BLASTP 2.2.1 [Apr-13-2001]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15645480|ref|NP_207655.1| hypothetical protein
[Helicobacter pylori 26695]
         (246 letters)

Database: /home/scwang/download_20020708_db/nr
           1,026,957 sequences; 324,149,939 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_207655.1|  (NC_000915) hypothetical protein [Helicoba...   489  e-138
ref|NP_223513.1|  (NC_000921) putative [Helicobacter pylori ...   424  e-118
ref|NP_282631.1|  (NC_002163) putative integral membrane pro...   101  8e-21
ref|NP_348181.1|  (NC_003030) Heavy-metal-associated domain ...    89  6e-17
ref|NP_273801.1|  (NC_003112) conserved hypothetical protein...    87  1e-16
ref|NP_283749.1|  (NC_003116) hypothetical protein NMA0970 [...    87  2e-16
ref|NP_488751.1|  (NC_003272) unknown protein [Nostoc sp. PC...    75  8e-13
ref|NP_231078.1|  (NC_002505) conserved hypothetical protein...    73  2e-12
ref|NP_250238.1|  (NC_002516) hypothetical protein [Pseudomo...    71  1e-11
ref|NP_519405.1|  (NC_003295) PROBABLE TRANSMEMBRANE PROTEIN...    66  4e-10
ref|NP_563453.1|  (NC_003366) probable c-type cytochrome bio...    51  1e-05
ref|NP_439046.1|  (NC_000907) thiol:disulfide interchange pr...    49  6e-05
ref|NP_274527.1|  (NC_003112) thiol:disulfide interchange pr...    48  8e-05
ref|NP_284434.1|  (NC_003116) putative disulphide isomerase ...    47  1e-04
sp|Q9JTL9|DSBD_NEIMA  Thiol:disulfide interchange protein ds...    47  1e-04
ref|NP_245158.1|  (NC_002663) DsbD [Pasteurella multocida] >...    46  3e-04
sp|Q9CP40|DSBD_PASMU  Thiol:disulfide interchange protein ds...    46  3e-04
ref|NP_232328.1|  (NC_002505) thiol:disulfide interchange pr...    45  0.001
ref|NP_111234.1|  (NC_002689) Predicted threonine efflux pro...    44  0.002
ref|NP_634469.1|  (NC_003901) conserved protein [Methanosarc...    42  0.008
ref|NP_222971.1|  (NC_000921) putative CYTOCHROME C-TYPE BIO...    42  0.008
sp|Q9KJZ3|DSBD_PSESP  Thiol:disulfide interchange protein ds...    42  0.008
>ref|NP_207655.1| (NC_000915) hypothetical protein [Helicobacter pylori 26695]
 pir||E64627 hypothetical protein HP0861 - Helicobacter pylori (strain 26695)
 gb|AAD07915.1| (AE000596) H. pylori predicted coding region HP0861 [Helicobacter
           pylori 26695]
          Length = 246

 Score =  489 bits (1260), Expect = e-138
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MQMMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGR 60
           MQMMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGR
Sbjct: 1   MQMMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGR 60

Query: 61  ISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILICLALLGARMEKLSFQIPFISFLM 120
           ISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILICLALLGARMEKLSFQIPFISFLM
Sbjct: 61  ISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILICLALLGARMEKLSFQIPFISFLM 120

Query: 121 KKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
           KKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL
Sbjct: 121 KKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180

Query: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPHAMHHQNNTTQHDHKG 240
           MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPHAMHHQNNTTQHDHKG
Sbjct: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPHAMHHQNNTTQHDHKG 240

Query: 241 VHSHEH 246
           VHSHEH
Sbjct: 241 VHSHEH 246
>ref|NP_223513.1| (NC_000921) putative [Helicobacter pylori J99]
 pir||F71887 hypothetical protein jhp0795 - Helicobacter pylori (strain J99)
 gb|AAD06371.1| (AE001509) putative [Helicobacter pylori J99]
          Length = 245

 Score =  424 bits (1089), Expect = e-118
 Identities = 213/244 (87%), Positives = 224/244 (91%)

Query: 1   MQMMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGR 60
           MQMM NLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQ+ CHALYNVGR
Sbjct: 1   MQMMQNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQIACHALYNVGR 60

Query: 61  ISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILICLALLGARMEKLSFQIPFISFLM 120
           ISTYMLLGAI A LG+SLSVSMGFRGVL +SMGI+LI LALLGA+ EKLSFQIPFISFLM
Sbjct: 61  ISTYMLLGAITAGLGNSLSVSMGFRGVLLMSMGIVLILLALLGAKAEKLSFQIPFISFLM 120

Query: 121 KKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
           KKTLQSQN+LGLYFLGVLNGFLPCMMVYSFLASVILSHS FMGAMLGLSFGLGTS+PLFL
Sbjct: 121 KKTLQSQNVLGLYFLGVLNGFLPCMMVYSFLASVILSHSTFMGAMLGLSFGLGTSVPLFL 180

Query: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPHAMHHQNNTTQHDHKG 240
           MGIFLSKIS+SYRKFFNLLSK LMGVFGLY+LYMGIMLI+H+ PHAM HQNN T      
Sbjct: 181 MGIFLSKISISYRKFFNLLSKGLMGVFGLYVLYMGIMLISHQTPHAMRHQNNATPQQEGH 240

Query: 241 VHSH 244
            H H
Sbjct: 241 FHDH 244
>ref|NP_282631.1| (NC_002163) putative integral membrane protein [Campylobacter
           jejuni]
 pir||B81296 probable integral membrane protein Cj1493c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
 emb|CAB73915.1| (AL139078) putative integral membrane protein [Campylobacter
           jejuni]
          Length = 219

 Score =  101 bits (251), Expect = 8e-21
 Identities = 74/221 (33%), Positives = 117/221 (52%), Gaps = 19/221 (8%)

Query: 6   NLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYM 65
           ++ FL +   A   S GHC  MCGG    F  I  +  ++  + LT   +YN+ RI  Y+
Sbjct: 2   SIDFLAIISVAFLSSFGHCYSMCGGFNLLF--INLNSKSNNLFLLTF--IYNLFRIFAYI 57

Query: 66  LLGAIAASLGHSLSVSMGFRGVLFISMGIILICLAL-LGARMEKLSF---QIPFISFLMK 121
           +LG I  + G+ L+++   + + F  +GI ++ L   L  R   LSF    + F SF+ K
Sbjct: 58  VLGIIFGTFGNILAINAKVQSLSFFILGIFMMILGFALIFRGNMLSFIENNVFFDSFVKK 117

Query: 122 KTLQSQNILGL---YFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPL 178
              +S+N  GL    FLG  NGF+PC +VY F+A+ +   + F G ++ + FG+ T +P 
Sbjct: 118 IIKKSKNFKGLKSAIFLGFSNGFVPCGLVYFFIANAMSKQNIFEGILVMMIFGIST-LPA 176

Query: 179 FLMGIFLSKISVSYRKF----FNLLSKILMGVFGLYILYMG 215
            L   F SKIS  +  F    FN LS  ++  +G+ + Y+G
Sbjct: 177 ML---FFSKISQFFSDFLKNLFNYLSYGVIVCYGINLAYIG 214
>ref|NP_348181.1| (NC_003030) Heavy-metal-associated domain (N-terminus) and
           membrane-bounded cytochrome biogenesis cycZ-like domain,
           possible membrane copper tolerance protein [Clostridium
           acetobutylicum]
 gb|AAK79521.1|AE007665_8 (AE007665) Heavy-metal-associated domain (N-terminus) and
           membrane-bounded cytochrome biogenesis cycZ-like domain,
           possible membrane copper tolerance protein [Clostridium
           acetobutylicum]
          Length = 601

 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 65/235 (27%), Positives = 114/235 (47%), Gaps = 12/235 (5%)

Query: 12  MFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYMLLGAIA 71
           +F+  +  S+ HCVGMCGGI+ + S    +K  + S  +    LYN GR+ +Y +LG I 
Sbjct: 111 IFIVGVLTSI-HCVGMCGGILLSQS---ITKEGNKSSSIKSAILYNSGRVLSYTILGGIV 166

Query: 72  ASLGHSLSVSMGFRGVL--FISMGIILICLALLGARM-EKLSFQIPFISFLMKKTLQSQN 128
            +LG   ++S+G +  L  F +  +I++ L + G  +  K+  ++PF   + KK  ++  
Sbjct: 167 GALGSVFNLSLGLKSFLQIFAAAFMIIMGLNMSGFSLFRKIQLKLPFPRRIFKKAPKTP- 225

Query: 129 ILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFLMGIFLSKI 188
               +F+G+LNG +PC  + +     + + S   GA+    F LGT   +   G+    I
Sbjct: 226 ----FFIGMLNGLMPCGPLQTMQLYALSTGSPIKGALSLFVFSLGTIPLMMTFGVLSGFI 281

Query: 189 SVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPHAMHHQNNTTQHDHKGVHS 243
           S    K     S IL+ V G+ +   G+ L    +P     +N+      K  ++
Sbjct: 282 SKGSTKVLLKFSGILVMVLGIIMGGRGLALAGVNVPTVSSIKNSVLASPSKDTNN 336
>ref|NP_273801.1| (NC_003112) conserved hypothetical protein [Neisseria meningitidis
           MC58]
 pir||D81161 conserved hypothetical protein NMB0759 [imported] - Neisseria
           meningitidis (group B strain MD58)
 gb|AAF41172.1| (AE002430) conserved hypothetical protein [Neisseria meningitidis
           MC58]
          Length = 242

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 66/224 (29%), Positives = 114/224 (50%), Gaps = 17/224 (7%)

Query: 1   MQMMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGR 60
           + M H+++FL +FL        HC+GMCGG+ SAF+      +  F   L    L N GR
Sbjct: 19  LPMNHDITFLTLFLLGFFGGT-HCIGMCGGLSSAFALQLPPHINRFWLIL----LLNTGR 73

Query: 61  ISTYMLLGAIAASLGH---SLSVSMGFRGVLFISMGIILICLAL-------LGARMEKLS 110
           +S+Y  +G I   +G    SL  +   + +L+ +  ++L+ L L       L A++EK+ 
Sbjct: 74  VSSYTAIGLILGLIGQVGVSLDQTRVLQNILYTAANLLLLFLGLYLSGISSLAAKIEKIG 133

Query: 111 FQI-PFISFLMKKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLS 169
             I   ++ ++ + L  ++I     +G+L G+LPC +VYS     + S SA  G +  L+
Sbjct: 134 KPIWRNLNPILNRLLPIKSIPACLAVGILWGWLPCGLVYSASLYALGSGSAATGGLYMLA 193

Query: 170 FGLGTSMPLFLMGIF-LSKISVSYRKFFNLLSKILMGVFGLYIL 212
           F LGT   L  +GIF L    +   ++  L + + + ++ L+ L
Sbjct: 194 FALGTLPNLLAIGIFSLQLKKIMQNRYIRLCTGLSVSLWALWKL 237
>ref|NP_283749.1| (NC_003116) hypothetical protein NMA0970 [Neisseria meningitidis
           Z2491]
 pir||A81944 hypothetical protein NMA0970 [imported] - Neisseria meningitidis
           (group A strain Z2491)
 emb|CAB84240.1| (AL162754) hypothetical protein NMA0970 [Neisseria meningitidis
           Z2491]
          Length = 222

 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 66/222 (29%), Positives = 113/222 (50%), Gaps = 17/222 (7%)

Query: 3   MMHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRIS 62
           M H+++FL +FL        HC+GMCGG+ SAF+      +  F   L    L N GR+S
Sbjct: 1   MNHDITFLTLFLLGFFGGT-HCIGMCGGLSSAFALQLPPHINRFWLIL----LLNTGRVS 55

Query: 63  TYMLLGAIAASLGH---SLSVSMGFRGVLFISMGIILICLAL-------LGARMEKLSFQ 112
           +Y  +G I   +G    SL  +   + +L+ +  ++L+ L L       L A++EK+   
Sbjct: 56  SYTAIGLILGLIGQVGVSLDQTRVLQNILYTAANLLLLFLGLYLSGISSLAAKIEKIGKP 115

Query: 113 I-PFISFLMKKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFG 171
           I   ++ ++ + L  ++I     +G+L G+LPC +VYS     + S SA  G +  L+F 
Sbjct: 116 IWRNLNPILNRLLPIKSIPACLAVGILWGWLPCGLVYSASLYALGSGSAATGGLYMLAFA 175

Query: 172 LGTSMPLFLMGIF-LSKISVSYRKFFNLLSKILMGVFGLYIL 212
           LGT   L  +GIF L    +   ++  L + + + ++ L+ L
Sbjct: 176 LGTLPNLLAIGIFSLQLKKIMQNRYIRLCTGLSVSLWALWKL 217
>ref|NP_488751.1| (NC_003272) unknown protein [Nostoc sp. PCC 7120]
 dbj|BAB76410.1| (AP003597) ORF_ID:alr4711~unknown protein [Nostoc sp. PCC 7120]
          Length = 423

 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 72/250 (28%), Positives = 108/250 (42%), Gaps = 44/250 (17%)

Query: 7   LSFLGMFLAALSMSLGHCVGMCGGIVSAFS--------QIRFSKVTS-------FSYQLT 51
           L FLG F        GHC GMCG +  AFS        +    K TS       +  QL 
Sbjct: 10  LGFLGSF--------GHCFGMCGPLTVAFSLSHQHTTSEKDSQKQTSPTKTNPTWQQQLK 61

Query: 52  CHALYNVGRISTYMLLGAIAASLGHSL-------SVSMGFRGVLFISMGIILICLALLGA 104
            H L N+GR+ +Y L+GA    +G  L        V   FR V+ I  G++LI   L G 
Sbjct: 62  FHFLLNLGRMLSYALVGAGLRGVGSVLLQGGQLAGVGSDFRRVMAIITGVMLIWFGL-GQ 120

Query: 105 RMEKLSFQIPFISFLMKKTLQSQNILGLY------------FLGVLNGFLPCMMVYSFLA 152
               L   IP +  L+K  L ++   G+              LG+  G +PC  +Y+   
Sbjct: 121 LAPNLLPHIPLLHPLLKGNLHNRLSAGMVKLSLQPRWWTPTLLGMTWGLMPCGFLYAAQI 180

Query: 153 SVILSHSAFMGAMLGLSFGLGTSMPLFLMGIFLSKISVSYR-KFFNLLSKILMGVFGLYI 211
               + S +MG    L+FGLGT   +  +G+  S +S   R + F L   I + +  + +
Sbjct: 181 KAAETGSLWMGGATMLAFGLGTLPTMLGVGVSTSLVSQDRRSQLFRLGGWITLTIGTITL 240

Query: 212 LYMGIMLINH 221
           L  G  ++++
Sbjct: 241 LRTGDTMVDY 250
>ref|NP_231078.1| (NC_002505) conserved hypothetical protein [Vibrio cholerae]
 pir||G82199 conserved hypothetical protein VC1435 [imported] - Vibrio cholerae
           (group O1 strain N16961)
 gb|AAF94592.1| (AE004222) conserved hypothetical protein [Vibrio cholerae]
          Length = 224

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 67/223 (30%), Positives = 107/223 (47%), Gaps = 19/223 (8%)

Query: 9   FLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYMLLG 68
           +LG ++  L +  GHC+GMCGGI SA   +  SK +           YN+GR+ +Y L+G
Sbjct: 5   YLGAWVVGL-LGAGHCLGMCGGI-SALLTLDPSKSSP-----ALLLYYNLGRLLSYALIG 57

Query: 69  AIAASLGHSLSVSMGFRGVLF---ISMGIILICLALLGAR-------MEKLSFQI-PFIS 117
            I   +  SL+  +  +  L    I   +++I L L   R       +EK+  +I  +IS
Sbjct: 58  GIVGGITASLTELIDVQSALVWLRIFAAVLMIVLGLYIGRWWFGLLWLEKVGQKIWRWIS 117

Query: 118 FLMKKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMP 177
            L K  L  +        G++ G+LPC +VYS L    ++ S   GA++ LSFG GT   
Sbjct: 118 PLGKTLLPLKKQWHALPFGLVWGWLPCGLVYSMLTWSAVAGSFSQGALIMLSFGFGTLPA 177

Query: 178 LFLMGIFLSKI-SVSYRKFFNLLSKILMGVFGLYILYMGIMLI 219
           +   G   +K+        F   + IL+  +GL+  Y  + L+
Sbjct: 178 MLASGWGANKLMHWQNSHLFRQCAAILVIGYGLFTAYDAVKLM 220
>ref|NP_250238.1| (NC_002516) hypothetical protein [Pseudomonas aeruginosa]
 pir||D83451 hypothetical protein PA1547 [imported] - Pseudomonas aeruginosa
           (strain PAO1)
 gb|AAG04936.1|AE004583_1 (AE004583) hypothetical protein [Pseudomonas aeruginosa]
          Length = 227

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 59/213 (27%), Positives = 106/213 (49%), Gaps = 15/213 (7%)

Query: 12  MFLAALSMSL---GHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYMLLG 68
           + ++AL + L   GHC+GMCGG++ A +    ++      +L     YN+GRI +Y   G
Sbjct: 7   LLVSALILGLLGGGHCLGMCGGLMGALTLAIPAEQRGRRLRLLL--AYNLGRILSYACAG 64

Query: 69  AIAASLGHSLSVSMGFRGVLFISMGIILICLALLGA-------RMEKLSFQI-PFISFLM 120
            +    G +++ +    G L +  G++LI + L  A       R+E L   +   +    
Sbjct: 65  LLLGLAGWAVARTP-LAGALRVVAGLLLIAMGLYLAGWWSGLTRVEALGRGLWRHLEPFA 123

Query: 121 KKTLQSQNILGLYFLGVLNGFLPCMMVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
           ++ L   ++     LG + G+LPC +VYS L       SA   A+L L+FGLGT   L  
Sbjct: 124 RRLLPVSSLPRALLLGAIWGWLPCGLVYSTLLWATSQGSALDSALLMLAFGLGTWPVLLA 183

Query: 181 MGIFLSKI-SVSYRKFFNLLSKILMGVFGLYIL 212
            G+   ++ ++  R+   ++  +++ +FGL+ L
Sbjct: 184 TGMAAERVTALLRRRGVRIVGGLMVILFGLWTL 216
>ref|NP_519405.1| (NC_003295) PROBABLE TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]
 emb|CAD14986.1| (AL646063) PROBABLE TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]
          Length = 248

 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 65/232 (28%), Positives = 112/232 (48%), Gaps = 30/232 (12%)

Query: 4   MHNLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIR-----FSKVTSFSYQLTCHALYNV 58
           M   + L +FL AL   + HC+ MC GI  A  + +      S+   +  QL  H    +
Sbjct: 1   MSAAALLSVFLIALLGGV-HCLAMCSGIALAAERAQPAVRIVSRRRLWFEQLVMH----L 55

Query: 59  GRISTYMLLGAIAASLGHS------LSVSMGF---RGVLFISMGIILICLALL----GAR 105
           GR++TY LLGA   +LG +      L +  G       L ++ G++L+         GA 
Sbjct: 56  GRLTTYALLGAAMGALGATVWRQQWLPIQRGLFALASALLLAYGLLLLSRTAADVWRGAW 115

Query: 106 MEKLSFQIP-----FISFLMKKTLQSQ-NILGLYFLGVLNGFLPCMMVYSFLASVILSHS 159
           +E++  ++        S +   +L+++  + G Y  G+  G +PC MVY  LA  +L+ +
Sbjct: 116 LERILGRLSGGLAAVASGVRASSLRARFPLAGRYLTGLAWGLVPCGMVYGALAVALLAGN 175

Query: 160 AFMGAMLGLSFGLGTSMPLFLM-GIFLSKISVSYRKFFNLLSKILMGVFGLY 210
           A  GA++ L+FG GT   L +M G+      VS  ++   ++ I +  FG++
Sbjct: 176 AASGAVVMLAFGAGTLPNLLMMSGVAGWLRGVSRMRWARGVAGIGIAAFGIW 227
>ref|NP_563453.1| (NC_003366) probable c-type cytochrome biogenesis protein
           [Clostridium perfringens]
 dbj|BAB82243.1| (AP003194) probable c-type cytochrome biogenesis protein
           [Clostridium perfringens]
          Length = 230

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 57/225 (25%), Positives = 109/225 (48%), Gaps = 30/225 (13%)

Query: 7   LSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYML 66
           LSF    +A+ S      + +  G V   S+++ +K  +F Y L    ++++G   T+ +
Sbjct: 21  LSFFAGVVASFSTCTLSSIPLLIGYVQG-SEVKDNK-KAFKYSL----IFSIGLGITFTV 74

Query: 67  LGAIAASLGHSLSVSMGFRGVL--FISMGIILICLALLGARMEKLSFQIPFISFLMKKTL 124
           +G + A +G +   +  F  ++  FI +G  L  L ++    +K            K T 
Sbjct: 75  IGLLTALIGKAFLGAGKFWYIILAFIMIGSGLQVLDVINLFGDKKD--------ACKITK 126

Query: 125 QSQNILGLYFLGVLNGFL--PCM--MVYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
           + + IL  +FLG+L+G L  PC   ++ + +A +  S +  +G ++ L + LG S+ + L
Sbjct: 127 KREGILDAFFLGILSGILASPCATPIMAAIIAFIAASGNLVIGMIMLLMYSLGHSVLIIL 186

Query: 181 MGI---FLSKISVSY------RKFFNLLSKILMGVFGLYILYMGI 216
            G     + KI+ S       R   N+L  I++ + GLY+ Y+G+
Sbjct: 187 AGTSFGLVEKIAYSENGKKIGRVLKNILGTIII-LVGLYLFYLGV 230
>ref|NP_439046.1| (NC_000907) thiol:disulfide interchange protein (dsbD) [Haemophilus
           influenzae Rd]
 sp|P44919|DSBD_HAEIN Thiol:disulfide interchange protein dsbD precursor (C-type
           cytochrome biogenesis protein cycZ)
 pir||A64100 inner membrane copper tolerance protein cycZ homolog - Haemophilus
           influenzae (strain Rd KW20)
 gb|AAC22543.1| (U32770) thiol:disulfide interchange protein (dsbD) [Haemophilus
           influenzae Rd]
          Length = 579

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 56/227 (24%), Positives = 102/227 (44%), Gaps = 20/227 (8%)

Query: 8   SFLGMFLAALSMSLGHCVGMCGGIVSAF---SQIRFSKVTSFSYQLTCHALYNVGRISTY 64
           +  G F+  L ++   CV     ++SA     Q R + + +FS       LY  G   TY
Sbjct: 177 AIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAF----LYVQGMALTY 232

Query: 65  MLLGAIAASLGHSLSVSMGFRGVLF-ISMGIILICLALLGARMEKL--SFQIPFISFLMK 121
            LLG   A++G    +++    V+  +S+  + + L++ G    +L  S Q    ++  K
Sbjct: 233 TLLGLAVAAIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQK 292

Query: 122 KTLQSQNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMP 177
           +T  S    G + +G++ G +  PC    +   L  V  S   F GA+      LG  +P
Sbjct: 293 QT--SGAFGGAFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVP 350

Query: 178 LFLMGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMP 224
           L L+ +F +KI     ++ N + +     FG  +L + + L++  +P
Sbjct: 351 LMLITLFGNKILPKSGEWMNTVKQ----TFGFVMLALPVFLLSRILP 393
>ref|NP_274527.1| (NC_003112) thiol:disulfide interchange protein DsbD [Neisseria
           meningitidis MC58]
 sp|Q9JYM0|DSBD_NEIMB Thiol:disulfide interchange protein dsbD precursor
 pir||F81074 thiol-disulfide interchange protein dsbD homolog NMB1519 [imported]
           - Neisseria meningitidis (group B strain MD58)
 gb|AAF41875.1| (AE002501) thiol:disulfide interchange protein DsbD [Neisseria
           meningitidis MC58]
          Length = 601

 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 49/225 (21%), Positives = 93/225 (40%), Gaps = 11/225 (4%)

Query: 6   NLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYM 65
           N + L  FLA L +S   C+     IVS+   +   K    +       +Y  G   TY 
Sbjct: 189 NANLLAFFLAGLGLSFTACMYPLLPIVSSI--VVGDKKAGKARAFVLSVVYVQGLALTYT 246

Query: 66  LLGAIAASLGHSLSVSMGFRGVLFISMGI-ILICLALLGARMEKLSFQIPFISFLMKKTL 124
           L+G +A   G  L+V +    V+  +  + +++ L++ G    +L   +          L
Sbjct: 247 LVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRL 306

Query: 125 QSQNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
               I+ ++ +G+L+  +  PC+   +   L  +  +  A +G +   +  LGT +PL  
Sbjct: 307 SGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIA 366

Query: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPH 225
           +G F   I      + N +       FG  +L + + L    +P+
Sbjct: 367 IGTFGGHILPKAGDWMNAVKY----AFGFILLAVAVYLATPHLPY 407
>ref|NP_284434.1| (NC_003116) putative disulphide isomerase [Neisseria meningitidis
           Z2491]
 pir||B81868 thiol-disulfide interchange protein dsbD homolog NMA1719
           [similarity] - Neisseria meningitidis (group A strain
           Z2491)
 emb|CAB84947.1| (AL162756) putative disulphide isomerase [Neisseria meningitidis
           Z2491]
          Length = 613

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 49/225 (21%), Positives = 93/225 (40%), Gaps = 11/225 (4%)

Query: 6   NLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYM 65
           N + L  FLA L +S   C+     IVS+   +   K    +       +Y  G   TY 
Sbjct: 201 NANLLAFFLAGLGLSFTACMYPLLPIVSSI--VVGDKKAGKARAFVLSVVYVQGLSLTYT 258

Query: 66  LLGAIAASLGHSLSVSMGFRGVLFISMGI-ILICLALLGARMEKLSFQIPFISFLMKKTL 124
           L+G +A   G  L+V +    V+  +  + +++ L++ G    +L   +          L
Sbjct: 259 LVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRL 318

Query: 125 QSQNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
               I+ ++ +G+L+  +  PC+   +   L  +  +  A +G +   +  LGT +PL  
Sbjct: 319 SGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIA 378

Query: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPH 225
           +G F   I      + N +       FG  +L + + L    +P+
Sbjct: 379 IGTFGGHILPRAGDWMNAVKY----AFGFILLAVAVYLATPHLPY 419
>sp|Q9JTL9|DSBD_NEIMA Thiol:disulfide interchange protein dsbD precursor
          Length = 601

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 49/225 (21%), Positives = 93/225 (40%), Gaps = 11/225 (4%)

Query: 6   NLSFLGMFLAALSMSLGHCVGMCGGIVSAFSQIRFSKVTSFSYQLTCHALYNVGRISTYM 65
           N + L  FLA L +S   C+     IVS+   +   K    +       +Y  G   TY 
Sbjct: 189 NANLLAFFLAGLGLSFTACMYPLLPIVSSI--VVGDKKAGKARAFVLSVVYVQGLSLTYT 246

Query: 66  LLGAIAASLGHSLSVSMGFRGVLFISMGI-ILICLALLGARMEKLSFQIPFISFLMKKTL 124
           L+G +A   G  L+V +    V+  +  + +++ L++ G    +L   +          L
Sbjct: 247 LVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRL 306

Query: 125 QSQNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFL 180
               I+ ++ +G+L+  +  PC+   +   L  +  +  A +G +   +  LGT +PL  
Sbjct: 307 SGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIA 366

Query: 181 MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMPH 225
           +G F   I      + N +       FG  +L + + L    +P+
Sbjct: 367 IGTFGGHILPRAGDWMNAVKY----AFGFILLAVAVYLATPHLPY 407
>ref|NP_245158.1| (NC_002663) DsbD [Pasteurella multocida]
 gb|AAK02305.1| (AE006056) DsbD [Pasteurella multocida]
          Length = 586

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 60/225 (26%), Positives = 98/225 (42%), Gaps = 26/225 (11%)

Query: 13  FLAALSMSLGHCVGMCGGIVSAF---SQIRFSKVTSFSYQLTCHALYNVGRISTYMLLGA 69
           FL  L ++   CV     ++SA     + R S   +F   +    +Y  G   TY LLG 
Sbjct: 192 FLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSV----VYVQGMALTYTLLGL 247

Query: 70  IAASLGHSLSVSMGFRGVLF-ISMGIILICLALLGARMEKLSFQIPFISFLMKKTLQSQN 128
           I A++G    V++    VL  +S   +L+ L++ G      + Q+P +S   K T  SQ 
Sbjct: 248 IVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGL----FTLQLP-VSLQTKLTQYSQQ 302

Query: 129 -----ILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLF 179
                  G++ +G++ G +  PC    +   L  V  S   F GA+      LG  +PL 
Sbjct: 303 QKSGVFGGVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLI 362

Query: 180 LMGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMP 224
            + +F + I     K  N + ++    FG  +L + I LI+   P
Sbjct: 363 FITVFGNNI---LPKSGNWMIQV-KNAFGFVLLALPIFLISRVFP 403
>sp|Q9CP40|DSBD_PASMU Thiol:disulfide interchange protein dsbD precursor
          Length = 576

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 60/225 (26%), Positives = 98/225 (42%), Gaps = 26/225 (11%)

Query: 13  FLAALSMSLGHCVGMCGGIVSAF---SQIRFSKVTSFSYQLTCHALYNVGRISTYMLLGA 69
           FL  L ++   CV     ++SA     + R S   +F   +    +Y  G   TY LLG 
Sbjct: 182 FLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSV----VYVQGMALTYTLLGL 237

Query: 70  IAASLGHSLSVSMGFRGVLF-ISMGIILICLALLGARMEKLSFQIPFISFLMKKTLQSQN 128
           I A++G    V++    VL  +S   +L+ L++ G      + Q+P +S   K T  SQ 
Sbjct: 238 IVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGL----FTLQLP-VSLQTKLTQYSQQ 292

Query: 129 -----ILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLF 179
                  G++ +G++ G +  PC    +   L  V  S   F GA+      LG  +PL 
Sbjct: 293 QKSGVFGGVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLI 352

Query: 180 LMGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMP 224
            + +F + I     K  N + ++    FG  +L + I LI+   P
Sbjct: 353 FITVFGNNI---LPKSGNWMIQV-KNAFGFVLLALPIFLISRVFP 393
>ref|NP_232328.1| (NC_002505) thiol:disulfide interchange protein DsbD [Vibrio
           cholerae]
 sp|Q9KNN1|DSBD_VIBCH Thiol:disulfide interchange protein dsbD precursor
 pir||A82043 inner membrane copper tolerance protein cycZ VC2701 [similarity] -
           Vibrio cholerae (group O1 strain N16961)
 gb|AAF95841.1| (AE004336) thiol:disulfide interchange protein DsbD [Vibrio
           cholerae]
          Length = 600

 Score = 44.7 bits (104), Expect = 0.001
 Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 9/180 (5%)

Query: 50  LTCHALYNVGRISTYMLLGAIAASLGHSLSVSMGFRGVLF-ISMGIILICLALLGARMEK 108
           L    +Y  G   TY LLG + AS G     ++    VL  +S+  + + L++ G    +
Sbjct: 238 LLLSVIYVQGMALTYTLLGLVVASAGLQFQAALQHPYVLMGLSVLFVALALSMFGLYSLQ 297

Query: 109 LSFQIPFISFLMKKTLQSQNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGA 164
           L   +      +    Q  ++ G++ +G ++G +  PC    +   L  V  S     GA
Sbjct: 298 LPSGVQTWLNSLSNAQQGGSLPGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGA 357

Query: 165 MLGLSFGLGTSMPLFLMGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKMP 224
           +   +  +G  +PL L+ +F +K+     K  N + ++   +FG  +L   I L+   +P
Sbjct: 358 VALYALAIGMGIPLILVAVFGNKL---LPKAGNWMERV-KTLFGFVLLAAPIFLLERIVP 413
>ref|NP_111234.1| (NC_002689) Predicted threonine efflux protein [Thermoplasma
           volcanium]
 dbj|BAB59857.1| (AP000993) hypothetical protein [Thermoplasma volcanium]
          Length = 186

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 29/104 (27%), Positives = 59/104 (55%), Gaps = 9/104 (8%)

Query: 120 MKKTLQSQNILGLYFLGVLNGFL-PCMMVYSFLASV-ILSHSAFMGAMLGLSFGLGTSMP 177
           +KK+ + +   G YF+G+L G   P  +++   A + +++H + +G      FGL + + 
Sbjct: 87  LKKSSRYKTRRGNYFVGLLVGISNPFQIIWWVTAGLFVVNHMSLIGV-----FGLFSGVV 141

Query: 178 LFL--MGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLI 219
           L++     F++K +  Y K+  + S +++  FG+YIL +GI +I
Sbjct: 142 LWITIFPFFVNKYAKRYEKYVRIASSVVLISFGVYILIVGIKVI 185
>ref|NP_634469.1| (NC_003901) conserved protein [Methanosarcina mazei Goe1]
 gb|AAM32141.1| (AE013488) conserved protein [Methanosarcina mazei Goe1]
          Length = 287

 Score = 41.6 bits (96), Expect = 0.008
 Identities = 44/165 (26%), Positives = 75/165 (44%), Gaps = 12/165 (7%)

Query: 55  LYNVGRISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILICLALLGARMEKLSFQIP 114
           ++ +G + +Y+LLG    S   S+     F  V  I   +ILI L LLG     +     
Sbjct: 127 VFGLGLVGSYLLLGLCLLSFRKSIPDLESFSFVTGII--VILIGLNLLGILKSPVVLDNY 184

Query: 115 FISFLMKKTLQSQNILGLYFLGVLNGFL--PCMM-VYSFLASVILSHSAFMGAMLGLSFG 171
           F S   K    +  + G++FLG+L  F+  PC   +   L +  +++       L L+F 
Sbjct: 185 FQSSARK---YAGTLGGVFFLGILFSFVKVPCTAPMLLVLLNKTITNGTVNDLALLLAFS 241

Query: 172 LGTSMPLFLMGIF----LSKISVSYRKFFNLLSKILMGVFGLYIL 212
            G   P   +G+     LSK   SY+ +   +S  ++ + GL+I+
Sbjct: 242 GGVLTPFIGVGMIGGYTLSKQIRSYKMYLKKISGFVLILLGLWIM 286
>ref|NP_222971.1| (NC_000921) putative CYTOCHROME C-TYPE BIOGENESIS PROTEIN
           [Helicobacter pylori J99]
 pir||D71956 probable holocytochrome-c synthase (EC 4.4.1.17) ccdA -
           Helicobacter pylori (strain J99)
 gb|AAD05826.1| (AE001462) putative CYTOCHROME C-TYPE BIOGENESIS PROTEIN
           [Helicobacter pylori J99]
          Length = 239

 Score = 41.6 bits (96), Expect = 0.008
 Identities = 38/171 (22%), Positives = 81/171 (47%), Gaps = 8/171 (4%)

Query: 55  LYNVGRISTYMLLGAIAASLGHSLSVSMGFRGVLFISMGIILIC-LALLGARMEKLSFQI 113
           ++ VG    ++ +G   A L HS S    F  V +I+ GI+++  L  LG       ++ 
Sbjct: 66  MFVVGFSLVFLGVGMSMAKLIHSFS----FSWVNYIAGGIVILFGLHFLGVFRFAFLYKT 121

Query: 114 PFISFLMKKTLQSQNILGLYFLGVLNGFLPCM-MVYSFLASVILSHSAFMGAMLGLSFGL 172
             +    K     +    L  +    G+ PC+  +++ +  +  S  A+ G ML + F +
Sbjct: 122 QSVGLASKSNSMQRFYPFLLGMSFALGWTPCIGPIFTSIVIMSASKDAY-GLMLMVVFVM 180

Query: 173 GTSMPLFLMGIFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLINHKM 223
           G ++P  L+ + L + ++ + K     ++ +  V GL ++ MGI+++ + +
Sbjct: 181 GLAIPFLLVALMLER-ALLFLKSLRKYNRAIEIVSGLVLILMGILIMTNSL 230
>sp|Q9KJZ3|DSBD_PSESP Thiol:disulfide interchange protein dsbD precursor
 gb|AAF80267.1|AF155506_1 (AF155506) putative disulfide isomerase DsbD [Pseudomonas sp. JR1]
          Length = 578

 Score = 41.6 bits (96), Expect = 0.008
 Identities = 52/217 (23%), Positives = 91/217 (40%), Gaps = 21/217 (9%)

Query: 10  LGMFLAALSMSLGHCVGMCGGIVSAFSQIR--FSKVTSFSYQLTCHALYNVGRISTYMLL 67
           LG+ LA    SL     + G IV + +  +  F+  TS          Y V     Y  +
Sbjct: 170 LGLLLAFTPCSLPMLPILAGLIVGSGATPKRGFALATS----------YVVSMALVYAAM 219

Query: 68  GAIAASLGHSLSVSMGFRGVLFISMGI-ILICLALLGARMEKLSFQIPFISFLMKKTLQS 126
           G +AA LG +L   +    +L     + +L+ L + G    +L   +      + +  + 
Sbjct: 220 GVLAAMLGANLQALLQNPWLLGSFAAVFVLLALPMFGFFELQLPVAVRDRLENVSRNQRG 279

Query: 127 QNILGLYFLGVLNGFL--PCMM--VYSFLASVILSHSAFMGAMLGLSFGLGTSMPLFLMG 182
            ++ G   LG L+G L  PCM   +   L  +  S +A  G ++  + G+G  +PL L+ 
Sbjct: 280 GSLFGAGVLGALSGLLVGPCMTAPLAGALLYIAQSGNALHGGLILFAMGIGIGVPLLLLV 339

Query: 183 IFLSKISVSYRKFFNLLSKILMGVFGLYILYMGIMLI 219
              ++       + NLL     GVFG   L   ++++
Sbjct: 340 TVGNRFLPKPGAWMNLLK----GVFGFLFLATALLML 372
  Database: /home/scwang/download_20020708_db/nr
    Posted date:  Aug 7, 2002 12:55 PM
  Number of letters in database: 324,149,939
  Number of sequences in database:  1,026,957
  
Lambda     K      H
   0.333    0.143    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 135,948,397
Number of Sequences: 1026957
Number of extensions: 5186173
Number of successful extensions: 29490
Number of sequences better than 1.0e-02: 22
Number of HSP's better than  0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 29451
Number of HSP's gapped (non-prelim): 23
length of query: 246
length of database: 324,149,939
effective HSP length: 118
effective length of query: 128
effective length of database: 202,969,013
effective search space: 25980033664
effective search space used: 25980033664
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 96 (41.6 bits)