: 66 KLLKNTPIYAPKDDVFMLENDIF---HLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHF 122
P+Y D+ +L+ G N V L++ + +
Sbjct: 73 HDTYKVPVYLHPDEEEILKMGNLSAQRFGFEFNDFNGEVKFLNEGDELKLGDDVFHIYFT 132
Query: 123 PGHTPGCSIIEIEG--VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
PGH+PG I SGD +F SIGR D +N + +S+ + + L P+D ++
Sbjct: 133 PGHSPGSITYHNPDGKFIISGDVLFEGSIGRTDLFKANFDQLIDSI-KTKLLILPEDTQV 191
Query: 181 YPGHGDKTSFFAEREHS 197
+ GHG+ T E+EH+
Sbjct: 192 FSGHGNPTKIGFEKEHN 208
>ref|NP_604059.1| (NC_003454) Hydroxyacylglutathione hydrolase [Fusobacterium
nucleatum subsp. nucleatum ATCC 25586]
gb|AAL95358.1| (AE010622) Hydroxyacylglutathione hydrolase [Fusobacterium
nucleatum subsp. nucleatum ATCC 25586]
Length = 207
Score = 68.6 bits (166), Expect = 4e-11
Identities = 53/192 (27%), Positives = 81/192 (41%), Gaps = 8/192 (4%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSE----WVLENAKNPKAILITHGHYDHVWDGAQL 64
GA N ++ + I + D G + E ++ E+ + K I++THGH DH+ L
Sbjct: 9 GAYGTNCFLAYDENNIAYFFDCGGRNLEKVYEFISEHNLDLKYIVLTHGHGDHIEGLNDL 68
Query: 65 SKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPG 124
+ +Y ++D L N L +F F K PG
Sbjct: 69 ASHYPEAKVYIGEEDKDFLYNSELSLSDAIFGEFFKFKGEIHTVKESDMVGDFKVIDTPG 128
Query: 125 HTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYP 182
HT G E + ++ SGD +F RS GRYD P + + + SL + L P + +Y
Sbjct: 129 HTIGSKSFYYEKDKILISGDTLFRRSYGRYDLPTGSLEMLCHSLKKLSKL--PDETVVYN 186
Query: 183 GHGDKTSFFAER 194
GH D T+ ER
Sbjct: 187 GHTDNTTIGEER 198
>dbj|BAB97713.1| (AP005274) Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum ATCC 13032]
Length = 179
Score = 68.6 bits (166), Expect = 4e-11
Identities = 54/181 (29%), Positives = 80/181 (43%), Gaps = 14/181 (7%)
Query: 26 FIIDPGFSSSEWV-LENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLE 84
FIID +++ + + K IL TH H DH+ +LSK + PI+ D + E
Sbjct: 8 FIIDAAHTAAPIIEAVGGRAVKGILCTHAHNDHITVAPELSKEF-DAPIFVHPGDQMLWE 66
Query: 85 NDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFSGD 142
+L + +IA T + + PGH+PG C + +FSGD
Sbjct: 67 ETHGNLTHEDLADQ---------QKFQIAGTELIVLNTPGHSPGSSCFYLPEANELFSGD 117
Query: 143 FIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVS 202
+F G YS+ + ESL + LD P + + GHGD TS AE H + W+
Sbjct: 118 TLFQGGPGATGRKYSSFDTIIESL-KTSILDLPAETTVRTGHGDHTSVGAEAPHLEEWIK 176
Query: 203 R 203
R
Sbjct: 177 R 177
>ref|NP_302290.1| (NC_002677) putative glyoxylase II [Mycobacterium leprae]
emb|CAC30867.1| (AL583923) putative glyoxylase II [Mycobacterium leprae]
Length = 238
Score = 66.6 bits (161), Expect = 2e-10
Identities = 52/191 (27%), Positives = 86/191 (44%), Gaps = 29/191 (15%)
Query: 15 AYIV-KLSSGIDFIIDPGFSSSEWV--LE-NAKNPKAILITHGHYDHVWD---GAQLSKL 67
AY++ +G ++DP +++ + V LE + +L+TH H DHV G QL L
Sbjct: 32 AYLIGDRQTGDCVVVDPAYAAGDLVDALEADGMRLSGVLVTHHHPDHVGGVMMGFQLKGL 91
Query: 68 LK-----NTPIYAPKDDVFMLEN----DIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIK 118
+ P++ + + DI HL ++ L + + I+
Sbjct: 92 TELLERVTVPVHVNTHEALWISRVTGIDIGHL-----------TTHEHRDKLSVGDIEIE 140
Query: 119 YWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDI 178
H PGHTPG ++G++ +GD +F GR DFP N +M SL + L P +
Sbjct: 141 LLHTPGHTPGSQCFLLDGLLVAGDTLFLEGCGRTDFPGGNSDEMYRSLQQLAQL--PGNP 198
Query: 179 EIYPGHGDKTS 189
++PGH T+
Sbjct: 199 TVFPGHWYSTA 209
>ref|NP_646314.1| (NC_003923) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus MW2]
dbj|BAB95362.1| (AP004827) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 207
Score = 65.9 bits (159), Expect = 3e-10
Identities = 51/200 (25%), Positives = 88/200 (43%), Gaps = 16/200 (8%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWV--LENAKNP-KAILITHGHYDH 57
M I G V+ N Y ++ + +IDP S + + L P KAIL+TH H+DH
Sbjct: 1 MRISSLTLGLVDTNTYFIENDKAV-ILIDPSGESGKIIKKLNQINKPLKAILLTHAHFDH 59
Query: 58 VWDGAQLSKLLKNTPIYAPKDDVFMLENDIFH-------LGMPVFSPNFSVP-CNKGCTT 109
+ + + P+Y + + L++ + + G+P+ + + N+G T
Sbjct: 60 IGAVDDIVDRF-DVPVYMHEAEFDFLKDPVKNGADKFKQYGLPIITSKVTPEKLNEGST- 117
Query: 110 LEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRF 169
EI H PGH+PG + GD +F IGR D Y + + ++
Sbjct: 118 -EIEGFKFNVLHTPGHSPGSLTYVFDEFAVVGDTLFNNGIGRTDL-YKGDYETLVDSIQD 175
Query: 170 QNLDFPKDIEIYPGHGDKTS 189
+ + D+ ++PGHG T+
Sbjct: 176 KIFELEGDLPLFPGHGPYTT 195
>ref|NP_372069.1| (NC_002758) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus Mu50]
ref|NP_374658.1| (NC_002745) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus N315]
dbj|BAB42637.1| (AP003134) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus N315]
dbj|BAB57707.1| (AP003362) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus Mu50]
Length = 207
Score = 65.9 bits (159), Expect = 3e-10
Identities = 51/200 (25%), Positives = 88/200 (43%), Gaps = 16/200 (8%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWV--LENAKNP-KAILITHGHYDH 57
M I G V+ N Y ++ + +IDP S + + L P KAIL+TH H+DH
Sbjct: 1 MRISSLTLGLVDTNTYFIENDKAV-ILIDPSGESEKIIKKLNQINKPLKAILLTHAHFDH 59
Query: 58 VWDGAQLSKLLKNTPIYAPKDDVFMLENDIFH-------LGMPVFSPNFSVP-CNKGCTT 109
+ + + P+Y + + L++ + + G+P+ + + N+G T
Sbjct: 60 IGAVDDIVDRF-DVPVYMHEAEFDFLKDPVKNGADKFKQYGLPIITSKVTPEKLNEGST- 117
Query: 110 LEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRF 169
EI H PGH+PG + GD +F IGR D Y + + ++
Sbjct: 118 -EIEGFKFNVLHTPGHSPGSLTYVFDEFAVVGDTLFNNGIGRTDL-YKGDYETLVDSIQD 175
Query: 170 QNLDFPKDIEIYPGHGDKTS 189
+ + D+ ++PGHG T+
Sbjct: 176 KIFELEGDLPLFPGHGPYTT 195
>ref|NP_471602.1| (NC_003212) similar to unknown proteins [Listeria innocua]
emb|CAC97498.1| (AL596171) similar to unknown proteins [Listeria innocua]
Length = 205
Score = 64.7 bits (156), Expect = 6e-10
Identities = 54/200 (27%), Positives = 86/200 (43%), Gaps = 9/200 (4%)
Query: 2 EILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAK---NPKAILITHGHYDHV 58
+I R G ++EN YI+ + I+DPG +++ E A P A+L+TH HYDH+
Sbjct: 3 KIKRIMTGIIQENCYII-YQDNLALIVDPGDEANKIEAEIASLGVKPIAVLLTHCHYDHI 61
Query: 59 WDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTL---EIANT 115
++ + P+Y + L N +L + + TL I
Sbjct: 62 GALEEIRSTYQ-IPVYVSPLEQEWLSNPDLNLSAHIAGKAIIAQPAEYEFTLGDYNIEGF 120
Query: 116 TIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFP 175
K PGH+ G + GD +F SIGR D Y+ + D + ++ + P
Sbjct: 121 RFKVVPTPGHSIGSVSFIFDDFAVVGDALFKGSIGRTDL-YTGDFDTLINSIKTELFVLP 179
Query: 176 KDIEIYPGHGDKTSFFAERE 195
D Y GHGD T+ E++
Sbjct: 180 DDFAAYSGHGDATTIGHEKK 199
>ref|NP_069409.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
pir||G69321 conserved hypothetical protein AF0575 - Archaeoglobus fulgidus
gb|AAB90665.1| (AE001065) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 209
Score = 63.2 bits (152), Expect = 2e-09
Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 28/187 (14%)
Query: 11 VEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKA---ILITHGHYDHVWDGAQLSKL 67
++E ++ + I FI++ L+ +P+ I++TH HYDH +
Sbjct: 19 LDEKKALIDVGGDIQFILN--------ALKRYIDPRELDYIILTHSHYDHAAAAGHFKGI 70
Query: 68 LKNTPIYAPKDDVFMLEND-----IFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHF 122
K I KD+ +L+ +F + F P+ + +G +E+ +++ H
Sbjct: 71 AK---IAIHKDEYSLLKAQGFTSFMFGVSFKKFEPDIML---EGGEVIELGELSLEVIHT 124
Query: 123 PGHTPG--CSIIEIEGVIFSGDFIF-YRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIE 179
PGH+PG C +FSGD +F + S GR D P + +++ SL + LD
Sbjct: 125 PGHSPGSICLYEPERKWLFSGDTVFAHGSFGRVDLPGGSARELINSLEKLSKLDVE---N 181
Query: 180 IYPGHGD 186
+YPGH D
Sbjct: 182 LYPGHED 188
>ref|NP_614917.1| (NC_003551) Zn-dependent hydrolase [Methanopyrus kandleri AV19]
gb|AAM02847.1| (AE010452) Zn-dependent hydrolase [Methanopyrus kandleri AV19]
Length = 211
Score = 62.0 bits (149), Expect = 4e-09
Identities = 38/143 (26%), Positives = 66/143 (45%), Gaps = 12/143 (8%)
Query: 49 LITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLEND------IFHLGMPVFSPNFSVP 102
L+TH H+DH G + ++ + +V +D +F MP + P+F+
Sbjct: 53 LLTHSHFDHAAAGPDALEAGLEVGVHRAEAEVLREGDDRLSAAYLFGRPMPAYEPSFTF- 111
Query: 103 CNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDM 162
+ T ++ ++ + PGH+PG + + F+GD +F GR+D P + K +
Sbjct: 112 --RDGETFDVGGEEVEVLYTPGHSPGSCCFLLGDLAFTGDTVFGFGPGRWDLPGGDRKKL 169
Query: 163 KESLLRFQNLDFPKDIEIYPGHG 185
ESL R + I+PGHG
Sbjct: 170 CESLERLLSTGVR---SIFPGHG 189
>ref|NP_359083.1| (NC_003098) Conserved hypothetical protein [Streptococcus
pneumoniae R6]
gb|AAL00294.1| (AE008517) Conserved hypothetical protein [Streptococcus pneumoniae
R6]
Length = 226
Score = 61.6 bits (148), Expect = 5e-09
Identities = 53/197 (26%), Positives = 91/197 (45%), Gaps = 21/197 (10%)
Query: 13 ENAYIVKLSSGIDFIIDPGFSSSEW-----VLENAKNPK-AILITHGHYDHVWDGAQLSK 66
EN Y ++ + ++DPG S W +E P AIL+TH HYDH+ + +
Sbjct: 30 ENTYYLEGEKHL-IVVDPG---SHWEAIRQTIEKINKPICAILLTHAHYDHIMSLDLVCE 85
Query: 67 LLKNTPIYAPKDDVFMLENDIFHL-GMPVFSPNFSVPCNKGCTTLEI-ANTTIKYWHF-- 122
N P+Y + + L + +L G+P V T ++ +HF
Sbjct: 86 TFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMADVVTKPAEHTFVFHEEYQLEEFHFKV 145
Query: 123 ---PGHT-PGCSIIEIEG-VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKD 177
PGH+ G S++ + ++ +GD +F +IGR D P + + + S ++ Q P +
Sbjct: 146 LPTPGHSIGGVSLVFPDAHLVLTGDALFRETIGRTDLPTGSMEQLLHS-IQTQLFTLP-N 203
Query: 178 IEIYPGHGDKTSFFAER 194
++YPGHG T+ E+
Sbjct: 204 YDVYPGHGSATTIAHEK 220
>ref|NP_606880.1| (NC_003485) conserved hypothetical protein [Streptococcus pyogenes
MGAS8232]
gb|AAL97379.1| (AE010003) conserved hypothetical protein [Streptococcus pyogenes
MGAS8232]
Length = 232
Score = 61.2 bits (147), Expect = 7e-09
Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 13 ENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPK---AILITHGHYDHVWDGAQLSKLLK 69
EN Y + + +IDPG + E + + K AIL+TH HYDH++ +
Sbjct: 34 ENTYYLVNDQAV-ILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFD 92
Query: 70 NTPIYAPKDDVFMLENDIFHL-GMPVFSPNFSVPCNKGCTTLEIANT-TIKYWHF----- 122
+ P+Y + + L + +L G+ +V ++ + + F
Sbjct: 93 HPPVYVSEKEAAWLSSPDDNLSGLGRHDDIINVIARPAENFFKLKQPYQLNGFEFTVLPT 152
Query: 123 PGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
PGH+ G + + ++ +GD +F +IGR D P SN +D+ +R + P +
Sbjct: 153 PGHSLGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITG-IRQELFTLPNHYRV 211
Query: 181 YPGHGDKTSFFAER 194
YPGHG T+ E+
Sbjct: 212 YPGHGPSTTICHEK 225
>ref|NP_386438.1| (NC_003047) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
emb|CAC46911.1| (AL591790) CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti]
Length = 213
Score = 61.2 bits (147), Expect = 7e-09
Identities = 51/178 (28%), Positives = 78/178 (43%), Gaps = 12/178 (6%)
Query: 27 IIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFML 83
++DPG + + EN KAI +THGH DH +L + L + KDD+ +L
Sbjct: 29 VVDPGGDVDIILQTIRENGIALKAIWLTHGHIDHAGGAKELKEALGLDIVGPHKDDLPLL 88
Query: 84 EN-----DIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSII--EIEG 136
E + F L M V + +G T+ + + H PGH PG + +
Sbjct: 89 ERLEDQAERFGLAMKVQNVVPDRWLEEG-DTVSFGDHVFEVLHCPGHAPGHVVYFNRAQN 147
Query: 137 VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAER 194
GD +F+ SIGR D P N + + +S +R + L ++ GHG ER
Sbjct: 148 FAHVGDVLFHGSIGRTDLPGGNHQQLLDS-IRDKILPLGDNVGFICGHGPGGQIGEER 204
>ref|NP_215148.1| (NC_000962) hypothetical protein Rv0634c [Mycobacterium
tuberculosis H37Rv]
ref|NP_335072.1| (NC_002755) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
pir||G70612 hypothetical protein Rv0634c - Mycobacterium tuberculosis (strain
H37RV)
emb|CAB07123.1| (Z92772) hypothetical protein Rv0634c [Mycobacterium tuberculosis
H37Rv]
gb|AAK44886.1| (AE006961) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
Length = 237
Score = 61.2 bits (147), Expect = 7e-09
Identities = 47/182 (25%), Positives = 87/182 (46%), Gaps = 21/182 (11%)
Query: 15 AYIV-KLSSGIDFIIDPGFSSSEWV--LENAKNP-KAILITHGHYDHVWDGAQ------L 64
AY++ ++G ++DP +++ + + LE+ +L+TH H DHV L
Sbjct: 31 AYLIGDRTTGDCVVVDPAYAAGDLLDALESDDMQLSGVLVTHHHPDHVGGSMMGFQLPGL 90
Query: 65 SKLLK--NTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHF 122
++LL+ + P++ + + G+PV + ++ + + + I+ H
Sbjct: 91 AELLERASVPVHVNTHEALWVSRVT---GIPVGD----LITHEHGDKVSVGDIDIELLHT 143
Query: 123 PGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYP 182
PGHTPG ++G + +GD +F GR DFP + +M SL + L P D ++P
Sbjct: 144 PGHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFPGGDSDEMYRSLRQLAEL--PGDPTVFP 201
Query: 183 GH 184
GH
Sbjct: 202 GH 203
>ref|NP_390359.1| (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
sp|P54501|YQGX_BACSU Hypothetical protein yqgX
pir||A69958 conserved hypothetical protein yqgX - Bacillus subtilis
dbj|BAA12527.1| (D84432) YqgX [Bacillus subtilis]
emb|CAB14410.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]
Length = 211
Score = 60.8 bits (146), Expect = 9e-09
Identities = 51/206 (24%), Positives = 97/206 (46%), Gaps = 12/206 (5%)
Query: 1 MEILRRECGAVEENAYIVKLSSGIDFIIDPGFSS---SEWVLENAKNPKAILITHGHYDH 57
M+ R G ++ NAY + +S I DPG ++++ E P AIL+TH H+DH
Sbjct: 1 MKWRRMPVGPIQANAYFL-ISDDQCLIFDPGGEGHKINQYIKEKGLTPLAILLTHAHFDH 59
Query: 58 VWDGAQLSKLLKNTPIYAPKDDV-FMLENDIFHLGMPVFSPNFSVPCN---KGCTTLEIA 113
+ ++ + + P+Y +++ ++ + + GM + P + +G L I
Sbjct: 60 IGALDEVREKW-DIPVYLHQNEKNWLADASLNGSGMLRGIEVTAKPADHLIEGDGELNIG 118
Query: 114 NTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
++ PGH+PG ++ ++ SGD +F IGR D N++ + S + +
Sbjct: 119 PFHLETLFTPGHSPGSVSYYVKDADLVISGDVLFQGGIGRTDLIGGNQETLLTS-IHEKL 177
Query: 172 LDFPKDIEIYPGHGDKTSFFAEREHS 197
L P+ + GHG +T E++ +
Sbjct: 178 LTLPEHTLVLSGHGPETDVLTEQDQN 203
>ref|NP_346086.1| (NC_003028) metallo-beta-lactamase superfamily protein
[Streptococcus pneumoniae TIGR4]
gb|AAK75726.1| (AE007458) metallo-beta-lactamase superfamily protein
[Streptococcus pneumoniae TIGR4]
Length = 209
Score = 60.8 bits (146), Expect = 9e-09
Identities = 52/197 (26%), Positives = 89/197 (44%), Gaps = 21/197 (10%)
Query: 13 ENAYIVKLSSGIDFIIDPGFSSSEW-----VLENAKNPK-AILITHGHYDHVWDGAQLSK 66
EN Y ++ + ++DPG S W +E P AIL+TH HYDH+ + +
Sbjct: 13 ENTYYLEGEKHL-IVVDPG---SHWEAIRQTIEKINKPICAILLTHAHYDHIMSLDLVRE 68
Query: 67 LLKNTPIYAPKDDVFMLENDIFHL-GMPVFSPNFSVPCNKGCTTL------EIANTTIKY 119
N P+Y + + L + +L G+P V T ++ K
Sbjct: 69 TFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMADVVTKPAEHTFVFHEEYQLEEFRFKV 128
Query: 120 WHFPGHT-PGCSIIEIEG-VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKD 177
PGH+ G S++ + ++ +GD +F +IGR D P + + + S ++ Q P +
Sbjct: 129 LPTPGHSIGGVSLVFPDAHLVLTGDALFRETIGRTDLPTGSMEQLLHS-IQTQLFTLP-N 186
Query: 178 IEIYPGHGDKTSFFAER 194
++YPGHG T+ E+
Sbjct: 187 YDVYPGHGPATTIAHEK 203
>ref|NP_625044.1| (NC_003888) putative hydrolase [Streptomyces coelicolor A3(2)]
emb|CAC14942.1| (AL449216) putative hydrolase [Streptomyces coelicolor A3(2)]
Length = 209
Score = 60.1 bits (144), Expect = 2e-08
Identities = 47/159 (29%), Positives = 71/159 (44%), Gaps = 12/159 (7%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKG 106
AI+ TH H DHV D A I+ +DD+ ++ P +P+ +
Sbjct: 59 AIVCTHAHNDHV-DAAPALAERTGATIWLHRDDL-----PLWQQTHPDRAPDAWLTDG-- 110
Query: 107 CTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKE 164
+E A + H PGH PG C G +F+GD +F G YS+ + +
Sbjct: 111 -LVIEAAGADLTVLHTPGHAPGAVCLYDPGLGTVFTGDTLFQGGPGATGRSYSHFPTIID 169
Query: 165 SLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
S+ R + L P + E+ GHGD T+ AE H + W+ R
Sbjct: 170 SI-RDKLLVLPPETEVRTGHGDSTTIGAEAPHLEEWIKR 207
>ref|NP_143108.1| (NC_000961) hypothetical protein [Pyrococcus horikoshii]
pir||G71064 hypothetical protein PH1213 - Pyrococcus horikoshii
dbj|BAA30313.1| (AP000005) 223aa long hypothetical protein [Pyrococcus horikoshii]
Length = 223
Score = 60.1 bits (144), Expect = 2e-08
Identities = 52/185 (28%), Positives = 81/185 (43%), Gaps = 19/185 (10%)
Query: 12 EENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNT 71
+++ IV +G+ + G + E L + K+ I TH H+DHV + L+N
Sbjct: 29 KKSLLIVDTGTGVYWNKYLGIAEREGWLRDIKDV-IIFNTHEHFDHVGGNLIFKEKLRNV 87
Query: 72 PIYAPKDDVFMLEND------IFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGH 125
A + LE+ F+ G + + G + I N + H PGH
Sbjct: 88 KFAAQRLTAKALEDGDDYVILSFYYGRRYEPHDVELKLEDG-EKIRIGNIELTLLHTPGH 146
Query: 126 TPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI--- 180
T G C + E ++F+GD +F + GR D P +E M ES L+F KD ++
Sbjct: 147 TRGSSCLYYKEEKIMFTGDTVFAGTYGRTDLPTGDESKMIES------LEFLKDFDVRIG 200
Query: 181 YPGHG 185
PGHG
Sbjct: 201 LPGHG 205
>dbj|BAA34381.1| (AB019513) very similar to Mycobacterium tuberculosis hypothetical
protein Rv2260 [Streptomyces coelicolor]
Length = 209
Score = 60.1 bits (144), Expect = 2e-08
Identities = 47/159 (29%), Positives = 74/159 (45%), Gaps = 12/159 (7%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKG 106
AI+ TH H DHV +L++ T I+ +DD+ ++ P +P+ +
Sbjct: 59 AIVCTHAHNDHVDAAPRLAERTGAT-IWLHRDDL-----PLWQQTHPDRAPDAWLTDG-- 110
Query: 107 CTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKE 164
+E A + H PGH PG C G +F+GD +F G YS+ + +
Sbjct: 111 -LVIEAAGADLTVLHTPGHAPGAVCLYDPGLGTVFTGDTLFQGGPGATGRSYSHFPTIID 169
Query: 165 SLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
S+ R + L P + E+ GHGD T+ AE H + W+ R
Sbjct: 170 SI-RDKLLVLPPETEVRTGHGDSTTIGAEAPHLEEWIKR 207
>ref|NP_268890.1| (NC_002737) conserved hypothetical protein [Streptococcus pyogenes]
[Streptococcus pyogenes M1 GAS]
gb|AAK33611.1| (AE006518) conserved hypothetical protein [Streptococcus pyogenes
M1 GAS]
Length = 232
Score = 58.2 bits (139), Expect = 6e-08
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 14/194 (7%)
Query: 13 ENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPK---AILITHGHYDHVWDGAQLSKLLK 69
EN Y + + +IDPG + E + + K AIL+TH HYDH++ +
Sbjct: 34 ENTYYLVNDQAV-ILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFD 92
Query: 70 NTPIYAPKDDVFMLENDIFHL-GMPVFSPNFSVPCNKGCTTLEIAN----TTIKYWHFP- 123
+ P+Y + + L + +L G+ +V ++ ++ P
Sbjct: 93 HPPVYVSEKEAAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPT 152
Query: 124 -GHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
GH+ G + + ++ +GD +F +IGR D P SN +D+ +R + P +
Sbjct: 153 SGHSWGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITG-IRQELFTLPNHYRV 211
Query: 181 YPGHGDKTSFFAER 194
YPGHG T+ E+
Sbjct: 212 YPGHGPSTTICHEK 225
>ref|NP_216153.1| (NC_000962) hypothetical protein Rv1637c [Mycobacterium
tuberculosis H37Rv]
ref|NP_336129.1| (NC_002755) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
pir||C70560 hypothetical protein Rv1637c - Mycobacterium tuberculosis (strain
H37RV)
emb|CAB08907.1| (Z95554) hypothetical protein Rv1637c [Mycobacterium tuberculosis
H37Rv]
gb|AAK45943.1| (AE007031) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
Length = 264
Score = 57.4 bits (137), Expect = 1e-07
Identities = 54/212 (25%), Positives = 87/212 (40%), Gaps = 26/212 (12%)
Query: 3 ILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKN--PKAILI--THGHYDHV 58
IL+ G ++ NAY+V S+ + ++ + +E +++ + PK LI +H H+DH
Sbjct: 66 ILKASVGPMDNNAYLVTCSATGETLLIDAANDAEVLIDLVRRYAPKLALIVTSHQHFDH- 124
Query: 59 WDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIK 118
W Q P A D L PV + ++ I T
Sbjct: 125 WQALQAVAAATGAPTAAHPIDADPL---------PVKPDRLLTHGD----SVRIGELTFD 171
Query: 119 YWHFPGHTPGCSIIEIEGVI-------FSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
H GHTPG + + G + F+GD +F +G+ P + + + R +
Sbjct: 172 VIHLRGHTPGSIALALGGPVTGGVTQLFTGDCLFPGGVGKTWQPADFTQLLDDVTTRVFD 231
Query: 172 LDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
+ + IYPGHGD T AER W +R
Sbjct: 232 V-YADSTVIYPGHGDDTELGAERPSLSEWRAR 262
>ref|NP_126736.1| (NC_000868) HYDROXYACYLGLUTATHIONE HYDROLASE related (GLYOXALASE
II) [Pyrococcus abyssi]
pir||B75083 probable hydroxyacylglutathione hydrolase (EC 3.1.2.6) PAB0703
[imported] - Pyrococcus abyssi (strain Orsay)
emb|CAB49967.1| (AJ248286) HYDROXYACYLGLUTATHIONE HYDROLASE related (EC 3.1.2.6)
(GLYOXALASE II) [Pyrococcus abyssi]
Length = 222
Score = 57.4 bits (137), Expect = 1e-07
Identities = 56/204 (27%), Positives = 86/204 (41%), Gaps = 30/204 (14%)
Query: 3 ILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEW--VLENAKNP-------KAILI-TH 52
IL E ++ N Y +K + I+D G + W L+ A+N K I+ TH
Sbjct: 10 ILMLEGVNLDSNVYFLKSKDEL-LIVDTG-TGVYWNKYLDTARNEGWLENVSKVIIFNTH 67
Query: 53 GHYDHVWDGAQLSKLLKNTPIYAPK---------DDVFMLENDIFHLGMPVFSPNFSVPC 103
H+DHV + LK + K DD +L ++ G +
Sbjct: 68 EHFDHVGGNLVFKEKLKVVEFASHKLTAKALEEGDDYIILS---YYYGRRYDPHEVELKL 124
Query: 104 NKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKD 161
G +++ ++ H PGHT G C E E ++F+GD +F + GR D P NE
Sbjct: 125 EDG-DEIKVGKVKLRLIHTPGHTRGSSCLYYEEERIMFTGDTVFLGTYGRTDLPTGNEDK 183
Query: 162 MKESLLRFQNLDFPKDIEIYPGHG 185
+ ESL ++ D + PGHG
Sbjct: 184 IVESLELLKSFDVRLGL---PGHG 204
>ref|NP_336789.1| (NC_002755) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
gb|AAK46603.1| (AE007075) metallo-beta-lactamase superfamily protein
[Mycobacterium tuberculosis CDC1551]
Length = 212
Score = 57.0 bits (136), Expect = 1e-07
Identities = 44/163 (26%), Positives = 66/163 (39%), Gaps = 17/163 (10%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKG 106
A++ THGH DHV +L L + P D V + P+ S
Sbjct: 59 AVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR----------MTHPDKSFRAVSD 108
Query: 107 CTTLEIANTTIKYWHFPGHTPGC------SIIEIEGVIFSGDFIFYRSIGRYDFPYSNEK 160
+ + T ++ H PGH+PG + G +FSGD +F G YS+
Sbjct: 109 GDAVRVGGTELRALHTPGHSPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFP 168
Query: 161 DMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
+ S+ P D ++ GHGD T+ E H + WV+R
Sbjct: 169 TILRSISGRLGA-LPGDTVVHTGHGDSTTIGDEIVHYEEWVAR 210
>ref|NP_579030.1| (NC_003413) hypothetical protein [Pyrococcus furiosus DSM 3638]
gb|AAL81425.1| (AE010235) hypothetical protein [Pyrococcus furiosus DSM 3638]
Length = 228
Score = 57.0 bits (136), Expect = 1e-07
Identities = 47/157 (29%), Positives = 64/157 (39%), Gaps = 18/157 (11%)
Query: 43 KNPKAILI--THGHYDHVWDGAQLSKLLKNTPIYAP----KDDVFMLEND------IFHL 90
KN ++I TH H+DHV K K I KD LE +H
Sbjct: 56 KNISRVVIFNTHEHFDHVGGNHIFMKFFKEKGIEVEFASHKDTARTLEEGDDSIILSYHY 115
Query: 91 GMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFSGDFIFYRS 148
G + G L I + + H PGHT G C E E ++FSGD +F +
Sbjct: 116 GRKYEPHPVDIKLKDG-DLLSIGDVNLTVIHTPGHTQGSACLYYEDERIMFSGDTVFLNA 174
Query: 149 IGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
GR D P +E+++ SL R + + PGHG
Sbjct: 175 YGRTDLPTGDEEELIRSLERLARYEVRLGL---PGHG 208
>ref|NP_216776.1| (NC_000962) hypothetical protein Rv2260 [Mycobacterium tuberculosis
H37Rv]
pir||H70862 hypothetical protein Rv2260 - Mycobacterium tuberculosis (strain
H37RV)
emb|CAA17297.1| (AL021925) hypothetical protein Rv2260 [Mycobacterium tuberculosis
H37Rv]
Length = 211
Score = 57.0 bits (136), Expect = 1e-07
Identities = 44/163 (26%), Positives = 66/163 (39%), Gaps = 17/163 (10%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKG 106
A++ THGH DHV +L L + P D V + P+ S
Sbjct: 58 AVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWR----------MTHPDKSFRAVSD 107
Query: 107 CTTLEIANTTIKYWHFPGHTPGC------SIIEIEGVIFSGDFIFYRSIGRYDFPYSNEK 160
+ + T ++ H PGH+PG + G +FSGD +F G YS+
Sbjct: 108 GDAVRVGGTELRALHTPGHSPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFP 167
Query: 161 DMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
+ S+ P D ++ GHGD T+ E H + WV+R
Sbjct: 168 TILRSISGRLGA-LPGDTVVHTGHGDSTTIGDEIVHYEEWVAR 209
>ref|NP_247883.1| (NC_000909) conserved hypothetical protein [Methanococcus
jannaschii] [Methanocaldococcus jannaschii]
sp|Q58298|Y888_METJA Hypothetical protein MJ0888
pir||H64410 hypothetical protein homolog MJ0888 - Methanococcus jannaschii
gb|AAB98892.1| (U67532) conserved hypothetical protein [Methanococcus jannaschii]
[Methanocaldococcus jannaschii]
Length = 206
Score = 55.5 bits (132), Expect = 4e-07
Identities = 51/198 (25%), Positives = 88/198 (43%), Gaps = 21/198 (10%)
Query: 3 ILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVL------ENAKNPKAILITHGHYD 56
IL+ N+Y++ I +IDPG S + +L K+ I+ TH H+D
Sbjct: 2 ILKLNGYGYSSNSYLIIGKKNI--LIDPGTSGTFNILMEELERNGIKDIDLIINTHCHFD 59
Query: 57 HVWDGAQLSKLLKNTPIYAPKDDVFMLEN-------DIFHLGMPVFSPNFSVPCNKGCTT 109
H L + N P +V L+N +F G + P +P ++
Sbjct: 60 HT-SADYLIEEYFNCPTIIEDKEVKHLKNGDEVTVSSLF--GAKLNPPKEIIPLSE--IE 114
Query: 110 LEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRF 169
E+ + ++ PGHT G I E + +GD IF +GR+D P + ++ S+
Sbjct: 115 EELKSYGLEIIRTPGHTYGSISIIYENSLITGDTIFAYGVGRWDLPTGDVIQLRNSINLL 174
Query: 170 QNLDFPKDIE-IYPGHGD 186
+ + ++I+ +YPGHG+
Sbjct: 175 ERIANERNIDKLYPGHGE 192
>ref|NP_389590.1| (NC_000964) pksB [Bacillus subtilis]
pir||H69677 involved in polyketide synthesis pksB - Bacillus subtilis
emb|CAB13581.1| (Z99112) pksB [Bacillus subtilis]
emb|CAB13592.1| (Z99113) pksB [Bacillus subtilis]
Length = 225
Score = 54.3 bits (129), Expect = 8e-07
Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 17/173 (9%)
Query: 16 YIVK-LSSGIDFIIDPGFSSSE---WVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNT 71
YI++ + S ++DP + S+ + E KA+ +TH HYDHV L+K+ N
Sbjct: 22 YIIEDIVSRSAIVVDPSWELSKITTTLSELEAELKAVALTHSHYDHVNLVDPLTKMF-NA 80
Query: 72 PIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSI 131
+Y K ++ + +L S+ ++ T+ I NT + PGHT G
Sbjct: 81 QVYMSKKEIDYYQFRCRNL--------ISLDDHQ---TISIGNTRAQCLLTPGHTAGGMC 129
Query: 132 IEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
IF+GD +F G + S+ ++M +S+ R ++ + + +YPGH
Sbjct: 130 YLFSESIFTGDTVFTEGCGICEDDGSSAEEMFDSIQRIKS-EVSPHVRVYPGH 181
>ref|NP_539413.1| (NC_003317) HYDROXYACYLGLUTATHIONE HYDROLASE [Brucella melitensis]
gb|AAL51677.1| (AE009492) HYDROXYACYLGLUTATHIONE HYDROLASE [Brucella melitensis]
Length = 218
Score = 53.9 bits (128), Expect = 1e-06
Identities = 52/181 (28%), Positives = 77/181 (41%), Gaps = 18/181 (9%)
Query: 27 IIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFML 83
+IDPG + E + + +AI ITHGH DH L + L I +DD F+L
Sbjct: 31 VIDPGGDLARIREAIESQGIDVEAIWITHGHIDHAAAALDLKEALGVDIIGPHRDDKFLL 90
Query: 84 ENDI-------FHLGMPVFSPN-FSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIE 135
+N + G+ +P+ + +K C +A +H PGH PG +
Sbjct: 91 DNLVAAGLKYGITEGVRNVTPDQWLEEGDKVC----VAGHVFDVFHCPGHAPGHVVFFNP 146
Query: 136 GVIFS--GDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAE 193
F+ GD +F S+GR D P + + S+ + L DI GHG F E
Sbjct: 147 EARFAIVGDVLFNGSVGRTDLPGGDHATLIRSITE-KLLPLGDDIGFICGHGPGGRFGEE 205
Query: 194 R 194
R
Sbjct: 206 R 206
>ref|NP_355161.1| (NC_003062) AGR_C_4004p [Agrobacterium tumefaciens] [Agrobacterium
tumefaciens str. C58 (Cereon)]
ref|NP_532874.1| (NC_003304) hydrolase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
gb|AAK87946.1| (AE008136) AGR_C_4004p [Agrobacterium tumefaciens str. C58
(Cereon)]
gb|AAL43190.1| (AE009170) hydrolase [Agrobacterium tumefaciens str. C58 (U.
Washington)]
Length = 214
Score = 53.9 bits (128), Expect = 1e-06
Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 15/170 (8%)
Query: 27 IIDPGFSSS---EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFML 83
++DPG + V EN KAI +THGH DH +L + L + I + D +L
Sbjct: 31 VVDPGGDVDVILQVVAENGITLKAIWLTHGHLDHAGGADELREKLSLSVIGPHEHDRPLL 90
Query: 84 ENDIFHL------GMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGV 137
E G+ P+ + K + + + +H PGH PG I
Sbjct: 91 ERIEVQAQKYGISGLKNVEPDSWL---KDGDKVSFGDHVFEVYHCPGHAPGHVIYYNRDQ 147
Query: 138 IFS--GDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
F+ GD +F S+GR D P N + + S +R + L D+ GHG
Sbjct: 148 NFAHVGDVLFSGSVGRTDLPGGNHEQLMAS-IRDKLLPLGDDVGFICGHG 196
>gb|EAA09645.1| (AAAB01008904) ebiP940 [Anopheles gambiae str. PEST]
Length = 256
Score = 53.5 bits (127), Expect = 1e-06
Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 30/175 (17%)
Query: 24 IDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIY-----APKD 78
ID +++ ++ + E K L TH H DHV L +LL T K
Sbjct: 25 IDPVLEQAKRDAQLIKELGFTLKYALNTHMHADHVTGTGFLKQLLPGTVSVISQSSGAKA 84
Query: 79 DVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCS--IIEIEG 136
D +++N+ T++ ++ PGHT GC ++E +G
Sbjct: 85 DKHLVDNE----------------------TVQFGRHELRAMSTPGHTNGCMTFLVEEQG 122
Query: 137 VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFF 191
+ F+GD + R GR DF + + + S + + P++ ++P H K+S +
Sbjct: 123 IAFTGDTLLIRGCGRTDFQEGDSRSLYRS-VHERIFTLPENFRLFPAHDYKSSLW 176
>ref|NP_343464.1| (NC_002754) Conserved hypothetical protein [Sulfolobus
solfataricus]
pir||S73076 hypothetical protein c0601 - Sulfolobus solfataricus
emb|CAA69509.1| (Y08256) orf c06001 [Sulfolobus solfataricus]
gb|AAK42254.1| (AE006814) Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 247
Score = 52.8 bits (125), Expect = 2e-06
Identities = 48/176 (27%), Positives = 74/176 (41%), Gaps = 36/176 (20%)
Query: 26 FIIDPGFSSSEWVLENAKNP-----KAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDV 80
F++DP + + ++E A++ I+ TH H DH+ GA+ L N +Y
Sbjct: 28 FVVDPKYEMVDEIIELARDLGDMKIAYIIDTHTHADHL-SGAKKLASLTNANVY------ 80
Query: 81 FMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEI------ 134
+H + F V K ++ N IK H PGHTP + I
Sbjct: 81 -------YH---ELSQVKFKVERVKNGEEIKAGNVKIKVLHTPGHTPDSISVLIYDRRRD 130
Query: 135 -----EGVIFSGDFIFYRSIGRYDFPYSN-EKDMKESLLRFQNLDFPKDIEIYPGH 184
I +GD +F +GR D N E+++ SL + + L P +EIYP H
Sbjct: 131 ESWNEPWAILTGDTLFVGGLGRIDIGGENAEENLYYSLAKLKEL--PDYVEIYPAH 184
>ref|NP_577767.1| (NC_003413) glyoxalase II family member [Pyrococcus furiosus DSM
3638]
gb|AAL80162.1| (AE010130) glyoxalase II family member [Pyrococcus furiosus DSM
3638]
Length = 196
Score = 52.4 bits (124), Expect = 3e-06
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 25/181 (13%)
Query: 11 VEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKN 70
++ ++V + +GI+ + S + E K K I+ITH H DH + K
Sbjct: 15 IDRGDHLVLIDTGIEGTCEKILSK---IKELKKPLKTIIITHHHLDHT-GSLKCVKDATG 70
Query: 71 TPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG-- 128
+ A +++V ++E VP G +K +H PGHT G
Sbjct: 71 AKVVAHEEEVEVIEERT--------RVKVDVPVKDGDVI-----EGLKVFHMPGHTKGSI 117
Query: 129 CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDM---KESLLRFQNLDFPKDIEIYPGHG 185
C + E G +F GD + R Y+ P+ +D +E + N++F IYP HG
Sbjct: 118 CLLDEESGALFVGDIMIERDGKLYEVPHRYSEDPMMNRERIKDILNIEFKS---IYPAHG 174
Query: 186 D 186
+
Sbjct: 175 E 175
>ref|NP_301989.1| (NC_002677) conserved hypothetical protein [Mycobacterium leprae]
emb|CAC31772.1| (AL583921) conserved hypothetical protein [Mycobacterium leprae]
Length = 232
Score = 51.6 bits (122), Expect = 5e-06
Identities = 53/216 (24%), Positives = 87/216 (39%), Gaps = 30/216 (13%)
Query: 3 ILRRECGAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKN--PKAILI--THGHYDHV 58
IL+ G ++ NAY+V S+ + ++ + +E +++ + PK LI +H H+DH
Sbjct: 30 ILKVSVGPMDNNAYLVTCSATGETLLIDAANDAEVLIDLVQRYAPKLSLIVTSHQHFDH- 88
Query: 59 WDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIK 118
W + P + D L PV N C ++I T
Sbjct: 89 WQALEAVVAATGAPTAVHELDAEPL---------PVRPDRLLT--NGDC--VQIGELTFD 135
Query: 119 YWHFPGHTPGCSIIEIEGV-----------IFSGDFIFYRSIGRYDFPYSNEKDMKESLL 167
H GHTPG + ++G +F+GD +F +G+ + S+ + + +
Sbjct: 136 VIHLRGHTPGSIALALDGATSGPKTGRVTQLFTGDCLFPGGVGK-TWQRSDFTQLLDDVT 194
Query: 168 RFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
+ IYPGHGD T AER W R
Sbjct: 195 TRVFDVYADTTAIYPGHGDDTVLGAERPSLAEWRER 230
>ref|NP_103950.1| (NC_002678) probable hydrolase [Mesorhizobium loti]
dbj|BAB49736.1| (AP003000) probable hydrolase [Mesorhizobium loti]
Length = 212
Score = 51.2 bits (121), Expect = 7e-06
Identities = 48/182 (26%), Positives = 73/182 (39%), Gaps = 21/182 (11%)
Query: 27 IIDPGFSSSEWVL---ENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFML 83
++DPG + + +NA +AI ITHGH DH +L + L I D +L
Sbjct: 31 VVDPGGDIDKVLAVLKDNAITAEAIWITHGHIDHAGGAMELKEALCLDIIGPHAADKPLL 90
Query: 84 ENDIFHLGMPVFSPNFSVPCNKGCT---------TLEIANTTIKYWHFPGHTPGCSIIEI 134
+N + +S+ + C T+ + H PGH PG +
Sbjct: 91 DN------LEKQGRLYSIAGARNCVPDRFLTEGETVSFGGHVFEVLHCPGHAPGHVVYYN 144
Query: 135 EGVIFS--GDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFA 192
F+ GD +F S+GR D P + + S ++ + L DI GHG F
Sbjct: 145 RAAKFAHVGDVLFRGSVGRTDLPGGDHATLIAS-IKDKLLPLGDDIGFICGHGPGGRFGE 203
Query: 193 ER 194
ER
Sbjct: 204 ER 205
>ref|NP_142111.1| (NC_000961) hypothetical protein [Pyrococcus horikoshii]
pir||F71229 hypothetical protein PH0096 - Pyrococcus horikoshii
dbj|BAA29165.1| (AP000001) 198aa long hypothetical protein [Pyrococcus horikoshii]
Length = 198
Score = 51.2 bits (121), Expect = 7e-06
Identities = 52/183 (28%), Positives = 79/183 (42%), Gaps = 28/183 (15%)
Query: 14 NAYIVKLSSGIDFIIDPGFSSS-----EWVLENAKNPKAILITHGHYDHVWDGAQLSKLL 68
N YI+ + +ID G S+ + + E K K ++ITH H DH + K
Sbjct: 11 NVYIIDRGDHL-VLIDTGIESTCEKILKKIEELGKPLKTVIITHYHLDHT-GSLKCVKDG 68
Query: 69 KNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG 128
+ A +++V +E G+ V VP G +K +H PGHT G
Sbjct: 69 TGAKVVAHEEEVKAIEE---KTGVRV-----DVPVKDGDVV-----EGLKVFHMPGHTRG 115
Query: 129 --CSIIEIEGVIFSGDFIFYRSIGRYDFP--YSNEKDM-KESLLRFQNLDFPKDIEIYPG 183
C + E G +F GD + R Y+ P YS + M +E + N++F IYP
Sbjct: 116 SICLLDEESGALFVGDLMVERDGKLYEVPQQYSEDPMMNRERIKELLNIEFK---AIYPA 172
Query: 184 HGD 186
HG+
Sbjct: 173 HGE 175
>ref|NP_657766.1| (NC_003995) UPF0036, Uncharacterized protein family UPF0036
[Bacillus anthracis A2012] [Bacillus anthracis str.
A2012]
Length = 556
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPG--FSSSE------------WVLENAKNPKAILITHGH 54
G + +N Y V++ S I FI+D G F E +++EN + K + ITHGH
Sbjct: 18 GEIGKNMYCVEIDSEI-FIVDAGLMFPGDEMFGIDIVIPDITYLVENQERVKGLFITHGH 76
Query: 55 YDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIAN 114
DH+ + + L + P+YA K V +++ + GM ++ N +T+E
Sbjct: 77 EDHIGGIVYVLRKL-SIPVYATKLTVGLIQEKLGEAGMLGRVDLKTIDSN---STVEFNT 132
Query: 115 TTIKYW----HFPGHTPGCSIIEIEGVIFSGDFIF 145
TT+ ++ P C ++++GDF F
Sbjct: 133 TTVSFFGTTHSIPDSVGVCFHTSKGAIVYTGDFKF 167
>gb|AAF58646.2| (AE003826) CG30022-PA [Drosophila melanogaster]
Length = 279
Score = 49.3 bits (116), Expect = 3e-05
Identities = 50/188 (26%), Positives = 71/188 (37%), Gaps = 47/188 (25%)
Query: 17 IVKLSSGIDFIIDPGFSSSEWVLENAKNP-----------KAILITHGHYDHVWDGAQLS 65
+ L +G IIDP VLE AK K + TH H DH+ L
Sbjct: 65 LADLKNGQAVIIDP-------VLEQAKRDAQLVKDLGFELKYAINTHMHADHITGSGWLR 117
Query: 66 KLLKNTPIYAP----KDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWH 121
KL + A K D + E D G V +
Sbjct: 118 KLTGCQSVIAAASGAKADRHLNEGDRIDFGTHVIDALAT--------------------- 156
Query: 122 FPGHTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIE 179
PGHT GC +I+ +G +F+GD + R GR DF +++ E+ + + P++
Sbjct: 157 -PGHTNGCMTYVIKDQGCVFTGDTLLIRGCGRTDFQEGCPRNLYEN-VHSKIFTLPENFR 214
Query: 180 IYPGHGDK 187
IYP H K
Sbjct: 215 IYPAHDYK 222
>gb|AAH04749.1|AAH04749 (BC004749) Similar to hydroxyacyl glutathione hydrolase [Mus
musculus]
gb|AAH19817.1| (BC019817) Unknown (protein for MGC:29966) [Mus musculus]
Length = 260
Score = 49.3 bits (116), Expect = 3e-05
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 33/169 (19%)
Query: 27 IIDPGFSSSEWVLENAKNPKA----ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
I+DP + V+E AK +L TH H+DH +L KL +Y D +
Sbjct: 27 IVDP--VQPQKVIEAAKKHHVKLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGA 84
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEG---- 136
L + + HL +TL++ + ++K P HT G C + G
Sbjct: 85 LTHKVTHL-----------------STLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEP 127
Query: 137 -VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
+F+GD +F G+ F +M ++LL P D ++Y GH
Sbjct: 128 SAVFTGDTLFVAGCGK--FYEGTADEMYKALLEVLG-RLPPDTKVYCGH 173
>ref|NP_616720.1| (NC_003552) metallo-beta-lactamase [Methanosarcina acetivorans str.
C2A] [Methanosarcina acetivorans C2A]
gb|AAM05200.1| (AE010859) metallo-beta-lactamase [Methanosarcina acetivorans str.
C2A] [Methanosarcina acetivorans C2A]
Length = 481
Score = 48.9 bits (115), Expect = 4e-05
Identities = 43/150 (28%), Positives = 61/150 (40%), Gaps = 28/150 (18%)
Query: 48 ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGC 107
IL TH H D V L++L PIYAP+ E H+G+
Sbjct: 50 ILETHLHADFVSGHMDLAELT-GAPIYAPEAAKCEFE----HVGLVEGD----------- 93
Query: 108 TTLEIANTTIKYWHFPGHTPGCSIIEIEG--------VIFSGDFIFYRSIGRYDFPYSNE 159
T EI + T+K PGHTP + +F GD +F +GR D
Sbjct: 94 -TFEIEDMTVKVLETPGHTPEHISYVVSDTSRGPDPTAVFCGDTLFVGDVGRPDLFPGKA 152
Query: 160 KDMKESL---LRFQNLDFPKDIEIYPGHGD 186
+++ +L L + L P E+YP HG+
Sbjct: 153 RELASTLYDSLHKKLLSLPDSCEVYPAHGE 182
>ref|NP_231867.1| (NC_002505) hydroxyacylglutathione hydrolase GloB, putative [Vibrio
cholerae]
pir||A82102 probable hydroxyacylglutathione hydrolase GloB VC2236 [imported] -
Vibrio cholerae (group O1 strain N16961)
gb|AAF95380.1| (AE004295) hydroxyacylglutathione hydrolase GloB, putative [Vibrio
cholerae]
Length = 252
Score = 48.9 bits (115), Expect = 4e-05
Identities = 47/162 (29%), Positives = 71/162 (43%), Gaps = 26/162 (16%)
Query: 27 IIDPGFSSSEWVLENAK----NPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
++DPG S+E VL K N KA+LITH H+DH+ A+L + P +
Sbjct: 27 VVDPG--SAEPVLAYLKQHDLNLKAVLITHHHHDHIGGVAELVHQFPEIHVVGPAQE--- 81
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGD 142
P+ P + P G +E+ + PGHT G +G +F GD
Sbjct: 82 ----------PI--PTLTHPVEDG-DQIELFDERFMVLGLPGHTLGHIGYVGDGKLFCGD 128
Query: 143 FIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
+F GR F + E+ M SL + L P++ ++Y H
Sbjct: 129 VLFSAGCGRV-FEGTMEQ-MFSSLNKL--LSLPEETQVYSAH 166
>ref|NP_111449.1| (NC_002689) Zn-dependent hydrolase [Thermoplasma volcanium]
dbj|BAB60100.1| (AP000994) hypothetical protein [Thermoplasma volcanium]
Length = 312
Score = 48.9 bits (115), Expect = 4e-05
Identities = 55/208 (26%), Positives = 90/208 (42%), Gaps = 40/208 (19%)
Query: 14 NAYIVKLSSGIDFIIDPGFS--SSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNT 71
N Y V G +ID G S S + +++ + + +A+ +TH H DHV ++ + L
Sbjct: 21 NIYRVPSDKGY-ILIDTGMSGDSVDQIVKESNDIQAVFLTHLHIDHVGGALRIHEEL-GV 78
Query: 72 PIYAPKDDVFMLEN-------------DIFH-LGMPVFSP----------NFSVPCNKGC 107
P+Y D+ ++ DIF G+P+ NF +K
Sbjct: 79 PVYMNSKDINLIRQVANDKEAYIKKYVDIFRGNGVPLSMQEDLIHMHPVINFYEYYSKLG 138
Query: 108 TTLEIANTTIKYWHF---PGHTPGCSIIEIEG--VIFSGDFIFYRSIGRYDFPYSNEKDM 162
+I+N +K F PGH+PG + + E ++FSGD I R Y E D+
Sbjct: 139 FLQDISNLKLKELKFVPVPGHSPGSTAVITEDGYMMFSGDHILERITPNISV-YGEEDDL 197
Query: 163 KESLLRFQNLDFPKDIE---IYPGHGDK 187
L ++L+ K + I+PGHG +
Sbjct: 198 GNYL---KSLELVKKLSPKIIFPGHGSR 222
>ref|NP_045994.1| (NC_001869) ORF H0571 [Halobacterium sp. NRC-1]
ref|NP_046105.1| (NC_001869) ORF H1786 [Halobacterium sp. NRC-1]
ref|NP_395620.1| (NC_002608) Vng6066c [Halobacterium sp. NRC-1]
ref|NP_395918.1| (NC_002608) Vng6460c [Halobacterium sp. NRC-1]
pir||T08266 conserved hypothetical protein H0571 - Halobacterium sp. (strain
NRC-1) plasmid pNRC100
gb|AAC82833.1| (AF016485) ORF H0571 [Halobacterium sp. NRC-1]
gb|AAC82944.1| (AF016485) ORF H1786 [Halobacterium sp. NRC-1]
gb|AAG20755.1| (AE005144) Vng6066c [Halobacterium sp. NRC-1]
gb|AAG21053.1| (AE005170) Vng6460c [Halobacterium sp. NRC-1]
Length = 369
Score = 48.5 bits (114), Expect = 5e-05
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 33/181 (18%)
Query: 18 VKLSSGIDFIIDPGFSSSEW---VLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIY 74
V +S G + DP +E+ + E + TH H DHV A L+ + P Y
Sbjct: 132 VLVSDGEAAVFDPSHYLNEYDTVLDEYDAELVGVFDTHAHADHVSGAADLADR-HDVPYY 190
Query: 75 APKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEI 134
+ D ++ + P G T+ + I+ H PGH+ G ++
Sbjct: 191 LHQKDALAVD---------------ATPLEDG-QTVTVGRLDIEVIHTPGHSEGSVSFDV 234
Query: 135 EG-VIFSGDFIFYRSIGRYDFPY----------SNEKDMKESLLRFQNLDFPKDIEIYPG 183
EG + +GD +F+ S+GR + N + ESL R LD P D + P
Sbjct: 235 EGAALLTGDTLFHDSVGRVELGVEAGIEDADVEGNAATLYESLQRL--LDRPDDALVLPA 292
Query: 184 H 184
H
Sbjct: 293 H 293
>ref|NP_377601.1| (NC_003106) 246aa long conserved hypothetical protein [Sulfolobus
tokodaii]
dbj|BAB66710.1| (AP000987) 246aa long conserved hypothetical protein [Sulfolobus
tokodaii]
Length = 246
Score = 48.1 bits (113), Expect = 6e-05
Identities = 45/176 (25%), Positives = 73/176 (40%), Gaps = 36/176 (20%)
Query: 26 FIIDPGFSSSEWVLENAKNP-----KAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDV 80
F+IDP + +++ A++ I+ TH H DH+ GA+ + L N +Y ++
Sbjct: 27 FVIDPKYEHINEIIKLAEDLGDMKIAYIIDTHTHADHI-SGARKLQSLTNANVYYHEES- 84
Query: 81 FMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEI------ 134
+F V K ++ N IK H PGHTP I I
Sbjct: 85 ---------------KVSFQVERLKDGEEIKAGNVKIKIIHTPGHTPDSISILIYDRRRD 129
Query: 135 -----EGVIFSGDFIFYRSIGRYDFPYSNEKD-MKESLLRFQNLDFPKDIEIYPGH 184
+ +GD +F ++GR D + + + SL + + L P +EIYP H
Sbjct: 130 ESWSEPWAVLTGDTLFVGTVGRIDIGGEDSAEKLYYSLSKLKEL--PDYVEIYPAH 183
>ref|NP_600531.1| (NC_003450) COG0491:Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum]
dbj|BAB98703.1| (AP005278) Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum ATCC 13032]
Length = 469
Score = 47.8 bits (112), Expect = 8e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 19/96 (19%)
Query: 108 TTLEIANTTIKYWHFPGHTP--------GCSIIEIEGVIFSGDFIFYRSIGR-------- 151
+T+++ N TI H PGHTP ++ + G + SGDF+F +GR
Sbjct: 99 STIKLGNITITAKHTPGHTPEHLSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAA 158
Query: 152 --YDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
D ++ + + S L+ Q L P I++YPGHG
Sbjct: 159 GGVDTRFAGAQQLFHS-LKEQFLALPDHIQVYPGHG 193
>ref|NP_203500.1| (NM_033349) hydroxyacyl glutathione hydrolase; glyoxalase II; round
spermatid protein RSP29 [Rattus norvegicus]
sp|O35952|GLO2_RAT Hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) (Round
spermatid protein RSP29)
pir||JC5826 hydroxyacylglutathione hydrolase (EC 3.1.2.6) - rat
gb|AAC39944.1| (U97667) RSP29 [Rattus norvegicus]
Length = 260
Score = 47.4 bits (111), Expect = 1e-04
Identities = 42/169 (24%), Positives = 69/169 (39%), Gaps = 33/169 (19%)
Query: 27 IIDPGFSSSEWVLENAKNPKA----ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
++DP + V+E K + +L TH H+DH +L KL +Y D +
Sbjct: 27 VVDP--VQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGA 84
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEG---- 136
L + + HL +TLE+ + ++K P HT G C + G
Sbjct: 85 LTHKVTHL-----------------STLEVGSLSVKCLSTPCHTSGHICYFVSKPGSSEP 127
Query: 137 -VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
+F+GD +F G+ F +M ++LL P D ++ GH
Sbjct: 128 SAVFTGDTLFVAGCGK--FYEGTADEMYKALLEVLG-RLPPDTKVICGH 173
>ref|NP_005317.1| (NM_005326) hydroxyacyl glutathione hydrolase; hydroxyacyl
glutathione hydrolase; glyoxalase 2; Hydroxyacyl
glutathione hydrolase; glyoxalase II;
hydroxyacylglutathione hydroxylase [Homo sapiens]
sp|Q16775|GLO2_HUMAN Hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II)
pdb|1QH5|A Chain A, Human Glyoxalase Ii With S-(N-Hydroxy-N-
Bromophenylcarbamoyl)glutathione
pdb|1QH5|B Chain B, Human Glyoxalase Ii With S-(N-Hydroxy-N-
Bromophenylcarbamoyl)glutathione
pdb|1QH3|A Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions
Present In The Active Site
pdb|1QH3|B Chain B, Human Glyoxalase Ii With Cacodylate And Acetate Ions
Present In The Active Site
emb|CAA62483.1| (X90999) glyoxalase II [Homo sapiens]
emb|CAC14021.1| (AL031722) C429E7.1 (hydroxyacyl glutathione hydrolase) [Homo
sapiens]
gb|AAH00840.1|AAH00840 (BC000840) hydroxyacyl glutathione hydrolase [Homo sapiens]
gb|AAH02627.1|AAH02627 (BC002627) hydroxyacyl glutathione hydrolase [Homo sapiens]
gb|AAK61294.1|AE006639_8 (AE006639) hydroxyacylglutathione hydrolase [Homo sapiens]
Length = 260
Score = 47.4 bits (111), Expect = 1e-04
Identities = 38/144 (26%), Positives = 58/144 (39%), Gaps = 27/144 (18%)
Query: 48 ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGC 107
+L TH H+DH +L KL +Y D + L + I HL
Sbjct: 50 VLTTHHHWDHAGGNEKLVKLESGLKVYGGDDRIGALTHKITHL----------------- 92
Query: 108 TTLEIANTTIKYWHFPGHTPG--CSIIEIEG-----VIFSGDFIFYRSIGRYDFPYSNEK 160
+TL++ + +K P HT G C + G +F+GD +F G+ F
Sbjct: 93 STLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGK--FYEGTAD 150
Query: 161 DMKESLLRFQNLDFPKDIEIYPGH 184
+M ++LL P D +Y GH
Sbjct: 151 EMCKALLEVLG-RLPPDTRVYCGH 173
>ref|NP_633310.1| (NC_003901) hypothetical protein [Methanosarcina mazei Goe1]
gb|AAM30982.1| (AE013360) hypothetical protein [Methanosarcina mazei Goe1]
Length = 213
Score = 47.0 bits (110), Expect = 1e-04
Identities = 49/176 (27%), Positives = 77/176 (42%), Gaps = 20/176 (11%)
Query: 27 IIDPGFSSSEWVLENAK-----NPKAILITHGHYDHVWDGAQLS-KLLKNTPIYAPK--- 77
+ID G +S + + K K I++TH HYDH A ++ K I+
Sbjct: 23 LIDAGMNSDLIIKQLEKYIKLTELKLIILTHCHYDHTAAAAAIAEKSGAEVGIHKADLEG 82
Query: 78 -DDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIAN-TTIKYWHFPGHTPG--CSIIE 133
+D ++ + +F P P ++ +G ++I + +K H PGH+ G C
Sbjct: 83 VNDEYLSVSVLFGERAPAVKP--TITYEEG-DKIDIGDGEYLKVIHTPGHSKGSICLYEP 139
Query: 134 IEGVIFSGDFIFYR-SIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKT 188
+ +FSGD +F R GR DF S M S+ + LD +Y GHG T
Sbjct: 140 VSKSLFSGDTVFPRGGFGRMDFEGSEPNKMLGSVEKLTKLDVK---NLYSGHGAPT 192
>ref|NP_619473.1| (NC_003552) metallo-beta-lactamase [Methanosarcina acetivorans str.
C2A] [Methanosarcina acetivorans C2A]
gb|AAM07953.1| (AE011184) metallo-beta-lactamase [Methanosarcina acetivorans str.
C2A] [Methanosarcina acetivorans C2A]
Length = 213
Score = 47.0 bits (110), Expect = 1e-04
Identities = 49/173 (28%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 27 IIDPGFSSSEWVLENAKNPKA-----ILITHGHYDHVWDGAQL-----SKLLKNTPIYAP 76
+ID G SS + E K+ K I++TH HYDH A++ +K+ +
Sbjct: 23 LIDAGMSSDLIIRELEKSIKLTDLELIILTHCHYDHTAAAAEIAEKSGAKVGIHRADLEG 82
Query: 77 KDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTT-IKYWHFPGHTPG--CSIIE 133
+D ++ + +F P P +V +G + I N ++ H PGH+ G C
Sbjct: 83 VNDEYLSVSVLFGDRAPAVKP--TVIYEEG-DRIPIGNEEFLEVIHTPGHSKGSICLYEP 139
Query: 134 IEGVIFSGDFIF-YRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
+ +FSGD +F GR DF S + M S+ + LD +Y GHG
Sbjct: 140 VSKSLFSGDTVFPGGGFGRMDFEGSEPEKMLGSVEKLTKLDVK---NLYSGHG 189
>sp|Q28333|GLO2_CALJA Hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) (Germ
cell specific protein)
emb|CAA64612.1| (X95294) ORF [Callithrix jacchus]
Length = 260
Score = 47.0 bits (110), Expect = 1e-04
Identities = 45/169 (26%), Positives = 68/169 (39%), Gaps = 33/169 (19%)
Query: 27 IIDPGFSSSEWVLENAKNP----KAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
I+DP + V+E AK +L TH H+DH +L KL +Y D +
Sbjct: 27 IVDP--VQPQKVVEEAKKHGVMLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGG 84
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEG---- 136
L + HL +TL++ + +K P HT G C + G
Sbjct: 85 LTHKGTHL-----------------STLQVGSLNVKCLSTPCHTSGHICYFVTKPGGSQP 127
Query: 137 -VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
+F+GD +F G+ F +M ++LL FP D +Y GH
Sbjct: 128 PAVFTGDTLFVAGCGK--FYEGTADEMCKALLEVLG-RFPPDTRVYCGH 173
>ref|NP_641426.1| (NC_003919) hydroxyacylglutathione hydrolase [Xanthomonas
axonopodis pv. citri str. 306]
gb|AAM35962.1| (AE011738) hydroxyacylglutathione hydrolase [Xanthomonas axonopodis
pv. citri str. 306]
Length = 255
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 22/135 (16%)
Query: 21 SSGIDFIIDPGFSSSEWVLENAKN----PKAILITHGHYDHVWDGAQLSKLLKNTPIYAP 76
+ G I+DPG +E VL A+ P A+L+TH H DH+ A+L + + ++ P
Sbjct: 20 ADGRAIIVDPG--QAEPVLAAAQRQGLVPSAVLLTHHHGDHIGGVAELQQRWPDLALFGP 77
Query: 77 KDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEG 136
D+ + + H+G + L++ IK PGHT +G
Sbjct: 78 ADE--RIPTNAHHVGR-----------GERLRLLDVEFQVIK---VPGHTRSHIAFLADG 121
Query: 137 VIFSGDFIFYRSIGR 151
+FSGD +F GR
Sbjct: 122 HLFSGDTLFSLGCGR 136
>ref|NP_249523.1| (NC_002516) conserved hypothetical protein [Pseudomonas aeruginosa]
pir||H83540 conserved hypothetical protein PA0832 [imported] - Pseudomonas
aeruginosa (strain PAO1)
gb|AAG04221.1|AE004518_2 (AE004518) conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 213
Score = 46.6 bits (109), Expect = 2e-04
Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)
Query: 27 IIDPGFSSSEWVLENAKN----PKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
++DPG E +L+ +I+ TH H DH ++ K ++ KDD F+
Sbjct: 34 VVDPG-GDHELILQRLDRLGLQVVSIIHTHAHLDHFLASGEMKKRT-GASLHLHKDDQFL 91
Query: 83 ---LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEI--EGV 137
LE G+P ++P P E+A H PGHTPG +
Sbjct: 92 WDNLEMQCQLFGVP-YTP-VPAPDRWLADDEELACGCGVALHTPGHTPGSMSFWFPRAKL 149
Query: 138 IFSGDFIFYRSIGRYDFPYSNEKDMKESL-LRFQNLDFPKDIEIYPGHGDKTSFFAE 193
+ +GD +F R IGR D + ++ S+ R +LD +D + GHG T+ E
Sbjct: 150 LIAGDTLFRRGIGRTDLWGGDSAAIQRSIRQRLYSLD--EDATVVAGHGPDTTLGEE 204
>ref|NP_626224.1| (NC_003888) putative hydrolase [Streptomyces coelicolor A3(2)]
pir||T36033 probable hydrolase - Streptomyces coelicolor
emb|CAB38150.1| (AL035591) putative hydrolase [Streptomyces coelicolor A3(2)]
Length = 218
Score = 46.6 bits (109), Expect = 2e-04
Identities = 48/208 (23%), Positives = 85/208 (40%), Gaps = 33/208 (15%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLENAKNP--KAILITHGHYDHVWDGAQLSK 66
G + NAY+++ + + ++ + + +L + +++ TH H DH W
Sbjct: 29 GPMNNNAYLLRCRATDEQLLIDAANDAHTLLGTIGDDGIASVVTTHRHGDH-WQALAEVV 87
Query: 67 LLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHT 126
+A + D G+PV + V + G T+ + + H GHT
Sbjct: 88 AATGARTHAGRHDAE---------GIPVPT---DVLIDDG-DTIRVGQVELTARHIAGHT 134
Query: 127 PGCSIIEIEGV-----IFSGDFIFYRSIGRYDFPYSNEKDMKESLLR------FQNLDFP 175
PG ++ + +F+GD +F +G + D SL+ F L P
Sbjct: 135 PGSVVLVYDDPHGHPHVFTGDCLFPGGVGNT----FKDPDAFASLIHDVQTKVFDTL--P 188
Query: 176 KDIEIYPGHGDKTSFFAEREHSKIWVSR 203
+ +YPGHG+ T+ AER H W +R
Sbjct: 189 DETWVYPGHGNDTTLGAERPHLPEWRAR 216
>ref|NP_600593.1| (NC_003450) COG0491:Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum]
dbj|BAB98768.1| (AP005278) Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum ATCC 13032]
Length = 200
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/165 (29%), Positives = 72/165 (43%), Gaps = 29/165 (17%)
Query: 48 ILITHGHYDHVWDGAQLSKLLKNTPI--YAPKDDVFMLENDIFHLGMPVFSPNFSVPCNK 105
+L TH H DHV L ++L+ T YAP L +P V +
Sbjct: 54 VLTTHRHADHV---RALPEVLQKTGATHYAP------------FLEVPALPSAVDVELHH 98
Query: 106 GCTTLEIANTTIKYWHFPGHTPGCSII--EIEGV--IFSGDFIFYRSIGRYDFPYSNEK- 160
G ++E GHTPG +++ EI+G +F GD +F +G+ +
Sbjct: 99 G-DSIEFEGHVFPISILRGHTPGGAVLTAEIDGKTHLFVGDSLFPGGLGKTSSEGDFVRL 157
Query: 161 --DMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAEREHSKIWVSR 203
D+KE + F D D ++PGHG +T+ AER +IW R
Sbjct: 158 FNDVKERI--FDTYD--DDSIVWPGHGKETTLGAERPQLEIWWER 198
>dbj|BAB83478.1| (AB063171) ORF2 [Staphylococcus hominis]
Length = 442
Score = 45.8 bits (107), Expect = 3e-04
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 17/91 (18%)
Query: 112 IANTTIKYWHFPGHTPGCS--IIEIEGV-------IFSGDFIFYRSIGRYDF-------P 155
+ N +K H PGHTP ++ EG +FSGDFIF IGR D
Sbjct: 106 VGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVE 165
Query: 156 YSNEKDMKESLLRFQNL-DFPKDIEIYPGHG 185
S+E K+ +++ D P I+I+PGHG
Sbjct: 166 GSSEIGAKQMFKSIESIKDLPDYIQIWPGHG 196
>dbj|BAA86645.1| (AB033763) hypothetical protein [Staphylococcus aureus]
Length = 442
Score = 45.8 bits (107), Expect = 3e-04
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 17/91 (18%)
Query: 112 IANTTIKYWHFPGHTPGCS--IIEIEGV-------IFSGDFIFYRSIGRYDF-------P 155
+ N +K H PGHTP ++ EG +FSGDFIF IGR D
Sbjct: 106 VGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVE 165
Query: 156 YSNEKDMKESLLRFQNL-DFPKDIEIYPGHG 185
S+E K+ +++ D P I+I+PGHG
Sbjct: 166 GSSEIGAKQMFKSIESIKDLPDYIQIWPGHG 196
>ref|NP_391950.1| (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
sp|P37502|YYBB_BACSU Hypothetical protein yybB
pir||S65995 conserved hypothetical protein yybB - Bacillus subtilis
dbj|BAA05201.1| (D26185) unknown [Bacillus subtilis]
emb|CAB16107.1| (Z99124) similar to hypothetical proteins [Bacillus subtilis]
Length = 220
Score = 45.8 bits (107), Expect = 3e-04
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 17/159 (10%)
Query: 44 NPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPC 103
NPKAIL+THGH DH+ GA SK L+ I +F + ++ ++ PN +
Sbjct: 59 NPKAILLTHGHSDHI-GGA--SKWLERFDI-----PIFAHQKELKYINGEEPYPNKNEVE 110
Query: 104 NKG-------CTTLEIANTTIKYWHFPGHTPGCSII--EIEGVIFSGDFIFYRSIGRYDF 154
N G T +A+ +KY+ PGH+PG + +I+ + +GD +
Sbjct: 111 NTGVAHIVQPLTEQTLAHLPLKYYLTPGHSPGHVVYYHKIDRTLLTGDLFITSKEDLHPP 170
Query: 155 PYSNEKDMKESLLRFQNLDFPKDIEIYPGHGDKTSFFAE 193
D+ E++ +D K I HG++ + E
Sbjct: 171 IRRFSVDINENIDSGSIIDQIKPTLICSSHGEEILYNEE 209
>ref|NP_660586.1| (NC_004061) probable hydroxyacylglutathione hydrolase [Buchnera
aphidicola str. Sg (Schizaphis graminum)]
sp|Q08889|GLO2_BUCAP Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II)
pir||I40592 hypothetical protein 1 - Buchnera aphidicola
gb|AAA17433.1| (L18927) ORF1 [Buchnera aphidicola]
gb|AAM67797.1| (AE014100) probable hydroxyacylglutathione hydrolase [Buchnera
aphidicola str. Sg (Schizaphis graminum)]
Length = 250
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 18/127 (14%)
Query: 27 IIDPGFSSSEWVLENAKNPK--AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLE 84
IIDPG S KN K AIL+TH H DHV ++ + N ++ P++
Sbjct: 26 IIDPGVSEDIIKKIEKKNWKLIAILLTHNHIDHVGGVEEIIRRYPNVTVFGPEETKTRNV 85
Query: 85 NDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFI 144
N I G +++ + I + PGHT G ++ IF GD +
Sbjct: 86 NKIVKQG----------------DVIKLLKSEIHVFLTPGHTLGHVSYYLKPYIFCGDTL 129
Query: 145 FYRSIGR 151
F GR
Sbjct: 130 FSGGCGR 136
>ref|NP_370611.1| (NC_002758) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus Mu50]
ref|NP_373324.1| (NC_002745) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus N315]
ref|NP_644872.1| (NC_003923) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus MW2]
dbj|BAB41302.1| (AP003129) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus N315]
dbj|BAB56249.1| (AP003358) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus Mu50]
dbj|BAB93922.1| (AP004822) conserved hypothetical protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 444
Score = 45.4 bits (106), Expect = 4e-04
Identities = 30/95 (31%), Positives = 44/95 (45%), Gaps = 21/95 (22%)
Query: 110 LEIANTTIKYWHFPGHTPGCSIIEIEGV---------IFSGDFIFYRSIGRYDF------ 154
+++ N ++ H PGHTP + + +FSGDFIF IGR D
Sbjct: 104 IQVGNVKLEVLHTPGHTPESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQ 163
Query: 155 ----PYSNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
+ K M ES+ +NL P ++I+PGHG
Sbjct: 164 IKGSTEISAKQMYESVQNIKNL--PDYVQIWPGHG 196
>ref|NP_421662.1| (NC_002696) metallo-beta-lactamase family protein [Caulobacter
crescentus CB15]
gb|AAK24830.1| (AE005951) metallo-beta-lactamase family protein [Caulobacter
crescentus CB15]
Length = 267
Score = 45.4 bits (106), Expect = 4e-04
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query: 48 ILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPN-------FS 100
+L TH H DH+ A L + I + ++ +PVF + F
Sbjct: 47 VLETHAHADHL-SAADLIRRKTGAKIV-----IGAKITEVQKTFIPVFESDARPDGAVFD 100
Query: 101 VPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIG--RYDFPYSN 158
V +G L + +I H PGHTP C I F GD +F G R DFP +
Sbjct: 101 VLMEEG-DALPLGELSIAALHTPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGD 159
Query: 159 EKDMKESLLRFQNLDFPKDIEIYPGH 184
+ + S+ + L P + I+ GH
Sbjct: 160 ARTLYRSIQKV--LALPDETRIFVGH 183
>ref|NP_243264.1| (NC_002570) BH2398~unknown conserved protein [Bacillus halodurans]
dbj|BAB06117.1| (AP001515) BH2398~unknown conserved protein [Bacillus halodurans]
Length = 555
Score = 45.4 bits (106), Expect = 4e-04
Identities = 39/155 (25%), Positives = 75/155 (48%), Gaps = 23/155 (14%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPG--FSSSE------------WVLENAKNPKAILITHGH 54
G + +N Y+V++ + F+ID G F E +++EN + +AIL+THGH
Sbjct: 18 GEIGKNMYVVEVDDDL-FVIDAGLMFPDDEMLGVDVVIPDISYLVENEERVRAILLTHGH 76
Query: 55 YDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIAN 114
DH+ + + L N P+Y K + ++E + G+ + + N + L++ +
Sbjct: 77 EDHIGGLPYVLQKL-NVPVYGTKLTLGLVEEKLKEAGLIRSAKLKLIDSN---SRLKLGS 132
Query: 115 TTIKYW---HFPGHTPGCSIIEIEG-VIFSGDFIF 145
T + ++ H + G I +G ++ +GDF F
Sbjct: 133 TPVSFFRTNHSIPDSVGICIQTSQGFIVHTGDFKF 167
>ref|NP_404693.1| (NC_003143) putative hydroxyacylglutathione hydrolase [Yersinia
pestis]
emb|CAC89922.1| (AJ414146) putative hydroxyacylglutathione hydrolase [Yersinia
pestis]
Length = 251
Score = 45.1 bits (105), Expect = 5e-04
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 27 IIDPGFSSS--EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLE 84
I+DPG S+ + + P+AIL+TH H DHV A L + P+Y P++
Sbjct: 26 IVDPGESAPVLATLAQGQYVPQAILLTHHHNDHVGGVADLRHHFPDIPVYGPQETA---- 81
Query: 85 NDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFI 144
+V N G +L IA PGHT G +F GD +
Sbjct: 82 -----------KKGATVIVNDG-DSLTIAGQNYTIIAVPGHTLGHIAYYSSPYLFCGDTL 129
Query: 145 FYRSIGR 151
F GR
Sbjct: 130 FSAGCGR 136
>ref|NP_064383.1| (NM_019999) brain protein 17 [Mus musculus]
dbj|BAA95092.1| (AB041609) unnamed protein product [Mus musculus]
Length = 360
Score = 44.7 bits (104), Expect = 7e-04
Identities = 49/209 (23%), Positives = 83/209 (39%), Gaps = 45/209 (21%)
Query: 17 IVKLSSGIDFIIDPGFSSSEW--VLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIY 74
I+ +G+ +DP + + + N AIL TH H+DH LS+ ++ +Y
Sbjct: 110 IIDTQAGLAVAVDPSDPRAVQASIEKERVNLVAILCTHKHWDHSGGNRDLSRRHRDCRVY 169
Query: 75 -APKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIE 133
+P+D + L + + H + + + I+ PGHT G +
Sbjct: 170 GSPQDGIPYLTHPLCHQDV-----------------VSVGRLQIRALATPGHTQGHLVYL 212
Query: 134 IEG-------VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN--LDFPKDIEIYPGH 184
++G +FSGD +F GR + E++L + LD D ++PGH
Sbjct: 213 LDGEPYKGPSCLFSGDLLFLSGCGR------TFEGTAETMLSSLDTVLDLGDDTLLWPGH 266
Query: 185 --GDKTSFFA--------EREHSKIWVSR 203
++ FA RE WV R
Sbjct: 267 EYAEENLGFAGVVEPENLARERKMQWVQR 295
>ref|NP_644860.1| (NC_003923) hypothetical protein [Staphylococcus aureus subsp.
aureus MW2]
dbj|BAB72102.1| (AB063172) hypothetical protein [Staphylococcus aureus]
dbj|BAB93910.1| (AP004822) hypothetical protein [Staphylococcus aureus subsp.
aureus MW2]
Length = 334
Score = 44.7 bits (104), Expect = 7e-04
Identities = 48/182 (26%), Positives = 74/182 (40%), Gaps = 36/182 (19%)
Query: 27 IIDPGFSSSEWVLENAKNPKAILITHGHYDHVW----DGAQLSKLLKNTPIYAP--KDDV 80
IIDP S ++ + +++ ITH H+ G + + N IY DD+
Sbjct: 2 IIDPICDLSSYI--RVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDM 59
Query: 81 FMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCS--IIEIEGV- 137
+N H + + + + N +K H PGHTP ++ EG
Sbjct: 60 LGYKNMPNHTHFVQHNDD-----------IYVGNIKLKVLHTPGHTPESISFLLTDEGAG 108
Query: 138 ------IFSGDFIFYRSIGRYDFPYS-------NEKDMKESLLRFQNL-DFPKDIEIYPG 183
+FSGDFIF IGR D +E K+ +++ D P I+I+PG
Sbjct: 109 AQVPMGLFSGDFIFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLPDYIQIWPG 168
Query: 184 HG 185
HG
Sbjct: 169 HG 170
>ref|NP_376776.1| (NC_003106) 206aa long hypothetical protein [Sulfolobus tokodaii]
dbj|BAB65885.1| (AP000984) 206aa long hypothetical protein [Sulfolobus tokodaii]
Length = 206
Score = 44.7 bits (104), Expect = 7e-04
Identities = 49/190 (25%), Positives = 83/190 (42%), Gaps = 25/190 (13%)
Query: 15 AYIVKLSSGIDFIIDPGFSSSEWVLEN-AKNPKAILITHGHYDHVWDGAQLSKLLKNTPI 73
A++++ G + ++D G S L+N K+ K I+ TH H DH+ +++ L
Sbjct: 13 AFLIETDEG-NILVDTGTPGSGKTLQNYLKDVKYIIFTHSHVDHIGGASEIRGLTNAEFC 71
Query: 74 YAPKDDVF----MLENDIFH-LGMPVFSPNFSV------PCNKGCTTLEIANTT--IKYW 120
K + ++ + H LG+ + P FS+ P CT + +K
Sbjct: 72 IHEKGKEYLEKGLIRKPVVHSLGLKIVFPLFSLFSRGLKPTKVDCTLKDEEEIVKGVKVL 131
Query: 121 HFPGHTPGCSIIEIEGV--IFSGDFIFYRSIGRY-DFP--YSNEKDMKESLLRFQNLDFP 175
+ PGHT + +E + + GD + R G Y +P Y N +M +S+ R +L
Sbjct: 132 YTPGHTDDSISLYLEPINSVIVGDMLQGR--GNYLTYPQIYENMGEMIKSVQRVLDL--- 186
Query: 176 KDIEIYPGHG 185
K IY HG
Sbjct: 187 KPSFIYVSHG 196
>ref|NP_357719.1| (NC_003098) Conserved hypothetical protein [Streptococcus
pneumoniae R6]
gb|AAK98929.1| (AE008396) Conserved hypothetical protein [Streptococcus pneumoniae
R6]
Length = 610
Score = 44.3 bits (103), Expect = 9e-04
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 23 GIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
GID++I P +S ++++N KA+LITHGH DH+ G N PIYA + +
Sbjct: 101 GIDYVI-PDYS---YIVDNIDRVKAVLITHGHEDHI-GGIPFLLKQANVPIYAGPLALAL 155
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-VIFSG 141
+ + G+ + + + N T + T + H G I +G ++ +G
Sbjct: 156 IRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKIVCTG 215
Query: 142 DFIF 145
DF F
Sbjct: 216 DFKF 219
>ref|NP_393565.1| (NC_002578) conserved hypothetical protein [Thermoplasma
acidophilum]
emb|CAC11234.1| (AL445063) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 207
Score = 44.3 bits (103), Expect = 9e-04
Identities = 50/196 (25%), Positives = 83/196 (41%), Gaps = 28/196 (14%)
Query: 11 VEENAYIVKLSSGIDFIIDPGFSSS-----EWVLENAKNPKAILITHGHYDHVWDGAQLS 65
V N+Y++ L G + +ID G + ++ +N P +++TH H DHV ++S
Sbjct: 18 VTANSYLLTLD-GKNILIDTGTAGGGKKIIDYFNKNGTKPDYVIVTHHHADHVGGLKEIS 76
Query: 66 KLLKNTPIYAPKDDVFMLEND-----------IFHLGMPVFSPNFSV-PCNKGCTTLEIA 113
+ N IY P ++ ++ + GM F P V P +K +
Sbjct: 77 ERF-NPEIYVPDLEMKIIRGEEDPPKPRSFFGRMITGMLKFEPVKDVKPVSKA------S 129
Query: 114 NTTIKYWHFPGHTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQN 171
I+ PGHT G + I+E ++FSGD S G S ++ + +
Sbjct: 130 IPGIEEMATPGHTIGSTSYIVEDLHILFSGD-AAVESGGELKINKSFSYEINSAERSLEI 188
Query: 172 LDFPKDIEIYPGHGDK 187
+ K + PGHGDK
Sbjct: 189 IKGMKGYLVLPGHGDK 204
>ref|NP_344667.1| (NC_003028) metallo-beta-lactamase superfamily protein
[Streptococcus pneumoniae TIGR4]
gb|AAK74307.1| (AE007329) metallo-beta-lactamase superfamily protein
[Streptococcus pneumoniae TIGR4]
Length = 559
Score = 44.3 bits (103), Expect = 9e-04
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
Query: 23 GIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
GID++I P +S ++++N KA+LITHGH DH+ G N PIYA + +
Sbjct: 50 GIDYVI-PDYS---YIVDNIDRVKAVLITHGHEDHI-GGIPFLLKQANVPIYAGPLALAL 104
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-VIFSG 141
+ + G+ + + + N T + T + H G I +G ++ +G
Sbjct: 105 IRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKIVCTG 164
Query: 142 DFIF 145
DF F
Sbjct: 165 DFKF 168
>ref|NP_390528.1| (NC_000964) similar to hypothetical proteins [Bacillus subtilis]
sp|P54435|YRKH_BACSU Hypothetical protein yrkH
pir||F69976 conserved hypothetical protein yrkH - Bacillus subtilis
dbj|BAA12363.1| (D84432) YrkH [Bacillus subtilis]
emb|CAB14592.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]
Length = 295
Score = 43.9 bits (102), Expect = 0.001
Identities = 45/141 (31%), Positives = 65/141 (45%), Gaps = 24/141 (17%)
Query: 51 THGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTL 110
TH H DH+ G +++ K T + P D +E D P +G +
Sbjct: 91 THLHADHISGGRVIAEKTKAT-YWLPPKDAEEVEFDY-------------QPLEEG-NDI 135
Query: 111 EIANTTIKYW--HFPGHTPG-CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEK---DMKE 164
I NTTIK + PGHT G S I + + SGD +F SIGR D E D+++
Sbjct: 136 IIGNTTIKIQPIYSPGHTIGSTSFIVDDQYLLSGDILFIDSIGRPDLAGMAEDWVGDLRK 195
Query: 165 SLL-RFQNLDFPKDIEIYPGH 184
+L R++ L KD+ + P H
Sbjct: 196 TLYSRYKALS--KDLIVLPAH 214
>ref|NP_269869.1| (NC_002737) conserved hypothetical protein [Streptococcus pyogenes]
[Streptococcus pyogenes M1 GAS]
ref|NP_607939.1| (NC_003485) conserved hypothetical protein [Streptococcus pyogenes
MGAS8232]
gb|AAK34590.1| (AE006613) conserved hypothetical protein [Streptococcus pyogenes
M1 GAS]
gb|AAL98438.1| (AE010099) conserved hypothetical protein [Streptococcus pyogenes
MGAS8232]
Length = 560
Score = 43.9 bits (102), Expect = 0.001
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 23 GIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
GID++I P +S ++++N KA++ITHGH DH+ G N PIYA + +
Sbjct: 51 GIDYVI-PDYS---YIVDNLDRVKALVITHGHEDHI-GGIPFLLKQANIPIYAGPLALAL 105
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-VIFSG 141
+ + G+ + + + N T ++ T K H G I +G +I +G
Sbjct: 106 IRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGKIICTG 165
Query: 142 DFIF 145
DF F
Sbjct: 166 DFKF 169
>ref|NP_654720.1| (NC_003995) lactamase_B, Metallo-beta-lactamase superfamily
[Bacillus anthracis A2012] [Bacillus anthracis str.
A2012]
Length = 376
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/159 (28%), Positives = 69/159 (42%), Gaps = 20/159 (12%)
Query: 36 EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVF 95
++ EN ++ TH H DH+ G +L++ + T PKD E +F V
Sbjct: 156 QFAKENGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKD----AEEVVFSYEPLVE 211
Query: 96 SPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG-CSIIEIEGVIFSGDFIFYRSIGRYDF 154
+V G T +E I + PGHT G S I + SGD +F SIGR D
Sbjct: 212 GSVITV----GGTKIE-----IDALYSPGHTIGSTSFIVDNSYLLSGDILFVDSIGRPDL 262
Query: 155 PYSNE---KDMKESLL-RFQNLDFPKDIEIYPGHGDKTS 189
E D++ +L R++ L + + + P H K S
Sbjct: 263 AGKAEDWVSDLRNTLYSRYKELS--QSLIVLPAHYSKIS 299
>ref|NP_299439.1| (NC_002488) hydroxyacylglutathione hydrolase [Xylella fastidiosa
9a5c]
pir||H82591 hydroxyacylglutathione hydrolase XF2160 [imported] - Xylella
fastidiosa (strain 9a5c)
gb|AAF84959.1|AE004030_5 (AE004030) hydroxyacylglutathione hydrolase [Xylella fastidiosa
9a5c]
Length = 258
Score = 42.7 bits (99), Expect = 0.003
Identities = 41/144 (28%), Positives = 56/144 (38%), Gaps = 23/144 (15%)
Query: 13 ENAYIVKLSS--GIDFIIDPGFSSSEWVLENAKN---PKAILITHGHYDHVWDGAQLSKL 67
+N YI L + G I+DPG + +LE P AIL+TH H DH+ +L +
Sbjct: 10 DNNYIWTLIAPDGRAIIVDPGQALP--ILEAHSKGLIPTAILLTHHHADHIGGVPELLER 67
Query: 68 LKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTP 127
PIYAP D L G +L I + H PGHT
Sbjct: 68 WPTLPIYAPHDTRIALNYHRIGEG----------------DSLNILGLRFQVIHTPGHTH 111
Query: 128 GCSIIEIEGVIFSGDFIFYRSIGR 151
++F GD +F G+
Sbjct: 112 SHLTFIGNDLLFCGDTLFSLGCGQ 135
>ref|NP_109968.1| (NC_000912) similar to single stranded RNA(DNA) processing enzymes
[Mycoplasma pneumoniae]
sp|P75497|Y139_MYCPN Hypothetical protein MG139 homolog (A65_orf569)
pir||S73881 conserved hypothetical protein MG139 homolog A65_orf569 -
Mycoplasma pneumoniae (strain ATCC 29342)
gb|AAB96203.1| (AE000054) similar to single stranded RNA(DNA) processing enzymes
[Mycoplasma pneumoniae]
Length = 569
Score = 42.7 bits (99), Expect = 0.003
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 11 VEENAYIVKLSSGIDFI------IDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQL 64
+E + I+ + GI F ID S E+++EN KA+ ITHGH DH+ L
Sbjct: 34 IEYDDEIIIIDCGIKFASDDLLGIDGIIPSFEYLIENQAKVKALFITHGHEDHIGGVPYL 93
Query: 65 SKLLKNTPIYAPK 77
K + IYAP+
Sbjct: 94 LKQVDVPVIYAPR 106
>ref|NP_656979.1| (NC_003995) lactamase_B, Metallo-beta-lactamase superfamily
[Bacillus anthracis A2012] [Bacillus anthracis str.
A2012]
Length = 285
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 22/103 (21%)
Query: 45 PKAILITHGHYDHVWDGAQLSKLLKNTPIYA--------------PKDDVFMLENDIFHL 90
PKAI++THGH+DHV +L K + P+YA PK D +E +
Sbjct: 80 PKAIILTHGHFDHVGGIIELIKYW-DVPVYAHQMEIPFLTGQQSYPKPDP-TVEGGMVAK 137
Query: 91 GMPVFSPNFSVPCNKGCTTLEIANTT-----IKYWHFPGHTPG 128
P+F PN + L T ++ H PGHTPG
Sbjct: 138 MSPLF-PNEPIDLGNSIKVLPTDGTVPHVPGFRWIHTPGHTPG 179
>ref|NP_125729.1| (NC_000868) hypothetical protein [Pyrococcus abyssi]
pir||A75189 hypothetical protein PAB0023 - Pyrococcus abyssi (strain Orsay)
emb|CAB48960.1| (AJ248283) hypothetical protein [Pyrococcus abyssi]
Length = 204
Score = 42.4 bits (98), Expect = 0.003
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Query: 14 NAYIVKLSSGIDFIIDPGFSSS-----EWVLENAKNPKAILITHGHYDHVWDGAQLSKLL 68
N YIV + ++D G S+ E V + K KA+++THGH DH L ++L
Sbjct: 20 NVYIVDRGDHL-VLVDTGIESTCEKIIEAVKKLGKPLKAVILTHGHMDHTGSLRCLKEVL 78
Query: 69 KNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG 128
N + + +++V M+E N V + E+ + H PGHT G
Sbjct: 79 -NPIVASQEEEVEMIER------------NTGVKVDVKLKDGELFE-GFRVLHKPGHTKG 124
Query: 129 --CSIIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGHGD 186
C + E +F GD + + + P+ D + + R L + + P HG+
Sbjct: 125 SICLLDEDSKSLFVGDLVVEENGKLKEVPHQYSMDPEMNRKRIIELLEVEFENLMPAHGN 184
>ref|NP_071229.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
pir||H69550 conserved hypothetical protein AF2407 - Archaeoglobus fulgidus
gb|AAB91258.1| (AE001109) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 203
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 112 IANTTIKYWHFPGHTPGCSIIEI--EGVIFSGDFIFYRSI-GRYDFPYSNEKDMKESLLR 168
I NT I+ PGH+PG + +GD IF + GR+D S++K++ S+ +
Sbjct: 108 IGNTGIEILRTPGHSPGSLTFYLPEHSAAITGDLIFENGVPGRFDIYGSDKKELARSIEK 167
Query: 169 FQNLDFPKDIEIYPGHG 185
++LD I PGHG
Sbjct: 168 LRSLDAE---YILPGHG 181
>ref|NP_148499.1| (NC_000854) hypothetical protein [Aeropyrum pernix]
pir||E72452 hypothetical protein APE2265 - Aeropyrum pernix (strain K1)
dbj|BAA81277.1| (AP000064) 297aa long hypothetical protein [Aeropyrum pernix]
Length = 297
Score = 42.4 bits (98), Expect = 0.003
Identities = 51/180 (28%), Positives = 74/180 (40%), Gaps = 27/180 (15%)
Query: 26 FIIDPGFSSSEW-----VLENAKNPKAILITHGHYDHV---WDGAQLSKLLKNTPIYAPK 77
FI+DPG E +ITH H DH+ + G Q S L AP
Sbjct: 34 FIVDPGHGRKRAKQISKAAEKLGGEAVAIITHFHSDHLSTLYQGFQPSTAL------APV 87
Query: 78 DDVFMLENDIFHL----GMPVFSPN----FSVPCNKGCTTLEIANTT-IKYWHFPGHTPG 128
D+ M+++ + L G P F LE ++ PGHTPG
Sbjct: 88 KDLAMVQDRVMRLHYTFGYPFTGAEDYLLFKAEDVDNVEPLEAERIKPLRLVPLPGHTPG 147
Query: 129 CSIIEI-EGVIFSGDFIF-YRSIGRYDFPY-SNEKDMKESLLRFQNLDFPKDIEIYPGHG 185
+ +E +GV+++ D IF R + Y PY SN E+L R ++ ++ I P HG
Sbjct: 148 QTGVETPDGVLYAADSIFGERVLQTYAVPYHSNPCQALETLTRLRDRVNRLEV-IVPSHG 206
>gb|AAG51989.1|AC024260_27 (AC024260) glyoxalase II, putative; 78941-80643 [Arabidopsis
thaliana]
Length = 292
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/73 (36%), Positives = 35/73 (46%), Gaps = 9/73 (12%)
Query: 123 PGHTPGC-SIIEIEG-------VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDF 174
PGHT GC + + EG + F+GD + R GR DF + + ES + Q
Sbjct: 162 PGHTAGCVTYVTGEGADQPQPRMAFTGDAVLIRGCGRTDFQEGSSDQLYES-VHSQIFTL 220
Query: 175 PKDIEIYPGHGDK 187
PKD IYP H K
Sbjct: 221 PKDTLIYPAHDYK 233
>gb|AAB17995.1| (U74610) glyoxalase II [Arabidopsis thaliana]
Length = 256
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/73 (36%), Positives = 35/73 (46%), Gaps = 9/73 (12%)
Query: 123 PGHTPGC-SIIEIEG-------VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDF 174
PGHT GC + + EG + F+GD + R GR DF + + ES + Q
Sbjct: 126 PGHTAGCVTYVTGEGADQPQPRMAFTGDAVLIRGCGRTDFQGGSSDQLYES-VHSQIFSL 184
Query: 175 PKDIEIYPGHGDK 187
PKD IYP H K
Sbjct: 185 PKDTLIYPAHDYK 197
>ref|NP_564636.1| (NM_104236) glyoxalase II, putative [Arabidopsis thaliana]
gb|AAK96491.1| (AY052298) At1g53580/F22G10.9 [Arabidopsis thaliana]
gb|AAL25570.1| (AY058154) At1g53580/F22G10.9 [Arabidopsis thaliana]
Length = 256
Score = 42.4 bits (98), Expect = 0.003
Identities = 27/73 (36%), Positives = 35/73 (46%), Gaps = 9/73 (12%)
Query: 123 PGHTPGC-SIIEIEG-------VIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDF 174
PGHT GC + + EG + F+GD + R GR DF + + ES + Q
Sbjct: 126 PGHTAGCVTYVTGEGADQPQPRMAFTGDAVLIRGCGRTDFQEGSSDQLYES-VHSQIFTL 184
Query: 175 PKDIEIYPGHGDK 187
PKD IYP H K
Sbjct: 185 PKDTLIYPAHDYK 197
>gb|AAF89153.1|AF189297_1 (AF189297) class B carbapenemase GOB-7 [Chryseobacterium
meningosepticum]
Length = 252
Score = 42.4 bits (98), Expect = 0.003
Identities = 39/138 (28%), Positives = 58/138 (41%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESFPIIKGNIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLEN---DIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K D +L + LG F P K + + NT
Sbjct: 85 ALQDFKTETGAKFYADKADADVLRTGGKSDYELGKYGVTFKPVTPDKTLKDQDKITLGNT 144
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 145 TLTLLHHPGHTKGSCSFI 162
>ref|NP_103568.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
dbj|BAB49354.1| (AP002999) hypothetical protein [Mesorhizobium loti]
Length = 431
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/153 (28%), Positives = 66/153 (43%), Gaps = 9/153 (5%)
Query: 37 WVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTP--IYAPKDDVFMLENDIFHL-GMP 93
++ EN + + IL TH H DH + AQ K P I AP DV L I++ +
Sbjct: 197 YIAENGLSVEWILDTHPHADH-FSAAQYLKEKTGAPTAIGAPVVDVQRLWRGIYNWPELR 255
Query: 94 VFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIG--R 151
V + + G T ++ + + PGHT I F D IF G R
Sbjct: 256 VDGSQWDRLFSDG-DTFKVGSMAARVMFSPGHTLASITYVIGNAAFVHDTIFMPDSGTAR 314
Query: 152 YDFPYSNEKDMKESLLRFQNLDFPKDIEIYPGH 184
DFP + + + +S+ + LD P + ++ GH
Sbjct: 315 ADFPGGDARVLWKSIQKI--LDLPDETRLFTGH 345
>gb|AAH02937.1|AAH02937 (BC002937) Similar to hypothetical protein MNCb-5687 [Homo sapiens]
Length = 361
Score = 42.0 bits (97), Expect = 0.004
Identities = 45/175 (25%), Positives = 69/175 (38%), Gaps = 39/175 (22%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIY-APKDDVFMLENDIFHLGMPVFSPNFSVPCNK 105
AIL TH H+DH LS+ ++ +Y +P+D + L + + H +
Sbjct: 143 AILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDV------------- 189
Query: 106 GCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-------VIFSGDFIFYRSIGRYDFPYSN 158
+ + I+ PGHT G + ++G +FSGD +F GR N
Sbjct: 190 ----VSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF--EGN 243
Query: 159 EKDMKESLLRFQNLDFPKDIEIYPGH--GDKTSFFA--------EREHSKIWVSR 203
+ M SL L D ++PGH ++ FA RE WV R
Sbjct: 244 AETMLSSLDTV--LGLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR 296
>ref|NP_294381.1| (NC_001263) conserved hypothetical protein [Deinococcus
radiodurans]
pir||D75491 conserved hypothetical protein - Deinococcus radiodurans (strain
R1)
gb|AAF10237.1|AE001923_4 (AE001923) conserved hypothetical protein [Deinococcus radiodurans]
Length = 364
Score = 42.0 bits (97), Expect = 0.004
Identities = 39/158 (24%), Positives = 70/158 (43%), Gaps = 30/158 (18%)
Query: 14 NAYIVKLSSGIDFIIDPGFSSSEWVLENA-------KNPKAILITHGHYDHVWDGAQLSK 66
N +++ + G ++D G + ++ A + P+AI++THGH+DH+ GA +
Sbjct: 85 NIFLMGVPGGDWVLVDTGMPGTAGLIRQAAAQVYGARAPQAIVLTHGHFDHI--GALHAL 142
Query: 67 LLK-NTPIYAPKDDVFMLENDI------------FHLGMPVFSPNFSVPCNKGCTTLEIA 113
L + N P+YA D++ L ++ L P+F P TL
Sbjct: 143 LAEWNVPVYAHPDELPHLTGEVPYRFPDPTVGGLMSLTSPLFLPG-PYDFRPQVRTLPED 201
Query: 114 NTT-----IKYWHFPGHTPGCSII--EIEGVIFSGDFI 144
T ++ H PGHT G + E + ++ +GD +
Sbjct: 202 GTVPELPGWRWVHTPGHTEGHVSLWREADRLLIAGDAV 239
>ref|XP_087163.2| (XM_087163) KIAA1184 protein [Homo sapiens]
Length = 385
Score = 42.0 bits (97), Expect = 0.004
Identities = 45/175 (25%), Positives = 69/175 (38%), Gaps = 39/175 (22%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIY-APKDDVFMLENDIFHLGMPVFSPNFSVPCNK 105
AIL TH H+DH LS+ ++ +Y +P+D + L + + H +
Sbjct: 167 AILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDV------------- 213
Query: 106 GCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-------VIFSGDFIFYRSIGRYDFPYSN 158
+ + I+ PGHT G + ++G +FSGD +F GR N
Sbjct: 214 ----VSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF--EGN 267
Query: 159 EKDMKESLLRFQNLDFPKDIEIYPGH--GDKTSFFA--------EREHSKIWVSR 203
+ M SL L D ++PGH ++ FA RE WV R
Sbjct: 268 AETMLSSLDTV--LGLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR 320
>dbj|BAA86498.1| (AB033010) KIAA1184 protein [Homo sapiens]
Length = 380
Score = 42.0 bits (97), Expect = 0.004
Identities = 45/175 (25%), Positives = 69/175 (38%), Gaps = 39/175 (22%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIY-APKDDVFMLENDIFHLGMPVFSPNFSVPCNK 105
AIL TH H+DH LS+ ++ +Y +P+D + L + + H +
Sbjct: 162 AILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDV------------- 208
Query: 106 GCTTLEIANTTIKYWHFPGHTPGCSIIEIEG-------VIFSGDFIFYRSIGRYDFPYSN 158
+ + I+ PGHT G + ++G +FSGD +F GR N
Sbjct: 209 ----VSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF--EGN 262
Query: 159 EKDMKESLLRFQNLDFPKDIEIYPGH--GDKTSFFA--------EREHSKIWVSR 203
+ M SL L D ++PGH ++ FA RE WV R
Sbjct: 263 AETMLSSLDTV--LGLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQR 315
>ref|NP_636363.1| (NC_003902) hydroxyacylglutathione hydrolase [Xanthomonas
campestris pv. campestris str. ATCC 33913]
gb|AAM40287.1| (AE012196) hydroxyacylglutathione hydrolase [Xanthomonas campestris
pv. campestris str. ATCC 33913]
Length = 255
Score = 42.0 bits (97), Expect = 0.004
Identities = 41/135 (30%), Positives = 57/135 (41%), Gaps = 22/135 (16%)
Query: 21 SSGIDFIIDPGFSSSEWVLENAKN----PKAILITHGHYDHVWDGAQLSKLLKNTPIYAP 76
+ G I+DPG ++ VLE A+ P A L+TH H DH+ A+L + +Y P
Sbjct: 20 NDGRAVIVDPGQAAP--VLEAAQREGFTPVAALLTHHHADHIGGVAELQQHFPALELYGP 77
Query: 77 KDDVFMLENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEG 136
D+ MP S V T L I ++ PGHT +G
Sbjct: 78 DDE-----------RMP--SATRHVAHGDTVTALGIDFAVLE---VPGHTRSHVAYVGDG 121
Query: 137 VIFSGDFIFYRSIGR 151
+FSGD +F GR
Sbjct: 122 HLFSGDTLFSLGCGR 136
>gb|EAA02540.1| (AAAB01005245) ebiP92 [Anopheles gambiae str. PEST]
Length = 277
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/138 (27%), Positives = 58/138 (41%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 52 GTYDLTSYLIVTDKG-NILINTGTAESLPIIKGNIQKLGFNYKDIKILLLTQAHYDHT-G 109
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLEN---DIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
+ K YA K D +L + LG F P K + + NT
Sbjct: 110 ALEDFKTETGAKFYADKADADVLRTGGKSDYELGKYGVTFKPITPDRTLKDQDKITLGNT 169
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 170 TLTLLHHPGHTKGSCSFI 187
>gb|AAH08250.1|AAH08250 (BC008250) Similar to RIKEN cDNA 0610025L15 gene [Homo sapiens]
Length = 254
Score = 41.6 bits (96), Expect = 0.006
Identities = 23/64 (35%), Positives = 31/64 (47%), Gaps = 3/64 (4%)
Query: 123 PGHTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
PGHTPGC ++ + F+GD + R GR DF K + S + + P D I
Sbjct: 133 PGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHS-VHEKIFTLPGDCLI 191
Query: 181 YPGH 184
YP H
Sbjct: 192 YPAH 195
>gb|AAF89147.1|AF189291_1 (AF189291) class B carbapenemase GOB-3 [Chryseobacterium
meningosepticum]
Length = 252
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/138 (27%), Positives = 58/138 (41%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K D +L N + +G F P K + + NT
Sbjct: 85 ALQDLKTETGAKFYADKADADVLRTGGNSDYEMGKYGVTFKPVTPDKTLKDQDKITLGNT 144
Query: 116 TIKYWHFPGHTPG-CSII 132
+ H PGHT G CS I
Sbjct: 145 ILTLLHHPGHTKGSCSFI 162
>ref|NP_588246.1| (NC_003421) putative hydroxyacylglutathione hydrolase
[Schizosaccharomyces pombe]
pir||T40964 probable hydroxyacylglutathione hydrolase - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21784.1| (AL032681) putative hydroxyacylglutathione hydrolase
[Schizosaccharomyces pombe]
Length = 256
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/143 (26%), Positives = 51/143 (35%), Gaps = 25/143 (17%)
Query: 46 KAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNK 105
+AIL TH H DH L K + IY D +N + H+ +
Sbjct: 57 QAILTTHHHADHSGGNLNLKKEFPHVTIYGGSD-----QNGVSHV-------------LQ 98
Query: 106 GCTTLEIANTTIKYWHFPGHTPGCSII----EIEGVIFSGDFIFYRSIGRYDFPYSNEKD 161
TL I N I+ H P HT E +F+GD +F GR+ +
Sbjct: 99 DKETLRIGNVQIEALHTPCHTRDSICFYAHSSNEHAVFTGDTLFNAGCGRF---FEGTAA 155
Query: 162 MKESLLRFQNLDFPKDIEIYPGH 184
L P + IYPGH
Sbjct: 156 EMHIALNAVLSSLPNNTVIYPGH 178
>ref|NP_343676.1| (NC_002754) Conserved hypothetical protein [Sulfolobus
solfataricus]
gb|AAK42466.1| (AE006833) Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 272
Score = 41.6 bits (96), Expect = 0.006
Identities = 34/118 (28%), Positives = 50/118 (41%), Gaps = 29/118 (24%)
Query: 44 NPKAILITHGHYDHVWDGAQLSKLLKNTPI-YAPKDDVFML---------------ENDI 87
N + L THGH DH+ L K+ I Y PK+D + L ++DI
Sbjct: 40 NAEVQLATHGHADHI-----AGLLKKDAKIRYLPKEDYWSLTLMGRRAMIYGCSSKDSDI 94
Query: 88 FHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIF 145
F V N +E+ + I+ PGHTPG S ++ V+++GD F
Sbjct: 95 FTFDY--------VKENIESIDIEVRTSEIEVIKLPGHTPGHSGYIVDNVLYAGDAFF 144
>gb|AAG09063.1|AC018758_3 (AC018758) protein expressed in thyroid [Homo sapiens]
Length = 227
Score = 41.6 bits (96), Expect = 0.006
Identities = 23/64 (35%), Positives = 31/64 (47%), Gaps = 3/64 (4%)
Query: 123 PGHTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
PGHTPGC ++ + F+GD + R GR DF K + S + + P D I
Sbjct: 106 PGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHS-VHEKIFTLPGDCLI 164
Query: 181 YPGH 184
YP H
Sbjct: 165 YPAH 168
>ref|NP_055112.1| (NM_014297) protein expressed in thyroid [Homo sapiens]
dbj|BAA34595.1| (D83198) homology to a plant EST:RICS2753A [Homo sapiens]
Length = 227
Score = 41.6 bits (96), Expect = 0.006
Identities = 23/64 (35%), Positives = 31/64 (47%), Gaps = 3/64 (4%)
Query: 123 PGHTPGCS--IIEIEGVIFSGDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEI 180
PGHTPGC ++ + F+GD + R GR DF K + S + + P D I
Sbjct: 106 PGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHS-VHEKIFTLPGDCLI 164
Query: 181 YPGH 184
YP H
Sbjct: 165 YPAH 168
>ref|NP_599542.1| (NC_003450) COG0491:Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum]
dbj|BAB97683.1| (AP005274) Zn-dependent hydrolases, including glyoxylases
[Corynebacterium glutamicum ATCC 13032]
Length = 281
Score = 41.6 bits (96), Expect = 0.006
Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 50/200 (25%)
Query: 21 SSGIDFIIDPGFSSSE----WVLENAKNPKAI-------------------------LIT 51
S+ + +PG+SS E WV+ ++P++I L+T
Sbjct: 21 SASVVLCPNPGYSSLEGTNSWVIRAPEDPRSIVIDPGPEDEGHLNVLHSKAEEVGLILLT 80
Query: 52 HGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPV----FSPNFSVPCNKGC 107
H HYDH DGAQ + L N P+ A D + + H G + +P V G
Sbjct: 81 HRHYDHA-DGAQRFRQLTNAPVRA-MDPSYCAGAEEIHDGEIITIDGVTPQIEVVATPGH 138
Query: 108 TTLEIANTTIKYWHFPGHTPGCSIIEIEGVIFSGDFIFYRSIGRYDFPYS-NEKDMKESL 166
T ++ Y+ + G P S +EG++ SGD I GR+ S + D+ E L
Sbjct: 139 T-----RDSVSYFIWSG-VPHES--TLEGIV-SGDTI----AGRHTTMISETDGDLGEYL 185
Query: 167 LRFQNL-DFPKDIEIYPGHG 185
L + KDI + PGHG
Sbjct: 186 NSLAILEERGKDIPLLPGHG 205
>gb|AAF89148.1|AF189292_1 (AF189292) class B carbapenemase GOB-6 [Chryseobacterium
meningosepticum]
Length = 252
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K D +L N + +G F P K +++ N
Sbjct: 85 ALQDLKTETAAKFYADKADADVLRTGGNSDYEMGKYGVTFKPVTPDKTLKDQDKIKLGNI 144
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 145 TLTLLHHPGHTKGSCSFI 162
>ref|NP_348031.1| (NC_003030) Zn-dependent hydrolase, glyoxylase II family
[Clostridium acetobutylicum]
gb|AAK79371.1|AE007652_1 (AE007652) Zn-dependent hydrolase, glyoxylase II family
[Clostridium acetobutylicum]
Length = 298
Score = 41.2 bits (95), Expect = 0.007
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 22/162 (13%)
Query: 27 IIDPGFSSS------EWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDV 80
++D G ++S E +++N +PK I+ TH H DH IY + +
Sbjct: 31 LVDTGMNNSDARKIDEVLIKNGLHPKYIVNTHHHLDHCGGNTYFQNNYPGCLIYTSEKEK 90
Query: 81 FMLEN-DIFHLGMPVFSPNFSVPCNKGCTTL-----------EIANTTIKYWHFPGHTPG 128
+EN ++ G+ F + +K L +I + + PGHT
Sbjct: 91 VSMENIHLYPTGL--FGASAIKELHKSNKPLMVDYVLKEGENKINDEKFEVIALPGHTVD 148
Query: 129 -CSIIEIEGVIFSGDFIFYR-SIGRYDFPYSNEKDMKESLLR 168
I+ E V F GD +F + ++ +Y PY + D +E L+
Sbjct: 149 LIGIVTREKVCFLGDSVFSKETLQKYSLPYLYDVDKEEETLK 190
>ref|NP_349408.1| (NC_003030) Predicted Zn-dependent hydrolase from
metallo-beta-lactamase superfamily [Clostridium
acetobutylicum]
gb|AAK80748.1|AE007778_1 (AE007778) Predicted Zn-dependent hydrolase from
metallo-beta-lactamase superfamily [Clostridium
acetobutylicum]
Length = 273
Score = 41.2 bits (95), Expect = 0.007
Identities = 36/127 (28%), Positives = 60/127 (46%), Gaps = 24/127 (18%)
Query: 20 LSSGIDFIIDPGFSSSEWVLENAKNPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDD 79
L + DFI+ ++E PKAI++THGH+DHV +LSKL + P+Y + +
Sbjct: 49 LENSADFIL----KAAEKRFGKGSVPKAIILTHGHFDHVGSVIKLSKLW-SVPVYIHELE 103
Query: 80 V-FMLENDIFHLGMPVFS-----------PNFSVPCNKGCTTLEIANTTIKY---W---H 121
+ ++ + L P P+ S+ + + L ++++I Y W H
Sbjct: 104 MPYVTGKKDYPLADPTVDEGMVAKISQTFPHTSIDISSNVSPLP-SDSSIPYMPDWKWIH 162
Query: 122 FPGHTPG 128
PGHT G
Sbjct: 163 TPGHTDG 169
>gb|AAF89152.1|AF189296_1 (AF189296) class B carbapenemase GOB-2 [Chryseobacterium
meningosepticum]
Length = 252
Score = 40.8 bits (94), Expect = 0.010
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K DV +L + +G F P K +++ N
Sbjct: 85 ALQDFKTETAAKFYADKADVDVLRTGGKSDYEMGKYGVTFKPVTPDKTLKDQDKIKLGNI 144
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 145 TLTLLHHPGHTKGSCSFI 162
>gb|AAF04458.1|AF090141_1 (AF090141) GOB-1 carbapenemase [Chryseobacterium meningosepticum]
Length = 290
Score = 40.8 bits (94), Expect = 0.010
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 48 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 105
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K DV +L + +G F P K +++ N
Sbjct: 106 ALQDFKTETAAKFYADKADVDVLRTGGKSDYEMGKYGVTFKPVTPDKTLKDQDKIKLGNI 165
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 166 TLTLLHHPGHTKGSCSFI 183
>gb|AAF89146.1|AF189290_1 (AF189290) class B carbapenemase GOB-5 [Chryseobacterium
meningosepticum]
Length = 252
Score = 40.8 bits (94), Expect = 0.010
Identities = 37/138 (26%), Positives = 59/138 (41%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K+D +L + +G F P K +++ NT
Sbjct: 85 ALQDLKTETAAKFYADKEDADVLRTGGKSDYEMGKYGVTFKPVTPDKTLKDQDKIKLGNT 144
Query: 116 TIKYWHFPGHTPG-CSII 132
+ H PGHT G CS I
Sbjct: 145 ILTLLHHPGHTKGSCSFI 162
>gb|AAF89149.1|AF189293_1 (AF189293) class B carbapenemase GOB-4 [Chryseobacterium
meningosepticum]
Length = 252
Score = 40.8 bits (94), Expect = 0.010
Identities = 38/138 (27%), Positives = 58/138 (41%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K D +L N + +G F P K + + NT
Sbjct: 85 ALQDLKTETAAKFYADKADADVLRTGGNSDYEMGKYGVTFKPVTPDKTLKDQDKITLGNT 144
Query: 116 TIKYWHFPGHTPG-CSII 132
+ H PGHT G CS I
Sbjct: 145 ILTLLHHPGHTKGSCSFI 162
>ref|NP_496556.1| (NM_064155) Metallo-beta-lactamase superfamily [Caenorhabditis
elegans]
pir||T26496 hypothetical protein Y17G7B.3 - Caenorhabditis elegans
emb|CAA19450.1| (AL023828) contains similarity to Pfam domain: PF00753
(Metallo-beta-lactamase superfamily), Score=131.7,
E-value=4.4e-36, N=1~cDNA EST yk399f1.5 comes from this
gene~cDNA EST yk628c2.5 comes from this gene
[Caenorhabditis elegans]
Length = 260
Score = 40.8 bits (94), Expect = 0.010
Identities = 37/147 (25%), Positives = 56/147 (37%), Gaps = 29/147 (19%)
Query: 47 AILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFMLENDIFHLGMPVFSPNFSVPCNKG 106
A+L TH HYDH + N I + ++ + H M
Sbjct: 51 AVLTTHHHYDHCGGNEGFRRQFPNVMILGGDSRIPAMDRHVKHGDM-------------- 96
Query: 107 CTTLEIANTTIKYWHFPGHTPGCSIIEI---------EGVIFSGDFIFYRSIGRYDFPYS 157
E A IK P HT G I GV+F+GD +F GR+ +
Sbjct: 97 ---AEFAGLQIKCLSTPCHTSGHICYHITNPAADSTSPGVVFTGDTLFIAGCGRFFEGTA 153
Query: 158 NEKDMKESLLRFQNLDFPKDIEIYPGH 184
+ D+ + + +NL P + +I+PGH
Sbjct: 154 PQMDVALNEI-LKNL--PVETQIFPGH 177
>gb|AAF89150.1|AF189294_1 (AF189294) class B carbapenemase GOB-1 [Chryseobacterium
meningosepticum]
gb|AAF89151.1|AF189295_1 (AF189295) class B carbapenemase GOB-1 [Chryseobacterium
meningosepticum]
Length = 252
Score = 40.8 bits (94), Expect = 0.010
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 16/138 (11%)
Query: 9 GAVEENAYIVKLSSGIDFIIDPGFSSSEWVLE--------NAKNPKAILITHGHYDHVWD 60
G + +Y++ G + +I+ G + S +++ N K+ K +L+T HYDH
Sbjct: 27 GTYDLASYLIVTDKG-NILINTGTAESLPIIKANIQKLGFNYKDIKILLLTQAHYDHT-G 84
Query: 61 GAQLSKLLKNTPIYAPKDDVFMLE---NDIFHLGM--PVFSPNFSVPCNKGCTTLEIANT 115
Q K YA K DV +L + +G F P K +++ N
Sbjct: 85 ALQDFKTETAAKFYADKADVDVLRTGGKSDYEMGKYGVTFKPVTPDKTLKDQDKIKLGNI 144
Query: 116 TIKYWHFPGHTPG-CSII 132
T+ H PGHT G CS I
Sbjct: 145 TLTLLHHPGHTKGSCSFI 162
>gb|AAG10453.1|AF279106_15 (AF279106) predicted metallobeta lactamase fold protein [uncultured
proteobacterium EBAC31A08]
Length = 265
Score = 40.8 bits (94), Expect = 0.010
Identities = 50/167 (29%), Positives = 69/167 (40%), Gaps = 21/167 (12%)
Query: 27 IIDPGFSSSEWVLENAK----NPKAILITHGHYDHVWDGAQLSKLLKNTPIYAPKDDVFM 82
++DPG + SE + E K K I +TH H DH LSK L N P+Y D
Sbjct: 32 LVDPGPNISEHLDEIIKAGDGKIKRIFVTHTHTDHSPAALPLSKTL-NVPMYGRLVDGES 90
Query: 83 LENDIFHLGMPVFSPNFSVPCNKGCTTLEIANTTIKYWHFPGHTPG--CSIIEIEGVIFS 140
D F P+ + +E T++ H PGH C +I+ + +
Sbjct: 91 SWED------ETFIPDIIL---NDKDIIETDEYTLEVIHTPGHASNHLCFLIKDTKCLLT 141
Query: 141 GDFIFYRSIGRYDFPYSNEKDMKESLLRFQNLDFPKDIEIY-PGHGD 186
GD I S P N SL + LDF DI+ + PGHG+
Sbjct: 142 GDHIMDGSTVVIGPPDGNMTSYINSLEKL--LDF--DIDCFAPGHGN 184
Database: /home/scwang/download_20020708_db/nr
Posted date: Aug 7, 2002 12:55 PM
Number of letters in database: 324,149,939
Number of sequences in database: 1,026,957
Lambda K H
0.322 0.141 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 146,166,878
Number of Sequences: 1026957
Number of extensions: 6249586
Number of successful extensions: 11323
Number of sequences better than 1.0e-02: 137
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 11111
Number of HSP's gapped (non-prelim): 139
length of query: 205
length of database: 324,149,939
effective HSP length: 115
effective length of query: 90
effective length of database: 206,049,884
effective search space: 18544489560
effective search space used: 18544489560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 94 (40.8 bits)